Targeted therapy with a cytotoxic somatostatin analog, AN-238, inhibits growth of human experimental endometrial carcinomas expressing multidrug resistance protein MDR-1

Cancer

Volumn 104, Issue 6, 2005, Pages 1312-1321

  Engel, Jorg B ^a,b   Schally, Andrew V ^a,b   Halmos, Gabor ^a,b   Baker, Ben ^a,b   Nagy, Attila ^a,b   Keller, Gunhild ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytotoxic conjugate AN 238; Endometrial carcinoma; Multidrug resistance; Somatostatin receptor; Targeted chemotherapy

Indexed keywords

2 PYRROLINODOXORUBICIN; ACETIC ACID; BREAST CANCER RESISTANCE PROTEIN; CYTOTOXIC AGENT; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLLYSYLVALYLCYSTEINYLTHREONINAMIDE 2,7 DISULFIDE; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLLYSYLVALYLCYSTEINYLTHREONINAMIDE 2,7 DISULFIDE 2 PYRROLINODOXORUBICIN; DOXORUBICIN DERIVATIVE; GLYCOPROTEIN; MANNITOL; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 2A; SOMATOSTATIN RECEPTOR 5; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CONJUGATE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG TARGETING; ENDOMETRIUM CARCINOMA; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR XENOGRAFT;

AGED; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE, TUMOR; DOXORUBICIN; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; MICE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; P-GLYCOPROTEIN; PYRROLES; RECEPTORS, SOMATOSTATIN; RNA, MESSENGER; SOMATOSTATIN; TRANSPLANTATION, HETEROLOGOUS;

EID: 24644445086     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.21327     Document Type: Article

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