Low level exposure to chemicals and immune system

Toxicology and Applied Pharmacology

Volumn 207, Issue 2 SUPPL., 2005, Pages 320-328

  Colosio, C ^a   Birindelli, S ^a   Corsini, E ^b   Galli, C L ^b   Maroni, M ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Immune system; Immunotoxicity; Pesticides; Tier approach

Indexed keywords

PESTICIDE;

CHEMICAL ENVIRONMENT; COMPARATIVE STUDY; CONFERENCE PAPER; DRUG EXPOSURE; ENVIRONMENTAL EXPOSURE; GENETIC HETEROGENEITY; HUMAN; IMMUNE SYSTEM; IMMUNOMODULATION; IMMUNOPATHOLOGY; IMMUNOTOXICITY; LONGITUDINAL STUDY; NONHUMAN; OCCUPATIONAL HEALTH; OCCUPATIONAL TOXICOLOGY; PHYSICIAN; RISK FACTOR; WORK ENVIRONMENT;

EID: 24644487872     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.01.025     Document Type: Conference Paper

References (89)

1. F. Andre, J. Gillon, C. Andre, S. Lafont, and G. Jourdan Pesticide-containing diets augment anti-sheep red blood cell nonreaginic antibody responses in mice but may prolong murine infection with Giardia muris Environ. Res. 32 1983 145 150
2. G. Arlaud, M. Colomb, and J. Gagnon A functional model of the human C1 complex Immunol. Today 8 1987 106
3. N. Auphan, J.A. Di Donato, C. Rosette, A. Helmberg, and M. Karin Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis Science 270 1995 232 233 (Comment in)
4. J.B. Barnett, and J. Gandy Effect of acute propanil exposure on the immune response of C57Bl/6 mice Fundam. Appl. Toxicol. 12 1989 757 764
5. J.B. Barnett, and K.E. Rodgers Pesticides J.H. Dean M.I. Luster A.E. Munson I. Kimber Immunotoxicology and Immunopharmacology 2nd edition 1994 Raven Press New York 191 212
6. E.L. Becker Phosphonate inhibition of the accumulation and retention of K+ by rabbit neutrophils in relation to chemotaxis J. Immunol. 106 1971 689 697
7. J. Bernier, P. Hugo, K. Krzystyniak, and M. Fournier Suppression of humoral immunity in inbred mice by dieldrin Toxicol. Lett. 35 1987 231 240
8. J. Bernier, D. Girard, K. Krzystyniak, G. Chevalier, B. Trottier, D. Nadeau, M. Rola-Pleszczynski, and M. Fournier Immunotoxicity of aminocarb: III. Exposure route-dependent immunomodulation by aminocarb in mice Toxicology 5 1995 135 146
9. B.R. Blakley, M.J. Yole, P. Brousseau, H. Boermans, and M. Fournier Effect of chlorpyrifos on immune function in rats Vet. Hum. Toxicol. 41 1999 140 144
10. G. Blyler, K.S. Landreth, T. Lillis, R. Schafer, S.A. Theus, J. Gandy, and J.B. Barnett Selective myelotoxicity of propanil Fundam. Appl. Toxicol. 22 1994 505 510
11. P.A. Botham Are pesticides immunotoxic? Adverse Drug React. Acute Poisoning Rev. 9 1990 91 101 (Summer)
12. P.G. Burney, S. Chinn, and R.J. Rana Has the prevalence of asthma increased in children? Evidence from the national study of health and growth 1973-86 Br. Med. J. 300 1990 1306 1310
13. M.L. Burr, B.K. Butland, S. King, and E. Vaugham Williams Changes in asthma prevalence: two surveys 15 years apart Arch. Dis. Child. 64 1989 1452 1456
14. Cancer Mondial. http://www-dep.iarc.fr.
15. G.P. Casale, S.D. Cohen, and R.A. Di Capua The effects of organophosphate-induced cholinergic stimulation on the antibody response to sheep erythrocytes in inbred mice Toxicol. Appl. Pharmacol. 68 1983 198 205
16. G. Chodorowska, D. Czelej, and M. Niewiedziol Activity of Tumor Necrosis Factor-alpha (TNF-alpha) and its soluble type I receptor (p55TNF-R) in some drug-induced cutaneous reactions Ann. Univ. Mariae Curie-Sklodowska [Med] 58 2003 50 56
17. C. Colosio, M. Tomasini, S. Cairoli, V. Foa', M. Marinovich, and C.L. Galli Occupational triphenyltin acetate poisoning: a case report Br. J. Ind. Med. 48 1990 136 139
18. C. Colosio, M. Maroni, and W. Barcellini Toxicological and immune findings in workers exposed to pentachlorophenol (PCP) Arch. Environ. Health 48 1993 81 88
19. C. Colosio, W. Barcellini, M. Maroni, D. Alcini, M. Bersani, D. Cavallo, A. Galli, P.L. Meroni, R. Pastorelli, G.P. Rizzardi, L. Soleo, and V. Foà Immunomodulatory effects of occupational exposure to mancozeb Arch. Environ. Health 51 1996 445 451
20. V. Daniel, W. Huber, K. Bauer, and G. Opelz Impaired in-vitro lymphocyte responses in patients with elevated pentachlorophenol (PCP) blood levels Arch. Environ. Health 50 1995 287 292
21. J. Descotes Importance of immunotoxicity in safety assessment: a medical toxicologist's perspective Toxicol. Lett. 149 2004 103 108
22. A. Faustini, L. Settimi, R. Pacifici, V. Fano, P. Zuccaro, and F. Forastiere Immunological changes among farmers exposed to phenoxy herbicides: preliminary observations Occup. Environ. Med. 53 1996 583 585
23. M.C. Fiore, H.A. Anderson, R. Hong, R. Gilubjatnokov, J.E. Seiser, D. Nordstrom, L. Hanrahan, and D. Belluk Chronic exposure to aldicarb-contaminated groundwater and human immune function Environ. Res. 41 1986 633 645
24. L.L. Frost, Y.X. Neeley, R. Schafer, L.F. Gibson, and J.B. Barnett Propanil inhibits tumor necrosis factor-alpha production by reducing nuclear levels of the transcription factor nuclear factor-kappab in the macrophage cell line ic-21 Toxicol. Appl. Pharmacol. 172 2001 186 193
25. V.F. Garry, J.T. Kelly, J.M. Sprafka, S. Edwards, and J. Griffith Survey of health and use characterization of pesticide appliers in Minnesota Arch. Environ. Health 49 1994 337 343
26. R.D. Handy, Abd-E.l., H.A. Samei, M.F. Bayomy, A.M. Mahran, A.M. Abdeen, and E.A. El-Elaimy Chronic diazinon exposure: pathologies of spleen, thymus, blood cells, and lymph nodes are modulated by dietary protein or lipid in the mouse Toxicology 5 2002 13 34
27. A. Hermanowicz, and S. Kossman Neutrophil function and infectious disease in workers occupationally exposed to phosphoorganic pesticides: role of mononuclear-derived chemotactic factor for neutrophils Clin. Immunol. Immunopathol. 33 1984 13 22
28. A. Hermanowicz, Z. Nawarska, D. Borys, and A. Maslankiewicz The neutrophil function and infectious diseases in workers exposed to organochlorine insecticides Int. Arch. Occup. Environ. Health 50 1982 329 340
29. D. Hudig, D. Redelman, and L.L. Minning The requirement for proteinase activity for human lymphocyte-mediated natural cytotoxicity (NK): evidence that the proteinase is serine dependent and has aromatic amino acid specificity of cleavage J. Immunol. 133 1984 2647 2654
30. International Programme on Chemical Safety (IPCS) Principles and methods for assessing directs immunotoxicity associated with exposure to chemicals Environmental Health Criteria vol. 180 1996 World Health Organization
31. D.L. Jacobson, S.J. Gange, N.R. Rose, and N.M. Graham Epidemiology and estimated population burden of selected autoimmune diseases in the United States Clin. Immunol. Immunopathol. 84 1997 223 243
32. S.K. Kashiap Health surveillance and biological monitoring of pesticide formulation in India Toxicol. Lett. 33 1986 107 114
33. S.A. Khan, and S.A. Ali Assessment of certain hematological responses of factory workers exposed to pesticides Bull. Environ. Contam. Toxicol. 51 1993 740 747
34. H.W. Klemmer, L. Wong, M.M. Sato, E.L. Reichert, R.J. Korsak, and M.N. Rashad Clinical finding in workers exposed to pentachlorophenol Arch. Environ. Contam. Toxicol. 9 1980 715 725
35. G.S. Ladics, C. Smith, K. Heaps, and S.E. Loveless Evaluation of the humoral immune response of CD rats following a 2-week exposure to the pesticide carbaryl by the oral, dermal, or inhalation routes J. Toxicol. Environ. Health 42 1994 143 156
36. G. Lavie, Z. Leib, and C. Servadio The mechanism of human NK cell-mediated cytotoxicity. Mode of action of surface-associated proteases in the early stages of the lytic reaction J. Immunol. 135 1985 1470 1476
37. E. Lemarie, M. Musset, C. Charbonnier, M. Renoux, and G. Renoux Clinical characterization of imuthiol Methods Find. Exp. Clin. Pharmacol. 8 1986 51 54
38. Q. Li, Y. Hirata, S. Piao, and M. Minami The by-products generated during sarin synthesis in the Tokyo sarin disaster induced inhibition of natural killer and cytotoxic T lymphocyte activity Toxicology 5 2000 209 220
39. M.I. Luster, and G.J. Rosenthal Chemical agents and the immune response Environ. Health Perspect. 100 1993 219 226
40. M.I. Luster, A.E. Munson, P.T. Thomas, M.P. Holsapple, J.D. Fenters, K.L. White Jr., L.D. Lauer, D.R. Germolec, G.J. Rosenthal, and J.H. Dean Development of a testing battery to assess chemical-induced immunotoxicity: National Toxicology Program's guidelines for immunotoxicity evaluation in mice Fundam. Appl. Toxicol. 10 1988 2 19
41. M.I. Luster, D.G. Pait, C. Portier, G.J. Rosenthal, D.R. Germolec, C.E. Comment, A.E. Munson, K. White, and P. Pollock Qualitative and quantitative experimental models to aid in risk assessment for immunotoxicology Toxicol. Lett. 71-78 1992 64 65
42. M.I. Luster, C. Portier, D.G. Pait, K.L. White, C. Gennings, A.E. Munson, and G.J. Rosenthal Risk assessment in immunotoxicology. I. Sensitivity and predictability of immune tests Fundam. Appl. Toxicol. 18 1992 200 210
43. P.R. McConnachie, and A.C. Zahlsky Immunological consequences of exposure to pentachlorophenol Arch. Environ. Health 46 1991 249 253
44. P.R. McConnachie, and A.C. Zahalsky Immune alterations in humans exposed to the termiticide technical chlordane Arch. Environ. Health 47 1992 295 301
45. P. Meera, P.R. Rao, R. Shanker, and O. Tripathi Immunomodulatory effects of gamma-HCH (Lindane) in mice Immunopharmacol. Immunotoxicol. 14 1992 261 282
46. S. Menconi, J.M. Clark, P. Langenberg, and D. Hryhorczuk A preliminary study of potential human effects in private residences following chlordane applications for termite control Arch. Environ. Health 43 1988 349 352
47. C.C. Michielsen, H. van Loveren, and J.G. Vos The role of the immune system in hexachlorobenzene-induced toxicity Environ. Health Perspect. 107 Suppl. 5 1999 783 792
48. T.H. Milby, and W.L. Epstein Allergic contact sensitivity to malathion Arch. Environ. Health 22 1964 434 437
49. I.R. Mirkin, H.A. Anderson, L. Handaran, R. Hong, R. Gilubjatnikov, and D. Belluk Changes in T-lymphocytes distribution associated with ingestion of aldicarb-contaminated drinking water: a follow-up study Environ. Res. 51 1990 35 50
50. R.A. Musson, and E.L. Becker The role of an activatable esterase in immune-dependent phagocytosis by human neutrophils J. Immunol. 118 1977 1354 1365
51. Organisation for Economic Co-operation and Development, 1981. OECD guidelines for testing chemicals: repeated dose oral toxicity-Rodent: 28 day or 14 day study (Guideline 407). Paris.
52. S. Orrenius, C.S. Nobel, D.J. van den Dobbelsteen, M.J. Burkitt, and A.F. Slater Dithiocarbamates and the redox regulation of cell death Biochem. Soc. Trans. 24 1996 1032 1038
53. M.R. Prater, R.M. Gogal Jr., B.L. Blaylock, J. Longstreth, and S.D. Holladay Single-dose topical exposure to the pyrethroid insecticide, permethrin in C57BL/6N mice: effects on thymus and spleen Food Chem. Toxicol. 40 2002 1863 1873
54. D.W. Pyatt, Y. Yang, B. Mehos, A. Le, W. Stillman, and R.D. Irons Hematotoxicity of the Chinese herbal medicine Tripterygium wilfordii hook f in CD34-positive human bone marrow cells Mol. Pharmacol. 57 2000 512 518
55. M.L. Queiroz, C. Bincoletto, R.C. Perlingeiro, M.R. Quadros, and C.A. Souza Immunoglobulin levels in workers exposed to hexachlorobenzene Hum. Exp. Toxicol. 17 1998 172 175
56. M.L. Queiroz, M.R. Quadros, M.C. Valadares, and J.P. Silveira Polymorphonuclear phagocytosis and killing in workers occupationally exposed to hexachlorobenzene Immunopharmacol. Immunotoxicol. 20 1998 447 454
57. M.L. Queiroz, M.D. Fernandes, and M.C. Valadares Neutrophil function in workers exposed to organophosphate and carbamate insecticides Int. J. Immunopharmacol. 21 1999 263 270
58. G. Renoux, M. Renoux, and J.M. Guillaumin Short communication: immunopharmacology and immunotoxicity of zinc diethyldithiocarbammate Int. J. Immunopharmacol. 4 1988 489 493
59. H.B. Richter-Reichhelm, R. Stahlmann, E. Smithi, and H. van Loveren Approaches to risk assessment of immunotoxic effects of chemicals Toxicology 161 2001 213 228
60. K.E. Rodgers, and D.D. Ellefson Modulation of macrophage protease activity by acute administration of O,O,S trimethyl phosphorothioate Agents Actions 29 1990 277 285
61. K. Rodgers, and S. Xiong Contributions of inflammatory mast cell mediators to alterations in macrophage function after malathion administration Int. J. Immunopharmacol. 19 1997 149 156
62. K. Rodgers, and S. Xiong Effect of administration of malathion for 90 days on macrophage function and mast cell degranulation Toxicol. Lett. 19 1997 73 82
63. K. Rodgers, and S. Xiong Effect of administration of malathion for 14 days on macrophage function and mast cell degranulation Fundam. Appl. Toxicol. 37 1997 95 99
64. K. Rodgers, and S. Xiong Effect of acute administration of malathion by oral and dermal routes on serum histamine levels Int. J. Immunopharmacol. 19 1997 437 441
65. K.E. Rodgers, T. Imamura, and B.H. Devens Effects of subchronic treatment with O,O,S-trimethyl phosphorothioate on cellular and humoral immune response systems Toxicol. Appl. Pharmacol. 81 1985 310 318
66. G. Santoni, F. Cantalamessa, L. Mazzucca, S. Romagnoli, and M. Piccoli Prenatal exposure to cypermethrin modulates rat NK cell cytotoxic functions Toxicology 120 1997 231 242
67. G. Santoni, F. Cantalamessa, R. Lavagna, S. Romagnoli, E. Spreghino, and M. Piccoli Cypermethrin-induced alteration of thymocyte distribution and functions in prenatally-exposed rats Toxicology 125 1998 67 78
68. P. Saval, G. Fugisang, C. Madsen, and O. Østerballe Prevalence of atopic diseases in Danish schoolchildren J. Pediatr. Allergy Immunol. 4 1993 117 122
69. R.I. Scheinman, P.C. Cogswell, A.K. Lofquist, and A.S. Baldwin Jr. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids Science 270 1995 283 286 Comment on
70. P. Schielen, A. Van Der Pijl, R. Bleumink, R.H. Pieters, and W. Seinen Local popliteal lymph node reactions to hexachlorobenzene and pentachlorobenzene: comparison with systemic effects Immunopharmacology 31 1996 171 181
71. P. Scuderi Suppression of human leukocyte tumor necrosis factor secretion by the serine protease inhibitor p-toluenesulfonyl-l-arginine methyl ester (TAME) J. Immunol. 143 1989 168 173
72. R.D. Sijoblad Potential future requirements for immunotoxicity testing of pesticides Toxicol. Ind. Health 4 1988 391 394
73. M. Tarkowski, W. Lutz, and S. Birindelli The lymphocytic cholinergic system and its modulation by organophosphorus pesticides Int. J. Occup. Med. Environ. Health 17 2004 325 337
74. Termorshuizen, F., Sleijffers, A., van den Hof, S., de Melker, H., Garssen, J., Boland, G.J., van Hattum, I., de Grujl, F.R., van Loveren, H., 2003. Chapter 5: Vaccine-induced antibody responses in relation to season. An analysis on hepatitis B, rubella and measles. Observational and epidemiological studies on the effects of solar ultraviolet radiation on immunity and infections. In: Fabian Termorshuizen (Ed.), Thesis University of Maastricht. Printed by: Print Partners Ipskamp, Enschede. ISBN: 90-9017571-7.
75. S.A. Theus, D.R. Tabor, J. Gandy, and J.B. Barnett Alteration of macrophage cytotoxicity through endogenous interferon and tumor necrosis factor alpha induction by propanil Toxicol. Appl. Pharmacol. 118 1993 46 52
76. J.D. Thrasher, R. Madison, and A. Broughton Immunological abnormalities in humans exposed to Chlorpyrifos: preliminary observations Arch. Environ. Health 48 1993 89 93
77. T. Tsvetkova, S. Andonova, E. Zvetkova, and S. Blagoeva Aspects of granulocyte function in workers professionally exposed to pesticides Int. Arch. Occup. Environ. Health 64 1992 275 279
78. US National Research Council Biologic markers in immunotoxicology 1992 National Academy Press Washington DC
79. N. Utsunomiya, and M. Nakanishi A serine protease triggers the initial step of transmembrane signalling in cytotoxic T cells J. Biol. Chem. 15 1986 16514 16517
80. G.L. Vanham, L. Kestens, J. Van Hoof, G. Penne, R. Colebunders, C. Goilav, M. Vandenbruaene, R. El Habib, and P. Gigase Immunological parameters during treatment with ditiocarb (Imuthiol) AIDS 7 1993 525 530
81. H. Van Loveren, and J.C. Vos Evaluation of OECD Guideline No 407 for assessment of toxicity of chemicals with respect to potential adverse effects to the immune system RIVM Rep. 1992 158801001
82. M.F. Vine, L. Stein, K. Weigle, J. Schroeder, D. Degnan, C.K. Tse, C. Hanchette, and L. Backer Effects on the immune system associated with living near a pesticide dump site Environ. Health Perspect. 108 2000 1113 11124
83. E. Von Mutius, F.D. Martinez, C. Fritzsch, H. Duhme, and U. Keil Skin test reactivity an number of siblings Br. Med. J. 308 1994 692 695
84. J.G. Vos, and H. Van Loveren Immunotoxicity testing in the rat. Advances in modern environmental toxicology E.J. Burger R.G. Tardiff J.A. Bellanti Environmental Chemical Exposures and Immune System Integrity vol. 13 1987 Princeton Scientific Publishing Princeton, NJ 167 180
85. R.L. Wong, J.K. Gutowski, M. Katz, R.H. Goldfarb, and S. Cohen Induction of DNA synthesis in isolated nuclei by cytoplasmic factors: inhibition by protease inhibitors Proc. Natl. Acad. Sci. U.S.A. 84 1987 241 245
86. Y.C. Xie, R. Schafer, and J.B. Barnett The immunomodulatory effects of the herbicide propanil on murine macrophage interleukin-6 and tumor necrosis factor-alpha production Toxicol. Appl. Pharmacol. 145 1997 184 191
87. J.D. Young, and Z.A. Cohn Cell-mediated killing: a common mechanism? Cell 46 1986 641 642
88. W. Zhao, R. Schafer, and J.B. Barnett Cytokine production by C57BL/6 mouse spleen cells is selectively reduced by exposure to propanil J. Toxicol. Environ. Health, A 25 1998 107 120
89. H.W. Ziegler-Heitbrock, T. Sternsdorf, J. Liese, B. Belohradsky, C. Weber, A. Wedel, R. Schreck, P. Bauerle, and M. Strobel Pyrrolidine dithiocarbamate inhibits NF-kappa B mobilization and TNF production in human monocytes J. Immunol. 15 1993 6893 6986