32P-postlabeling of DNA adducts arising from complex mixtures: HPLC versus TLC separation applied to adducts from petroleum products

Archives of Toxicology

Volumn 78, Issue 3, 2004, Pages 174-181

  Eriksson, Hanna L ^a   Zeisig, Magnus ^a   Ekström, Lars Gösta ^b   Möller, Lennart ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Group Competence Centre   (Sweden)

Author keywords

32P HPLC; 32P Postlabeling; DNA adducts; Petroleum; Polycyclic aromatic compounds

Indexed keywords

PETROLEUM; PETROLEUM DERIVATIVE; PHOSPHORUS 32; CALF THYMUS DNA; DNA; MUTAGENIC AGENT; PHOSPHORUS;

ACCURACY; ARTICLE; CARCINOGENIC ACTIVITY; DNA ADDUCT; GENOTOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; ISOTOPE LABELING; MUTAGENIC ACTIVITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; THIN LAYER CHROMATOGRAPHY; CHEMISTRY; COMPARATIVE STUDY; DNA DAMAGE; DRUG EFFECT; DRUG MIXTURE; METABOLISM; METHODOLOGY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; COMPLEX MIXTURES; DNA; DNA ADDUCTS; DNA DAMAGE; MUTAGENS; PETROLEUM; PHOSPHORUS RADIOISOTOPES;

EID: 2442695161     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-003-0520-5     Document Type: Article

References (35)

1. 32P-HPLC. Arch Toxicol 74:720-731 [Erratum, Arch Toxicol 75:123-125]
2. 32P-postlabeling assay. Carcinogenesis 13:1053-1074
3. Beland FA, Kadlubar FF (1985) Formation and persistence of aryl-amine DNA adducts in vivo. Environ Health Perspect 62:19-30
4. Blackburn GR, Roy TA, Bleicher WT, Reddy MV, Mackerer CR (1996) Comparison of biological and chemical predictors of dermal carcinogenicity of petroleum oils. Polycyclic Aromatic Compounds 11:201-210
5. 32P-postlabeling-detection of DNA adducts in mouse skin in vivo with the polycyclic aromatic compound content and mutagenicity in Salmonella typhimurium of a range of oil products. Arch Toxicol 72:505-513
6. 32P-HPLC method. Biomarkers 5:182-191
7. Cui XS, Torndal UB, Eriksson LC, Möller L (1995) Early formation of DNA adducts compared with tumor formation in a long-term study in rats after administration of 2-nitrofluorene. Carcinogenesis 16:2135-2141
8. Dale CM, Garner RC (1996) Measurement of DNA adducts in humans after complex mixture exposure. Food Chem Toxicol 34:905-919
9. 32P-postlabeling assay for DNA adduct induction. J Appl Toxicol 17:113-117
10. Dipple A, Pigott MA, Bigger CA, Blake DM (1984) 7,12-dimethylbenz[a] anthracene DNA binding in mouse skin: response of different mouse strains and effects of various modifiers of carcinogenesis. Carcinogenesis 5:1087-1090
11. Dipple A, Pigott MA, Agarwal SK, Yagi H, Sayer JM, Jerina DM (1987) Optically active benzo[c]phenanthrene diol epoxides bind extensively to adenine in DNA. Nature 327:535-536
12. Garner RC (1998) The role of DNA adducts in chemical carcinogenesis. Mutat Res 402:67-75
13. 32P-postlabeling analysis of aromatic carcinogen: DNA adducts. Cancer Res 45:5656-5662
14. 32P-Postlabeling analysis of nonradioactive aromatic carcinogen-DNA adducts. Carcinogenesis 12:1081-1092
15. Hemminki K (1993) DNA adducts, mutations and cancer. Carcinogenesis 14:2007-2012
16. IARC (International Agency for Reseach on Cancer) (1989) Monographs on the evaluation of Carcinogenic risks to humans, Vol 45. Occupational exposures in petroleum refining; crude oil and major petroleum fuels. IARC Press, Lyon, p 119
17. 32P-postlabelling: is adduct formation truly indicative of carcinogenic potential? J Appl Toxicol 15:275-283
18. Ingram AJ, Phillips JC, Davies S (2000) DNA adducts produced by oils, oil fractions and polycyclic aromatic hydrocarbons in relation to repair processes and skin carcinogenesis. J Appl Toxicol 20:165-174
19. 32P-postlabelling assay using different chromatographic techniques. J Chromatogr B Biomed Sci Appl 691:155-160
20. Maron DM, Ames BN (1983) Revised methods for Salmonella mutagenicity test. Mutat Res 113:173-215
21. 32P-postlabeled DNA adducts. Carcinogenesis 14:1343-1348
22. 32P-HPLC. Carcinogenesis 17:61-66
23. 32P-labelled nucleoside 3′,5′-bisphosphate adducts of polycyclic aromatic hydrocarbons. J Chromatogr 570:65-76
24. Phillips DH, Castegnaro M, Bartch H (eds) (1993) IARC Scientific Publication 124. Postlabeling methods for detection of DNA adducts. International Agency for Research on Cancer, Lyon
25. Phillips DH, Farmer PB, Beland FA, Nath RG, Poirier MC, Reddy MV, Turteltaub KW (2000) Methods of DNA adduct determination and their application to testing compounds for genotoxicity. Environ Mol Mutagen 35:222-233
26. Poirier MC, Santella RM, Weston A (2000) Carcinogen macromolecular adducts and their measurement. Carcinogenesis 21:353-359
27. 32P-labeling test for DNA damage. Proc Natl Acad Sci USA 78:6126-6129
28. 32P-postlabeling analysis of exogenous and endogenous DNA adducts in mouse skin exposed to a wood-preserving waste extract, a complex mixture of polycyclic and polychlorinated chemicals. Environ Mol Mutagen 29:372-378
29. Reddy MV, Blackburn GR, Schreiner CA, Mackerer CR (1997) Correlation of mutagenic potencies of various petroleum oils and coal tar mixtures with DNA adduct levels in vitro. Mutat Res 378:89-95
30. Roy TA, Johnson SW, Blackburn GR, Mackerer CR (1988) Correlation of mutagenic and dermal carcinogenic activities of mineral oils with polycyclic aromatic compound content. Fundam Appl Toxicol 10:466-476
31. Srám RJ, Binková B (2000) Molecular epidemiology studies on occupational and environmental exposure to mutagens and carcinogens, 1997-1999. Environ Health Perspect 108: 57-70
32. 32P-postlabelling and subsequent thin-layer and high-pressure liquid chromatography. Carcinogenesis 11:639-646
33. 32P-postlabeling analysis of DNA adducts from non-alternant PAH using thin-layer and high performance liquid chromatography. Cancer Lett 37:257-266
34. 32P-Postlabeling high-performance liquid chromatographic improvements to characterize DNA adduct stereoisomers from benzo[a]pyrene and benzo[c]phenanthrene, and to separate DNA adducts from 7,12-dimethylbenz[a]anthracene. J Chromatogr B Biomed Sci Appl 691:341-350
35. 32P-HPLC) adapted for analysis of 8-hydroxy-2′-deoxyguanosine. Carcinogenesis 7:1241-1245