Crystal Structure of an Aspartate Aminotransferase (TM1255) from Thermotoga maritima at 1.90 Å Resolution

Proteins: Structure, Function and Genetics

Volumn 55, Issue 3, 2004, Pages 759-763

  Schwarzenbacher, Robert ^a,d   Jaroszewski, Lukasz ^a,d   Von Delft, Frank ^a,f   Abdubek, Polat ^a,c   Ambing, Eileen ^a,c   Biorac, Tanja ^a,c   Brinen, Linda S ^a,b   Canaves, Jaume M ^a,d   Cambell, Jamison ^a,c   Chiu, Hsui Ju ^a,c   Dai, Xiaoping ^a,f   Deacon, Ashley M ^a,b   DiDonato, Mike ^a,c   Elsliger, Marc André ^a,f   Eshagi, Said ^a,c   Floyd, Ross ^a,b   Godzik, Adam ^a,d   Grittini, Carina ^a,f   Grzechnik, Slawomir K ^a,d   Hampton, Eric ^a,c   Karlak, Cathy ^a,c   Klock, Heath E ^a,c   Koesema, Eric ^a,c   Kovarik, John S ^a,b   Kreusch, Andreas ^a,c   Kuhn, Peter ^a,b   Lesley, Scott A ^a,c   Levin, Inna ^a,b   McMullan, Daniel ^a,c   McPhillips, Timothy M ^a,b   Miller, Mitchell D ^a,b   Morse, Andrew ^a,d   Moy, Kin ^a,f   Ouyang, Jie ^a,d   Page, Rebecca ^a,f   Quijano, Kevin ^a,c   Robb, Alyssa ^a,c   Spraggon, Glen ^a,c   Stevens, Raymond C ^a,f   Van Den Bedem, Henry ^a,b   Velasquez, Jeff ^a,f   Vincent, Juli ^a,c   Wang, Xianhong ^a,d   West, Bill ^a,d   Wolf, Guenter ^a,b   Xu, Qingping ^a,b   Hodgson, Keith O ^a,b   Wooley, John ^a,d,e   Wilson, Ian A ^a,f   more..

^a Joint Center for Structural Genomics   (United States)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^c GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; PROTEIN TM1255; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BACTERIAL GENE; BETA SHEET; CATALYSIS; CRYSTAL STRUCTURE; CRYSTALLIZATION; ISOELECTRIC POINT; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN DEGRADATION; THERMOTOGA MARITIMA;

AMINO ACID SEQUENCE; ASPARTATE AMINOTRANSFERASES; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; THERMOTOGA MARITIMA;

BACTERIA (MICROORGANISMS); THERMOTOGA; THERMOTOGA MARITIMA;

EID: 2442621521     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10646     Document Type: Article

References (18)

1. Braunstein AE, Goryachenkova EV. The pyridoxal-phosphate-dependent enzymes exclusively catalyzing reactions of beta-replacement. Biochimie 1976;58:5-17.
2. Malashkevich VN, Toney MD, Jansonius JN. Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase. Biochemistry 1993;32: 13451-13462.
3. Okamoto A, Kato R, Masui R, Yamagishi A, Oshima T, Kuramitsu S. An aspartate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8. J Biochem (Tokyo) 1996; 119:135-144.
4. Rhee S, Silva MM, Hyde CC, Rogers PH, Metzler CM, Metzler DE, Arnone A. Refinement and comparisons of the crystal structures of pig cytosolic aspartate aminotransferase and its complex with 2-methylaspartate. J Biol Chem 1997;272:17293-17302.
5. Nakai T, Okada K, Akutsu S, Miyahara I, Kawaguchi S, Kato R, Kuramitsu S, Hirotsu K. Structure of Thermus thermaphilus HB8 aspartate aminotransferase and its complex with maleate. Biochemistry 1999;38:2413-2424.
6. Lesley SA, Kuhn P, Godzik A, Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Wooley J, Taylor SS, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci USA 2002;99:11664-11669.
7. Laskowski RA, MacArthur MW, Moss DS, Thornton JM. PRO-CHECK: a program to check the stereochemical quality of protein structures. J Appl Crystallogr 1993;26:283-291.
8. Murzin AG, Brenner SE, Hubbard T, Chothia C. SCOP: a structural classification of proteins database for the investigation of sequences and structures. J Mol Biol 1995;247:536-540.
9. Holm L, Sander C. DALI: A network tool for protein structure comparison. Trends Biochem Sci 1995;20:478-480.
10. Jaroszewski L, Li W, Godzik A. In search for more accurate alignments in the twilight zone. Protein Sci 2002;11:1702-1713.
11. Santarsiero BD, Yegian DT, Lee CC, Spraggon G, Gu J, Scheibe D, Uber DC, Cornell EW, Nordmeyer RA, Kolbe WF, Jin J, Jones AL, Jaklevic JM, Schultz PG, Stevens RC. An approach to rapid protein crystallization using nanodroplets. J Appl Crystallogr 2002;35:278-281.
12. McPhillips TM, McPhillips SE, Chiu HJ, Cohen AE, Deacon AM, Ellis PJ, Garman E, Gonzalez A, Sauter NK, Phizackerley RP, Soltis SM, Kuhn P. Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines. J Synchrotron Radiat 2002;9: 401-406.
13. Leslie AGW. Recent changes to the MOSFLM package for processing film. and image plate data Joint CCP4 + ESF-EAMCB Newsletter on Protein Crystallography 1992;26.
14. Collaborative Computational Project Number 4. The CCP4 Suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr 1994;50:760-763.
15. Vriend GJ. WHATIF: a molecular modeling and drug design program. Mol Graph 1990;8:52-56.
16. Jones TA, Zou J-Y, Cowan SW, Kjeldaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr D Biol Crystallogr 1991;47:110-119.
17. McRee DE. XtalView/Xfit-a versatile program for manipulating atomic coordinates and electron density. J Struct Biol 1999;125: 156-165.
18. Tickle IJ, Laskowski RA, Moss DS. Error estimates of protein structure coordinates and deviations from standard geometry by full-matrix refinement of gammaB- and betaB2-crystallin. Acta Crystallogr D Biol Crystallogr 1998;54:243-252.