Effect of indole-3-acetic acid derivatives on neuroepithelium in rat embryos

Journal of Toxicological Sciences

Volumn 30, Issue 3, 2005, Pages 165-174

  Furukawa, Satoshi ^a   Usuda, Koji ^a   Abe, Masayoshi ^a   Ogawa, Izumi ^a  

^a NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

Author keywords

5 Methoxyindole 3 acetic acid; Apoptosis; Indole 3 acetic acid derivatives; Neuroepithelium; Rat

Indexed keywords

INDOLEACETIC ACID DERIVATIVE; INDOLEBUTYRIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; BRAIN WEIGHT; CONTROLLED STUDY; DRUG EFFECT; EMBRYO; EMBRYO CELL; EMBRYOTOXICITY; FEMALE; GESTATIONAL AGE; HISTOPATHOLOGY; LOCOMOTION; MICROCEPHALY; NEUROEPITHELIUM; NONHUMAN; RAT; RIGIDITY; TISSUE SECTION;

ANIMALIA;

EID: 24944437928     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.30.165     Document Type: Article

References (36)

1. Balemans, M.G., Noordegraaf, E.M., Bary, F.A. and van Berlo, M.F. (1978): Estimation of the methylating capacity of the pineal gland. With special reference to indole metabolism. Experientia, 15, 887-888.
2. Bandurski, R.S., Cohen, J.D., Slovin, J.P. and Reinecke, D.M. (1995): Hormone biosynthesis and metabolism. Auxin biosynthesis and metabolism. In Plant Hormones (Davies, P. J., ed.), pp. 39-63, Kluwer Academic Publishers, Dordrecht.
3. Bayer, S.A. and Altman, J. (2004): Development of the telencephalon: Neuroral stem cells, neurogenesis, and neuronal migration. In The rat. Nervous system. (Paxions, G., ed.), pp. 27-73, Elsevier Academic Press, San Diego.
4. Candeias, L.P., Folkes, L.K., Porssa, M., Parrick, J. and Wardman, P. (1995): Enhancement of lipid peroxidation by indole-3-acetic acid and derivatives: Substituent effects. Free Radic. Res., 23, 403-418.
5. Candeias, L.P., Folkes, L.K., Porssa, M., Parrick, J. and Wardman, P. (1996): Rates of reaction of indoleacetic acids with horseradish peroxidase compound I and their dependence on the redox potentials. Biochemistry, 9, 102-108.
6. Cattabeni, F. and Di Luca, M. (1997): Developmental models of brain dysfunctions induced by targeted cellular ablations with methylazoxymethanol. Physiol. Rev., 77, 199-215.
7. Chuman, H., Mori, A., Tanaka, H., Yamagami, C. and Fujita, T. (2004): Analyses of the partition coefficient, log P, using ab initio MO parameter and accessible surface area of solute molecules. J. Pharm. Sci., 93, 2681-2697.
8. De Melo, M.P.T., De Lima, M., Pithon-Curi, T.C. and Curi, R. (2004): The mechanism of indole acetic acid cytotoxicity. Toxicol. Lett., 148, 103-111.
9. Ferguson, S.A. and Holson, R.R. (1997). Methylazoxymethanol-induced microencephaly in the brown Norway strain: Behavior and brain weight. Int. J. Dev. Neurosci., 15, 75-86.
10. Folkes, L.K., Dennis, M.F., Stratford, M.R., Candeias, L. P. and Wardman, P. (1999): Peroxidase-catalyzed effects of indole-3-acetic acid and analogues on lipid membranes, DNA, and mammalian cells in vitro. Biochem. Pharmacol., 57, 375-382.
11. Folkes, L.K. and Wardman, P. (2001) Oxidative activation of indole-3-acetic acids to cytotoxic species - a potential new role for plant auxins in cancer therapy. Biochem. Pharmacol., 61, 129-136.
12. Furukawa, S., Abe, M., Usuda, K. and Ogawa, I. (2004): Indole-3-acetic acid induces microencephaly in rat fetuses. Tox. Pathol., 32, 659-667.
13. Gordon, S.A., Fry, R.J. and Barr, S. (1972): Origin or urinary auxin in the germfree and conventional mouse. Am. J. Physiol., 222, 399-403.
14. Greco, O., Dachs, G.U., Tozer, G.M. and Kanthou, C. (2002): Mechanisms of cytotoxicity induced by horseradish peroxidase/indole-3-acetic acid gene therapy. J. Cell Biochem., 87, 221-232.
15. Gressens, P. (2000): Mechanisms and disturbances of neuronal migration. Pediatr. Res., 48, 725-730.
16. Hoshino, K. and Kameyama, Y. (1988): Developmental-stage-dependent radiosensitivity of neural cells in the ventricular zone of telencephalon in mouse and rat fetuses. Teratology, 37, 257-262.
17. Ichimura, H. and Yamaki, T. (1975): Indole-3-acetic acid in animal embryos. Sci. Pap. Coll. Gen. Educ. Unive. Tokyo, 25, 43-48.
18. John, J.A., Blogg, C.D., Murray, F.J., Schwetz, B.A. and Gehring, P.J. (1979): Teratogenic effects of the plant hormone indole-3-acetic acid in mice and rats. Teratology, 19, 321-324.
19. Katayama, K., Ishigami, N., Suzuki, M., Ohtsuka, R., Kiatipattanasakul, W., Nakayama, H. and Doi, K. (2000a): Teratologic studies on rat perinates and offspring from dams treated with ethylnitrosourea (ENU). Exp. Anim., 49, 181-187.
20. Katayama, K., Ishigami, M., Uetsuka, K., Nakayama, H. and Doi, K. (2000b): Ethylnitrosourea (ENU)-induced apoptosis in the rat fetal tissues. Histol. Histopathol., 15, 707-711.
21. Kim, D.S., Jeon, S.E. and Park, K.C. (2004): Oxidation of indole-3-acetic acid by horseradish peroxidase induces apoptosis in G361 human melanoma cells. Cell Signal, 16, 81-88.
22. Liu, F. and Zhao, L.J. (2000): Antioxidative and free radical scavenging activities of pineal indoles Ng TB. Neural. Transm., 107, 1243-1251.
23. Lu, D.P., Nakayama, H., Shinozuka, J., Uetsuka, K., Taki, R. and Doi, K. (1998): 5-azacytidine-induced apoptosis in the central nervous system of developing rat fetuses. J. Toxicol. Pathol., 11, 133-136.
24. Mark, T.D. and David J.L. (2003): Calculation of physicochemical properties, In Predicting chemical toxicity and fate (Mark T.D.C. and David J.L., eds.), pp. 31-40. CRC Press, Baca Raton.
25. Miller, M.W. (1986): Effects of alcohol on the generation and migration of cerebral cortical neurons. Science, 233, 1308-1311.
26. Monnet-Tschudi, F. (1998): Induction of apoptosis by mercury compounds depends on maturation and is not associated with microglial activation. J. Neurosci. Res., 53, 361-367.
27. Nigovic, B., Antolic, S., Kojic-Prodic, B., Kiralj, R., Magnus, V. and Salopek-Sondi, B. (2000): Correlation of structural and physico-chemical parameters with the bioactivity of alkylated derivatives of indole-3-acetic acid, a phytohormone (auxin). Acta Crystallogr., B56, 94-111.
28. O'Leary, D.D.M. and Koester, S.E. (1993): Development of projection neuron types, axon pathways, and patterned connections of the mammalian cortex. Neuron, 10, 991-1006.
29. Rice, D. and Barone, S.J. (2000): Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models. Environ. Health Perspect., 108, 511-533.
30. Rossiter, S., Folkes, L.K. and Wardman, P. (2002): Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential for targeted cancer therapy. Bioorg. Med. Chem. Lett., 16, 2523-2526.
31. Sun, X.Z., Takahashi, S., Cui, C., Zhang, R., Sakata-Haga, H., Sawada, K. and Fukui, Y. (2002): Normal and abnormal neuronal migration in the developing cerebral cortex. J. Med. Invest., 49, 97-110.
32. Takai, H., Katayama, K., Yasohima, A., Uetsuka, K., Nakayama, H. and Doi, K. (2003): NMDA-induced apoptosis in the developing rat brain. Exp. Toxic. Pathol., 55, 33-37.
33. Tamaru, M. and Roberts, E. (1988): Structure-activity studies on inhibition of choline uptake by a mouse brain synaptosomal preparation: Basic data. Brain Res., 473, 205-226.
34. Ueno, M., Katayama, K., Nakayama, H. and Doi, K. (2002a): Mechanisms of 5-azacytidine (5Az-C)-induced toxicity in the rat brain. Int. J. Exp. Path., 83, 139-150.
35. Ueno, M., Katayama, K., Yasoshima, A., Nakayama, H. and Doi, K. (2002b): 5-Azacytidine (5AzC)-induced histopathological changes in the central nervous system of rat fetuses. Exp. Toxicol. Pathol., 54, 91-96.
36. Yamauchi, H., Katayama, K., Yasohima, A., Uetsuka, K., Nakayama, H. and Doi, K. (2003): 1-β-D-arabinofuranosylcytosine (Ara-C)-induced apoptosis in the rat fetal tissues and placenta. J. Toxicol. Pathol., 16, 223-229.