메뉴 건너뛰기




Volumn 24, Issue 2 A, 2004, Pages 433-440

Two-deoxyglucose as an Anti-metabolite in Human Carcinoma Cell Line RPMI-2650 and Drug-resistant Variants

Author keywords

2 DG uptake; Altered glucose metabolism; Drug resistance

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIMETABOLITE; DEOXYGLUCOSE; GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCOSE TRANSPORTER; GLUTAMINE; HEXOKINASE; IODOACETIC ACID; MELPHALAN; PACLITAXEL DERIVATIVE; PENTOSE PHOSPHATE;

EID: 2442509090     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (14)

References (39)
  • 1
    • 0029035877 scopus 로고
    • Modification of tumour glucose metabolism for therapeutic benefit
    • Hamilton E, Fennel M and Stafford D: Modification of tumour glucose metabolism for therapeutic benefit. Acta Oncologica 34: 429-433, 1995.
    • (1995) Acta Oncologica , vol.34 , pp. 429-433
    • Hamilton, E.1    Fennel, M.2    Stafford, D.3
  • 2
    • 0032190467 scopus 로고    scopus 로고
    • Enhancement of doxorubicin content by the antitumor drug lonidamine in resistant Ehrlich ascites tumor cells through modulation of energy metabolism
    • Floridi A, Bruno T, Miccadei S, Fanciulli M, Federico A and Paggi MG: Enhancement of doxorubicin content by the antitumor drug lonidamine in resistant Ehrlich ascites tumor cells through modulation of energy metabolism. Biochem Pharm 56: 841-849, 1998.
    • (1998) Biochem Pharm , vol.56 , pp. 841-849
    • Floridi, A.1    Bruno, T.2    Miccadei, S.3    Fanciulli, M.4    Federico, A.5    Paggi, M.G.6
  • 3
    • 0029444685 scopus 로고
    • Antisense GLUT1 RNA suppresses the transformating phenotypes of NIH 3T3 cells transformed by N-Ras
    • Choi Jw, Yoon DJ, Lee Hw, Han Dp and Ahn Yh: Antisense GLUT1 RNA suppresses the transformating phenotypes of NIH 3T3 cells transformed by N-Ras. Yonsei Med J 36: 480-486, 1995.
    • (1995) Yonsei Med J , vol.36 , pp. 480-486
    • Choi, Jw.1    Yoon, D.J.2    Lee, Hw.3    Han, Dp.4    Ahn, Yh.5
  • 5
    • 0031693121 scopus 로고    scopus 로고
    • The importance of glucose transport activity as the rate limiting step of 2-deoxyglucose uptake in tumor cells in vitro
    • Waki A, Kato H, Yano R, Sadato N, Yokoyama A, Ishii Y, Yonekura Y and Fujibashi Y: The importance of glucose transport activity as the rate limiting step of 2-deoxyglucose uptake in tumor cells in vitro. Nuc Med Biol 25: 593-597, 1998.
    • (1998) Nuc Med Biol , vol.25 , pp. 593-597
    • Waki, A.1    Kato, H.2    Yano, R.3    Sadato, N.4    Yokoyama, A.5    Ishii, Y.6    Yonekura, Y.7    Fujibashi, Y.8
  • 6
    • 0033568454 scopus 로고    scopus 로고
    • Glut-1 and hexokinase expression: Relationship with 2-fluoro-2-deoxy-D-glucose uptake in A431 and T47D cells in culture
    • Aloj L, Caraco C, Jagoda E, Eckelman WC and Neumann RD: Glut-1 and hexokinase expression: Relationship with 2-fluoro-2-deoxy-D-glucose uptake in A431 and T47D cells in culture. Cancer Res 59: 4709-4714, 1999.
    • (1999) Cancer Res , vol.59 , pp. 4709-4714
    • Aloj, L.1    Caraco, C.2    Jagoda, E.3    Eckelman, W.C.4    Neumann, R.D.5
  • 8
    • 0029065870 scopus 로고
    • PET studies in patients with locally advanced and/or metastatic breast cancer - A method for early therapy evaluation
    • Jansson T, Westlin JE, Ahlstrom H, Lilja A, Langstrom B and Bergh J: PET studies in patients with locally advanced and/or metastatic breast cancer - a method for early therapy evaluation. J Clin Oncology 13: 1470-1477, 1995.
    • (1995) J Clin Oncology , vol.13 , pp. 1470-1477
    • Jansson, T.1    Westlin, J.E.2    Ahlstrom, H.3    Lilja, A.4    Langstrom, B.5    Bergh, J.6
  • 10
    • 0032894299 scopus 로고    scopus 로고
    • Positron emisson tomography for evaluating para-aortic nodal metastasis in locally advanced cervical cancer before surgical staging: A surgicopathologic study
    • Rose PG, Adler LP, Rodriguez M, Faulhaber PF, Abdul-Karim FW and Miraldi F: Positron emisson tomography for evaluating para-aortic nodal metastasis in locally advanced cervical cancer before surgical staging: A surgicopathologic study. J Clin Oncology 17: 41-45, 1999.
    • (1999) J Clin Oncology , vol.17 , pp. 41-45
    • Rose, P.G.1    Adler, L.P.2    Rodriguez, M.3    Faulhaber, P.F.4    Abdul-Karim, F.W.5    Miraldi, F.6
  • 11
    • 0031796023 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose preferentially kills multidrug-resistant human KB carcinoma cell lines by apoptosis
    • Bell SE, Quinn DM, Kellett GL and Warr JR: 2-deoxy-D-glucose preferentially kills multidrug-resistant human KB carcinoma cell lines by apoptosis. B J Cancer 78(11): 1464-1470, 1998.
    • (1998) B J Cancer , vol.78 , Issue.11 , pp. 1464-1470
    • Bell, S.E.1    Quinn, D.M.2    Kellett, G.L.3    Warr, J.R.4
  • 12
    • 0031959734 scopus 로고    scopus 로고
    • 2-Deoxyglucose inhibits chemotherapeutic drug-induced apoptosis in human monocytic leukaemia U937 cells with inhibition of c-Jun N-terminal kinase 1 stress-activated protein kinase activation
    • Haga N, Naito M, Seimiya H, Tomida A, Dong J and Tsuruo T: 2-Deoxyglucose inhibits chemotherapeutic drug-induced apoptosis in human monocytic leukaemia U937 cells with inhibition of c-Jun N-terminal kinase 1 stress-activated protein kinase activation. Int J Cancer 76 (1): 86-90, 1998.
    • (1998) Int J Cancer , vol.76 , Issue.1 , pp. 86-90
    • Haga, N.1    Naito, M.2    Seimiya, H.3    Tomida, A.4    Dong, J.5    Tsuruo, T.6
  • 14
    • 0015853344 scopus 로고
    • Mutation of the head of bacteriophage T4
    • Laemmli E and Favre M: Mutation of the head of bacteriophage T4. J Mol Biol 80: 575-579, 1973.
    • (1973) J Mol Biol , vol.80 , pp. 575-579
    • Laemmli, E.1    Favre, M.2
  • 15
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedures and some applications
    • Towbin H, Staehelin T and Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedures and some applications. Proc Natl Acad Sci USA 76: 4350-4354, 1979.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 17
    • 0020435680 scopus 로고
    • Glucose-6-phosphate dehydrogenase from mouse
    • Lee Cy: Glucose-6-phosphate dehydrogenase from mouse. Methods Enzymol 89: 252-257, 1982.
    • (1982) Methods Enzymol , vol.89 , pp. 252-257
    • Lee, Cy.1
  • 18
    • 0025774712 scopus 로고
    • Acid phosphatase endpoint for in vitro toxicity testing
    • Martin A and Clynes M: Acid phosphatase endpoint for in vitro toxicity testing. In Vitro Dev Biol 27A: 183-184, 1991.
    • (1991) In Vitro Dev Biol , vol.27 A , pp. 183-184
    • Martin, A.1    Clynes, M.2
  • 19
    • 0034742666 scopus 로고    scopus 로고
    • Positron emission tomography with 2-18F-fluoro-2-deoxy-D-glucose in oncology. Part IIIb: Therapy response monitoring in colorectal and lung tumors, head and neck cancer, hepatocellular carcinoma and sarcoma
    • Stokkel MP, Draisma A and Pauwels EK: Positron emission tomography with 2-18F-fluoro-2-deoxy-D-glucose in oncology. Part IIIb: Therapy response monitoring in colorectal and lung tumors, head and neck cancer, hepatocellular carcinoma and sarcoma. J Cancer Res Clin Oncol 127: 278-285, 2001.
    • (2001) J Cancer Res Clin Oncol , vol.127 , pp. 278-285
    • Stokkel, M.P.1    Draisma, A.2    Pauwels, E.K.3
  • 20
    • 0029864659 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose toxicity and transport in human multidrug-resistant KB carcinoma cell lines
    • Bently J, Bell SE, Quinn DM, Kellett GL and Warr JR: 2-deoxy-D-glucose toxicity and transport in human multidrug-resistant KB carcinoma cell lines. Oncology Res 8(2): 77-84, 1996.
    • (1996) Oncology Res , vol.8 , Issue.2 , pp. 77-84
    • Bently, J.1    Bell, S.E.2    Quinn, D.M.3    Kellett, G.L.4    Warr, J.R.5
  • 21
    • 0033020904 scopus 로고    scopus 로고
    • Optimizing radiation therapy of brain tumours by combination of 5-bromo-2-deoxy-uridine and 2-deoxy-D-glucose
    • Kalia VK: Optimizing radiation therapy of brain tumours by combination of 5-bromo-2-deoxy-uridine and 2-deoxy-D-glucose. Indian J Med Res 109: 182-187, 1999.
    • (1999) Indian J Med Res , vol.109 , pp. 182-187
    • Kalia, V.K.1
  • 22
    • 0033797094 scopus 로고    scopus 로고
    • Positron-emission tomography with F-18 fluorodeoxyglucose Part 1. Biochemical uptake mechanisms and its implications for clinical studies
    • Pauwels EKJ, Sturm EJC, Bombardieri E, Cleton FJ and Stokkel MPM: Positron-emission tomography with F-18 fluorodeoxyglucose Part 1. Biochemical uptake mechanisms and its implications for clinical studies. J Can Res Clin Oncol 126(10): 549-559, 2000.
    • (2000) J Can Res Clin Oncol , vol.126 , Issue.10 , pp. 549-559
    • Pauwels, E.K.J.1    Sturm, E.J.C.2    Bombardieri, E.3    Cleton, F.J.4    Stokkel, M.P.M.5
  • 24
    • 0023930530 scopus 로고
    • Glucose metabolism in drug-sensitive and drug-resistant human breast cancer cells monitored by magnetic resonance spectroscopy
    • Lyon R, Cohen JS, Faustino PJ, Megnin F and Myers CE: Glucose metabolism in drug-sensitive and drug-resistant human breast cancer cells monitored by magnetic resonance spectroscopy. Cancer Res 48: 870-877, 1988.
    • (1988) Cancer Res , vol.48 , pp. 870-877
    • Lyon, R.1    Cohen, J.S.2    Faustino, P.J.3    Megnin, F.4    Myers, C.E.5
  • 25
    • 0027892859 scopus 로고
    • Glucose metabolism in adriamycin-sensitive and -resistant LoVo human colon carcinoma cells
    • Faniculli M, Bruno T, Castiglione S, Del Carlo C, Paggi M and Floridi A: Glucose metabolism in adriamycin-sensitive and - resistant LoVo human colon carcinoma cells. Oncology Res 5: 357-362, 1993.
    • (1993) Oncology Res , vol.5 , pp. 357-362
    • Faniculli, M.1    Bruno, T.2    Castiglione, S.3    Del Carlo, C.4    Paggi, M.5    Floridi, A.6
  • 26
    • 0030009424 scopus 로고    scopus 로고
    • Energy metabolism of adriamycin-sensitive and -resistant Ehrlich ascites tumor cells
    • Miccadi S, Fanciulli M, Bruno T, Paggi MG and Floridi A: Energy metabolism of adriamycin-sensitive and -resistant Ehrlich ascites tumor cells. Oncology Res 8: 27-35, 1996.
    • (1996) Oncology Res , vol.8 , pp. 27-35
    • Miccadi, S.1    Fanciulli, M.2    Bruno, T.3    Paggi, M.G.4    Floridi, A.5
  • 27
    • 0035038457 scopus 로고    scopus 로고
    • Selection with mephalan or taxol yields variants with different patterns of multidrug resistance, integrin expression and in vitro invasiveness
    • Liang Y, Meleady P, Cleary I, McDonnell S, Connolly L and Clynes M: Selection with mephalan or taxol yields variants with different patterns of multidrug resistance, integrin expression and in vitro invasiveness. E J Cancer 37: 1041-1052, 2001.
    • (2001) E J Cancer , vol.37 , pp. 1041-1052
    • Liang, Y.1    Meleady, P.2    Cleary, I.3    McDonnell, S.4    Connolly, L.5    Clynes, M.6
  • 29
    • 0035043896 scopus 로고    scopus 로고
    • In vitro and in vivo tracer characteristics of an established multidrug-resistant human colon cancer cell line
    • Lorke DE, Kruger M, Buchert R, Bohuslavizki KH, Clausen M and Schumacher U: In vitro and in vivo tracer characteristics of an established multidrug-resistant human colon cancer cell line. J Nuc Med 42(4): 646-654, 2001.
    • (2001) J Nuc Med , vol.42 , Issue.4 , pp. 646-654
    • Lorke, D.E.1    Kruger, M.2    Buchert, R.3    Bohuslavizki, K.H.4    Clausen, M.5    Schumacher, U.6
  • 30
    • 0028152377 scopus 로고
    • Facilitative glucose transporters
    • Mueckler M: Facilitative glucose transporters. Eur J Biochem 219: 713-725, 1994.
    • (1994) Eur J Biochem , vol.219 , pp. 713-725
    • Mueckler, M.1
  • 31
    • 0033079597 scopus 로고    scopus 로고
    • Oncogenic alterations of metabolism
    • Dang CV and Semenza GL: Oncogenic alterations of metabolism. TIBS 24: 68-72, 1999.
    • (1999) TIBS , vol.24 , pp. 68-72
    • Dang, C.V.1    Semenza, G.L.2
  • 32
    • 0030023026 scopus 로고    scopus 로고
    • Wide expression of the human erythrocyte glucose transporter Glut 1 in human cancers
    • Younes M, Lechago LV, Somoano JR, Mosharaf M and Lechago J: Wide expression of the human erythrocyte glucose transporter Glut 1 in human cancers. Cancer Res 56: 1164-1167, 1996.
    • (1996) Cancer Res , vol.56 , pp. 1164-1167
    • Younes, M.1    Lechago, L.V.2    Somoano, J.R.3    Mosharaf, M.4    Lechago, J.5
  • 34
    • 0344549438 scopus 로고    scopus 로고
    • Glucose uptake in malignant tumors of the head and neck
    • Reisser C, Eichtlorn K and Herold-Mende C: Glucose uptake in malignant tumors of the head and neck. HNO 47: 712-717, 1999.
    • (1999) HNO , vol.47 , pp. 712-717
    • Reisser, C.1    Eichtlorn, K.2    Herold-Mende, C.3
  • 35
    • 0031823577 scopus 로고    scopus 로고
    • Expression of two type II-like tumor hexokinasee RNA transcripts in cancer cell lines
    • Sebastian S and Kenkare UW: Expression of two type II-like tumor hexokinasee RNA transcripts in cancer cell lines. Tumor Biology 19: 253-260, 1998.
    • (1998) Tumor Biology , vol.19 , pp. 253-260
    • Sebastian, S.1    Kenkare, U.W.2
  • 36
    • 0024237766 scopus 로고
    • Pedersen: Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP
    • Arora K and Pedersen: Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP. J Biol Chem 263: 17422-17428, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 17422-17428
    • Arora, K.1
  • 37
    • 0026073188 scopus 로고
    • Determination of 2-Fluoro-2-deoxyglucose uptake and ATP level for evaluating drug effects in neoplastic-cells
    • Minn H, Kangas L, Knuutila V, Paul R and Sipila H: Determination of 2-Fluoro-2-deoxyglucose uptake and ATP level for evaluating drug effects in neoplastic-cells. Res Exp Med 191: 27-35, 1991.
    • (1991) Res Exp Med , vol.191 , pp. 27-35
    • Minn, H.1    Kangas, L.2    Knuutila, V.3    Paul, R.4    Sipila, H.5
  • 38
    • 0027189916 scopus 로고
    • Glycolytic, glutaminolytic and pentose-phosphate pathways in promyelocytic HL60 and DMSO-differentiated HL60 cells
    • Ahmed N, Williams JF and Weidemann MJ: Glycolytic, glutaminolytic and pentose-phosphate pathways in promyelocytic HL60 and DMSO-differentiated HL60 cells. Biochem Mol Biol Intl 1055-1067, 1993.
    • (1993) Biochem Mol Biol Intl , vol.60 , pp. 1055-1067
    • Ahmed, N.1    Williams, J.F.2    Weidemann, M.J.3
  • 39
    • 0032126508 scopus 로고
    • Proliferation is associated with 2-deoxy-D-[1-H-3]glucose uptake by T47D breast tumour and SW 480 and SW620 colonic tumour cells
    • Smith TAD, Titley JC and McCready VR: Proliferation is associated with 2-deoxy-D-[1-H-3]glucose uptake by T47D breast tumour and SW 480 and SW620 colonic tumour cells. Nuc Med and Biol 25(5): 481-485, 1993.
    • (1993) Nuc Med and Biol , vol.25 , Issue.5 , pp. 481-485
    • Smith, T.A.D.1    Titley, J.C.2    McCready, V.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.