Novel (E)-α-[(1H-indol-3-yl)methylene]benzeneacetic acids as endothelin receptor ligands

Farmaco

Volumn 60, Issue 9, 2005, Pages 731-738

  Pittalà, Valeria ^a   Romeo, Giuseppe ^a   Materia, Luisa ^a   Salerno, Loredana ^a   Siracusa, Maria Angela ^a   Modica, Maria ^a   Mereghetti, Ilario ^b   Cagnotto, Alfredo ^b   Russo, Filippo ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

(E) (1H indol 3 ylmethylene)benzeneacetic acid derivatives; Endothelin receptors; G Protein coupled receptors; Hypertension

Indexed keywords

ALPHA [(1 ACETYL 1H INDOL 3 YL)METHYLENE] 1,3 BENZODIOXOL 5 YLACETIC ACID; ALPHA [(1 ACETYL 1H INDOL 3 YL)METHYLENE] 3,4 DIMETHOXYBENZENEACETIC ACID; ALPHA [(1 ACETYL 1H INDOL 3 YL)METHYLENE] 4 METHOXYBENZENEACETIC ACID; ALPHA [(1 ACETYL 1H INDOL 3 YL)METHYLENE] 4 METHYLBENZENEACETIC ACID; ALPHA [(1 ACETYL 1H INDOL 3 YL)METHYLENE]BENZENEACETIC ACID; ALPHA [(1H INDOL 3 YL)METHYLENE] 1,3 BENZODIOXOL 5 YLACETIC ACID; ALPHA [(1H INDOL 3 YL)METHYLENE] 3,4 DIMETHOXYBENZENEACETIC ACID; ALPHA [(1H INDOL 3 YL)METHYLENE] 4 METHOXYBENZENEACETIC ACID; ALPHA [(1H INDOL 3 YL)METHYLENE] 4 METHYLBENZENEACETIC ACID; ALPHA [(1H INDOL 3 YL)METHYLENE]BENZENEACETIC ACID; ALPHA [[1 (1,3 BENZODIOXOL 5 YLMETHYL) 1H INDOL 3 YL]METHYLENE] 1,3 BENZODIOXOL 5 YLACETIC ACID; ALPHA [[1 (1,3 BENZODIOXOL 5 YLMETHYL) 1H INDOL 3 YL]METHYLENE] 3,4 DIMETHOXYBENZENEACETIC ACID; ALPHA [[1 (1,3 BENZODIOXOL 5 YLMETHYL) 1H INDOL 3 YL]METHYLENE] 4 METHOXYBENZENEACETIC ACID; ALPHA [[1 (1,3 BENZODIOXOL 5 YLMETHYL) 1H INDOL 3 YL]METHYLENE] 4 METHYLBENZENEACETIC ACID; ALPHA [[1 (1,3 BENZODIOXOL 5 YLMETHYL) 1H INDOL 3 YL]METHYLENE] BENZENEACETIC ACID; ALPHA [[1 (2 METHOXYPHENYLMETHYL) 1H INDOL 3 YL]METHYLENE] 4 METHYLBENZENEACETIC ACID; ALPHA [[1 (3,4 DIMETHOXYPHENYLMETHYL) 1H INDOL 3 YL]METHYLENE] 3,4 DIMETHOXYBENZENEACETIC ACID; ALPHA [[1 (4 METHOXYPHENYLMETHYL) 1H INDOL 3 YL]METHYLENE] 1,3 BENZODIOXOL 5 YLACETIC ACID; ALPHA [[1 (4 METHOXYPHENYLMETHYL) 1H INDOL 3 YL]METHYLENE] 3,4 DIMETHOXYBENZENEACETIC ACID; ALPHA [[1 (4 METHOXYPHENYLMETHYL) 1H INDOL 3 YL]METHYLENE] 4 METHOXYBENZENEACETIC ACID; ALPHA [[1 (4 METHOXYPHENYLMETHYL) 1H INDOL 3 YL]METHYLENE] 4 METHYLBENZENEACETIC ACID; ALPHA [[1 (4 METHOXYPHENYLMETHYL) 1H INDOL 3 YL]METHYLENE]BENZENEACETIC ACID; ALPHA [[1 (4 METHYLTHIOPHENYLMETHYL) 1H INDOL 3 YL]METHYLENE] 3,4 DIMETHOXYBENZENEACETIC ACID; ENDOTHELIN RECEPTOR; LIGAND; PHENYLACETIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN;

ACETIC ACID; ANIMALS; CHO CELLS; CRICETINAE; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY, INFRARED;

EID: 24944572258     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2005.06.010     Document Type: Article

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