The functional significance of cell clusters in the notochordal nucleus pulposus: Survival and signaling in the canine intervertebral disc

Spine

Volumn 29, Issue 10, 2004, Pages 1099-1104

  Hunter, Christopher J ^a   Matyas, John R ^a   Duncan, Neil A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Cell signaling; Cell survival; Intervertebral disc; Notochord; Nucleus pulposus

Indexed keywords

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLEACHING; CARTILAGE CELL; CELL AGGREGATION; CELL COMMUNICATION; CELL DISRUPTION; CELL FUNCTION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOG; ENZYMATIC DEGRADATION; FLUORESCENCE; GAP JUNCTION; IN VITRO STUDY; INTERVERTEBRAL DISK; NERVE DEGENERATION; NONHUMAN; NOTOCHORD; NUCLEUS PULPOSUS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; CELL AGGREGATION; CELL COMMUNICATION; CELL SURVIVAL; DOGS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GAP JUNCTIONS; INCLUSION BODIES; INTERVERTEBRAL DISK; NOTOCHORD;

EID: 2442446008     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-200405150-00010     Document Type: Article

References (41)

1. Walmsley R. The development and growth of the intervertebral disc. Edinburgh Med J. 1953;60:341-363.
2. Bell GR. Anatomy of the lumbar spine: developmental to normal adult anatomy. In: Wiesel SW, Weinstein JN, Herkowitz HN, et al, eds. The Lumbar Spine, 2nd ed. Philadelphia: Saunders, 1996:43-52.
3. Horwitz T. The Human Notochord: A Study of Its Development and Regression, Variations, and Pathologic Derivative, Chordoma. Indianapolis: Horwitz, 1977.
4. Zhu Y, McAlinden A, Sandell LJ. Type IIA procollagen in development of the human intervertebral disc: regulated expression of the NH(2)-propeptide by enzymic processing reveals a unique developmental pathway. Dev Dyn. 2001;220:350-362.
5. Gotz W, Kasper M, Miosge N, et al. Detection and distribution of the carbohydrate binding protein galectin-3 in human notochord, intervertebral disc and chordoma. Differentiation. 1997;62:149-157.
6. Stosiek P, Kasper M, Karsten U. Expression of cytokeratin and vimentin in nucleus pulposus cells. Differentiation. 1988;39:78-81.
7. Trout JJ, Buckwalter JA, Moore KC. Ultrastructure of the human intervertebral disc: II. Cells of the nucleus pulposus. Anat Rec. 1982;204:307-314.
8. Johnstone B, Bayliss MT. The large proteoglycans of the human intervertebral disc: changes in their biosynthesis and structure with age, topography, and pathology. Spine. 1995;20:674-684.
9. Roberts S, Menage J, Duance V, et al. Volvo Award in basic sciences. Collagen types around the cells of the intervertebral disc and cartilage end plate: an immunolocalization study. Spine. 1991;16:1030-1038.
10. Butler WF. Comparative anatomy and development of the mammalian disc. In: Gosh P, ed. The Biology of the Intervertebral Disc. Boca Raton: CRC Press, 1989:84-108.
11. Urban JP. Disc biochemistry in relation to function. In: Wiesel SW, Weinstein JN, Herkowitz HN, et al, eds. The Lumbar Spine, 2nd ed. Philadelphia: Saunders, 1996:271-281.
12. DePalma AF, Rothman RH. The Intervertebral Disc, 1st ed. Philadelphia: Saunders, 1970.
13. Holm SH. Nutritional and pathophysiologic aspects of the lumbar intervertebral disc. In: Wiesel SW, Weinstein JN, Herkowitz HN, et al, eds. The Lumbar Spine, 2nd ed. Philadelphia: Saunders, 1996:285-310.
14. Urban JP, Roberts S. Development and degeneration of the intervertebral discs. Mol Med Today. 1995;1:329-335.
15. Masuda K, Miyabayashi T, Meachum SH, et al. Proliferation of canine intervertebral disk chondrocytes in three-dimensional alginate microsphere culture. J Vet Med Sci. 2002;64:79-82.
16. Maldonado BA, Oegema TRJ. Initial characterization of the metabolism of intervertebral disc cells encapsulated in microspheres. J Orthop Res. 1992;10:677-690.
17. Baer AE, Wang JY, Kraus VB, et al. Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures. J Orthop Res. 2001;19:2-10.
18. Aguiar DJ, Johnson SL, Oegema TR. Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis. Exp Cell Res. 1999;246:129-137.
19. Hunter CJ, Matyas JR, Duncan NA. The three-dimensional architecture of the notochordal nucleus pulposus: novel observations on cell structures in the canine intervertebral disc. J Anat. 2003;202:279-292.
20. Hansen HJ. A pathologic-anatomical study on disc degeneration in dog. Acta Orthop Scand Suppl. 1952;11:1-17.
21. Bray JP, Burbidge HM. The canine intervertebral disk: II. Degenerative changes-nonchondrodystrophoid versus chondrodystrophoid disks. J Am Anim Hosp Assoc. 1998;34:135-144.
22. Thompson JP, Pearce RH, Schechter MT, et al. Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc. Spine. 1990;15:411-415.
23. Grogan SP, Aklin B, Frenz M, et al. In vitro model for the study of necrosis and apoptosis in native cartilage. J Pathol. 2002;198:5-13.
24. Wade MH, Trosko JE, Schindler M. A fluorescence photobleaching assay of gap junction-mediated communication between human cells. Science. 1986;232:525-528.
25. Dowling-Warriner CV, Trosko JE. Induction of gap junctional intercellular communication, connexin43 expression, and subsequent differentiation in human fetal neuronal cells by stimulation of the cyclic AMP pathway. Neuroscience. 2000;95:859-868.
26. Erwin WM, Paiwand F, Inman R. Is the notochord key to intervertebral disc homeostasis? 49th Annual Meeting of the Orthopaedic Research Society. New Orleans, LA, 2003;89.
27. DiPaola CP, Farmer JC, Manova K, et al. Molecular signaling in intervertebral disc development. 49th Annual Meeting of the Orthopaedic Research Society. New Orleans, LA, 2003:1134.
28. Essner JJ, Laing JG, Beyer EC, et al. Expression of zebrafish connexin43.4 in the notochord and tail bud of wild-type and mutant no tail embryos. Dev Biol. 1996;177:449-462.
29. Lehtonen E, Stefanovic V, Saraga-Babic M. Changes in the expression of intermediate filaments and desmoplakins during development of human notochord. Differentiation. 1995;59:43-49.
30. Schmitz RJ. Ultrastructure and function of cellular components of the intercentral joint in the percoid vertebral column. J Morphol. 1995;226:1-24.
31. Yellowley CE, Li Z, Zhou Z, et al. Functional gap junctions between osteocytic and osteoblastic cells. J Bone Miner Res. 2000;15:209-217.
32. Coelho CN, Kosher RA. Gap junctional communication during limb cartilage differentiation. Dev Biol. 1991;144:47-53.
33. Donahue HJ, Guilak F, Vander Molen MA, et al. Chondrocytes isolated from mature articular cartilage retain the capacity to form functional gap junctions. J Bone Miner Res. 1995;10:1359-1364.
34. Alberts B, Bray D, Lewis J, et al. Molecular Biology of the Cell, 3rd ed. New York: Garland, 1995.
35. Donahue HJ. Gap junctions and biophysical regulation of bone cell differentiation. Bone. 2000;26:417-422.
36. Frisch SM, Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol. 1994;124:619-626.
37. Bates RC, Buret A, van Helden DF, et al. Apoptosis induced by inhibition of intercellular contact. J Cell Biol. 1994;125:403-415.
38. Leeson TS, Leeson CR. Observations on the histochemistry and fine structure of the notochord in rabbit embryos. J Anat. 1958;92:278-285.
39. Trout JJ, Buckwalter JA, Moore KC, et al. Ultrastructure of the human intervertebral disc: I. Changes in notochordal cells with age. Tissue Cell. 1982;14:359-369.
40. Sisto DL, Corvetti G, Panattoni GL. Notochord degeneration in chick embryo: a particular case of developmental cell death? Eur J Morphol. 1995;33:403-414.
41. Sisto DL, Corvetti G, Panattoni GL. «Chordoid tissue»: biological significance and relevance of the term. Boll Soc Ital Biol Sper. 1993;69:315-319.