KATP channel knockout mice crossbred with transgenic mice expressing a dominant-negative form of human insulin receptor have glucose intolerance but not diabetes

Endocrine Journal

Volumn 51, Issue 2, 2004, Pages 133-144

  Kanezaki, Yoshiko ^a,b   Obata, Toshiyuki ^a   Matsushima, Rie ^a,b   Minami, Asako ^a   Yuasa, Tomoyuki ^a   Kishi, Kazuhiro ^a   Bando, Yoshimi ^b   Uehara, Hisanori ^b   Izumi, Keisuke ^b   Mitani, Tasuku ^a   Matsumoto, Mitsuru ^a   Takeshita, Yukari ^b   Nakaya, Yutaka ^b   Matsumoto, Toshio ^b   Ebina, Yousuke ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Diabetes mellitus; Impaired insulin secretion; Insulin resistance; KATP channel knockout mouse; Tyrosine kinase deficient insulin receptor transgenic mouse

Indexed keywords

ADENOSINE TRIPHOSPHATE; INSULIN RECEPTOR; POTASSIUM CHANNEL; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CROSS BREEDING; DIABETES MELLITUS; ENZYME DEFICIENCY; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; INSULIN RESISTANCE; KNOCKOUT MOUSE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; ENZYME ACTIVATION; EPIDIDYMIS; FASTING; GENES, DOMINANT; GENOTYPE; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; LEPTIN; LIVER; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; ORGAN SIZE; POSTPRANDIAL PERIOD; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN;

EID: 2442661263     PISSN: 09188959     EISSN: None     Source Type: Journal    
DOI: 10.1507/endocrj.51.133     Document Type: Article

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