Reducing the impact of binding of UCN-01 to human α1-acid glycoprotein by encapsulation in liposomes

Biological and Pharmaceutical Bulletin

Volumn 28, Issue 7, 2005, Pages 1259-1264

  Yamauchi, Masahiro ^a   Kusano, Hiroko ^a   Nakakura, Masashi ^a   Kato, Yasuki ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

Alpha 1 acid glycoprotein; Chromatography; Encapsulation; Liposome; Pharmacokinetics; Protein binding

Indexed keywords

7 HYDROXYSTAUROSPORINE; LIPOSOME; OROSOMUCOID;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG RELEASE; ENCAPSULATION; GEL CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT;

ANIMALS; HUMANS; LIPOSOMES; MALE; OROSOMUCOID; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; STAUROSPORINE;

EID: 24944552991     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.28.1259     Document Type: Article

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