-
1
-
-
0028019880
-
Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: Implications for treatment with fluorouracil
-
Peters GJ, van der Wilt CL, van Groeningen CJ, Smid K, Meijer S and Pinedo HM: Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil. J Clin Oncol 12: 2035-2042, 1994. (Pubitemid 24356018)
-
(1994)
Journal of Clinical Oncology
, vol.12
, Issue.10
, pp. 2035-2042
-
-
Peters, G.J.1
Van Der, W.C.L.2
Van Groeningen, C.J.3
Smid, K.4
Meijer, S.5
Pinedo, H.M.6
-
2
-
-
0028151449
-
The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
-
Johnston PG, Fisher ER, Rockette HE, Fisher B, Wolmark N, Drake JC, et al: The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 12: 2640-2647, 1994. (Pubitemid 24379651)
-
(1994)
Journal of Clinical Oncology
, vol.12
, Issue.12
, pp. 2640-2647
-
-
Johnston, P.G.1
Fisher, E.R.2
Rockette, H.E.3
Fisher, B.4
Wolmark, N.5
Drake, J.C.6
Chabner, B.A.7
Allegra, C.J.8
-
3
-
-
14444285483
-
p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: An analysis of response and survival
-
Lenz HJ, Hayashi K, Salonga D, Danenberg KD, Danenberg PV, Metzger R, et al: p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival. Clin Cancer Res 4: 1243-1250, 1998. (Pubitemid 28213336)
-
(1998)
Clinical Cancer Research
, vol.4
, Issue.5
, pp. 1243-1250
-
-
Lenz, H.-J.1
Hayashi, K.2
Salonga, D.3
Danenberg, K.D.4
Danenberg, P.V.5
Metzger, R.6
Banerjee, D.7
Bertino, J.R.8
Groshen, S.9
Leichman, L.P.10
Leichman, C.G.11
-
4
-
-
15444349773
-
p53 and thymidylate synthase expression in untreated stage II colon cancer: Associations with recurrence, survival, and site
-
Lenz HJ, Danenberg KD, Leichman CG, Florentine B, Johnston PG, Groshen S, et al: p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site. Clin Cancer Res 4: 1227-1234, 1998. (Pubitemid 28213334)
-
(1998)
Clinical Cancer Research
, vol.4
, Issue.5
, pp. 1227-1234
-
-
Lenz, H.-J.1
Danenberg, K.D.2
Leichman, C.G.3
Florentine, B.4
Johnston, P.G.5
Groshen, S.6
Zhou, L.7
Xiong, Y.P.8
Danenberg, P.V.9
Leichman, L.P.10
-
5
-
-
0031941249
-
A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance
-
DOI 10.1002/(SICI)1097-0142(19980101)82:1<70::AID
-
Yamachika T, Nakanishi H, Inada K, Tsukamoto T, Kato T, Fukushima M, et al: A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance. Cancer 82: 70-77, 1998. (Pubitemid 28070481)
-
(1998)
Cancer
, vol.82
, Issue.1
, pp. 70-77
-
-
Yamachika, T.1
Nakanishi, H.2
Inada, K.-I.3
Tsukamoto, T.4
Kato, T.5
Fukushima, M.6
Inoue, M.7
Tatematsu, M.8
-
6
-
-
0034087575
-
Thymidylate synthase expression: An independent prognostic factor for local recurrence, distant metastasis, disease-free and overall survival in rectal cancer
-
Edler D, Hallstrom M, Johnston PG, Magnusson I, Ragnhammar P and Blomgren H: Thymidylate synthase expression: an independent prognostic factor for local recurrence, distant metastasis, disease-free and overall survival in rectal cancer. Clin Cancer Res 6: 1378-1384, 2000. (Pubitemid 30226223)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.4
, pp. 1378-1384
-
-
Edler, D.1
Hallstrom, M.2
Johnston, P.G.3
Magnusson, I.4
Ragnhammar, P.5
Blomgren, H.6
-
7
-
-
0028940399
-
Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston PG, Lenz HJ, Leichman CG, Danenberg KD, Allegra CJ, Danenberg PV, et al: Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 55: 1407-1412, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1407-1412
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
Danenberg, K.D.4
Allegra, C.J.5
Danenberg, P.V.6
-
8
-
-
0029095796
-
Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial
-
Leichman L, Lenz HJ, Leichman CG, Groshen S, Danenberg K, Baranda J, et al: Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: preliminary report from an ongoing trial. Eur J Cancer 31A: 1306-1310, 1995.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 1306-1310
-
-
Leichman, L.1
Lenz, H.J.2
Leichman, C.G.3
Groshen, S.4
Danenberg, K.5
Baranda, J.6
-
9
-
-
0037316169
-
Thymidylate synthase expression in hepatic tumors is a predictor of survival and progression in patients with resectable metastatic colorectal cancer
-
DOI 10.1200/JCO.2003.06.060
-
Gonen M, Hummer A, Zervoudakis A, Sullivan D, Fong Y, Banerjee D, et al: Thymidylate synthase expression in hepatic tumors is a predictor of survival and progression in patients with resectable metastatic colorectal cancer. J Clin Oncol 21: 406-412, 2003. (Pubitemid 46606467)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.3
, pp. 406-412
-
-
Gonen, M.1
Hummer, A.2
Zervoudakis, A.3
Sullivan, D.4
Fong, Y.5
Banerjee, D.6
Klimstra, D.7
Cordon-Cardo, C.8
Bertino, J.9
Kemeny, N.10
-
10
-
-
0032950876
-
Immunohistochemical detection of thymidylate synthase in advanced gastric cancer: A prognostic indicator in patients undergoing gastrectomy followed by adjuvant chemotherapy with 5-fluoropyrimidines
-
Suda Y, Kuwashima Y, Tanaka Y, Uchida K and Akazawa S: Immunohistochemical detection of thymidylate synthase in advanced gastric cancer: a prognostic indicator in patients undergoing gastrectomy followed by adjuvant chemotherapy with 5-fluoropyrimidines. Anticancer Res 19: 805-810, 1999. (Pubitemid 29168335)
-
(1999)
Anticancer Research
, vol.19
, Issue.1 B
, pp. 805-810
-
-
Suda, Y.1
Kuwashima, Y.2
Tanaka, Y.3
Uchida, K.4
Akazawa, S.5
-
11
-
-
0033035738
-
Enhanced expression of thymidylate synthase may be of prognostic importance in advanced cervical cancer
-
Suzuki M, Tsukagoshi S, Saga Y, Ohwada M and Sato I: Enhanced expression of thymidylate synthase may be of prognostic importance in advanced cervical cancer. Oncology 57: 50-54, 1999.
-
(1999)
Oncology
, vol.57
, pp. 50-54
-
-
Suzuki, M.1
Tsukagoshi, S.2
Saga, Y.3
Ohwada, M.4
Sato, I.5
-
12
-
-
0036924417
-
Irinotecan combined with bolus 5-fluorouracil and folinic acid Nordic schedule as first-line therapy in advanced colorectal cancer
-
DOI 10.1093/annonc/mdf324
-
Glimelius B, Ristamaki R, Kjaer M, Pfeiffer P, Toren JS, Tveit KM, et al: Irinotecan combined with bolus 5-fluorouracil and folinic acid Nordic schedule as first line therapy in advanced colorectal cancer. Ann Oncol 13: 1868-1873, 2002. (Pubitemid 36040775)
-
(2002)
Annals of Oncology
, vol.13
, Issue.12
, pp. 1868-1873
-
-
Glimelius, B.1
Ristamaki, R.2
Kjaer, M.3
Pfeiffer, P.4
Skovsgaard, T.5
Tveit, K.M.6
Linne, T.7
Frodin, J.E.8
Boussard, B.9
Oulid-Aissa, D.10
Pyrhonen, S.11
-
13
-
-
0019365237
-
Reporting results of cancer treatment
-
DOI 10.1002/1097-0142(19810101)47:1<207::AID
-
Miller AB, Hoogstraten B, Staquet M and Winkler A: Reporting results of cancer treatment. Cancer 47: 207-214, 1981. (Pubitemid 11167383)
-
(1981)
Cancer
, vol.47
, Issue.1
, pp. 207-214
-
-
Miller, A.B.1
Hoogstraten, B.2
Staquet, M.3
Winkler, A.4
-
14
-
-
0033833813
-
Progress in colorectal cancer chemotherapy: How far have we come, how far to go?
-
Royce ME, Hoff PM and Pazdur R: Progress in colorectal cancer chemotherapy: how far have we come, how far to go? Drugs Aging 17: 201-216, 2000.
-
(2000)
Drugs Aging
, vol.17
, pp. 201-216
-
-
Royce, M.E.1
Hoff, P.M.2
Pazdur, R.3
-
15
-
-
0034994538
-
Conventional cytotoxic and novel therapeutic concepts in colorectal cancer
-
DOI 10.1517/13543784.10.6.1011
-
Midgley R and Kerr D: Conventional cytotoxic and novel therapeutic concepts in colorectal cancer. Expert Opin Investig Drugs 10: 1011-1019, 2001. (Pubitemid 32519681)
-
(2001)
Expert Opinion on Investigational Drugs
, vol.10
, Issue.6
, pp. 1011-1019
-
-
Midgley, R.1
Kerr, D.2
-
16
-
-
0032585232
-
Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer
-
DOI 10.1016/S0140-6736(98)02309-5
-
Cunningham D, Pyrhonen S, James RD, Punt CJ, Hickish TF, Heikkila R, et al: Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer. Lancet 352: 1413-1418, 1998. (Pubitemid 28510874)
-
(1998)
Lancet
, vol.352
, Issue.9138
, pp. 1413-1418
-
-
Cunningham, D.1
Pyrhonen, S.2
James, R.D.3
Punt, C.J.A.4
Hickish, T.F.5
Heikkila, R.6
Johannesen, T.B.7
Starkhammar, H.8
Topham, C.A.9
Awad, L.10
Jacques, C.11
Herait, P.12
-
17
-
-
0032585197
-
Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer
-
DOI 10.1016/S0140-6736(98)03085-2
-
Rougier P, van Cutsem E, Bajetta E, Niederle N, Possinger K, Labianca R, et al: Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet 352: 1407-1412, 1998. (Pubitemid 28510873)
-
(1998)
Lancet
, vol.352
, Issue.9138
, pp. 1407-1412
-
-
Rougier, P.1
Van Cutsem, E.2
Bajetta, E.3
Niederle, N.4
Possinger, K.5
Labianca, R.6
Navarro, M.7
Morant, R.8
Bleiberg, H.9
Wils, J.10
Awad, L.11
Herait, P.12
Jacques, C.13
-
18
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone. as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, et al: Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 355: 1041-1047, 2000. (Pubitemid 30162806)
-
(2000)
Lancet
, vol.355
, Issue.9209
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
Jandik, P.7
Iveson, T.8
Carmichael, J.9
Alakl, M.10
Gruia, G.11
Awad, L.12
Rougier, P.13
-
19
-
-
0033995850
-
Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method
-
Takenoue T, Nagawa H, Matsuda K, Fujii S, Nita ME, Hatano K, et al: Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method. Ann Surg Oncol 7: 193-198, 2000. (Pubitemid 30215157)
-
(2000)
Annals of Surgical Oncology
, vol.7
, Issue.3
, pp. 193-198
-
-
Takenoue, T.1
Nagawa, H.2
Matsuda, K.3
Fujii, S.4
Nita, M.E.5
Hatano, K.6
Kitayama, J.7
Tsuruo, T.8
Muto, T.9
-
20
-
-
0033981858
-
Immunohistochemically detected thymidylate synthase in colorectal cancer: An independent prognostic factor of survival
-
Edler D, Kressner U, Ragnhammar P, Johnston PG, Magnusson I, Glimelius B, et al: Immunohistochemically detected thymidylate synthase in colorectal cancer: an independent prognostic factor of survival. Clin Cancer Res 6: 488-492, 2000. (Pubitemid 30111468)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.2
, pp. 488-492
-
-
Edler, D.1
Kressner, U.2
Ragnhammar, P.3
Johnston, P.G.4
Magnusson, I.5
Glimelius, B.6
Pahlman, L.7
Lindmark, G.8
Blomgren, H.9
-
21
-
-
0037096901
-
Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: Phenotypic and genotypic analyses
-
DOI 10.1200/JCO.2002.09.091
-
Etienne MC, Chazal M, Laurent-Puig P, Magne N, Rosty C, Formento JL, et al: Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: phenotypic and genotypic analyses. J Clin Oncol 20: 2832-2843, 2002. (Pubitemid 34651512)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.12
, pp. 2832-2843
-
-
Etienne, M.-C.1
Chazal, M.2
Laurent-Puig, P.3
Magne, N.4
Rosty, C.5
Formento, J.-L.6
Francoual, M.7
Formento, P.8
Renee, N.9
Chamorey, E.10
Bourgeon, A.11
Seitz, J.-F.12
Delpero, J.-R.13
Letoublon, C.14
Pezet, D.15
Milano, G.16
-
22
-
-
0033050310
-
Increased thymidylate synthase gene expression in liver metastases from colorectal carcinoma: Implications for chemotherapeutic options and survival
-
Bathe OF, Franceschi D, Livingstone AS, Moffat FL, Tian E and Ardalan B: Increased thymidylate synthase gene expression in liver metastases from colorectal carcinoma: implications for chemotherapeutic options and survival. Cancer J Sci Am 5: 34-40, 1999. (Pubitemid 29108644)
-
(1999)
Cancer Journal from Scientific American
, vol.5
, Issue.1
, pp. 34-40
-
-
Bathe, O.F.1
Franceschi, D.2
Livingstone, A.S.3
Moffat, F.L.4
Tian, E.5
Ardalan, B.6
-
23
-
-
0032997572
-
Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil- based chemotherapy
-
Aschele C, Debernardis D, Casazza S, Antonelli G, Tunesi G, Baldo C, et al: Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy. J Clin Oncol 17: 1760-1770, 1999. (Pubitemid 29269245)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.6
, pp. 1760-1770
-
-
Aschele, C.1
Debernardis, D.2
Casazza, S.3
Antonelli, G.4
Tunesi, G.5
Baldo, C.6
Lionetto, R.7
Maley, F.8
Sobrero, A.9
-
24
-
-
6544276581
-
Thymidylate synthase protein expression in advanced colon cancer: Correlation with the site of metastasis and the clinical response to leucovorin-modulated bolus 5-fluorouracil
-
Cascinu S, Aschele C, Barni S, Debernardis D, Baldo C, Tunesi G et al: Thymidylate synthase protein expression in advanced colon cancer: correlation with the site of metastasis and the clinical response to leucovorin-modulated bolus 5-fluorouracil Clin Cancer Res 5: 1996-1999, 1999. (Pubitemid 29399249)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.8
, pp. 1996-1999
-
-
Cascinu, S.1
Aschele, C.2
Barni, S.3
Debernardis, D.4
Baldo, C.5
Tunesi, G.6
Catalano, V.7
Staccioli, M.P.8
Brenna, A.9
Muretto, P.10
Catalano, G.11
-
25
-
-
0033009501
-
Colorectal liver metastasis thymidylate synthase staining correlates with response to hepatic arterial floxuridine
-
Davies MM, Johnston PG, Kaur S and Allen-Mersh TG: Colorectal liver metastasis thymidylate synthase staining correlates with response to hepatic arterial floxuridine. Clin Cancer Res 5: 325-328, 1999. (Pubitemid 29085185)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.2
, pp. 325-328
-
-
Davies, M.M.1
Johnston, P.G.2
Kaur, S.3
Allen-Mersh, T.G.4
-
26
-
-
0030883708
-
Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted- infusion fluorouracil and weekly leucovorin
-
Leichman CG, Lenz HJ, Leichman L, Danenberg K, Baranda J, Groshen S, et al: Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J Clin Oncol 15: 3223-3229, 1997. (Pubitemid 27419335)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.10
, pp. 3223-3229
-
-
Leichman, C.G.1
Lenz, H.-J.2
Leichman, L.3
Danenberg, K.4
Baranda, J.5
Groshen, S.6
Boswell, W.7
Metzger, R.8
Tan, M.9
Danenberg, P.V.10
-
27
-
-
0038312248
-
Apoptotic index and bcl-2 expression as prognostic factors in colorectal carcinoma
-
DOI 10.1159/000070304
-
Bendardaf R, Ristamaki R, Kujari H, Laine J, Lamlum H, Collan Y, et al: Apoptotic index and bcl-2 expression as prognostic factors in colorectal carcinoma. Oncology 64: 435-442, 2003. (Pubitemid 36682959)
-
(2003)
Oncology
, vol.64
, Issue.4
, pp. 435-442
-
-
Bendardaf, R.1
Ristamaki, R.2
Kujari, H.3
Laine, J.4
Lamlum, H.5
Collan, Y.6
Pyrhonen, S.7
-
28
-
-
0025204548
-
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
-
Hockenbery D, Nunez G, Milliman C, Schreiber RD and Korsmeyer SJ: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336, 1990. (Pubitemid 120029101)
-
(1990)
Nature
, vol.348
, Issue.6299
, pp. 334-336
-
-
Hockenbery, D.1
Ninez, G.2
Milliman, C.3
Schreiber, R.D.4
Korsmeyer, S.J.5
-
29
-
-
0032712426
-
bcl-2 protein expression is associated with better prognosis in colorectal cancer
-
DOI 10.1046/j.1365-2559.1999.00743.x
-
Leahy DT, Mulcahy HE, O'Donoghue DP and Parfrey NA: bcl-2 protein expression is associated with better prognosis in colorectal cancer. Histopathology 35: 360-367, 1999. (Pubitemid 29502355)
-
(1999)
Histopathology
, vol.35
, Issue.4
, pp. 360-367
-
-
Leahy, D.T.1
Mulcahy, H.E.2
O'Donoghue, D.P.3
Parfrey, N.A.4
-
30
-
-
0035878611
-
TNM classification: Clarification of number of regional lymph nodes for pNO
-
DOI 10.1002/1097-0142(20010715)92:2<452::AID
-
Sobin LH and Greene FL: TNM classification: clarification of number of regional lymph nodes for pNo. Cancer 92: 452, 2001. (Pubitemid 32664454)
-
(2001)
Cancer
, vol.92
, Issue.2
, pp. 452
-
-
Sobin, L.H.1
Greene, F.L.2
|