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Volumn 150, Issue 2, 2004, Pages 117-124

Vitamin E amelioration of ethanol neurotoxicity involves modulation of apoptotis-related protein levels in neonatal rat cerebellar granule cells

Author keywords

Tocopherol; Antioxidant; Apoptosis; Bcl 2; Disorders of the nervous system; Ethanol; Neurotoxicity; Vitamin E

Indexed keywords

ALCOHOL; ALPHA TOCOPHEROL; PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BCL XS; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 2442582391     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devbrainres.2004.03.010     Document Type: Article
Times cited : (39)

References (33)
  • 1
    • 0033519552 scopus 로고    scopus 로고
    • The effect of ethanol on lipid peroxidation and glutathione level in the brain stem of rat
    • Agar E., Bosnak M., Amanvermez R., Demir S., Ayyildiz M., Celik C. The effect of ethanol on lipid peroxidation and glutathione level in the brain stem of rat. NeuroReport. 10:1999;1799-1801
    • (1999) NeuroReport , vol.10 , pp. 1799-1801
    • Agar, E.1    Bosnak, M.2    Amanvermez, R.3    Demir, S.4    Ayyildiz, M.5    Celik, C.6
  • 2
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., Greenberg M.E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91:1997;231-241
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 3
    • 0034128363 scopus 로고    scopus 로고
    • Partial rescue of ethanol-induced neuronal apoptosis by growth factor activation of phosphoinositol-3-kinase
    • de la Monte S.M., Ganju N., Banerjee K., Brown N.V., Luong T., Wands J.R. Partial rescue of ethanol-induced neuronal apoptosis by growth factor activation of phosphoinositol-3-kinase. Alcohol., Clin. Exp. Res. 24:2000;716-726
    • (2000) Alcohol., Clin. Exp. Res. , vol.24 , pp. 716-726
    • De La Monte, S.M.1    Ganju, N.2    Banerjee, K.3    Brown, N.V.4    Luong, T.5    Wands, J.R.6
  • 5
    • 0037735348 scopus 로고    scopus 로고
    • Vitamin e therapy in Parkinson's disease
    • Fariss M.W., Zhang J.G. Vitamin E therapy in Parkinson's disease. Toxicology. 189:2003;129-146
    • (2003) Toxicology , vol.189 , pp. 129-146
    • Fariss, M.W.1    Zhang, J.G.2
  • 6
    • 0037265851 scopus 로고    scopus 로고
    • Vitamin e blocks early events induced by 1-methyl-4-phenylpyridinium (MPP+) in cerebellar granule cells
    • Gonzalez-Polo R.A., Soler G., Alvarez A., Fabregat I., Fuentes J.M. Vitamin E blocks early events induced by 1-methyl-4-phenylpyridinium (MPP+) in cerebellar granule cells. J. Neurochem. 84:2003;305-315
    • (2003) J. Neurochem. , vol.84 , pp. 305-315
    • Gonzalez-Polo, R.A.1    Soler, G.2    Alvarez, A.3    Fabregat, I.4    Fuentes, J.M.5
  • 7
    • 0030593914 scopus 로고    scopus 로고
    • Vitamins C and e prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax
    • Haendeler J., Zeiher A.M., Dimmeler S. Vitamins C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax. Eur. J. Pharmacol. 317:1996;407-411
    • (1996) Eur. J. Pharmacol. , vol.317 , pp. 407-411
    • Haendeler, J.1    Zeiher, A.M.2    Dimmeler, S.3
  • 8
  • 9
    • 0034012035 scopus 로고    scopus 로고
    • Amelioration of ethanol-induced neurotoxicity in the neonatal rat central nervous system by antioxidant therapy
    • Heaton M.B., Mitchell J.J., Paiva M. Amelioration of ethanol-induced neurotoxicity in the neonatal rat central nervous system by antioxidant therapy. Alcohol., Clin. Exp. Res. 24:2000;512-518
    • (2000) Alcohol., Clin. Exp. Res. , vol.24 , pp. 512-518
    • Heaton, M.B.1    Mitchell, J.J.2    Paiva, M.3
  • 10
    • 0036220143 scopus 로고    scopus 로고
    • Influence of ethanol on neonatal cerebellum of BDNF gene-deleted animals: Analyses of effects on Purkinje cells, apoptosis-related proteins, and endogenous antioxidants
    • Heaton M.B., Madorsky I., Paiva M., Mayer J. Influence of ethanol on neonatal cerebellum of BDNF gene-deleted animals: analyses of effects on Purkinje cells, apoptosis-related proteins, and endogenous antioxidants. J. Neurobiol. 51:2002;160-176
    • (2002) J. Neurobiol. , vol.51 , pp. 160-176
    • Heaton, M.B.1    Madorsky, I.2    Paiva, M.3    Mayer, J.4
  • 11
    • 1642459856 scopus 로고    scopus 로고
    • The role of neurotrophic factors, apoptosis-related proteins, and endogenous antioxidants in the differential temporal vulnerability of neonatal cerebellum to ethanol
    • Heaton M.B., Moore D.B., Paiva M., Madorsky I., Mayer J., Shaw G. The role of neurotrophic factors, apoptosis-related proteins, and endogenous antioxidants in the differential temporal vulnerability of neonatal cerebellum to ethanol. Alcohol., Clin. Exp. Res. 27:2003;657-669
    • (2003) Alcohol., Clin. Exp. Res. , vol.27 , pp. 657-669
    • Heaton, M.B.1    Moore, D.B.2    Paiva, M.3    Madorsky, I.4    Mayer, J.5    Shaw, G.6
  • 12
    • 0037448748 scopus 로고    scopus 로고
    • Effects of ethanol on neurotrophic factors, apoptosis-related proteins, endogenous antioxidants, and reactive oxygen species in neonatal striatum: Relationship to periods of vulnerability
    • Heaton M.B., Paiva M., Madorsky I., Mayer J., Moore D.B. Effects of ethanol on neurotrophic factors, apoptosis-related proteins, endogenous antioxidants, and reactive oxygen species in neonatal striatum: relationship to periods of vulnerability. Dev. Brain Res. 140:2003;237-252
    • (2003) Dev. Brain Res. , vol.140 , pp. 237-252
    • Heaton, M.B.1    Paiva, M.2    Madorsky, I.3    Mayer, J.4    Moore, D.B.5
  • 13
    • 0242384139 scopus 로고    scopus 로고
    • Ethanol effects on neonatal rat cortex: Comparative analyses of neurotrophic factors, apoptosis-related proteins, and oxidative processes during vulnerable and resistant periods
    • Heaton M.B., Paiva M., Madorsky I., Shaw G. Ethanol effects on neonatal rat cortex: comparative analyses of neurotrophic factors, apoptosis-related proteins, and oxidative processes during vulnerable and resistant periods. Dev. Brain Res. 145:2003;249-262
    • (2003) Dev. Brain Res. , vol.145 , pp. 249-262
    • Heaton, M.B.1    Paiva, M.2    Madorsky, I.3    Shaw, G.4
  • 15
  • 18
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan D.R., Miller F.D. Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10:2000;381-391
    • (2000) Curr. Opin. Neurobiol. , vol.10 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 19
    • 0032498829 scopus 로고    scopus 로고
    • Vitamin e protects against Alzheimer's amyloid peptide (25-35)-induced changes in neocortical synaptosomal membrane lipid structure and composition
    • Koppal T., Subramaniam R., Drake J., Prasad M.R., Dhillon H., Butterfield D.A. Vitamin E protects against Alzheimer's amyloid peptide (25-35)-induced changes in neocortical synaptosomal membrane lipid structure and composition. Brain Res. 786:1998;270-273
    • (1998) Brain Res. , vol.786 , pp. 270-273
    • Koppal, T.1    Subramaniam, R.2    Drake, J.3    Prasad, M.R.4    Dhillon, H.5    Butterfield, D.A.6
  • 20
    • 0028846081 scopus 로고
    • Ethanol-induced teratogenesis: Free radical damage as a possible mechanism
    • Kotch L., Chen S.-Y., Sulik K. Ethanol-induced teratogenesis: free radical damage as a possible mechanism. Teratology. 52:1995;128-136
    • (1995) Teratology , vol.52 , pp. 128-136
    • Kotch, L.1    Chen, S.-Y.2    Sulik, K.3
  • 21
    • 0022686460 scopus 로고
    • An automated colorimetric microassay for neuronotrophic factors
    • Manthorpe M., Fagnani R., Skaper S., Varon S. An automated colorimetric microassay for neuronotrophic factors. Dev. Brain Res. 25:1986;191-198
    • (1986) Dev. Brain Res. , vol.25 , pp. 191-198
    • Manthorpe, M.1    Fagnani, R.2    Skaper, S.3    Varon, S.4
  • 22
    • 0029150526 scopus 로고
    • Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons
    • Mattson M.P., Lovell M.A., Furukawa K., Markesbery W.R. Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. J. Neurochem. 65:1995;1740-1751
    • (1995) J. Neurochem. , vol.65 , pp. 1740-1751
    • Mattson, M.P.1    Lovell, M.A.2    Furukawa, K.3    Markesbery, W.R.4
  • 23
    • 0043245002 scopus 로고    scopus 로고
    • Embryonic exposure to exogenous alpha- and gamma-tocopherol partially attenuates ethanol-induced changes in brain morphology and brain membrane fatty acid composition
    • Miller R.R. Jr., Olson B.M., Rorick N., Wittingen A.L., Bullock M. Embryonic exposure to exogenous alpha- and gamma-tocopherol partially attenuates ethanol-induced changes in brain morphology and brain membrane fatty acid composition. Nutr. Neurosci. 6:2003;201-212
    • (2003) Nutr. Neurosci. , vol.6 , pp. 201-212
    • Miller Jr., R.R.1    Olson, B.M.2    Rorick, N.3    Wittingen, A.L.4    Bullock, M.5
  • 24
    • 0032006780 scopus 로고    scopus 로고
    • Optimal 96-well plate set-up to avoid ethanol volatility when assessing ethanol cytotoxicity
    • Mitchell J.J., Paiva M., Heaton M.B. Optimal 96-well plate set-up to avoid ethanol volatility when assessing ethanol cytotoxicity. Alcohol. 15:1998;137-139
    • (1998) Alcohol , vol.15 , pp. 137-139
    • Mitchell, J.J.1    Paiva, M.2    Heaton, M.B.3
  • 25
    • 0033605523 scopus 로고    scopus 로고
    • Vitamin e and β-carotene protect against ethanol combined with ischemia in an embryonic rat hippocampal culture model of fetal alcohol syndrome
    • Mitchell J.J., Paiva M., Heaton M.B. Vitamin E and β-carotene protect against ethanol combined with ischemia in an embryonic rat hippocampal culture model of fetal alcohol syndrome. Neurosci. Lett. 263:1999;189-192
    • (1999) Neurosci. Lett. , vol.263 , pp. 189-192
    • Mitchell, J.J.1    Paiva, M.2    Heaton, M.B.3
  • 26
    • 0035903061 scopus 로고    scopus 로고
    • Effects of prenatal exposure to ethanol on the expression of Bcl-2, bax and caspase 3 in the developing rat cerebral cortex and thalamus
    • Mooney S.M., Miller M.W. Effects of prenatal exposure to ethanol on the expression of Bcl-2, bax and caspase 3 in the developing rat cerebral cortex and thalamus. Brain Res. 911:2001;71-81
    • (2001) Brain Res. , vol.911 , pp. 71-81
    • Mooney, S.M.1    Miller, M.W.2
  • 27
    • 0032797345 scopus 로고    scopus 로고
    • Neonatal ethanol exposure alters Bcl-2 family mRNA levels in the rat cerebellar vermis
    • Moore D.B., Walker D.W., Heaton M.B. Neonatal ethanol exposure alters Bcl-2 family mRNA levels in the rat cerebellar vermis. Alcohol., Clin. Exp. Res. 23:1999;1251-1261
    • (1999) Alcohol., Clin. Exp. Res. , vol.23 , pp. 1251-1261
    • Moore, D.B.1    Walker, D.W.2    Heaton, M.B.3
  • 28
    • 0026446062 scopus 로고
    • Vitamin e attenuates the toxic effects of 6-hydroxydopamine on free radical scavenging systems in rat brain
    • Perumal A.S., Gopal V.B., Tordzro W.K., Cooper T.B., Cadet J.L. Vitamin E attenuates the toxic effects of 6-hydroxydopamine on free radical scavenging systems in rat brain. Brain Res. Bull. 29:1992;699-701
    • (1992) Brain Res. Bull. , vol.29 , pp. 699-701
    • Perumal, A.S.1    Gopal, V.B.2    Tordzro, W.K.3    Cooper, T.B.4    Cadet, J.L.5
  • 29
    • 0036179990 scopus 로고    scopus 로고
    • Mechanisms underlying the protective potential of alpha-tocopherol (vitamin E) against haloperidol-associated neurotoxicity
    • Post A., Rucker M., Ohl F., Uhr M., Holsboer F., Almeida O.F., Michaelidis T.M. Mechanisms underlying the protective potential of alpha-tocopherol (vitamin E) against haloperidol-associated neurotoxicity. Neuropsychopharmacology. 26:2002;397-407
    • (2002) Neuropsychopharmacology , vol.26 , pp. 397-407
    • Post, A.1    Rucker, M.2    Ohl, F.3    Uhr, M.4    Holsboer, F.5    Almeida, O.F.6    Michaelidis, T.M.7
  • 30
    • 0035159165 scopus 로고    scopus 로고
    • Vitamin E: Protective role of a Janus molecule
    • Ricciarelli R., Zingg J.M., Azzi A. Vitamin E: protective role of a Janus molecule. FASEB J. 15:2001;2314-2325
    • (2001) FASEB J. , vol.15 , pp. 2314-2325
    • Ricciarelli, R.1    Zingg, J.M.2    Azzi, A.3
  • 31
    • 2442604136 scopus 로고    scopus 로고
    • Pycnogenol® and vitamin e inhibit ethanol-induced apoptosis in rat cerebellar granule cells
    • (in press)
    • Siler-Marsiglio K.I., Shaw G., Heaton M.B. Pycnogenol® and vitamin E inhibit ethanol-induced apoptosis in rat cerebellar granule cells. J. Neurobiol. 2004;. (in press)
    • (2004) J. Neurobiol.
    • Siler-Marsiglio, K.I.1    Shaw, G.2    Heaton, M.B.3
  • 32
    • 0028791737 scopus 로고
    • Vitamin E: Beyond antioxidant function
    • Traber M.G., Packer L. Vitamin E: beyond antioxidant function. Am. J. Clin. Nutr. 62:1995;1501S-1509S
    • (1995) Am. J. Clin. Nutr. , vol.62
    • Traber, M.G.1    Packer, L.2
  • 33
    • 0035861890 scopus 로고    scopus 로고
    • Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis
    • Zhao M., Eaton J.W., Brunk U.T. Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis. FEBS Lett. 509:2001;405-412
    • (2001) FEBS Lett. , vol.509 , pp. 405-412
    • Zhao, M.1    Eaton, J.W.2    Brunk, U.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.