Optimal fermentation conditions for enhanced glutathione production by Saccharomyces cerevisiae FF-8

Journal of Microbiology

Volumn 42, Issue 1, 2004, Pages 51-55

  Cha, Jae Young ^a   Park, Jin Chul ^a   Jeon, Beong Sam ^b   Lee, Young Choon ^a   Cho, Young Su ^a  

^a Dong A University   (South Korea)

^b Gyeongsang National University   (South Korea)

Author keywords

Glucose; Glutathione; L cysteine; Saccharomyces cerevisiae; Yeast

Indexed keywords

GLUTATHIONE;

ARTICLE; CARBON SOURCE; CULTURE MEDIUM; ENZYME SYNTHESIS; FERMENTATION OPTIMIZATION; FUNGAL STRAIN; FUNGUS CULTURE; FUNGUS GROWTH; NONHUMAN; SACCHAROMYCES CEREVISIAE;

BIOREACTORS; BIOTECHNOLOGY; CULTURE MEDIA; CYSTEINE; FERMENTATION; GLUCOSE; GLUTATHIONE; PHOSPHATES; POTASSIUM COMPOUNDS; SACCHAROMYCES CEREVISIAE; TIME FACTORS; YEASTS;

FUNGI; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 2442486776     PISSN: 12258873     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Alfafara, C.G., A. Kanda, T. Shioi, H. Shimizu, S. Shioya, and K. Suga. 1992. Effect of amino acids on glutathione production by Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 36, 538-540.
2. Alfafara, C.G., K. Miura, H. Shimizu, S. Shioya, and K. Suga. 1992. Cysteine addition strategy for maximum glutathione production in fed-batch culture of Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 37, 141-146.
3. Berhane, K., M. Widersten, A. Engstrom, J.W. Kozarich, and B. Mannervik. 1994. Detoxication of base propenals and other, -unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferase. Proc. Natl. Acad, Sci. USA, 91, 1480-1484.
4. Cohn, V.H. and J. Lyle. 1966. A fluorometric assay for glutathione. Anal. Biochem. 14, 434-440.
5. Goto, S., K. Yoshida, T. Morikawa, Y. Urata, K. Suzuki, and T. Kondo. 1995. Augmentation of transport for cisplatin-glutathione adduct in cisplatin-resistant cancer cells. Cancer Res. 55, 4297-4301.
6. Kim, D.S., J.H. Yu, S.S. Yoon, and W.C. Shin. 1993. Isolation, identification and culture condition of microorganism producing glutathione. Kor. J. Appl. Microbiol. Biotechnol. 21, 435-439.
7. Li, Y., J. Chen, N. Zhou, W. Fu, W. Ruan, and S. Lun. 1998a. Effects of amino acids and yeast extract on glutathione production. Chin. J. Pharm 29, 537-542.
8. Li, Y., J. Chen, N. Zhou, W. Fu, W. Ruan, and S. Lun. 1998b. The effect of environmental conditions and glucose feeding strategy on lutathione(GSH) production. Chin. J. Biotechnol. 14, 85-91.
9. Li, Y., J. Chen, Y Mao, S. Lun, and Y.M. Koo. 1999. Fermentation conditions for production of glutathione by recombinant Escherichia coli. Wei Sheng Bao Xue Bao. 39, 355-361.
10. Meister, A. and S.S. Tate. 1976. Glutathione and related -glutamyl compounds: biosynthesis and utilization. Annu. Rev. Biochem. 45, 559-604.
11. Park, J.C., M. Ok, J.Y. Cha, and Y.S. Cho. 2003. Isolation and identification of the high-glutathione producing Saccharomyces cerevisiae FF-8 from Korean Traditional Rice Wine and optimal producing conditions. J. Korean Soc. Agric. Chem. Biotechnol. 46, 348-352.
12. Perego, P., J.V. Weghe, D.W. Ow, and D.W. Howell. 1997. Role of determinants of cadmium sensitivity in the tolerance of Schizosaccharomyces pombe to cisplatin. Mol. Pharmacol. 51, 12-18.
13. Sakato, K. and H. Tanaka. 1992. Advanced control of glutathione fermentation process. Biotechnol. Bioeng. 40, 904-912.
14. Shimiz, H., K. Araki, and S. Shioya. 1991. Optimal production of glutathione by controlling the specific growth rate of yeast in fed-batch culture. Biotechnol. Bioeng. 38, 196-205.
15. Shin, W.C., D.S. Kim, J.H. Yu, and J.H. Yu. 1993. Isolation, identification and culture condition of microorganism producing glutathione. Kor. J. Appl. Microbiol. Biotechnol. 21, 1-5.
16. Sollod, C.C., A.E. Jenns, and M.E. Daub. 1992. Cell surface redox potential as a mechanism of defense against photosensitizers in fungi. Appl. Environ. Microbiol. 58, 444-449.
17. Wei, G., Y. Li, and J. Chen. 2003a. Effect of surfactants on extracellular accumulation of glutathione by Saccharomyces cerevisiae. Process Biochem. 38, 1133-1138.
18. Wei, G., Y. Li, and J. Chen. 2003b. Application of a two-stage temperature control strategy for enhanced glutathione production in the batch fermentation by Candida utilis. Biotechnol. Lett. 25, 887-890.