Informatics approaches to functional MRI odor mapping of the rodent olfactory bulb: OdorMapBuilder and OdorMapDB

Neuroinformatics

Volumn 2, Issue 1, 2004, Pages 3-18

  Liu, Nian ^a   Xu, Fuqiang ^a   Marenco, Luis ^a   Hyder, Fahmeed ^a   Miller, Perry ^a   Shepherd, Gordon M ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glomerular layer; Java; Neuroinformatics; Odor map; Spatial activity pattern; Web based database

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DATA BASE; IMAGE ANALYSIS; INFORMATION SYSTEM; NEUROBIOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OLFACTORY BULB; OLFACTORY DISCRIMINATION; PRIORITY JOURNAL; RAT; SENSORY STIMULATION; SMELLING; SPATIAL AUTOCORRELATION ANALYSIS; STIMULUS RESPONSE;

EID: 2942744332     PISSN: 15392791     EISSN: None     Source Type: Journal    
DOI: 10.1385/ni:2:1:003     Document Type: Article

References (24)

1. Adrian, E. D. (1950) Sensory discrimination, with some recent evidence from the olfactory organ. Br. Med. Bull. 6, 330-333.
2. Chicurel, M. (2000) Databasing the brain. Nature 406, 822-825.
3. Fissell, K., Tseytlin, E., Cunningham, D., et al. (2003) Fiswidgets: A graphical computing environment for neuroimaging analysis. Neuroinformatics 1, 111-126.
4. Guthrie, K. M., Anderson, A. J., Leon, M., and Gall, C. (1993) Odor-induced increases in c-fos mRNA expression reveal an anatomical "unit" for odor processing in olfactory bulb. Proc. Natl. Acad. Sci. USA 90, 3329-3333.
5. Huerta, M. F., Koslow, S. H., and Leshner, A. I. (1993) The Human Brain Project: an international resource. Trends Neurosci. 16, 436-438.
6. Johnson, S.B. (1996) Generic data modeling for clinical repositories. J. Am. Med. Inform. Assoc. 3, 328-339.
7. Johnson, B.A., Woo, C.C., Hingco, E.E., Pham, K.L., and Leon, M. (1999) Multidimensional chemotopic responses to n-aliphatic acid odorants in the rat olfactory bulb. J. Comp. Neurol. 409, 529-548.
8. Johnson, B.A. and Leon, M. (2000) Modular representations of odorants in the glomerular layer of the rat olfactory bulb. J. Comp. Neurol. 422, 496-509.
9. Liu, N., Cigola, E., Tinti, C., et al. (1999) Unique regulation of immediate early gene and tyrosine hydroxylase expression in the odor-deprived mouse olfactory bulb. J. Biol. Chem. 274, 3042-3047.
10. Mombaerts, P., Wang, F., Dulac, C., et al. (1996) Visualizing an olfactory sensory map. Cell 87, 675-686.
11. Nadkarni, P., Brandt, C., Frawley, S.M., et al. (1998) Managing attribute-value clinical trials data using the ACT/DB client system. J. Am. Med. Inform. Assoc. 5, 139-151.
12. Nadkarni, P., Marenco, L., Chen, R., Skoufos, E., Shepherd, G., and Miller, P. (1999) Organization of heterogeneous scientific data using the EAV/CR representation. J. Am. Med. Inform. Assoc. 6, 478-493.
13. Niemeyer, P. and Peck, J. (1997) Exploring JAVA, 2nd ed., O'Reilly & Associates, Sebastopol, CA.
14. Royet, J. P., Sicard, G., Souchier, C., and Jourdan, F. (1987) Specificity of spatial patterns of glomerular activation in the mouse olfactory bulb: computer-assisted image analysis of 2-deoxyglucose autoradiograms. Brain Res. 417, 1-11.
15. Rubin, B. D. and Katz, L. C. (1999) Optical imaging of odorant representations in the mammalian olfactory bulb. Neuron 23, 499-511.
16. Sallaz, M. and Jourdan, F. (1993) C-fos expression and 2-deoxyglucose uptake in the olfactory bulb of odour-stimulated awake rats. Neuroreport 4, 55-58.
17. Shepherd, G. M. (1985) The olfactory system: the uses of neural space for a non-spatial modality. Prog. Clin. Biol. Res. 176, 99-114.
18. Stewart, W. B., Kauer, J. S., and Shepherd, G. M. (1979) Functional organization of rat olfactory bulb analysed by the 2-deoxyglucose method. J. Comp. Neurol. 185, 715-734.
19. Toga, A. W. (2002) Neuroimage databases: the good, the bad and the ugly. Nat. Rev. Neurosci. 3, 302-308.
20. Van Essen, D. C., Lewis, J. W., Drury, H. A., et al. (2001) Mapping visual cortex in monkeys and humans using surface-based atlases. Vision Res. 41, 1359-1378.
21. Wilson, D. A. and Leon, M. (1988) Spatial patterns of olfactory bulb single-unit responses to learned olfactory cues in young rats. J. Neurophysiol. 59, 1770-1782.
22. Xu, F., Greer, C. A., and Shepherd, G. M. (2000a) Odor maps in the olfactory bulb. J. Comp. Neurol. 422, 489-495.
23. Xu, F., Kida, I., Hyder, F., and Shulman, R. G. (2000b) Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI. Proc. Natl. Acad. Sci. USA 97, 10601-10606.
24. Yang, X., Renken, R., Hyder, F., et al. (1998) Dynamic mapping at the laminar level of odor-elicited responses in rat olfactory bulb by functional MRI. Proc. Natl. Acad. Sci. USA 95, 7715-7720.