Asymmetric addition of KCN and Ac2O to aldehydes catalyzed by recyclable polymeric salen-Ti(IV) complexes

Tetrahedron Letters

Volumn 45, Issue 24, 2004, Pages 4763-4767

  Huang, Wei ^a   Song, Yuming ^a   Bai, Changmin ^a   Cao, Guoying ^a   Zheng, Zhuo ^a  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

Aldehyde; Asymmetric cyanation; O Acetyl cyanohydrins; Potassium cyanide; Recyclable polymeric salen Ti(IV) complexes

Indexed keywords

ACETIC ACID DERIVATIVE; ALDEHYDE; POLYMER; POTASSIUM CYANIDE; TITANIUM DERIVATIVE;

ADDITION REACTION; ARTICLE; CATALYST; CROSS LINKING; CYANATION; ENANTIOSELECTIVITY; GAS CHROMATOGRAPHY;

EID: 2442701280     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.04.086     Document Type: Article

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26. The polymeric salen-Ti(IV) complexes (5/6=25/100), which is partly soluble in the reaction system, was employed and could be precipitated completely from the reaction mixture by the addition of hexane. It was very important that the recovered catalyst must be washed thoroughly with water, otherwise, obviously decreased conversion and ee value were observed. However, the catalyst 1 showed good solubility in hexane and could not be recovered efficiently