Silicon microneedle electrode array with temperature monitoring for electroporation

Sensors and Actuators, A: Physical

Volumn 123-124, Issue , 2005, Pages 319-325

  Wilke, N ^a   Hibert, C ^a   O'Brien, J ^a   Morrissey, A ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Drug delivery; Electroporation; Microneedles; Microsystem; Silicon etching; Temperature sensor

Indexed keywords

ARRAYS; FLUIDICS; SENSORS; SILICON; SILICON WAFERS; TEMPERATURE MEASUREMENT;

ELECTRODE ARRAYS; FLUIDIC SYSTEMS; SILICON MICRONEEDLES; TEMPERATURE MONITORING;

ELECTRODES;

EID: 24944508964     PISSN: 09244247     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sna.2005.05.017     Document Type: Conference Paper

References (19)

1. J. Gehl REVIEW electroporation: theory and methods, perspectives for drug delivery, gene therapy and research Acta Physiol. Scand. 177 2003 437 447
2. Mark R. Prausnitz Microneedles for transdermal drug delivery Adv. Drug Deliv. Rev. 56 2004 581 587
3. G.A. Hofmann, S.B. Dev, S. Dimmer, and G.S. Nanda Electroporation therapy: a new approach for the treatment of head and neck cancer IEEE Trans. Biomed. Eng. 46 6 1999 752 759
4. Gerstel et al., Drug Delivery Device, US 3 964 482 patent, 1976.
5. E.V. Mukerjee, S.D. Collins, R.R. Isseroff, and R.L. Smith Microneedle array for transdermal biological fluid extraction and in situ analysis Sens. Actuators A 114 2004 267 275
6. E.V. Mukerjee, R.R. Issseroff, S.D. Collins, R.L. Smith, Microneedle array with integrated microchannels for transdermal sample extraction and in situ analysis, The 12th International Conference on Solid State Sensors, Actuators and Microsystems, Boston, 8-12 June 2003, pp. 1439-1441.
7. S.P. Davis, M.R. Prausnitz, M.G. Allen, Fabrication and characterisation of laser micromachined hollow microneedles, The 12th International Conference on Solid State Sensors, Actuators and Microsystems, Boston, 8-12 June 2003, pp. 1435-1438.
8. P. Griss, P. Enoksson, and G. Stemme Micromachined barbed spikes for mechanical chip attachment Sens. Actuators A 95 2002 94 99
9. P. Griss, and G. Stemme Side-opened out-of-plane microneedles for microfluidic transdermal liquid transfer J. Microelectromechanical Syst. 12 3 2003 296 301
10. J.G.E. Han, R. Gardeniers, E.J.W. Luttge, M.J. Berenschot, S.Y. de Boer, M. Yeshurun, R. Hefetz, A. van't Oever, and van den Berg Silicon micromachined hollow microneedles for transdermal liquid transport J. Microelectromechanical Sys. 12 6 2003 855 862
11. M.L. Reed, C. Wu, J. Kneller, S. Watkins, D.A. Vorp, A. Nadeem, L.E. Weiss, K. Rebello, M. Mescher, A.J. Smith, W. Rosenblum, and M.D. Feldman Micromechanical devices for intravascular drug delivery J. Pharm. Sci. 87 11 1998 1387 1394
12. S.E. Cross, and M.S. Roberts Physical enhancement of transdermal drug applications: is delivery technology keeping up with pharmaceutical development? Curr. Drug Delivery 1 2004 81 92
13. F. Chabri, K. Bouris, T. Jones, D. Barrow, A. Hann, C. Allender, K. Brain, and J. Birchall Microfabricated silicon microneedles for nonviral cutaneous gene delivery Br. J. Dermatol. 150 2004 869 877
14. M.L. Reed, Microsystems for drug and gene delivery, in: Proceedings of the IEEE, vol. 92, no. 1, January 2004, pp. 56-75.
15. G.T. Martin, U.F. Pliquett, and J.C. Weaver Theoretical analysis of localized heating in human skin subjected to high voltage pulses Bioelectrochemistry 57 2002 55 64
16. M. Shikida, M. Ando, Y. Ishihara, T. Ando, K. Sato, and K. Asaumi Non-photolithographic pattern transfer for fabricating pen-shaped microneedle structures J. Micromechanics Microeng. 14 2004 1462 1467
17. U. Pliquett Joule heating during solid tissue electroporation Med. Biol. Eng. Comput. 41 2003 215 219
18. D. Maillefer, S. Gamper, B. Frehner, P. Balmer, H. van Lintel, P. Renaud, A high-performance silicon micropump for disposable drug delivery systems, 0-7803-5998-4/01, 2001, pp. 413-417.
19. ENDOPORATOR, Development of microsystems for in vivo human gene therapy, EU FPS project reference number IST-2001-33141.