-
1
-
-
0031038918
-
Alzheimer's disease: Genotypes, phenotype and treatments
-
Selkoe DJ. Alzheimer's disease: genotypes, phenotype and treatments. Science 275(5300):630-1 (1997).
-
(1997)
Science
, vol.275
, Issue.5300
, pp. 630-631
-
-
Selkoe, D.J.1
-
2
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J and Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297: 353-356 (2002).
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
3
-
-
0027379395
-
Characterization of β-amyloid peptide from human cerebrospinal fluid
-
Vigo-Pelfrey C, Lee D, Keim P, Lieberberg I and Schenk DB. Characterization of β-amyloid peptide from human cerebrospinal fluid. J Neurochem 61: 1965-1968 (1993).
-
(1993)
J Neurochem
, vol.61
, pp. 1965-1968
-
-
Vigo-Pelfrey, C.1
Lee, D.2
Keim, P.3
Lieberberg, I.4
Schenk, D.B.5
-
4
-
-
0028919919
-
Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down's syndrome
-
Iwatsubo T, Mann DAM, Odaka A, Suzuki N and Ihara Y. Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down's syndrome. Ann Neurol 37: 294-299 (1995).
-
(1995)
Ann Neurol
, vol.37
, pp. 294-299
-
-
Iwatsubo, T.1
Mann, D.A.M.2
Odaka, A.3
Suzuki, N.4
Ihara, Y.5
-
5
-
-
0026512066
-
Identification of normal and pathological aging in prospectively studied nondemented elderly humans
-
Dickson DW, Crystal HA, Mattiace LA, Masur DM, Blau AD, Davies P, et al. Identification of normal and pathological aging in prospectively studied nondemented elderly humans. Neurobiol Aging 13: 1-11 (1992).
-
(1992)
Neurobiol Aging
, vol.13
, pp. 1-11
-
-
Dickson, D.W.1
Crystal, H.A.2
Mattiace, L.A.3
Masur, D.M.4
Blau, A.D.5
Davies, P.6
-
6
-
-
0029849644
-
Full-lenght amyloid-β(1-42(43)) and amino-terminally modified and truncated amyloid-β42(43) deposit in diffuse plaques
-
Iwatsubo T, Saido TC, Mann DMA, Lee V M-Y and Trojanowski JQ. Full-lenght amyloid-β(1-42(43)) and amino-terminally modified and truncated amyloid-β42(43) deposit in diffuse plaques. Am J Pathol 149: 1823-1830 (1996).
-
(1996)
Am J Pathol
, vol.149
, pp. 1823-1830
-
-
Iwatsubo, T.1
Saido, T.C.2
Mann, D.M.A.3
Lee, V.M.-Y.4
Trojanowski, J.Q.5
-
7
-
-
0030035922
-
p3 β-amyloid peptide has a unique and potentially pathogenic immunohistochemical profile in Alzheimer's disease brain
-
Higgins L, Murphy Jr GM, Forno LS, Catalano R and Cordell B. p3 β-amyloid peptide has a unique and potentially pathogenic immunohistochemical profile in Alzheimer's disease brain. Am J Path 149: 585-596 (1996).
-
(1996)
Am J Path
, vol.149
, pp. 585-596
-
-
Higgins, L.1
Murphy Jr., G.M.2
Forno, L.S.3
Catalano, R.4
Cordell, B.5
-
8
-
-
0001792809
-
Antibodies directed to the carboxyl terminus of amyloid β-peptide recognize sequence epitopes and distinct immunoreactive deposits in Alzheimer's disease brain
-
Jimenez-Huete A, Alfonso P, Soto C, Alvar JP, Rábano A, Ghiso J, et al. Antibodies directed to the carboxyl terminus of amyloid β-peptide recognize sequence epitopes and distinct immunoreactive deposits in Alzheimer's disease brain. Alzheimer's Reports 1: 41-48 (1998).
-
(1998)
Alzheimer's Reports
, vol.1
, pp. 41-48
-
-
Jimenez-Huete, A.1
Alfonso, P.2
Soto, C.3
Alvar, J.P.4
Rábano, A.5
Ghiso, J.6
-
9
-
-
0006050973
-
Monoclonal antibody technology
-
(Eds: Burdon RH, Knippenberg PH) Elsevier, Amsterdam
-
Campbell A. Monoclonal antibody technology In: 'Laboratory Techniques in Biochemistry and Molecular Biology' (Eds: Burdon RH, Knippenberg PH) Elsevier, Amsterdam, p. 120-134 (1984).
-
(1984)
Laboratory Techniques in Biochemistry and Molecular Biology
, pp. 120-134
-
-
Campbell, A.1
-
10
-
-
0025908356
-
Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
-
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)
-
Mirra, SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, van Belle G and Berg L. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 41: 479-486 (1991).
-
(1991)
Neurology
, vol.41
, pp. 479-486
-
-
Mirra, S.S.1
Heyman, A.2
McKeel, D.3
Sumi, S.M.4
Crain, B.J.5
Brownlee, L.M.6
Vogel, F.S.7
Hughes, J.P.8
Van Belle, G.9
Berg, L.10
-
11
-
-
0028919919
-
Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down's syndrome
-
Iwatsubo T, Mann DAM, Odaka A, Suzuki N and Ihara Y. Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down's syndrome. Ann Neurol 37: 294-299 (1995).
-
(1995)
Ann Neurol
, vol.37
, pp. 294-299
-
-
Iwatsubo, T.1
Dam, M.2
Odaka, A.3
Suzuki, N.4
Ihara, Y.5
-
12
-
-
0030064140
-
Amyloid β protein deposition in normal aging has the same characteristics as that in Alzheimer's disease
-
Fukumoto H, Asami-Okada A, Suzuki N, Shimada H, Ihara Y and Iwatsubo T. Amyloid β protein deposition in normal aging has the same characteristics as that in Alzheimer's disease. Am J Pathol 148: 259-265 (1996).
-
(1996)
Am J Pathol
, vol.148
, pp. 259-265
-
-
Fukumoto, H.1
Asami-Okada, A.2
Suzuki, N.3
Shimada, H.4
Ihara, Y.5
Iwatsubo, T.6
-
13
-
-
0024496624
-
Down syndrome patients: Extracellular preamyloid deposits precede neuritic degeneration and senile plaques
-
Giaccone G, Tagliavini F, Linoli G, Bouras C, Frigerior L, Frangione B, et al. Down syndrome patients: extracellular preamyloid deposits precede neuritic degeneration and senile plaques. Neurosci Lett 97: 232-238 (1989).
-
(1989)
Neurosci Lett
, vol.97
, pp. 232-238
-
-
Giaccone, G.1
Tagliavini, F.2
Linoli, G.3
Bouras, C.4
Frigerior, L.5
Frangione, B.6
-
14
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
-
Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, Hill R, et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30: 572-580 (1991).
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
Deteresa, R.5
Hill, R.6
-
15
-
-
0025600931
-
Diffuse plaques do not accentuate synapse loss in Alzheimer Disease
-
Masliah E, Terry RD, Mallory M, Alford M and Hansen LA. Diffuse plaques do not accentuate synapse loss in Alzheimer Disease. Am J Path 137: 1293-97 (1990).
-
(1990)
Am J Path
, vol.137
, pp. 1293-1297
-
-
Masliah, E.1
Terry, R.D.2
Mallory, M.3
Alford, M.4
Hansen, L.A.5
-
16
-
-
0030669036
-
The pathogenesis of senile plaques
-
Dickson DW. The pathogenesis of senile plaques. J Neuropathol Exp Neurol 56: 321-339 (1997).
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 321-339
-
-
Dickson, D.W.1
-
17
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H and Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathologica (Berl) 82: 239-259 (1991).
-
(1991)
Acta Neuropathologica (Berl)
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
18
-
-
0033624303
-
Sequence of Aβ-protein deposition in the human medial temporal lobe
-
Thal DR, Rüb U, Schultz Ch, Sassin I, Ghebremedhin S, Del Tredici K, et al. Sequence of Aβ-protein deposition in the human medial temporal lobe. J Neuropathol Exp Neurol 59 (8): 733-748 (2000).
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, Issue.8
, pp. 733-748
-
-
Thal, D.R.1
Rüb, U.2
Schultz, Ch.3
Sassin, I.4
Ghebremedhin, S.5
Del Tredici, K.6
-
19
-
-
0028179341
-
Chemical characterization of Aβ 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease
-
Gowing E, Roher AE, Woods AS, Cotter RJ, Chaney M, Little SP, et al. Chemical characterization of Aβ 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease. J Biol Chem 269: 10987-10990 (1994).
-
(1994)
J Biol Chem
, vol.269
, pp. 10987-10990
-
-
Gowing, E.1
Roher, A.E.2
Woods, A.S.3
Cotter, R.J.4
Chaney, M.5
Little, S.P.6
-
20
-
-
0028980163
-
Early amyloid-β deposits show different immunoreactivity to the amino- and carboxy-terminal regions of β-peptide in Alzheimer's disease and Down's syndrome brain
-
Kida E, Wisniewski KE and Wisniewski HM. Early amyloid-β deposits show different immunoreactivity to the amino- and carboxy-terminal regions of β-peptide in Alzheimer's disease and Down's syndrome brain. Neurosc Lett 193: 105-108 (1995).
-
(1995)
Neurosc Lett
, vol.193
, pp. 105-108
-
-
Kida, E.1
Wisniewski, K.E.2
Wisniewski, H.M.3
-
21
-
-
0030300022
-
The "nonamyloidogenic" p3 fragment (amyloid β17-42) is a major constituent of Down's syndrome cerebellar preamyloid
-
Lalowski M, Golabek A, Lemere A, Selkoe DJ, Wisniewski HM, Beavis RC, Frangione B and Wisniewski T. The "nonamyloidogenic" p3 fragment (amyloid β17-42) is a major constituent of Down's syndrome cerebellar preamyloid. J Biol Chem 271: 33623-33631 (1994).
-
(1994)
J Biol Chem
, vol.271
, pp. 33623-33631
-
-
Lalowski, M.1
Golabek, A.2
Lemere, A.3
Selkoe, D.J.4
Wisniewski, H.M.5
Beavis, R.C.6
Frangione, B.7
Wisniewski, T.8
-
22
-
-
0028855851
-
Dominant and differential deposition of distinct β-amyloid peptide species, AβN3(pE) in senile plaques
-
Saido TC, Iwatsubo T, Mann DMA, Shimada H, Ihara Y and Kawashima S. Dominant and differential deposition of distinct β-amyloid peptide species, AβN3(pE) in senile plaques. Neuron, 14: 457-466 (1995).
-
(1995)
Neuron
, vol.14
, pp. 457-466
-
-
Saido, T.C.1
Iwatsubo, T.2
Mann, D.M.A.3
Shimada, H.4
Ihara, Y.5
Kawashima, S.6
-
23
-
-
0031985080
-
N-terminal heterogeneity of parenchimal and cerebrovascular Aβ deposits
-
Tekirian TL, Saido TC, Markesberry WR, Russell MJ, Wekstein DR, Patel E, et al. N-terminal heterogeneity of parenchimal and cerebrovascular Aβ deposits. J Neuropath Exp Neurol 57: 76-94 (1998).
-
(1998)
J Neuropath Exp Neurol
, vol.57
, pp. 76-94
-
-
Tekirian, T.L.1
Saido, T.C.2
Markesberry, W.R.3
Russell, M.J.4
Wekstein, D.R.5
Patel, E.6
-
24
-
-
0032815498
-
Hypothesis: Amyloid β-peptides truncated at the N-terminus contribute to the pathogenesis of Alzheimer's disease
-
Lamer AJ. Hypothesis: amyloid β-peptides truncated at the N-terminus contribute to the pathogenesis of Alzheimer's disease. Neurobiol Aging 20: 65-69 (1999).
-
(1999)
Neurobiol Aging
, vol.20
, pp. 65-69
-
-
Lamer, A.J.1
-
25
-
-
0034747316
-
Correlation between Aβx-40-, Aβx-42-, and Aβx-43- containing amyloid plaques and cognitive decline
-
Parvathy S, Davis P, Haroutunian V, Purohit DP, Davis KL, Mohs RC, et al. Correlation between Aβx-40-, Aβx-42-, and Aβx-43-containing amyloid plaques and cognitive decline. Arch Neurol 58: 2025-2032 (2001).
-
(2001)
Arch Neurol
, vol.58
, pp. 2025-2032
-
-
Parvathy, S.1
Davis, P.2
Haroutunian, V.3
Purohit, D.P.4
Davis, K.L.5
Mohs, R.C.6
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