Influence of ultra-endurance exercise on immunoglobulin isotypes and subclasses

British Journal of Sports Medicine

Volumn 39, Issue 9, 2005, Pages 665-670

  McKune, A J ^a   Smith, L L ^a   Semple, S J ^a   Wadee, A A ^b  

^a TSHWANE UNIVERSITY OF TECHNOLOGY   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M; IMMUNOGLOBULIN SUBCLASS;

ADAPTATION; ADAPTIVE IMMUNITY; ADULT; ANTIBODY RESPONSE; ARTICLE; ENDURANCE; EXERCISE; FEMALE; HEALTH; HUMAN; IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATION; INNATE IMMUNITY; ISOTYPE SWITCHING; MALE; MARATHON RUNNER; NORMAL HUMAN; TISSUE INJURY; ULTRA ENDURANCE EXERCISE; UPPER RESPIRATORY TRACT INFECTION;

ADULT; BODY COMPOSITION; EXERCISE; FEMALE; HEART RATE; HUMANS; IMMUNOGLOBULIN ISOTYPES; MALE; MIDDLE AGED; OXYGEN CONSUMPTION; PHYSICAL ENDURANCE; RUNNING;

EID: 24644431575     PISSN: 03063674     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjsm.2004.017194     Document Type: Article

References (38)

1. Nieman D, Johanssen LM, Lee JW. Infectious episodes in runners before and after the Los Angeles Marathon. J Sportsmed Phys Fitness 1990;30:316-28.
2. Peters EM, Bateman ED. Ultramarathon running and upper respiratory tract infections: an epidemiological study. S Afr Med J 1983;64:582-4.
3. Smith LL. An alternate approach to assessing immune function related to upper respiratory tract infection (URTI). Int SportMed J 2003;4:1-9.
4. Smith LL. Overtraining, excessive exercise, and altered immunity: is this a T helper-1 versus T helper-2 lymphocyte response? Sports Med 2003;33:347-64.
5. Ceddia AAA, Woods JA. Exercise suppresses macrophage antigen presentation. J Appl Physiol 1999;87:2253-8.
6. Pedersen BK, Ullum H. NK cell response to physical activity: possible mechanisms of action. Med Sci Sports Exerc 1994;26:140-6.
7. Kendall A, Hoffman-Goetz L, Houston M, et al. Exercise and blood lymphocyte subset responses: intensity, duration, and subject fitness effects. J Appl Physiol 1990;69:251-60.
8. Shephard RJ, Rhind S, Shek PN. Exercise and training: influences on cytotoxicity, interleukin-1, interleukin-2 and receptor structures. Int J Sports Med 1994;15:154-66.
9. Roitt I, Brostoff J, Male D. Immunology, 6th ed. Edinburgh: Mosby, 2001.
10. Crotty S, Ahmed R. Immunological memory in humans. Semin Immunol 2004;16:197-203.
11. Boes M. Role of natural and immune IgM antibodies in immune responses. Mol Immunol 2000;37:1141-9.
12. Janeway CA, Travers P, Walport M, et al. Immunobiology: the immune system in health and disease, 5th ed. New York: Garland Publishing, 2001.
13. Nieman DC, Tan SA, Lee JW, et al. Complement and immunoglobulin levels in athletes and sedentary controls. Int J Sports Med 1989;10:124-8.
14. Nieman DC, Nehlsen-Cannarella SL. The effects of acute and chronic exercise and immunoglobulins. Sports Med 1991;11:183-201.
15. Nehlsen-Cannarella SL, Nieman DC, Jessen J, et al. The effects of acute moderate exercise on lymphocyte function and serum immunoglobulin levels. Int J Sports Med 1991;12:391-8.
16. Petibois C, Cazorla G, Deleris G. The biological and metabolic adaptations to 12 months training in elite rowers. Int J Sports Med 2003;24:36-42.
17. Mackinnon LT, Hooper SL. Mucosal (secretory) immune system responses to exercise of varying intensity and during overtraining. Int J Sports Med 1994;15:S179-83.
18. Mashiko T, Umeda T, Nakaji S, et al. Effects of exercise on the physical condition of college rugby players during summer training camp. Br J Sports Med 2004;38:186-90.
19. Ross WD, Wilson NC. Growth and development. A stratagem for propotional growth assessment. Acta Paediatr Belg 1974;24:169-82.
20. Mars M, Govender S, Weston A, et al. High intensity exercise: a cause of lymphocyte apoptosis? Biochem Biophys Res Commun 1998;249:366-70.
21. Powers SK, Howley ET. Exercise physiology: theory and application to fitness and performance, 4th ed. New York: McGraw-Hill Higher Education, 2001.
22. Peters EM, Goetzsche JM, Grobbelaar B, et al. Vitamin C supplementation reduces the incidence of postrace symptoms of upper-respiratory-tract infection in ultramarathon runners. Am J Clin Nutr 1993;57:170-4.
23. Dill DB, Costill DL. Calculation of percentage changes of blood, plasma and red cells in dehydration. J App Physiol 1974;37:247-8.
24. Mackinnon LT. Advances in exercise immunology. Torrens Park, South Australia: Human Kinetics, 1999.
25. Ohlin M, Zouali M. The human antibody repertoire to infectious agents: implications for disease pathogenesis. Mol Immunol 2003;40:1-11.
26. Poortmans JR. Serum protein determination during short exhaustive physical activity. J Appl Physiol 1971;30:190-2.
27. Poortmans JR, Haralambie G. Biochemical changes in a 100 km run: proteins in serum and urine. Eur J Physiol 1979;40:245-54.
28. Israel S, Buhl B, Neumann G. Die konzentration der immunglobuline A, G und M im serum bei trainierten und untrainierten sowie nach verschiedenen sportlicken ausdauerleistungen. Med Sport (Berlin) 1982;22:225-31.
29. Coffman RL, Lebman DA, Rothman P. Mechanism and regulation of immunoglobulin isotype switching. Adv Immunol 1993;54:229-70.
30. Elenkov IJ, Wilder RL, Chrousos GP, et al. The sympathetic nerve: an integrative interface between two supersystems: the brain and the immune system. Pharmacol Rev 2000;52:595-638.
31. Roitt I. Essential immunology, 8th ed. Oxford: Blackwell Science, 1994.
32. Hanson PG, Flaherty DK. Immunological responses to training in conditioned runners. Clin Sci 1981;60:225-8.
33. Gmûnder FK, Joller PW, Joller-Jemelka HI, et al. Effect of a herbal yeast food supplement and long-distance running on immunological parameters. Br J Sports Med 1990;24:103-12.
34. Romagnani S. The Th1/Th2 paradigm and allergic disorders. Allergy 1998;53(suppl 46):12-15.
35. Gleeson M. Mucosal immunity and respiratory illness in elite athletes. Int J Sports Med 2000;21(suppl 1):S33-43.
36. Stavnezer J. Immunlglobulin class switching. Curr Opin Immunol 1996;8:199-205.
37. Whitham M, Blannin AK. The effect of exercise training on the kinetics of the antibody response to influenza vaccination. J Sports Sci 2003;21:991-1000.
38. Smith TP, Kennedy SL, Fleshner M. Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men. J Appl Physiol 2004;97:491-8.