-
1
-
-
0023358977
-
Mutant sequences as probes of protein folding mechanisms
-
Matthews, C. R., and Hurle, M. R. (1987) Mutant sequences as probes of protein folding mechanisms, BioEssays 6, 254-257.
-
(1987)
BioEssays
, vol.6
, pp. 254-257
-
-
Matthews, C.R.1
Hurle, M.R.2
-
2
-
-
0024965449
-
Mutational analysis of a protein-folding pathway
-
Goldenberg, D. P., Frieden, R. W., Haack, J. A., and Morrision, T. B. (1989) Mutational analysis of a protein-folding pathway, Nature 338, 127-132.
-
(1989)
Nature
, vol.338
, pp. 127-132
-
-
Goldenberg, D.P.1
Frieden, R.W.2
Haack, J.A.3
Morrision, T.B.4
-
3
-
-
0024358426
-
Mapping the transition state and pathway of protein folding by protein engineering
-
Matouschek, A., Kellis, J. T., Serrano, L., and Fersht, A. R. (1989) Mapping the transition state and pathway of protein folding by protein engineering, Nature 340, 122-126.
-
(1989)
Nature
, vol.340
, pp. 122-126
-
-
Matouschek, A.1
Kellis, J.T.2
Serrano, L.3
Fersht, A.R.4
-
4
-
-
0027313673
-
Pathways of protein folding
-
Matthews, C. R. (1993) Pathways of protein folding, Annu. Rev. Biochem. 62, 653-683.
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 653-683
-
-
Matthews, C.R.1
-
5
-
-
0026579572
-
The folding of an enzyme. III. Structure of the transition state for unfolding of barnase analysed by a protein engineering method
-
Serrano, L., Matouschek, A., and Fersht, A. R. (1992) The folding of an enzyme. III. Structure of the transition state for unfolding of barnase analysed by a protein engineering method, J. Mol. Biol. 224, 805-818.
-
(1992)
J. Mol. Biol.
, vol.224
, pp. 805-818
-
-
Serrano, L.1
Matouschek, A.2
Fersht, A.R.3
-
6
-
-
0026563495
-
The folding of an enzyme. VI. The folding pathway of barnase: Comparison with theoretical models
-
Serrano, L., Matouschek, A., and Fersht, A. R. (1992) The folding of an enzyme. VI. The folding pathway of barnase: comparison with theoretical models, J. Mol. Biol. 224, 847-859.
-
(1992)
J. Mol. Biol.
, vol.224
, pp. 847-859
-
-
Serrano, L.1
Matouschek, A.2
Fersht, A.R.3
-
7
-
-
0028856785
-
Optimization of the folding rates of protein folding: The nucleation-condensation mechanism and its implication
-
Fersht, A. R. (1995) Optimization of the folding rates of protein folding: the nucleation-condensation mechanism and its implication, Proc. Natl. Acad. Sci. U.S.A. 92, 10869-10873.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 10869-10873
-
-
Fersht, A.R.1
-
8
-
-
0031043161
-
Nucleation mechanisms in protein folding
-
Fersht, A. R. (1997) Nucleation mechanisms in protein folding, Curr. Opin. Struct. Biol. 7, 3-9.
-
(1997)
Curr. Opin. Struct. Biol.
, vol.7
, pp. 3-9
-
-
Fersht, A.R.1
-
9
-
-
0036296248
-
Protein folding kinetics beyond the φ value: Using multiple amino acid substitutions to investigate the structure of the SH3 domain folding transition state
-
Northey, J. G. B., Maxwell, K. L., and Davidson, A. R. (2002) Protein folding kinetics beyond the φ value: using multiple amino acid substitutions to investigate the structure of the SH3 domain folding transition state, J. Mol. Biol. 320, 389-402.
-
(2002)
J. Mol. Biol.
, vol.320
, pp. 389-402
-
-
Northey, J.G.B.1
Maxwell, K.L.2
Davidson, A.R.3
-
10
-
-
0035970299
-
Dramatic stabilization of an SH3 domain by a single substitution: Roles of the folded and unfolded states
-
Mok, Y. K., Elisseeva, E. L., Davidson, A. R., and Forman-Kay, J. D. (2001) Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states, J. Mol. Biol. 307, 913-928.
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 913-928
-
-
Mok, Y.K.1
Elisseeva, E.L.2
Davidson, A.R.3
Forman-Kay, J.D.4
-
11
-
-
2542599277
-
Phi-value analysis and the nature of protein-folding transition states
-
Fersht, A. R., and Sato, S. (2004) Phi-value analysis and the nature of protein-folding transition states, Proc. Natl. Acad. Sci. U.S.A. 101, 7976-81.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 7976-7981
-
-
Fersht, A.R.1
Sato, S.2
-
12
-
-
0034872511
-
Transition states and the meaning of φ-values in protein folding kinetics
-
Ozkan, S. B., Bahar, I., and Dill, K. A. (2001) Transition states and the meaning of φ-values in protein folding kinetics, Nat. Struct. Biol. 8, 765-769.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 765-769
-
-
Ozkan, S.B.1
Bahar, I.2
Dill, K.A.3
-
13
-
-
0036266942
-
Conformational strain in the Hydrophobic core and its implications for protein folding and design
-
Ventura, S., Vega, M. C., Lacroix, E., Angrand, I., Spagnolo, L., and Serrano, L. (2002) Conformational strain in the Hydrophobic core and its implications for protein folding and design, Nat. Struct. Biol. 9, 485-493.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 485-493
-
-
Ventura, S.1
Vega, M.C.2
Lacroix, E.3
Angrand, I.4
Spagnolo, L.5
Serrano, L.6
-
14
-
-
0034112774
-
Kinetics, thermodynamics and the evolution of non-native interactions in a protein folding nucleus
-
Li, L., Mirny, L. A., and Shakhnovich, E. I. (2000) Kinetics, thermodynamics and the evolution of non-native interactions in a protein folding nucleus, Nat. Struct. Biol. 7, 336-342.
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 336-342
-
-
Li, L.1
Mirny, L.A.2
Shakhnovich, E.I.3
-
15
-
-
0345304461
-
Origin of unusual φ-values in protein folding: Evidence against specific nucleation sites
-
Sanchez, I. E., and Kiefhaber, T. (2003) Origin of unusual φ-values in protein folding: evidence against specific nucleation sites, J. Mol. Biol. 334, 1077-1085.
-
(2003)
J. Mol. Biol.
, vol.334
, pp. 1077-1085
-
-
Sanchez, I.E.1
Kiefhaber, T.2
-
16
-
-
3343013823
-
The analysis of protein folding kinetic data produced in protein engineering experiments
-
Zarrine-Afsar, A., and Davidson, A. R. (2004) The analysis of protein folding kinetic data produced in protein engineering experiments, Methods 34, 41-50.
-
(2004)
Methods
, vol.34
, pp. 41-50
-
-
Zarrine-Afsar, A.1
Davidson, A.R.2
-
17
-
-
11244328062
-
Protein folding in high-dimensional spaces: Hypergutters and the role of non-native interactions
-
McLeish, T. C. B. (2005) Protein folding in high-dimensional spaces: hypergutters and the role of non-native interactions. Biophys. J. 88, 172-183.
-
(2005)
Biophys. J.
, vol.88
, pp. 172-183
-
-
McLeish, T.C.B.1
-
18
-
-
0036836534
-
Non-native interactions, effective contact order, and protein folding: A mutational investigation with the energetically frustrated hydrophobic model
-
Treptow, W. L., Barbosa, M. A. A., Garcia, L. G., and Araujo, A. F. P. (2002) Non-native interactions, effective contact order, and protein folding: a mutational investigation with the energetically frustrated hydrophobic model, Proteins 49, 167-180.
-
(2002)
Proteins
, vol.49
, pp. 167-180
-
-
Treptow, W.L.1
Barbosa, M.A.A.2
Garcia, L.G.3
Araujo, A.F.P.4
-
19
-
-
0028868995
-
The structure of the transition state for folding of chymotrypsin inhibitor 2 analysed by protein engineering methods: Evidence for a nucleation-condensation mechanism for protein folding
-
Itzhaki, L. S., Otzen, D. E., and Fersht, A. R. (1995) The structure of the transition state for folding of chymotrypsin inhibitor 2 analysed by protein engineering methods: evidence for a nucleation-condensation mechanism for protein folding, J. Mol. Biol. 254, 260-288.
-
(1995)
J. Mol. Biol.
, vol.254
, pp. 260-288
-
-
Itzhaki, L.S.1
Otzen, D.E.2
Fersht, A.R.3
-
20
-
-
0032734515
-
Experiment and theory highlight role of native state topology in SH3-folding
-
Riddle, D. S., Grantcharova, V. P., Santiago, J. V., Alm, E., Ruczinski, I., and Baker, D. (1999) Experiment and theory highlight role of native state topology in SH3-folding, Nat. Struct. Biol. 6, 1016-1024.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 1016-1024
-
-
Riddle, D.S.1
Grantcharova, V.P.2
Santiago, J.V.3
Alm, E.4
Ruczinski, I.5
Baker, D.6
-
21
-
-
0037117477
-
Unspecific hydrophobic stabilization of folding transition states
-
Viguera, A. R., Vega, C., and Serrano, L. (2002) Unspecific hydrophobic stabilization of folding transition states, Proc. Natl. Acad. Sci. U.S.A 99, 5349-5354.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 5349-5354
-
-
Viguera, A.R.1
Vega, C.2
Serrano, L.3
-
22
-
-
0036172116
-
Hydrophobic core packing in the SH3 domain folding transition state
-
Northey, J. G., Di Nardo, A. A., and Davidson, A. R. (2002) Hydrophobic core packing in the SH3 domain folding transition state, Nat. Struct. Biol. 2, 126-130.
-
(2002)
Nat. Struct. Biol.
, vol.2
, pp. 126-130
-
-
Northey, J.G.1
Di Nardo, A.A.2
Davidson, A.R.3
-
23
-
-
0034984382
-
Mapping the folding pathway of an immunoglobulin domain: Structural detail from φ value analysis and movment of the transition state
-
Fowler, S. B., and Clarke, J. (2001) Mapping the folding pathway of an immunoglobulin domain: structural detail from φ value analysis and movment of the transition state, Structure 9, 355-366.
-
(2001)
Structure
, vol.9
, pp. 355-366
-
-
Fowler, S.B.1
Clarke, J.2
-
24
-
-
0034671177
-
The SH3-fold family: Experimental evidence and prediction of variations in the folding pathways
-
Guerois, R., and Serrano, L. (2000) The SH3-fold family: experimental evidence and prediction of variations in the folding pathways, J. Mol. Biol. 304, 967-982.
-
(2000)
J. Mol. Biol.
, vol.304
, pp. 967-982
-
-
Guerois, R.1
Serrano, L.2
-
25
-
-
0032750509
-
The folding transition state between SH3 domains is conformationally restricted and evolutionarily conserved
-
Martinez, J. C., and Serrano, L. (1999) The folding transition state between SH3 domains is conformationally restricted and evolutionarily conserved, Nat. Struct. Biol. 6, 1010-1016.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 1010-1016
-
-
Martinez, J.C.1
Serrano, L.2
-
26
-
-
0031853167
-
Important role of hydrogen bonds in the structurally polarized transition state for the folding of the Src SH3 domain
-
Grantcharova, V. P., Riddle, D. S., Santiago, J. V., and Baker, D. (1998) Important role of hydrogen bonds in the structurally polarized transition state for the folding of the Src SH3 domain, Nat. Struct. Biol. 5, 714-720.
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 714-720
-
-
Grantcharova, V.P.1
Riddle, D.S.2
Santiago, J.V.3
Baker, D.4
-
27
-
-
0036829967
-
Complete change of the protein folding transition state upon circular permutation
-
Linberg, M., Tangrot, J., and Oliveberg, M. (2002) Complete change of the protein folding transition state upon circular permutation, Nat. Struct. Biol. 9, 818-822.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 818-822
-
-
Linberg, M.1
Tangrot, J.2
Oliveberg, M.3
-
28
-
-
0036293485
-
Conformational plasticity in folding of the split β-α-β protein S6: Evidence for burst-phase disruption of the native state
-
Otzen, D. E., and Oliveberg, M. (2001) Conformational plasticity in folding of the split β-α-β protein S6: Evidence for burst-phase disruption of the native state, J. Mol. Biol. 317, 613-627.
-
(2001)
J. Mol. Biol.
, vol.317
, pp. 613-627
-
-
Otzen, D.E.1
Oliveberg, M.2
-
29
-
-
0034685619
-
A breakdown of symmetry in the folding transition state of protein L
-
Kim, D. E., Fisher, C., and Baker, D. (2000) A breakdown of symmetry in the folding transition state of protein L, J. Mol. Biol. 298, 971-984.
-
(2000)
J. Mol. Biol.
, vol.298
, pp. 971-984
-
-
Kim, D.E.1
Fisher, C.2
Baker, D.3
-
30
-
-
0033871567
-
Critical role of β-hairpin formation in protein G folding
-
McCallister, E. L., Alm, E., and Baker, D. (2000) Critical role of β-hairpin formation in protein G folding, Nat. Struct. Biol. 7, 669-673.
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 669-673
-
-
McCallister, E.L.1
Alm, E.2
Baker, D.3
-
31
-
-
0037423705
-
Structural analysis of the rate-limiting transition states in the folding of Im7 and Im9: Similarities and differences in the folding of homologous proteins
-
Friel, C. T., Capaldi, A. P., and Radford, S. E. (2003) Structural analysis of the rate-limiting transition states in the folding of Im7 and Im9: similarities and differences in the folding of homologous proteins, J. Mol. Biol. 326, 293-305.
-
(2003)
J. Mol. Biol.
, vol.326
, pp. 293-305
-
-
Friel, C.T.1
Capaldi, A.P.2
Radford, S.E.3
-
32
-
-
0035793212
-
The folding nucleus of fibronectin type III domain is composed of core residues of the immunoglobulin-like fold
-
Cota, E., Steward, A., Fowler, S. B., and Clarke, J. (2001) The folding nucleus of fibronectin type III domain is composed of core residues of the immunoglobulin-like fold, J. Mol. Biol. 305, 1185-1194.
-
(2001)
J. Mol. Biol.
, vol.305
, pp. 1185-1194
-
-
Cota, E.1
Steward, A.2
Fowler, S.B.3
Clarke, J.4
-
33
-
-
0032812796
-
Mapping the interactions present in the transition state for unfolding/folding of FKBP12
-
Fulton, K. F., Main, E. R. G., Daggett, V., and Jackson, S. E. (1999) Mapping the interactions present in the transition state for unfolding/folding of FKBP12, J. Mol. Biol. 291, 445-461.
-
(1999)
J. Mol. Biol.
, vol.291
, pp. 445-461
-
-
Fulton, K.F.1
Main, E.R.G.2
Daggett, V.3
Jackson, S.E.4
-
34
-
-
0034677663
-
The folding of an immunoglobulin-like greek key protein is defined by a common-core nucleus and regions constrained by topology
-
Hamill, S. J., Steward, A., and Clarke, J. (2000) The folding of an immunoglobulin-like greek key protein is defined by a common-core nucleus and regions constrained by topology, J. Mol. Biol. 297, 165-178.
-
(2000)
J. Mol. Biol.
, vol.297
, pp. 165-178
-
-
Hamill, S.J.1
Steward, A.2
Clarke, J.3
-
35
-
-
0032708771
-
Mutational analysis of acylphosphates suggests the importance of topology and contact order in protein folding
-
Chiti, F., Taddei, N., White, P. M., Bucciantini, M., Magherini, F., Stefani, M., and Dobson, C. M. (1999) Mutational analysis of acylphosphates suggests the importance of topology and contact order in protein folding, Nat. Struct. Biol. 6, 1005-1009.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 1005-1009
-
-
Chiti, F.1
Taddei, N.2
White, P.M.3
Bucciantini, M.4
Magherini, F.5
Stefani, M.6
Dobson, C.M.7
-
36
-
-
0033015989
-
The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP
-
Kragelund, B. B., Osmark, P., Neergaard, T. B., Schiodt, J., Kristiansen, K., Knudsen, J., and Poulsen, F. M. (1999) The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP, Nat. Struct. Biol. 6, 594-601.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 594-601
-
-
Kragelund, B.B.1
Osmark, P.2
Neergaard, T.B.3
Schiodt, J.4
Kristiansen, K.5
Knudsen, J.6
Poulsen, F.M.7
-
37
-
-
0032515105
-
Structure of the transition state in the folding process of human procarboxypeptidase a2 activation domain
-
Villegas, V., Martinez, J. C., Aviles, F. X., and Serrano, L. (1998) Structure of the transition state in the folding process of human procarboxypeptidase a2 activation domain, J. Mol. Biol. 283, 1027-1036.
-
(1998)
J. Mol. Biol.
, vol.283
, pp. 1027-1036
-
-
Villegas, V.1
Martinez, J.C.2
Aviles, F.X.3
Serrano, L.4
-
38
-
-
5144225084
-
Relationship of Leffler (Brønsted) α values and protein folding φ values to position of transition-state structures on reaction coordinates
-
Fersht, A. R. (2004) Relationship of Leffler (Brønsted) α values and protein folding φ values to position of transition-state structures on reaction coordinates, Proc. Natl. Acad. Sci. U.S.A 101, 14338-14342.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 14338-14342
-
-
Fersht, A.R.1
-
39
-
-
20044363782
-
Protein folding: Defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins
-
Maxwell, K. L., Wildes, D., Zarrine-Afsar, A., De Los Rios, M. A., Brown, A. G., Friel, C. T., Hedberg, L., Horng, J. C., Bona, D., Miller, E. J., Vallee-Belisle, A., Main, E. R., Bemporad, F., Qiu, L., Teilum, K., Vu, N. D., Edwards, A. M., Ruczinski, I., Poulsen, F. M., Kragelund, B. B., Michnick, S. W., Chiti, F., Bai, Y., Hagen, S. J., Serrano, L., Oliveberg, M., Raleigh, D. P., Wittung-Stafshede, P., Radford, S. E., Jackson, S. E., Sosnick, T. R., Marqusee, S., Davidson, A. R., and Plaxco, K. W. (2005) Protein folding: Defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins, Protein Sci. 14, 602-616.
-
(2005)
Protein Sci.
, vol.14
, pp. 602-616
-
-
Maxwell, K.L.1
Wildes, D.2
Zarrine-Afsar, A.3
De Los Rios, M.A.4
Brown, A.G.5
Friel, C.T.6
Hedberg, L.7
Horng, J.C.8
Bona, D.9
Miller, E.J.10
Vallee-Belisle, A.11
Main, E.R.12
Bemporad, F.13
Qiu, L.14
Teilum, K.15
Vu, N.D.16
Edwards, A.M.17
Ruczinski, I.18
Poulsen, F.M.19
Kragelund, B.B.20
Michnick, S.W.21
Chiti, F.22
Bai, Y.23
Hagen, S.J.24
Serrano, L.25
Oliveberg, M.26
Raleigh, D.P.27
Wittung-Stafshede, P.28
Radford, S.E.29
Jackson, S.E.30
Sosnick, T.R.31
Marqusee, S.32
Davidson, A.R.33
Plaxco, K.W.34
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