The true treatment benefit is unpredictable in clinical trials using surrogate outcome measured with diagnostic tests

Journal of Clinical Epidemiology

Volumn 58, Issue 10, 2005, Pages 1042-1051

  Kassaï, Behrouz ^a   Shah, Nirav R ^b   Leizorovicza, Alain ^a   Cucherat, Michel ^a   Gueyffier, Francois ^a   Boissel, Jean Pierre ^a  

^a HOSPICES CIVILS DE LYON   (France)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

Biologic markers; Clinical trials; Diagnosis; Sensitivity and specificity; Surrogate end points; Venous thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN;

CORRELATION ANALYSIS; DEEP VEIN THROMBOSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DIAGNOSTIC PROCEDURE; HIGH RISK POPULATION; HUMAN; MEDICAL RESEARCH; OUTCOMES RESEARCH; PHLEBOGRAPHY; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; STANDARD; TREATMENT OUTCOME; VENOUS THROMBOEMBOLISM;

EID: 24944433991     PISSN: 08954356     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jclinepi.2005.02.024     Document Type: Article

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