The Mouse Formin, FRLα, Slows Actin Filament Barbed End Elongation, Competes with Capping Protein, Accelerates Polymerization from Monomers, and Severs Filaments

Journal of Biological Chemistry

Volumn 279, Issue 19, 2004, Pages 20076-20087

  Harris, Elizabeth S ^a   Li, Fang ^a   Higgs, Henry N ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DIMERS; ENZYME INHIBITION; MONOMERS; POLYMERIZATION; PROTEINS; TISSUE;

ACTIN FILAMENTS; EUKARYOTIC CELLS; FORMINS;

BIOCHEMISTRY;

ACTIN; CAPPING PROTEIN; CELL PROTEIN; DIMER; MONOMER; PROFILIN; PROTEIN; PROTEIN FORMIN; PROTEIN FRLALPHA; PROTEIN MDIA1; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; CARRIER PROTEIN; DNA; FMNL1 PROTEIN, MOUSE; SIGNAL PEPTIDE;

ACTIN FILAMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EUKARYOTE; HEMATOPOIETIC CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; ANIMAL; BINDING COMPETITION; BIOLOGICAL MODEL; CHEMISTRY; DIMERIZATION; DOSE RESPONSE; ESCHERICHIA COLI; GEL CHROMATOGRAPHY; KINETICS; METABOLISM; MUSCLE; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN TERTIARY STRUCTURE; SPECTROFLUOROMETRY; TIME; TUMOR CELL LINE; WESTERN BLOTTING;

EUKARYOTA; MAMMALIA;

ACTINS; ANIMALS; BINDING, COMPETITIVE; BLOTTING, WESTERN; CARRIER PROTEINS; CELL LINE, TUMOR; CHROMATOGRAPHY, GEL; DIMERIZATION; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; MICE; MODELS, BIOLOGICAL; MUSCLES; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, FLUORESCENCE; TIME FACTORS;

EID: 2442473140     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312718200     Document Type: Article

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