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Volumn 46, Issue 3, 2005, Pages 165-173

Recent advances in the treatment of pulmonary hypertension

Author keywords

Advanced therapies; Congenital heart disease; Pulmonary arterial hypertension

Indexed keywords

BERAPROST; BOSENTAN; CALCIUM CHANNEL BLOCKING AGENT; DIGOXIN; DIURETIC AGENT; ILOPROST; NITRIC OXIDE; OXYGEN; PROSTACYCLIN; SILDENAFIL; UNIPROST; WARFARIN; ANTIHYPERTENSIVE AGENT; VASODILATOR AGENT;

EID: 24644445270     PISSN: 10117970     EISSN: 10117970     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (1)

References (85)
  • 1
    • 0034727717 scopus 로고    scopus 로고
    • Primary pulmonary hypertension: A vascular biology and translational research "Work in progress"
    • Archer S, Rich S: Primary pulmonary hypertension: a vascular biology and translational research "Work in progress". Circulation 2000; 102: 2781-2791.
    • (2000) Circulation , vol.102 , pp. 2781-2791
    • Archer, S.1    Rich, S.2
  • 2
    • 5344233478 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension
    • Farber HW, Loscalzo J: Pulmonary arterial hypertension. N Engl J Med 2004; 351: 1655-1665.
    • (2004) N Engl J Med , vol.351 , pp. 1655-1665
    • Farber, H.W.1    Loscalzo, J.2
  • 3
    • 2942522878 scopus 로고    scopus 로고
    • Clinical classification of pulmonary hypertension
    • Simonneau G, Galie N, Rubin LJ, et al: Clinical classification of pulmonary hypertension. J Am Coll Cardiol 2004; 43: 5S-12S.
    • (2004) J Am Coll Cardiol , vol.43
    • Simonneau, G.1    Galie, N.2    Rubin, L.J.3
  • 4
    • 0023615359 scopus 로고
    • Primary pulmonary hypertension. A national prospective study
    • Rich S, Dantzker DR, Ayres SM, et al: Primary pulmonary hypertension. A national prospective study. Ann Intern Med 1987; 107: 216-223.
    • (1987) Ann Intern Med , vol.107 , pp. 216-223
    • Rich, S.1    Dantzker, D.R.2    Ayres, S.M.3
  • 5
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension. Results from a national prospective registry
    • D'Alonzo GE, Barst RJ, Ayres SM, et al: Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med 1991; 115: 343-349.
    • (1991) Ann Intern Med , vol.115 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3
  • 7
    • 0037118681 scopus 로고    scopus 로고
    • Assessment of survival in patients with primary pulmonary hypertension: Importance of cardiopulmonary exercise testing
    • Wensel R, Opitz CF, Anker SD, et al: Assessment of survival in patients with primary pulmonary hypertension: importance of cardiopulmonary exercise testing. Circulation 2002; 106: 319-324.
    • (2002) Circulation , vol.106 , pp. 319-324
    • Wensel, R.1    Opitz, C.F.2    Anker, S.D.3
  • 8
    • 0037126044 scopus 로고    scopus 로고
    • Survival in primary pulmonary hypertension: The impact of epoprostenol therapy
    • McLaughlin VV, Shillington A, Rich S: Survival in primary pulmonary hypertension: the impact of epoprostenol therapy. Circulation 2002; 106: 1477-1482.
    • (2002) Circulation , vol.106 , pp. 1477-1482
    • McLaughlin, V.V.1    Shillington, A.2    Rich, S.3
  • 9
    • 0036433327 scopus 로고    scopus 로고
    • Significance of a plasma D-dimer test in patients with primary pulmonary hypertension
    • Shitrit D, Bendayan D, Bar-Gil-Shitrit A, et al: Significance of a plasma D-dimer test in patients with primary pulmonary hypertension. Chest 2002; 122: 1674-1678.
    • (2002) Chest , vol.122 , pp. 1674-1678
    • Shitrit, D.1    Bendayan, D.2    Bar-Gil-Shitrit, A.3
  • 10
    • 0038301318 scopus 로고    scopus 로고
    • Right atrial size and tricuspid regurgitation severity predict mortality or transplantation in primary pulmonary hypertension
    • Bustamante-Labarta M, Perrone S, De La Fuente RL, et al: Right atrial size and tricuspid regurgitation severity predict mortality or transplantation in primary pulmonary hypertension. J Am Soc Echocardiogr 2002; 15:1160-1164.
    • (2002) J Am Soc Echocardiogr , vol.15 , pp. 1160-1164
    • Bustamante-Labarta, M.1    Perrone, S.2    De La Fuente, R.L.3
  • 11
    • 0018129644 scopus 로고
    • Longterm favorable effect of oxygen administration on a patient with primary pulmonary hypertension
    • Nagasaka Y, Akutsu H, Lee YS, Fujimoto S, Chikamori J: Longterm favorable effect of oxygen administration on a patient with primary pulmonary hypertension. Chest 1978; 74: 299-300.
    • (1978) Chest , vol.74 , pp. 299-300
    • Nagasaka, Y.1    Akutsu, H.2    Lee, Y.S.3    Fujimoto, S.4    Chikamori, J.5
  • 12
    • 0033101528 scopus 로고    scopus 로고
    • Combined effects of nitric oxide and oxygen during acute pulmonary vasodilator testing
    • Atz AM, Adatia I, Lock JE, Wessel DL: Combined effects of nitric oxide and oxygen during acute pulmonary vasodilator testing. J Am Coll Cardiol 1999; 33: 813-819.
    • (1999) J Am Coll Cardiol , vol.33 , pp. 813-819
    • Atz, A.M.1    Adatia, I.2    Lock, J.E.3    Wessel, D.L.4
  • 13
    • 0035170216 scopus 로고    scopus 로고
    • Oxygen therapy improves cardiac index and pulmonary vascular resistance in patients with pulmonary hypertension
    • Roberts DH, Lepore JJ, Maroo A, Semigran MJ, Ginns LC: Oxygen therapy improves cardiac index and pulmonary vascular resistance in patients with pulmonary hypertension. Chest 2001; 120: 1547-1555.
    • (2001) Chest , vol.120 , pp. 1547-1555
    • Roberts, D.H.1    Lepore, J.J.2    Maroo, A.3    Semigran, M.J.4    Ginns, L.C.5
  • 14
    • 0026029151 scopus 로고
    • Hypoxic pulmonary vasoconstriction in systemic sclerosis and primary pulmonary hypertension
    • Morgan JM, Griffiths M, du Bois RM, Evans TW: Hypoxic pulmonary vasoconstriction in systemic sclerosis and primary pulmonary hypertension. Chest 1991; 99: 551-556.
    • (1991) Chest , vol.99 , pp. 551-556
    • Morgan, J.M.1    Griffiths, M.2    Du Bois, R.M.3    Evans, T.W.4
  • 15
    • 0022454598 scopus 로고
    • Systemic vasoconstrictor effects of oxygen administration in obliterative pulmonary vascular disorders
    • Packer M, Lee WH, Medina N, Yushak M: Systemic vasoconstrictor effects of oxygen administration in obliterative pulmonary vascular disorders. Am J Cardiol 1986; 57: 853-858.
    • (1986) Am J Cardiol , vol.57 , pp. 853-858
    • Packer, M.1    Lee, W.H.2    Medina, N.3    Yushak, M.4
  • 16
    • 0035508410 scopus 로고    scopus 로고
    • Nocturnal oxygen therapy in patients with the Eisenmenger syndrome
    • Sandoval J, Aguirre JS, Pulido T, et al: Nocturnal oxygen therapy in patients with the Eisenmenger syndrome. Am J Respir Crit Care Med 2001; 164: 1682-1687.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1682-1687
    • Sandoval, J.1    Aguirre, J.S.2    Pulido, T.3
  • 17
    • 0022646182 scopus 로고
    • Effect of long term oxygen treatment at home in children with pulmonary vascular disease
    • Bowyer JJ, Busst CM, Denison DM, Shinebourne EA: Effect of long term oxygen treatment at home in children with pulmonary vascular disease. Br Heart J 1986; 55: 385-390.
    • (1986) Br Heart J , vol.55 , pp. 385-390
    • Bowyer, J.J.1    Busst, C.M.2    Denison, D.M.3    Shinebourne, E.A.4
  • 18
    • 0030447832 scopus 로고    scopus 로고
    • Coagulation and fibrinolytic profiles in patients with severe pulmonary hypertension
    • Welsh CH, Hassell KL, Badesch DB, Kressin DC, Marlar RA: Coagulation and fibrinolytic profiles in patients with severe pulmonary hypertension. Chest 1996; 110: 710-717.
    • (1996) Chest , vol.110 , pp. 710-717
    • Welsh, C.H.1    Hassell, K.L.2    Badesch, D.B.3    Kressin, D.C.4    Marlar, R.A.5
  • 19
    • 0026632785 scopus 로고
    • The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
    • Rich S, Kaufmann E, Levy PS: The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med 1992; 327: 76-81.
    • (1992) N Engl J Med , vol.327 , pp. 76-81
    • Rich, S.1    Kaufmann, E.2    Levy, P.S.3
  • 20
    • 16544367920 scopus 로고    scopus 로고
    • Massive pulmonary artery thrombosis with haemoptysis in adults with Eisenmenger's syndrome: A clinical dilemma
    • Broberg C, Ujita M, Babu-Narayan S, et al: Massive pulmonary artery thrombosis with haemoptysis in adults with Eisenmenger's syndrome: a clinical dilemma. Heart 2004; 90:e63.
    • (2004) Heart , vol.90
    • Broberg, C.1    Ujita, M.2    Babu-Narayan, S.3
  • 21
    • 2942603006 scopus 로고    scopus 로고
    • Diagnosis and differential assessment of pulmonary arterial hypertension
    • Barst RJ, McGoon M, Torbicki A, et al: Diagnosis and differential assessment of pulmonary arterial hypertension. J Am Coll Cardiol 2004; 43: 40S-47S.
    • (2004) J Am Coll Cardiol , vol.43
    • Barst, R.J.1    McGoon, M.2    Torbicki, A.3
  • 22
    • 0034868447 scopus 로고    scopus 로고
    • Recommendations on the management of pulmonary hypertension in clinical practice
    • Recommendations on the management of pulmonary hypertension in clinical practice: Heart 2001; 86: 1i-13.
    • (2001) Heart , vol.86
  • 23
    • 0038799768 scopus 로고    scopus 로고
    • Pulmonary hypertension in systemic sclerosis
    • Denton CP, Black CM: Pulmonary hypertension in systemic sclerosis. Rheum Dis Clin North Am 2003; 29: 335-349, vii.
    • (2003) Rheum Dis Clin North Am , vol.29 , pp. 335-349
    • Denton, C.P.1    Black, C.M.2
  • 24
    • 0031719459 scopus 로고    scopus 로고
    • The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension
    • Rich S, Seidlitz M, Dodin E, et al: The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension. Chest 1998; 114: 787-792.
    • (1998) Chest , vol.114 , pp. 787-792
    • Rich, S.1    Seidlitz, M.2    Dodin, E.3
  • 25
    • 0026005686 scopus 로고
    • Adenosine as a vasodilator in primary pulmonary hypertension
    • Morgan JM, McCormack DG, Griffiths MJ, et al: Adenosine as a vasodilator in primary pulmonary hypertension. Circulation 1991; 84: 1145-1149.
    • (1991) Circulation , vol.84 , pp. 1145-1149
    • Morgan, J.M.1    McCormack, D.G.2    Griffiths, M.J.3
  • 26
    • 0037150158 scopus 로고    scopus 로고
    • Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: Comparison with inhaled nitric oxide
    • Michelakis E, Tymchak W, Lien D, Webster L, Hashimoto K, Archer S: Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide. Circulation 2002; 105: 2398-2403.
    • (2002) Circulation , vol.105 , pp. 2398-2403
    • Michelakis, E.1    Tymchak, W.2    Lien, D.3    Webster, L.4    Hashimoto, K.5    Archer, S.6
  • 27
    • 0033213243 scopus 로고    scopus 로고
    • The effects of chronic prostacyclin therapy on cardiac output and symptoms in primary pulmonary hypertension
    • Rich S, McLaughlin VV: The effects of chronic prostacyclin therapy on cardiac output and symptoms in primary pulmonary hypertension. J Am Coll Cardiol 1999; 34: 1184-1187.
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1184-1187
    • Rich, S.1    McLaughlin, V.V.2
  • 28
    • 4644290657 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension
    • Humbert M, Sitbon O, Simonneau G: Treatment of pulmonary arterial hypertension. N Engl J Med 2004; 351: 1425-1436.
    • (2004) N Engl J Med , vol.351 , pp. 1425-1436
    • Humbert, M.1    Sitbon, O.2    Simonneau, G.3
  • 29
    • 0030031888 scopus 로고    scopus 로고
    • A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
    • The Primary Pulmonary Hypertension Study Group
    • Barst RJ, Rubin LJ, Long WA, et al: A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. N Engl J Med 1996; 334: 296-302.
    • (1996) N Engl J Med , vol.334 , pp. 296-302
    • Barst, R.J.1    Rubin, L.J.2    Long, W.A.3
  • 30
    • 17144452827 scopus 로고    scopus 로고
    • Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial
    • Badesch DB, Tapson VF, McGoon MD, et al: Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial. Ann Intern Med 2000; 132: 425-434.
    • (2000) Ann Intern Med , vol.132 , pp. 425-434
    • Badesch, D.B.1    Tapson, V.F.2    McGoon, M.D.3
  • 31
    • 0033537630 scopus 로고    scopus 로고
    • Vasodilator therapy for primary pulmonary hypertension in children
    • Barst RJ, Maislin G, Fishman AP: Vasodilator therapy for primary pulmonary hypertension in children. Circulation 1999; 99: 1197-1208.
    • (1999) Circulation , vol.99 , pp. 1197-1208
    • Barst, R.J.1    Maislin, G.2    Fishman, A.P.3
  • 32
    • 0037261439 scopus 로고    scopus 로고
    • Intermittent epoprostenol infusions in systemic lupus erythematosus associated pulmonary hypertension - A series of three cases
    • Kong KO, Badsha H, Thumboo J, Chng HH: Intermittent epoprostenol infusions in systemic lupus erythematosus associated pulmonary hypertension -a series of three cases. Ann Acad Med Singapore 2003; 32: 118-121.
    • (2003) Ann Acad Med Singapore , vol.32 , pp. 118-121
    • Kong, K.O.1    Badsha, H.2    Thumboo, J.3    Chng, H.H.4
  • 33
    • 0032576672 scopus 로고    scopus 로고
    • Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension
    • McLaughlin VV, Genthner DE, Panella MM, Rich S: Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension. N Engl J Med 1998; 338: 273-277.
    • (1998) N Engl J Med , vol.338 , pp. 273-277
    • McLaughlin, V.V.1    Genthner, D.E.2    Panella, M.M.3    Rich, S.4
  • 34
    • 0036808874 scopus 로고    scopus 로고
    • Effects and problems of continuous infusion of epoprostenol for patients with primary pulmonary hypertension
    • Takahashi T, Sakuma M, Ikeda J, et al: Effects and problems of continuous infusion of epoprostenol for patients with primary pulmonary hypertension. Intern Med 2002; 41: 784-788.
    • (2002) Intern Med , vol.41 , pp. 784-788
    • Takahashi, T.1    Sakuma, M.2    Ikeda, J.3
  • 35
    • 0037151645 scopus 로고    scopus 로고
    • Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: Prognostic factors and survival
    • Sitbon O, Humbert M, Nunes H, et al: Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival. J Am Coll Cardiol 2002; 40: 780-788.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 780-788
    • Sitbon, O.1    Humbert, M.2    Nunes, H.3
  • 36
    • 0034949077 scopus 로고    scopus 로고
    • Trials of inhaled iloprost and other new vasodilating prostaglandins
    • Higenbottam T, Siddons T: Trials of inhaled iloprost and other new vasodilating prostaglandins. Eur Respir J 2001; 17: 6-7.
    • (2001) Eur Respir J , vol.17 , pp. 6-7
    • Higenbottam, T.1    Siddons, T.2
  • 37
    • 0037322944 scopus 로고    scopus 로고
    • Assessment of the vasodilator response in primary pulmonary hypertension. Comparing prostacyclin and iloprost administered by either infusion or inhalation
    • Opitz CF, Wensel R, Bettmann M, et al: Assessment of the vasodilator response in primary pulmonary hypertension. Comparing prostacyclin and iloprost administered by either infusion or inhalation. Eur Heart J 2003; 24: 356-365.
    • (2003) Eur Heart J , vol.24 , pp. 356-365
    • Opitz, C.F.1    Wensel, R.2    Bettmann, M.3
  • 38
    • 12244251412 scopus 로고    scopus 로고
    • Efficacy and safety of treprostinil: An epoprostenol analog for primary pulmonary hypertension
    • McLaughlin VV, Gaine SP, Barst RJ, et al: Efficacy and safety of treprostinil: an epoprostenol analog for primary pulmonary hypertension. J Cardiovasc Pharmacol 2003; 41: 293-299.
    • (2003) J Cardiovasc Pharmacol , vol.41 , pp. 293-299
    • McLaughlin, V.V.1    Gaine, S.P.2    Barst, R.J.3
  • 39
    • 0035192113 scopus 로고    scopus 로고
    • Long term treatment of pulmonary arterial hypertension with beraprost, an oral prostacyclin analogue
    • Vizza CD, Sciomer S, Morelli S, et al: Long term treatment of pulmonary arterial hypertension with beraprost, an oral prostacyclin analogue. Heart 2001; 86: 661-665.
    • (2001) Heart , vol.86 , pp. 661-665
    • Vizza, C.D.1    Sciomer, S.2    Morelli, S.3
  • 40
    • 0038037766 scopus 로고    scopus 로고
    • Beraprost therapy for pulmonary arterial hypertension
    • Barst RJ, McGoon M, McLaughlin V, et al: Beraprost therapy for pulmonary arterial hypertension. J Am Coll Cardiol 2003; 41: 2119-2125.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 2119-2125
    • Barst, R.J.1    McGoon, M.2    McLaughlin, V.3
  • 41
    • 0038555341 scopus 로고    scopus 로고
    • Effect of orally active prostacyclin analogue on survival in patients with chronic thromboembolic pulmonary hypertension without major vessel obstruction
    • Ono F, Nagaya N, Okumura H, et al: Effect of orally active prostacyclin analogue on survival in patients with chronic thromboembolic pulmonary hypertension without major vessel obstruction. Chest 2003; 123: 1583-1588.
    • (2003) Chest , vol.123 , pp. 1583-1588
    • Ono, F.1    Nagaya, N.2    Okumura, H.3
  • 42
    • 0032781445 scopus 로고    scopus 로고
    • Development of nonspecific interstitial pneumonias associated with longterm treatment of primary pulmonary hypertension with prostacyclin
    • Kesten S, Dainauskas J, McLaughlin V, Rich S: Development of nonspecific interstitial pneumonias associated with longterm treatment of primary pulmonary hypertension with prostacyclin. Chest 1999; 116: 566-569.
    • (1999) Chest , vol.116 , pp. 566-569
    • Kesten, S.1    Dainauskas, J.2    McLaughlin, V.3    Rich, S.4
  • 43
    • 0033977505 scopus 로고    scopus 로고
    • A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension
    • German PPH study group
    • Hoeper MM, Olschewski H, Ghofrani HA, et al: A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study group. J Am Coll Cardiol 2000; 35: 176-182.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 176-182
    • Hoeper, M.M.1    Olschewski, H.2    Ghofrani, H.A.3
  • 44
    • 0029095930 scopus 로고
    • Cost implications of using inhaled nitric oxide compared with epoprostenol for pulmonary hypertension
    • Petros AJ, Turner SC, Nunn AJ: Cost implications of using inhaled nitric oxide compared with epoprostenol for pulmonary hypertension. J Pharm Technol 1995; 11:163-166.
    • (1995) J Pharm Technol , vol.11 , pp. 163-166
    • Petros, A.J.1    Turner, S.C.2    Nunn, A.J.3
  • 45
    • 0035292140 scopus 로고    scopus 로고
    • Inhaled nitric oxide and congenital cardiac disease
    • Beghetti M, Adatia I: Inhaled nitric oxide and congenital cardiac disease. Cardiol Young 2001; 11: 142-152.
    • (2001) Cardiol Young , vol.11 , pp. 142-152
    • Beghetti, M.1    Adatia, I.2
  • 46
    • 0034713874 scopus 로고    scopus 로고
    • Hemodynamic effects of Bosentan, an endothelin receptor antagonist, in patients with pulmonary hypertension
    • Williamson DJ, Wallman LL, Jones R, et al: Hemodynamic effects of Bosentan, an endothelin receptor antagonist, in patients with pulmonary hypertension. Circulation 2000; 102: 411-418.
    • (2000) Circulation , vol.102 , pp. 411-418
    • Williamson, D.J.1    Wallman, L.L.2    Jones, R.3
  • 47
    • 0037484589 scopus 로고    scopus 로고
    • Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension: A 1-year follow-up study
    • Sitbon O, Badesch DB, Channick RN, et al: Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension: a 1-year follow-up study. Chest 2003; 124: 247-254.
    • (2003) Chest , vol.124 , pp. 247-254
    • Sitbon, O.1    Badesch, D.B.2    Channick, R.N.3
  • 48
    • 0344837813 scopus 로고    scopus 로고
    • Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and doppler measures in patients with pulmonary arterial hypertension
    • Galie N, Hinderliter AL, Torbicki A, et al: Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and doppler measures in patients with pulmonary arterial hypertension. J Am Coll Cardiol 2003; 41: 1380-1386.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1380-1386
    • Galie, N.1    Hinderliter, A.L.2    Torbicki, A.3
  • 49
    • 0344406959 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension
    • Barst RJ, Ivy D, Dingemanse J, et al: Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension. Clin Pharmacol Ther 2003; 73: 372-382.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 372-382
    • Barst, R.J.1    Ivy, D.2    Dingemanse, J.3
  • 50
    • 0035895324 scopus 로고    scopus 로고
    • Effectiveness of a nonselective ET(A/B) and a selective ET(A) antagonist in rats with monocrotaline-induced pulmonary hypertension
    • Jasmin JF, Lucas M, Cernacek P, Dupuis J: Effectiveness of a nonselective ET(A/B) and a selective ET(A) antagonist in rats with monocrotaline-induced pulmonary hypertension. Circulation 2001; 103: 314-318.
    • (2001) Circulation , vol.103 , pp. 314-318
    • Jasmin, J.F.1    Lucas, M.2    Cernacek, P.3    Dupuis, J.4
  • 51
    • 0141567469 scopus 로고    scopus 로고
    • Acute endothelin a receptor antagonism improves pulmonary and systemic haemodynamics in patients with pulmonary arterial hypertension that is primary or autoimmune and related to congenital heart disease
    • Apostolopoulou SC, Rammos S, Kyriakides ZS, et al: Acute endothelin A receptor antagonism improves pulmonary and systemic haemodynamics in patients with pulmonary arterial hypertension that is primary or autoimmune and related to congenital heart disease. Heart 2003; 89: 1221-1226.
    • (2003) Heart , vol.89 , pp. 1221-1226
    • Apostolopoulou, S.C.1    Rammos, S.2    Kyriakides, Z.S.3
  • 52
    • 0036283401 scopus 로고    scopus 로고
    • Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with pulmonary arterial hypertension: Open-label pilot study
    • Barst RJ, Rich S, Widlitz A, Horn EM, McLaughlin V, McFarlin J: Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with pulmonary arterial hypertension: open-label pilot study. Chest 2002; 121: 1860-1868.
    • (2002) Chest , vol.121 , pp. 1860-1868
    • Barst, R.J.1    Rich, S.2    Widlitz, A.3    Horn, E.M.4    McLaughlin, V.5    McFarlin, J.6
  • 53
    • 0030725503 scopus 로고    scopus 로고
    • ET(B) receptor and nitric oxide synthase blockade induce BQ-123-sensitive pressor effects in the rabbit
    • Gratton JP, Cournoyer G, Loffler BM, Sirois P, D'Orleans-Juste P: ET(B) receptor and nitric oxide synthase blockade induce BQ-123-sensitive pressor effects in the rabbit. Hypertension 1997; 30: 1204-1209.
    • (1997) Hypertension , vol.30 , pp. 1204-1209
    • Gratton, J.P.1    Cournoyer, G.2    Loffler, B.M.3    Sirois, P.4    D'Orleans-Juste, P.5
  • 54
    • 19444362442 scopus 로고    scopus 로고
    • Cardiovascular effects of sildenafil in experimental ischemia-reperfusion (reply to "Sildenafil-induced cardioprotection in rabbits, by Kukreja RC, Ockaili R, Salloum F, Xi L")
    • Reffelmann T, Kloner RA: Cardiovascular effects of sildenafil in experimental ischemia-reperfusion (reply to "Sildenafil-induced cardioprotection in rabbits, by Kukreja RC, Ockaili R, Salloum F, Xi L"). Cardiovasc Res 2003; 60: 702-703.
    • (2003) Cardiovasc Res , vol.60 , pp. 702-703
    • Reffelmann, T.1    Kloner, R.A.2
  • 55
    • 0035942990 scopus 로고    scopus 로고
    • Sildenafil inhibits hypoxia-induced pulmonary hypertension
    • Zhao L, Mason NA, Morrell NW, et al: Sildenafil inhibits hypoxia-induced pulmonary hypertension. Circulation 2001; 104: 424-428.
    • (2001) Circulation , vol.104 , pp. 424-428
    • Zhao, L.1    Mason, N.A.2    Morrell, N.W.3
  • 56
    • 0034241419 scopus 로고    scopus 로고
    • Sildenafil as a selective pulmonary vasodilator in childhood primary pulmonary hypertension
    • Abrams D, Schulze-Neick I, Magee AG: Sildenafil as a selective pulmonary vasodilator in childhood primary pulmonary hypertension. Heart 2000; 84: E4.
    • (2000) Heart , vol.84
    • Abrams, D.1    Schulze-Neick, I.2    Magee, A.G.3
  • 57
    • 0037152092 scopus 로고    scopus 로고
    • Sildenafil for treatment of lung fibrosis and pulmonary hypertension: A randomised controlled trial
    • Ghofrani HA, Wiedemann R, Rose F, et al: Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial. Lancet 2002; 360: 895-900.
    • (2002) Lancet , vol.360 , pp. 895-900
    • Ghofrani, H.A.1    Wiedemann, R.2    Rose, F.3
  • 58
    • 0037389118 scopus 로고    scopus 로고
    • Long-term treatment with oral Sildenafil in addition to continuous IV epoprostenol in patients with pulmonary arterial hypertension
    • Stiebellehner L, Petkov V, Vonbank K, et al: Long-term treatment with oral Sildenafil in addition to continuous IV epoprostenol in patients with pulmonary arterial hypertension. Chest 2003; 123:1293-1295.
    • (2003) Chest , vol.123 , pp. 1293-1295
    • Stiebellehner, L.1    Petkov, V.2    Vonbank, K.3
  • 59
    • 0036852964 scopus 로고    scopus 로고
    • Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension
    • Ghofrani HA, Rose F, Schermuly RT, et al: Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension. Crit Care Med 2002; 30: 2489-2492.
    • (2002) Crit Care Med , vol.30 , pp. 2489-2492
    • Ghofrani, H.A.1    Rose, F.2    Schermuly, R.T.3
  • 60
    • 0035845634 scopus 로고    scopus 로고
    • Effect of inhaled iloprost plus oral Sildenafil in patients with primary pulmonary hypertension
    • Wilkens H, Guth A, Konig J, et al: Effect of inhaled iloprost plus oral Sildenafil in patients with primary pulmonary hypertension. Circulation 2001; 104: 1218-1222.
    • (2001) Circulation , vol.104 , pp. 1218-1222
    • Wilkens, H.1    Guth, A.2    Konig, J.3
  • 61
    • 0036849571 scopus 로고    scopus 로고
    • Thrombopoietin inside the pulmonary vessels in patients with and without pulmonary hypertension
    • Haznedaroglu IC, Atalar E, Ozturk MA, et al: Thrombopoietin inside the pulmonary vessels in patients with and without pulmonary hypertension. Platelets 2002; 13: 395-399.
    • (2002) Platelets , vol.13 , pp. 395-399
    • Haznedaroglu, I.C.1    Atalar, E.2    Ozturk, M.A.3
  • 63
    • 0038369941 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension
    • Petkov V, Mosgoeller W, Ziesche R, et al: Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension. J Clin Invest 2003; 111: 1339-1346.
    • (2003) J Clin Invest , vol.111 , pp. 1339-1346
    • Petkov, V.1    Mosgoeller, W.2    Ziesche, R.3
  • 65
    • 0043204998 scopus 로고    scopus 로고
    • Arginine therapy: A new treatment for pulmonary hypertension in sickle cell disease?
    • Morris CR, Morris SM Jr, et al: Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease? Am J Respir Crit Care Med 2003; 168: 63-69.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 63-69
    • Morris, C.R.1    Morris Jr., S.M.2
  • 66
    • 0037421604 scopus 로고    scopus 로고
    • Signaling molecules in nonfamilial pulmonary hypertension
    • Du L, Sullivan CC, Chu D, et al: Signaling molecules in nonfamilial pulmonary hypertension. N Engl J Med 2003; 348: 500-509.
    • (2003) N Engl J Med , vol.348 , pp. 500-509
    • Du, L.1    Sullivan, C.C.2    Chu, D.3
  • 67
    • 0141679188 scopus 로고    scopus 로고
    • Expression of human herpesvirus 8 in primary pulmonary hypertension
    • Cool CD, Rai PR, Yeager ME, et al: Expression of human herpesvirus 8 in primary pulmonary hypertension. N Engl J Med 2003; 349: 1113-1122.
    • (2003) N Engl J Med , vol.349 , pp. 1113-1122
    • Cool, C.D.1    Rai, P.R.2    Yeager, M.E.3
  • 68
    • 0038143332 scopus 로고    scopus 로고
    • Association between hyperhomocysteinemia and primary pulmonary hypertension
    • Arroliga AC, Sandur S, Jacobsen DW, et al: Association between hyperhomocysteinemia and primary pulmonary hypertension. Respir Med 2003; 97: 825-829.
    • (2003) Respir Med , vol.97 , pp. 825-829
    • Arroliga, A.C.1    Sandur, S.2    Jacobsen, D.W.3
  • 69
    • 0037361583 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme DD genotype in patients with primary pulmonary hypertension: Increased frequency and association with preserved haemodynamics
    • Abraham WT, Raynolds MV, Badesch DB, et al: Angiotensin-converting enzyme DD genotype in patients with primary pulmonary hypertension: increased frequency and association with preserved haemodynamics. J Renin Angiotensin Aldosterone Syst 2003; 4: 27-30.
    • (2003) J Renin Angiotensin Aldosterone Syst , vol.4 , pp. 27-30
    • Abraham, W.T.1    Raynolds, M.V.2    Badesch, D.B.3
  • 70
    • 0033568512 scopus 로고    scopus 로고
    • Atrial septostomy as a bridge to lung transplantation in patients with severe pulmonary hypertension
    • Rothman A, Sklansky MS, Lucas VW, et al: Atrial septostomy as a bridge to lung transplantation in patients with severe pulmonary hypertension. Am J Cardiol 1999; 84: 682-686.
    • (1999) Am J Cardiol , vol.84 , pp. 682-686
    • Rothman, A.1    Sklansky, M.S.2    Lucas, V.W.3
  • 71
    • 0037274316 scopus 로고    scopus 로고
    • Atrial septostomy for severe primary pulmonary hypertension - Report on two cases
    • Kurzyna M, Dabrowski M, Torbicki A, et al: Atrial septostomy for severe primary pulmonary hypertension - report on two cases. Kardiol Pol 2003; 58: 27-33.
    • (2003) Kardiol Pol , vol.58 , pp. 27-33
    • Kurzyna, M.1    Dabrowski, M.2    Torbicki, A.3
  • 73
    • 0034817271 scopus 로고    scopus 로고
    • Atrial septostomy for pulmonary hypertension
    • Sandoval J, Rothman A, Pulido T: Atrial septostomy for pulmonary hypertension. Clin Chest Med 2001; 22: 547-560.
    • (2001) Clin Chest Med , vol.22 , pp. 547-560
    • Sandoval, J.1    Rothman, A.2    Pulido, T.3
  • 74
    • 0033822599 scopus 로고    scopus 로고
    • Indications for and the results of pulmonary thromboendarterectomy for thromboembolic pulmonary hypertension
    • Jamieson SW, Nomura K: Indications for and the results of pulmonary thromboendarterectomy for thromboembolic pulmonary hypertension. Semin Vase Surg 2000; 13: 236-244.
    • (2000) Semin Vase Surg , vol.13 , pp. 236-244
    • Jamieson, S.W.1    Nomura, K.2
  • 75
    • 0242721247 scopus 로고    scopus 로고
    • Pulmonary endarterectomy: Experience and lessons learned in 1,500 cases
    • discussion 1462-1464
    • Jamieson SW, Kapelanski DP, Sakakibara N, et al: Pulmonary endarterectomy: experience and lessons learned in 1,500 cases. Ann Thorac Surg 2003; 76:1457-1462; discussion 1462-1464.
    • (2003) Ann Thorac Surg , vol.76 , pp. 1457-1462
    • Jamieson, S.W.1    Kapelanski, D.P.2    Sakakibara, N.3
  • 76
    • 0037331512 scopus 로고    scopus 로고
    • Prostacyclin therapy before pulmonary thromboendarterectomy in patients with chronic thromboembolic pulmonary hypertension
    • Nagaya N, Sasaki N, Ando M, et al: Prostacyclin therapy before pulmonary thromboendarterectomy in patients with chronic thromboembolic pulmonary hypertension. Chest 2003; 123: 338-343.
    • (2003) Chest , vol.123 , pp. 338-343
    • Nagaya, N.1    Sasaki, N.2    Ando, M.3
  • 77
    • 0035168709 scopus 로고    scopus 로고
    • Lung transplantation for primary and secondary pulmonary hypertension
    • discussion 1679-1680
    • Conte JV, Borja MJ, Patel CB, Yang SC, Jhaveri RM, Orens JB: Lung transplantation for primary and secondary pulmonary hypertension. Ann Thorac Surg 2001; 72: 1673-1679; discussion 1679-1680.
    • (2001) Ann Thorac Surg , vol.72 , pp. 1673-1679
    • Conte, J.V.1    Borja, M.J.2    Patel, C.B.3    Yang, S.C.4    Jhaveri, R.M.5    Orens, J.B.6
  • 79
    • 0034307998 scopus 로고    scopus 로고
    • Ten years experience with lung and heart-lung transplantation in primary and secondary pulmonary hypertension
    • Franke U, Wiebe K, Harringer W, et al: Ten years experience with lung and heart-lung transplantation in primary and secondary pulmonary hypertension. Eur J Cardiothorac Surg 2000; 18: 447-452.
    • (2000) Eur J Cardiothorac Surg , vol.18 , pp. 447-452
    • Franke, U.1    Wiebe, K.2    Harringer, W.3
  • 81
    • 0035664496 scopus 로고    scopus 로고
    • Lung and heart-lung transplant practice patterns in pulmonary hypertension centers
    • Pielsticker EJ, Martinez FJ, Rubenfire M: Lung and heart-lung transplant practice patterns in pulmonary hypertension centers. J Heart Lung Transplant 2001; 20: 1297-1304.
    • (2001) J Heart Lung Transplant , vol.20 , pp. 1297-1304
    • Pielsticker, E.J.1    Martinez, F.J.2    Rubenfire, M.3
  • 82
    • 0034804729 scopus 로고    scopus 로고
    • Lung transplantation for primary pulmonary hypertension
    • Trulock EP: Lung transplantation for primary pulmonary hypertension. Clin Chest Med 2001; 22: 583-593.
    • (2001) Clin Chest Med , vol.22 , pp. 583-593
    • Trulock, E.P.1
  • 83
    • 0033551155 scopus 로고    scopus 로고
    • Long-term prostacyclin for pulmonary hypertension with associated congenital heart defects
    • Rosenzweig EB, Kerstein D, Barst RJ: Long-term prostacyclin for pulmonary hypertension with associated congenital heart defects. Circulation 1999; 99: 1858-1865.
    • (1999) Circulation , vol.99 , pp. 1858-1865
    • Rosenzweig, E.B.1    Kerstein, D.2    Barst, R.J.3
  • 84
    • 12844272424 scopus 로고    scopus 로고
    • Safety and tolerability of bosentan in adults with Eisenmenger physiology
    • Gatzoulis MA, Rogers P, Li W, et al: Safety and tolerability of bosentan in adults with Eisenmenger physiology, Int J Card 2005; 98: 147-151.
    • (2005) Int J Card , vol.98 , pp. 147-151
    • Gatzoulis, M.A.1    Rogers, P.2    Li, W.3
  • 85
    • 0036696142 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension in congenital heart disease
    • Granton JT, Rabinovitch M: Pulmonary arterial hypertension in congenital heart disease. Cardiol Clin 2002; 20: 441-457, vii.
    • (2002) Cardiol Clin , vol.20 , pp. 441-457
    • Granton, J.T.1    Rabinovitch, M.2


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