-
1
-
-
0030030379
-
Requirement of mammalian DNA polymerase-β in base-excision repair
-
R.W. Sobol, J.K. Horton, R. Kuhn, H. Gu, R.K. Singhal, R. Prasad, K. Rajewsky, and S.H. Wilson Requirement of mammalian DNA polymerase-β in base-excision repair Nature 379 1996 183 186
-
(1996)
Nature
, vol.379
, pp. 183-186
-
-
Sobol, R.W.1
Horton, J.K.2
Kuhn, R.3
Gu, H.4
Singhal, R.K.5
Prasad, R.6
Rajewsky, K.7
Wilson, S.H.8
-
2
-
-
0037413370
-
Hypersensitivity of DNA polymerase β null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions
-
J.K. Horton, D.F. Joyce-Gray, B.F. Pachkowski, J.A. Swenberg, and S.H. Wilson Hypersensitivity of DNA polymerase β null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions DNA Repair 2 2003 27 48
-
(2003)
DNA Repair
, vol.2
, pp. 27-48
-
-
Horton, J.K.1
Joyce-Gray, D.F.2
Pachkowski, B.F.3
Swenberg, J.A.4
Wilson, S.H.5
-
4
-
-
18144413027
-
Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest following DNA methylating agent exposure
-
J.K. Horton, D.F. Stefanick, J.M. Naron, P.S. Kedar, and S.H. Wilson Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest following DNA methylating agent exposure J. Biol. Chem. 280 2005 15773 15785
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 15773-15785
-
-
Horton, J.K.1
Stefanick, D.F.2
Naron, J.M.3
Kedar, P.S.4
Wilson, S.H.5
-
5
-
-
0035816708
-
Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair
-
O.I. Lavrik, R. Prasad, R.W. Sobol, J.K. Horton, E.J. Ackerman, and S.H. Wilson Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair J. Biol. Chem. 276 2001 25541 25548
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25541-25548
-
-
Lavrik, O.I.1
Prasad, R.2
Sobol, R.W.3
Horton, J.K.4
Ackerman, E.J.5
Wilson, S.H.6
-
6
-
-
0038449141
-
PARP-1, a determinant of cell survival in response to DNA damage
-
V.J. Bouchard, M. Rouleau, and G.G. Poirier PARP-1, a determinant of cell survival in response to DNA damage Exp. Hematol. 31 2003 446 454
-
(2003)
Exp. Hematol.
, vol.31
, pp. 446-454
-
-
Bouchard, V.J.1
Rouleau, M.2
Poirier, G.G.3
-
7
-
-
0028865245
-
Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks
-
T. Lindahl, M.S. Satoh, G.G. Poirier, and A. Klungland Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks Trends Biochem. Sci. 20 1995 405 411
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 405-411
-
-
Lindahl, T.1
Satoh, M.S.2
Poirier, G.G.3
Klungland, A.4
-
8
-
-
0037193540
-
Involvement of DNA polymerase β in protection against the cytotoxicity of oxidative damage
-
J.K. Horton, A. Baker, B.J. Vande Berg, R.W. Sobol, and S.H. Wilson Involvement of DNA polymerase β in protection against the cytotoxicity of oxidative damage DNA Repair 1 2002 317 333
-
(2002)
DNA Repair
, vol.1
, pp. 317-333
-
-
Horton, J.K.1
Baker, A.2
Vande Berg, B.J.3
Sobol, R.W.4
Wilson, S.H.5
-
9
-
-
0021997074
-
Poly(ADP-ribose) in the cellular response to DNA damage
-
N.A. Berger Poly(ADP-ribose) in the cellular response to DNA damage Radiat. Res. 101 1985 4 15
-
(1985)
Radiat. Res.
, vol.101
, pp. 4-15
-
-
Berger, N.A.1
-
10
-
-
0033598713
-
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
-
H.C. Ha, and S.H. Snyder Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion Proc. Natl. Acad. Sci. U.S.A. 96 1999 13978 13982
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13978-13982
-
-
Ha, H.C.1
Snyder, S.H.2
-
11
-
-
20444386251
-
Inhibition of PARP prevents oxidant-induced necrosis but not apoptosis in LLC-PK1 cells
-
D.M. Filipovic, X. Meng, and W.B. Reeves Inhibition of PARP prevents oxidant-induced necrosis but not apoptosis in LLC-PK1 cells Am. J. Physiol. 277 1999 428 436
-
(1999)
Am. J. Physiol.
, vol.277
, pp. 428-436
-
-
Filipovic, D.M.1
Meng, X.2
Reeves, W.B.3
-
12
-
-
0033957359
-
Morphologic and biochemical hallmarks of apoptosis
-
A. Saraste, and K. Pulkki Morphologic and biochemical hallmarks of apoptosis Cardiovasc. Res. 45 2000 528 537
-
(2000)
Cardiovasc. Res.
, vol.45
, pp. 528-537
-
-
Saraste, A.1
Pulkki, K.2
-
13
-
-
0032575714
-
Death receptors: Signaling and modulation
-
A. Ashkenazi, and V.M. Dixit Death receptors: signaling and modulation Science 281 1998 1305 1308
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
14
-
-
0034105784
-
Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes
-
K. Cain, S.B. Bratton, C. Langlais, G. Walker, D.G. Brown, X.M. Sun, and G.M. Cohen Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes J. Biol. Chem. 275 2000 6067 6070
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6067-6070
-
-
Cain, K.1
Bratton, S.B.2
Langlais, C.3
Walker, G.4
Brown, D.G.5
Sun, X.M.6
Cohen, G.M.7
-
15
-
-
0021763935
-
Preparing nuclei from cells in monolayer cultures suitable for counting and for following synchronized cells through the cell cycle
-
W.B. Butler Preparing nuclei from cells in monolayer cultures suitable for counting and for following synchronized cells through the cell cycle Anal. Biochem. 141 1984 70 73
-
(1984)
Anal. Biochem.
, vol.141
, pp. 70-73
-
-
Butler, W.B.1
-
16
-
-
0029043888
-
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
-
I. Vermes, C. Haanen, H. Steffens-Nakken, and C. Reutelingsperger A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V J. Immunol. Methods 184 1995 39 51
-
(1995)
J. Immunol. Methods
, vol.184
, pp. 39-51
-
-
Vermes, I.1
Haanen, C.2
Steffens-Nakken, H.3
Reutelingsperger, C.4
-
17
-
-
0036644080
-
Quantitation of mitochondrial alterations associated with apoptosis
-
M. Castedo, K. Ferri, T. Roumier, D. Metivier, N. Zamzami, and G. Kroemer Quantitation of mitochondrial alterations associated with apoptosis J. Immunol. Methods 265 2002 39 47
-
(2002)
J. Immunol. Methods
, vol.265
, pp. 39-47
-
-
Castedo, M.1
Ferri, K.2
Roumier, T.3
Metivier, D.4
Zamzami, N.5
Kroemer, G.6
-
19
-
-
0033118432
-
Cells deficient in DNA polymerase β are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage
-
K. Ochs, R.W. Sobol, S.H. Wilson, and B. Kaina Cells deficient in DNA polymerase β are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage Cancer Res. 59 1999 1544 1551
-
(1999)
Cancer Res.
, vol.59
, pp. 1544-1551
-
-
Ochs, K.1
Sobol, R.W.2
Wilson, S.H.3
Kaina, B.4
-
20
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
W.X. Zong, D. Ditsworth, D.E. Bauer, Z.Q. Wang, and C.B. Thompson Alkylating DNA damage stimulates a regulated form of necrotic cell death Genes Dev. 18 2004 1272 1282
-
(2004)
Genes Dev.
, vol.18
, pp. 1272-1282
-
-
Zong, W.X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.Q.4
Thompson, C.B.5
-
21
-
-
0034897316
-
Poly(ADP-ribose) polymerase inhibitor increases apoptosis and reduces necrosis induced by a DNA minor groove binding methyl sulfonate ester
-
L. Tentori, A. Balduzzi, I. Portarena, L. Levati, P. Vernole, B. Gold, E. Bonmassar, and G. Graziani Poly(ADP-ribose) polymerase inhibitor increases apoptosis and reduces necrosis induced by a DNA minor groove binding methyl sulfonate ester Cell Death Differ. 8 2001 817 828
-
(2001)
Cell Death Differ.
, vol.8
, pp. 817-828
-
-
Tentori, L.1
Balduzzi, A.2
Portarena, I.3
Levati, L.4
Vernole, P.5
Gold, B.6
Bonmassar, E.7
Graziani, G.8
-
22
-
-
0028826231
-
Potentiation of temozolomide-induced cytotoxicity: A comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors
-
S. Boulton, L.C. Pemberton, J.K. Porteous, N.J. Curtin, R.J. Griffin, B.T. Golding, and B.W. Durkacz Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors Br. J. Cancer 72 1995 849 856
-
(1995)
Br. J. Cancer
, vol.72
, pp. 849-856
-
-
Boulton, S.1
Pemberton, L.C.2
Porteous, J.K.3
Curtin, N.J.4
Griffin, R.J.5
Golding, B.T.6
Durkacz, B.W.7
-
23
-
-
0036793612
-
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells
-
L. Tentori, I. Portarena, F. Torino, M. Scerrati, P. Navarra, and G. Graziani Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells Glia 40 2002 44 54
-
(2002)
Glia
, vol.40
, pp. 44-54
-
-
Tentori, L.1
Portarena, I.2
Torino, F.3
Scerrati, M.4
Navarra, P.5
Graziani, G.6
-
24
-
-
10744233684
-
Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma
-
L. Tentori, C. Leonetti, M. Scarsella, G. D'Amati, M. Vergati, I. Portarena, W. Xu, V. Kalish, G. Zupi, J. Zhang, and G. Graziani Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma Clin. Cancer Res. 9 2003 5370 5379
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5370-5379
-
-
Tentori, L.1
Leonetti, C.2
Scarsella, M.3
D'Amati, G.4
Vergati, M.5
Portarena, I.6
Xu, W.7
Kalish, V.8
Zupi, G.9
Zhang, J.10
Graziani, G.11
-
25
-
-
10744226451
-
Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361
-
C.R. Calabrese, R. Almassy, S. Barton, M.A. Batey, A.H. Calvert, S. Canan-Koch, B.W. Durkacz, Z. Hostomsky, R.A. Kumpf, S. Kyle, J. Li, K. Maegley, D.R. Newell, E. Notarianni, I.J. Stratford, D. Skalitzky, H.D. Thomas, L.Z. Wang, S.E. Webber, K.J. Williams, and N.J. Curtin Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361 J. Natl. Cancer Inst. 96 2004 56 67
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 56-67
-
-
Calabrese, C.R.1
Almassy, R.2
Barton, S.3
Batey, M.A.4
Calvert, A.H.5
Canan-Koch, S.6
Durkacz, B.W.7
Hostomsky, Z.8
Kumpf, R.A.9
Kyle, S.10
Li, J.11
Maegley, K.12
Newell, D.R.13
Notarianni, E.14
Stratford, I.J.15
Skalitzky, D.16
Thomas, H.D.17
Wang, L.Z.18
Webber, S.E.19
Williams, K.J.20
Curtin, N.J.21
more..
-
26
-
-
2942515038
-
Activation of intrinsic and extrinsic pathways in apoptotic signaling during UV-C-induced death of Jurkat cells: The role of caspase inhibition
-
A.B. Scoltock, and J.A. Cidlowski Activation of intrinsic and extrinsic pathways in apoptotic signaling during UV-C-induced death of Jurkat cells: the role of caspase inhibition Exp. Cell Res. 297 2004 212 223
-
(2004)
Exp. Cell Res.
, vol.297
, pp. 212-223
-
-
Scoltock, A.B.1
Cidlowski, J.A.2
-
27
-
-
0033975054
-
An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage
-
J.R. Jackson, A. Gilmartin, C. Imburgia, J.D. Winkler, L.A. Marshall, and A. Roshak An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage Cancer Res. 60 2000 566 572
-
(2000)
Cancer Res.
, vol.60
, pp. 566-572
-
-
Jackson, J.R.1
Gilmartin, A.2
Imburgia, C.3
Winkler, J.D.4
Marshall, L.A.5
Roshak, A.6
-
28
-
-
0035422203
-
2 checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells
-
2 checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells Cancer Res. 61 2001 5843 5849
-
(2001)
Cancer Res.
, vol.61
, pp. 5843-5849
-
-
Hirose, Y.1
Berger, M.S.2
Pieper, R.O.3
-
29
-
-
0012365397
-
A novel indolocarbazole, ICP-1, abrogates DNA damage-induced cell cycle arrest and enhances cytotoxicity: Similarities and differences to the cell cycle checkpoint abrogator UCN-01
-
A. Eastman, E.A. Kohn, M.K. Brown, J. Rathman, M. Livingstone, D.H. Blank, and G.W. Gribble A novel indolocarbazole, ICP-1, abrogates DNA damage-induced cell cycle arrest and enhances cytotoxicity: similarities and differences to the cell cycle checkpoint abrogator UCN-01 Mol. Cancer Ther. 1 2002 1067 1078
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 1067-1078
-
-
Eastman, A.1
Kohn, E.A.2
Brown, M.K.3
Rathman, J.4
Livingstone, M.5
Blank, D.H.6
Gribble, G.W.7
-
30
-
-
2942599254
-
Abrogation of Chk1-mediated S/G2 checkpoint by UCN-01 enhances ara-C-induced cytotoxicity in human colon cancer cells
-
R.-G. Shao, C.X. Cao, and Y. Pommier Abrogation of Chk1-mediated S/G2 checkpoint by UCN-01 enhances ara-C-induced cytotoxicity in human colon cancer cells Acta Pharmacol. Sin. 25 2004 756 762
-
(2004)
Acta Pharmacol. Sin.
, vol.25
, pp. 756-762
-
-
Shao, R.-G.1
Cao, C.X.2
Pommier, Y.3
|