The lysosomal degradation of neuromedin B is dependent on tripeptidyl peptidase-I: Evidence for the impairment of neuropeptide degradation in late-infantile neuronal ceroid lipofuscinosis

Biochemical and Biophysical Research Communications

Volumn 319, Issue 1, 2004, Pages 58-65

  Kopan, Sharmila ^a   Sivasubramaniam, Uthayatharsini ^a   Warburton, Michael J ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Lysosome; Neuromedin B; Neuronal ceroid lipofuscinosis; Neuropeptide degradation; Tripeptidyl peptidase I

Indexed keywords

NEUROMEDIN B; NEUROPEPTIDE; PEPTIDASE; PEPTIDE HYDROLASE INHIBITOR; TRIPEPTIDYL PEPTIDASE I; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL CULTURE; CELL TYPE; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; LYSOSOME; MOUSE; NEURONAL CEROID LIPOFUSCINOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; BRAIN; CELL LINE; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENDOPEPTIDASES; FIBROBLASTS; HUMANS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; NEUROKININ B; NEURONS; PEPTIDE HYDROLASES; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; SKIN; TIME FACTORS;

EID: 2442707527     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.04.142     Document Type: Article

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