Microarray gene analysis of the liver in a rat model of chronic, voluntary alcohol intake

Alcohol

Volumn 32, Issue 2, 2004, Pages 113-127

  Deaciuc, Ion V ^a,c   Peng, Xuejun ^b   D'Souza, Nympha B ^a   Shedlofsky, Steven I ^a   Burikhanov, Ravshan ^a   Voskresensky, Igor V ^a   De Villiers, Willem J S ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c University of Louisville School of Medicine   (United States)

Author keywords

DNA microarray; Gene expression; Lipopolysaccharide

Indexed keywords

ALCOHOL; BACTERIUM LIPOPOLYSACCHARIDE; LIVER ENZYME; RNA;

ALCOHOL CONSUMPTION; ALCOHOL LIVER DISEASE; ALCOHOLISM; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD SAMPLING; CONTROLLED STUDY; DIET; DISEASE MODEL; DNA MICROARRAY; ENZYME ACTIVITY; ENZYME ASSAY; ESCHERICHIA COLI; GENE EXPRESSION; GENETIC ANALYSIS; HISTOPATHOLOGY; LIVER INJURY; LIVER TOXICITY; LONG TERM EXPOSURE; MALE; MEDIATOR; NONHUMAN; RAT; REVIEW; RNA ANALYSIS; RNA EXTRACTION; UNINDEXED SEQUENCE;

ESCHERICHIA COLI;

EID: 2442706970     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.alcohol.2003.12.001     Document Type: Article

References (35)

1. Asch A.S., Barnwell J., Siverstein R.L., Nachman R.L. Isolation of thrombospondin receptor. J Clin Invest. 79:1987;1054-1061
2. Bjarnason I., Peters T.J., Wise R.J. The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet. 1:1984;179-182
3. Bode J.C., Bode C., Heidelbach R., Durr H.K., Martini G.A. Jejunal microflora in patients with chronic alcohol abuse. Hepatogastroenterology. 31:1984;30-34
4. Bulera S.J., Eddy S.M., Ferguson E., Jatkoe T.A., Reindel J.F., Bleavins M.R., De La Iglesia F.A. RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays. Hepatology. 33:2001;1239-1258
5. Casini A., Galli G., Salzano R., Ceni E., Franceschelli F., Rotella C.M., Surrenti C. Acetaldehyde induces c-fos and c-jun proto-oncogenes in fat-storing cell cultures through protein kinase C activation. Alcohol Alcohol. 29:1994;303-314
6. Deaciuc I.V. Alcohol and cytokine networks. Alcohol. 14:1997;421-430
7. Deaciuc I.V., D'Souza N.B., de Villiers W.J., Burikhanov R., Sarphie T.G., Hill D.B., McClain C.J. Inhibition of caspases in vivo protects the rat liver against alcohol-induced sensitization to bacterial lipopolysaccharide. Alcohol Clin Exp Res. 25:2001;935-943
8. Deaciuc I.V., Fortunato F., D'Souza N.B., Hill D.B., Schmidt J., Lee E.Y., McClain C.J. Modulation of caspase-3 activity and Fas ligand mRNA expression in rat liver cells in vivo by alcohol and lipopolysaccharide. Alcohol Clin Exp Res. 23:1999;349-356
9. 4 intoxication in the rat. Hepatology. 23:1996;1530-1537
10. French S.W. Intragastric ethanol infusion model for cellular and molecular studies of alcoholic liver disease. J Biomed Sci. 8:2001;20-27
11. Goldin R. Rodent models of alcoholic liver disease. Int J Exp Pathol. 75:1994;1-7
12. Gordon A.S., Collier K., Diamond I. Ethanol regulation of adenosine receptor-stimulated cAMP levels in a clonal neural cell line: an in vitro model of cellular tolerance to ethanol. Proc Natl Acad Sci U S A. 83:1986;2105-2108
13. Hardardottir I., Grunfeld C., Feingold K.R. Effects of endotoxin and cytokines on lipid metabolism. Curr Opin Lipidol. 5:1994;207-215
14. Hoek J.B., Taraschi T.F., Rubin E. Functional implications of the interaction of ethanol with biologic membranes: actions of ethanol on hormonal signal transduction systems. Semin Liver Dis. 8:1988;36-46
15. Hoek J.B., Thomas A.P., Rooney T.A., Higashi K., Rubin E. Ethanol and signal transduction in the liver. FASEB J. 6:1992;2386-2396
16. L proteins. Oncogene. 21:2002;32-43
17. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council. Guide for the Care and Use of Laboratory Animals. 1996;National Academy Press, Washington, DC
18. Järveläinen H.A., Fang C., Ingelman-Sundberg M., Lindros K.O. Effect of chronic coadministration of endotoxin and ethanol on rat liver pathology and proinflammatory and anti-inflammatory cytokines. Hepatology. 29:1999;1503-1510
19. Koteish A., Yang S., Lin H., Huang X., Diehl A.M. Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation. J Biol Chem. 277:2002;13037-13044
20. αsmessenger RNA. Nature. 333:1988;848-850
21. Morimoto M., Hagbjörk A.L., Nanji A.A., Ingelman-Sundberg M., Lindros K.O., Fu P.C., Albano E., French S.W. Role of cytochrome P4502E1 in alcoholic liver disease pathogenesis. Alcohol. 10:1993;459-464
22. Nakamura M.T., Tang A.B., Villanueva J., Halsted C.H., Phinney S.D. Selective reduction of Δ6 and Δ5 desaturase activities but not Δ9 desaturase in micropigs chronically fed ethanol. J Clin Invest. 93:1994;450-454
23. Nervi A.M., Peluffo R.O., Brenner R.R., Leikin A.I. Effect of ethanol administration on fatty acid desaturation. Lipids. 15:1980;263-268
24. 2 and cyclooxygenase-2. J Biol Chem. 275:2000;20136-20145
25. Ronis M.J., Huang J., Crouch J., Mercado C., Irby D., Valentine C.R., Lumpkin C.K., Ingelman-Sundberg M., Badger T.M. Cytochrome P450 CYP 2E1 induction during chronic alcohol exposure occurs by a two-step mechanism associated with blood alcohol concentrations in rats. J Pharmacol Exp Ther. 264:1993;944-950
26. Sato T., Aoki J., Nagai Y., Dohmae N., Takio K., Doi T., Arai H., Inoue K. Serine-phospholipid-specific phospholipase A that is secreted from activated platelets. A new member of the lipase family. J Biol Chem. 272:1997;2192-2198
27. Tadic S.D., Elm M.S., Li H.S., Van Londen G.J., Subbotin V.M., Whitcomb D.C., Eagon P.K. Sex differences in hepatic gene expression in a rat model of ethanol-induced liver injury. J Appl Physiol. 93:2002;1057-1068
28. Takase S., Takada A., Urashima S., Enyama K., Fujii M. Changes in the markers related to collagen synthesis in the liver of chronically alcohol treated rats. Gastroenterol Jpn. 27:1992;54-60
29. Tandon N.N., Kralisz U., Jamieson G.A. Identification of glycoprotein IV (CD36) as a primary receptor for platelet-collagen adhesion. J Biol Chem. 264:1989;7576-7583
30. Thurman R.G. Mechanisms of hepatic toxicity II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin. Am J Physiol Gastrointest Liver Physiol. 275:1998;G605-G611
31. Vara E., Arias-Diaz J., Torres-Melero J., Garcia C., Rodriguez J.M., Balibrea J.L. Effect of different sepsis-related cytokines on lipid synthesis by isolated hepatocytes. Hepatology. 20:1994;924-931
32. Villanueva J., Chandler C.J., Shimasaki N., Tang A.B., Nakamura M., Phinney S.D., Halsted C.H. Effects of ethanol feeding on liver, kidney and jejunal membranes of micropigs. Hepatology. 19:1994;1229-1240
33. Waladkhani A., Clemens M., Bode J.C., Bode C. Effect of methionine on the fatty acid composition of cellular membranes in rats with chronic ethanol consumption and jejunoileal bypass. Alcohol Alcohol. 31:1996;463-469
34. Yacoub L.K., Fogt F., Griniuviene B., Nanji A.A. Apoptosis and bcl-2 protein expression in experimental alcoholic liver disease in the rat. Alcohol Clin Exp Res. 19:1995;854-859
35. Zern M.A., Leo M.A., Giambrone M.A., Lieber C.S. Increased type I procollagen mRNA levels and in vitro protein synthesis in the baboon model of chronic alcoholic liver disease. Gastroenterology. 89:1985;1123-1131