Ribosomal p70S6K basal activity increases upon induction of differentiation of myelomonocytic leukemic cell lines HL60, AML14 and MPD

Leukemia Research

Volumn 28, Issue 7, 2004, Pages 755-762

  Gomez Cambronero, Julian ^a   Frye, Tricia ^a   Baumann, Michael ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

Author keywords

acute myelocytic leukemia; AML; AML3D10; dHL 60; differentiated HL 60; eosinophilic AML; G CSF; GM CSF; granulocyte colony stimulating factor; granulocyte macrophage colony stimulating factor; HL 60; human promyelocytic leukemia; p70S6K; ribosomal p70 S6 kinase

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; PROTEIN SUBUNIT; RIBOSOMAL P70 S6 KINASE; RIBOSOME PROTEIN; SERINE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BLOOD; CELL DIFFERENTIATION; CELL MATURATION; CELL STIMULATION; CELL STRAIN HL 60; CONTROLLED STUDY; ENZYME ACTIVITY; GRANULOCYTE; HUMAN; HUMAN CELL; INCUBATION TIME; LEUKEMIA CELL; LEUKEMIA CELL LINE; MONOCYTIC LEUKEMIA; MYELOID LEUKEMIA; MYELOMONOCYTIC LEUKEMIA; NEUTROPHIL; PARAMETER; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

CELL DIFFERENTIATION; CELL LINE, TUMOR; ENZYME ACTIVATION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HL-60 CELLS; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; NEUTROPHILS; PHOSPHORYLATION; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA;

EID: 2442550853     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2003.11.012     Document Type: Article

References (39)

1. Jefferies H.B., Fumagalli S., Reinhard D., Pearson R.B., Thomas G. Rapamycin suppresses 5-TOP mRNA translation through inhibition of p70s6k. EMBO J. 16:1997;3693-3704
2. Kawasome H., Papst P., Webb S., Keller G.M., Johnson G.L., Gelfand E.W. Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity. Proc. Natl. Acad. Sci. USA. 95:1998;5033-5038
3. Nemenoff R.A., Price D.J., Mendelsohn M.J., Carter E.A., Avruch J. An S6 kinase activated during liver regeneration is related to the insulin-stimulated S6 kinase in H4 hepatoma cells. J. Biol. Chem. 263:1988;19455-19460
4. Proud C.G. p70 S6 kinase: an enigma with variations. Trends Biochem. Sci. 21:1996;181-185
5. Pullen N., Thomas G. The modular phosphorylation and activation of p70s6k. FEBS Lett. 410:1997;78-82
6. Scheid M.P., Charlton L., Pelech S.L., Duronio V. Role of p70 S6 kinase in cytokine-regulated hematopoietic cell survival. Biochem. Cell Biol. 74:1996;595-600
7. Grove J.R., Banerjee P., Balasubramanyam A., Coffer P.J., Price D.J., Avruch J., et al. Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini. Mol. Cell. Biol. 11:1991;5541-5550
8. Reinhard C., Fernandez A., Lamb N.J., Thomas G. Nuclear localization of p85s6k: functional requirement for entry into S phase. EMBO J. 13:1994;1557-1565
9. Gout I., Minami T., Hara K., Tsujishita Y., Filonenko V., Waterfield M.D., et al. Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase b containing a proline-rich region. J. Biol. Chem. 273:1998;30061-30064
10. Shima H., Pende M., Chen Y., Fumagalli S., Thomas G., Kozma S.C. Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase. EMBO J. 17:1998;6649-6659
11. Lee-Fruman K.K., Kuo C.J., Lippincott J., Terada N., Blenis J. Characterization of S6K2, a novel kinase homologous to S6K1. Oncogene. 18:1999;5108-5114
12. Price D.J., Grove J.R., Calvo V., Avruch J., Bierer B.E. Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science. 257:1992;973-977
13. Burnett P.E., Barrow R.K., Cohen N.A., Snyder S.H., Sabatini D.M. Raft1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc. Natl. Acad. Sci. U.S.A. 95:1998;1432-1437
14. Calvo V., Crews C.M., Vik T.A., Bierer B.E. Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. Proc. Natl. Acad. Sci. USA. 89:1992;7571-7575
15. Calvo V., Wood M., Gjerston C., Vik T., Bierer B.E. Activation of 70 kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation. Eur. J. Immunol. 24:1994;2664-2671
16. Reif K., Burgering B.M.T., Kantrell A. Phosphotidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase. J. Biol. Chem. 272:1997;14426-14433
17. Paul C.C., Tolbert M., Mahrer S., Singh A., Grace M.J., Baumann M.A. Cooperative effects of interleukine-3 (IL-3), IL05, and granulocyte-macrophage colony-stimulating factor: a new myeloid cell line inducible to eosinophils. Blood. 81:1993;1193-1199
18. Paul C.C., Aly E., Lehman J.A., Page S.M., Gomez-Cambronero J., Ackerman S.J., et al. Human cell line that differentiates to all myeloid lineages and expresses neutrophil secondary granule genes. Exp. Hematol. 28:2000;1373-1380
19. English D., Andersen B.R. Single-step separation of red blood cells. Granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque. J. Immunol. Meth. 5:1974;249-252
20. Newburger P.E., Chovaniec M.E., Greenberger J.S., Cohen H.J. Functional changes in a human leukemic cell line HL-60. A model for myeloid differentiation. J. Cell. Biol. 82:1979;315-322
21. Roberts P.J., Cross A.R., Jones O.T.G., Segal A.W. Development of cytochrome b and active oxidase system in association with maturation of a human promyelocytic (HL-60) cell line. J. Cell Biol. 95:1982;720-726
22. Collins S.J. The HL-60 cell line: proliferation. Blood. 70:1987;1233-1244
23. Paul C., Ackerman S.J., Mahrer S., Tolbert M., Dvorak A.M., Baumann M.A. Cytokine induction of granule protein synthesis in an eosinophil-inducible human myeloid cell line, AML14. J. Leukocyte Biol. 56:1994;74-79
24. Paul C.C., Mahrer S., Tolbert M., Elbert B.L., Wong I., Ackerman S.J., et al. Changing the differentiation program of hematopoietic cells: retinoic acid-induced shift of eosinophil-committed cells to neutrophils. Blood. 86:1995;3737-3744
25. Lehman J.A., Paul C.C., Baumann M.A., Gomez-Cambronero J. MAP kinase upregulation after hematopoietic differentiation: role of chemotaxis. Am. J. Physiol. Cell Physiol. 280:2001;183-191
26. rsk in GM-CSF-stimulated proliferative and mature hemopoietic cells. J. Biol. Chem. 271:1996;13088-13093
27. Gomez-Cambronero J. Rapamycin inhibits GM-CSF-induced neutrophil migration. FEBS Lett. 550:2003;94-100
28. 389-kinase. J. Biol. Chem. 278:2003;28130-28138
29. Gomez-Cambronero J., Veatch C. Emerging paradigms in granulocyte- macrophage colony-stimulating factor signaling. Life Sci. 59:1996;2099-2111
30. Conejo R., Valverde A.M., Benito M., Lorenzo M. Insulin produces myogenesis in C2C12 myoblasts by induction of NF-kappaB and downregulation of AP-1 activities. J. Cell Physiol. 186:2001;82-94
31. Coolican S.A., Samuel D.S., Ewton D.Z., McWade F.J., Florini J.R. The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. J. Biol. Chem. 272:1997;6653-6662
32. Cuenda A., Cohen P. Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesis. J. Biol. Chem. 274:1999;4341-4346
33. Erbay E., Chen J. The mammalian target of rapamycin regulates C2C12 myogenesis via a kinase-independent mechanism. J. Biol. Chem. 276:2001;36079-36082
34. Kanayasu-Toyoda T., Yamaguchi T., Oshizawa T., Kogi M., Uchida E., Hayakawa T. Role of the p70 S6 kinase cascade in neutrophilic differentiation and proliferation of HL-60 cells-a study of transferrin receptor-positive and negative cells obtained from dimethyl sulfoxide- or retinoic acid-treated HL-60 cells. Arch. Biochem. Biophys. 405:2002;21-31
35. Kanayasu-Toyoda T., Yamaguchi T., Uchida E., Hayakawa T. Commitment of neutrophilic differentiation and proliferation of HL-60 cells coincides with expression of transferrin receptor. Effect of granulocyte colony stimulating factor on differentiation and proliferation. J. Biol. Chem. 274:1999;25471-25480
36. Yamaguchi T., Mukasa T., Uchida E., Kanayasu-Toyoda T., Hayakawa T. The role of STAT3 in granulocyte colony-stimulating factor-induced enhancement of neutrophilic differentiation of Me2SO-treated HL-60 cells. GM-CSF inhibits the nuclear translocation of tyrosine-phosphorylated STAT3. J. Biol. Chem. 274:1999;15575-15581
37. Valentinis B., Navarro M., Zanocco-Marani T., Edmond P., McCormick J., Morrione A., et al. Insulin receptor substrate-1, p70S6K and cell size in transformation and differentiation of hemopoietic cells. J. Biol. Chem. 275:2000;25451-25459
38. Birkenkamp K.U., Essenlink M.T., Kruijer W., Vellenga E. An inhibitor of PI3-K differentially affects proliferation and IL-6 protein secretion in normal and leukemic myeloid cells depending on the stage of differentiation. Exp. Hematol. 28:2000;1239-1249
39. Kanayasu-Toyoda T., Yamaguchi T., Oshizawa T., Uchida E., Hayakawa T. The role of c-Myc on granulocyte colony-stimulating factor-dependent neutrophilic proliferation and differentiation of HL-60 cells. Biochem. Pharmacol. 66:2003;133-140