메뉴 건너뛰기




Volumn 11, Issue 4, 2005, Pages 312-317

Metabolic and endocrine effects of sedative agents

Author keywords

Hormones; Metabolism; Sedative and analgesic drugs; Stress response

Indexed keywords

ANALGESIC AGENT; BENZODIAZEPINE; CATECHOLAMINE DERIVATIVE; CLONIDINE; CORTICOTROPIN; DEXMEDETOMIDINE; DOPAMINE; ETOMIDATE; FENTANYL; GROWTH HORMONE; HYDROCORTISONE; INSULIN; KETAMINE; MELATONIN; MIDAZOLAM; MORPHINE; OPIATE; PROPOFOL; THYROID HORMONE;

EID: 24344486107     PISSN: 10705295     EISSN: 15317072     Source Type: Journal    
DOI: 10.1097/01.ccx.0000166397.50517.1f     Document Type: Review
Times cited : (27)

References (45)
  • 1
    • 0031732506 scopus 로고    scopus 로고
    • Acute and prolonged critical illness as different neuroendocrine paradigms
    • Van den Berghe G, de Zegher F, Bouillon R. Acute and prolonged critical illness as different neuroendocrine paradigms. J Clin Endocrinol Metab 1998; 83:1827-1834.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1827-1834
    • Van Den Berghe, G.1    De Zegher, F.2    Bouillon, R.3
  • 2
    • 0018671513 scopus 로고
    • Alterations in metabolism following injury: Part II
    • Cuthbertson DP. Alterations in metabolism following injury: part II. Injury 1980; 11:175-179.
    • (1980) Injury , vol.11 , pp. 175-179
    • Cuthbertson, D.P.1
  • 3
    • 0029788739 scopus 로고    scopus 로고
    • Critical illness is associated with low circulating concentrations of insulin-like growth factors-I and II, alterations in insulin-like growth factor binding proteins, and induction of an insulin-like growth factor binding protein 3 protease
    • Timmins AC, Cotterill AM, Cwyfan Hughes SC, et al. Critical illness is associated with low circulating concentrations of insulin-like growth factors-I and II, alterations in insulin-like growth factor binding proteins, and induction of an insulin-like growth factor binding protein 3 protease. Crit Care Med 1996; 24:1460-1466.
    • (1996) Crit Care Med , vol.24 , pp. 1460-1466
    • Timmins, A.C.1    Cotterill, A.M.2    Cwyfan Hughes, S.C.3
  • 4
    • 0036920935 scopus 로고    scopus 로고
    • Regulation of insulin-like growth factor binding protein-1 during protracted critical illness
    • Mesotten D, Delhanty PJD, Vanderhoydonc F, et al. Regulation of insulin-like growth factor binding protein-1 during protracted critical illness. J Clin Endocrinol Metab 2002; 87:5516-5523.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5516-5523
    • Mesotten, D.1    Delhanty, P.J.D.2    Vanderhoydonc, F.3
  • 5
    • 0036037553 scopus 로고    scopus 로고
    • Endocrine measurements in survivors and non survivors from critical illness
    • Ray DC, Macduff A, Drummond GB, et al. Endocrine measurements in survivors and non survivors from critical illness. Intensive Care Med 2002; 28:1301-1308.
    • (2002) Intensive Care Med , vol.28 , pp. 1301-1308
    • Ray, D.C.1    Macduff, A.2    Drummond, G.B.3
  • 6
    • 0034085077 scopus 로고    scopus 로고
    • Plasma cortisol is often decreased in patients treated in an intensive care unit
    • Rydvall A, Brandstrom AK, Banga R, et al. Plasma cortisol is often decreased in patients treated in an intensive care unit. Intensive Care Med 2000; 26:545-551.
    • (2000) Intensive Care Med , vol.26 , pp. 545-551
    • Rydvall, A.1    Brandstrom, A.K.2    Banga, R.3
  • 7
    • 0035097604 scopus 로고    scopus 로고
    • Adrenal insufficiency in high-risk surgical ICU patients
    • Rivers EP, Gaspari M, Saad GA, et al. Adrenal insufficiency in high-risk surgical ICU patients. Chest 2001; 119:889-896.
    • (2001) Chest , vol.119 , pp. 889-896
    • Rivers, E.P.1    Gaspari, M.2    Saad, G.A.3
  • 8
    • 0028902595 scopus 로고
    • Effects of human growth hormone in critically ill non-septic patients: Results from a prospective, randomized, placebo-controlled trial
    • Voerman BJ, Van Schijndel RJMS, Groeneveld ABJ, et al. Effects of human growth hormone in critically ill non-septic patients: results from a prospective, randomized, placebo-controlled trial. Crit Care Med 1995; 23:665-673.
    • (1995) Crit Care Med , vol.23 , pp. 665-673
    • Voerman, B.J.1    Van Schijndel, R.J.M.S.2    Groeneveld, A.B.J.3
  • 9
    • 0033539018 scopus 로고    scopus 로고
    • Increased mortality associated with growth hormone treatment in critically ill adults
    • Takala J, Esko R, Nigel RW, et al. Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med 1999; 341:785-792.
    • (1999) N Engl J Med , vol.341 , pp. 785-792
    • Takala, J.1    Esko, R.2    Nigel, R.W.3
  • 10
    • 0030961983 scopus 로고    scopus 로고
    • Urine and plasma catecholamine and cortisol concentrations after myocardial revascularization: Modulation by continuous sedation
    • Plunkett JJ, Reeves JD, Ngo L, et al. Urine and plasma catecholamine and cortisol concentrations after myocardial revascularization: modulation by continuous sedation. Anesthesiology 1997; 86:785-796.
    • (1997) Anesthesiology , vol.86 , pp. 785-796
    • Plunkett, J.J.1    Reeves, J.D.2    Ngo, L.3
  • 11
    • 1842844354 scopus 로고    scopus 로고
    • Sleep disruption in critically ill patients: Pharmacological considerations
    • Bourne RS, Mills GH. Sleep disruption in critically ill patients: pharmacological considerations. Anaesthesia 2004; 59:374-384.
    • (2004) Anaesthesia , vol.59 , pp. 374-384
    • Bourne, R.S.1    Mills, G.H.2
  • 12
    • 3142777652 scopus 로고    scopus 로고
    • Low melatonin excretion during mechanical ventilation in the intensive care unit
    • Frisk U, Olsson J, Nylen P, et al. Low melatonin excretion during mechanical ventilation in the intensive care unit. Clin Sci 2004; 107:47-53. Disruption of sleep in common in intensive care, and the pattern of melatonin secretion has been associated with disturbed sleep. The choice of sedatives used in intensive care does not seem to have a major influence on the melatonin level. Supplementation of melatonin might correct the hyposecretion and probably enhance the pulsatile secretion of growth hormone and prolactin.
    • (2004) Clin Sci , vol.107 , pp. 47-53
    • Frisk, U.1    Olsson, J.2    Nylen, P.3
  • 13
    • 3042570072 scopus 로고    scopus 로고
    • Abolished circadian rhythm of melatonin secretion in sedated and artificially ventilated intensive care patients
    • Olofsson K, Alling C, Lundberg D, et al. Abolished circadian rhythm of melatonin secretion in sedated and artificially ventilated intensive care patients. Acta Anaesthesiol Scand 2004; 48:679-684.
    • (2004) Acta Anaesthesiol Scand , vol.48 , pp. 679-684
    • Olofsson, K.1    Alling, C.2    Lundberg, D.3
  • 14
    • 0038796643 scopus 로고    scopus 로고
    • Correlation between serum melatonin circadian rhythm and intensive care unit psychosis after thoracic esophagectomy
    • Miyazaky T, Hiroyuki K, Hiroyuki K, et al. Correlation between serum melatonin circadian rhythm and intensive care unit psychosis after thoracic esophagectomy. Surgery 2003; 133:662-668.
    • (2003) Surgery , vol.133 , pp. 662-668
    • Miyazaky, T.1    Hiroyuki, K.2    Hiroyuki, K.3
  • 15
    • 0034856006 scopus 로고    scopus 로고
    • Acute pain induces insulin resistance in humans
    • Greisen J, Claus BJ, Thorbjorn G, et al. Acute pain induces insulin resistance in humans. Anesthesiology 2001; 95:578-584.
    • (2001) Anesthesiology , vol.95 , pp. 578-584
    • Greisen, J.1    Claus, B.J.2    Thorbjorn, G.3
  • 16
    • 0345346382 scopus 로고    scopus 로고
    • Postoperative pain and subcutaneous oxygen tension
    • Akca O, Melischek M, Scheck T, et al. Postoperative pain and subcutaneous oxygen tension. Lancet 1999; 354:41-42.
    • (1999) Lancet , vol.354 , pp. 41-42
    • Akca, O.1    Melischek, M.2    Scheck, T.3
  • 17
    • 0013826260 scopus 로고
    • An experimental study of atypical phantom pain
    • Pilowsky I, Kaufman A. An experimental study of atypical phantom pain. Br J Psychiatry 1965; 111:1185-1187.
    • (1965) Br J Psychiatry , vol.111 , pp. 1185-1187
    • Pilowsky, I.1    Kaufman, A.2
  • 18
    • 3242685073 scopus 로고    scopus 로고
    • Analgesia and sedation in critically ill patients
    • Walder B, Tramer MR. Analgesia and sedation in critically ill patients. Swiss Med Wkly 2004; 134:333-346.
    • (2004) Swiss Med Wkly , vol.134 , pp. 333-346
    • Walder, B.1    Tramer, M.R.2
  • 19
    • 0036152552 scopus 로고    scopus 로고
    • Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult
    • Jacobi J, Gilles LF, Douglas BC, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med 2002; 30:119-141.
    • (2002) Crit Care Med , vol.30 , pp. 119-141
    • Jacobi, J.1    Gilles, L.F.2    Douglas, B.C.3
  • 20
    • 0023713381 scopus 로고
    • Effect of patient-controlled analgesia on plasma catecholamine, cortisol and glucose concentrations after cholecystectomy
    • Moller IW, Dinesen K, Sondergard S, et al. Effect of patient-controlled analgesia on plasma catecholamine, cortisol and glucose concentrations after cholecystectomy. Br J Anaesth 1988; 61:160-164.
    • (1988) Br J Anaesth , vol.61 , pp. 160-164
    • Moller, I.W.1    Dinesen, K.2    Sondergard, S.3
  • 21
    • 0022644254 scopus 로고
    • Midazolam infusion for sedation in the intensive care unit: Effect on adrenal function
    • Shapiro JM, Westphal LM, White PF, et al. Midazolam infusion for sedation in the intensive care unit: effect on adrenal function. Anesthesiology 1986; 64:394-398.
    • (1986) Anesthesiology , vol.64 , pp. 394-398
    • Shapiro, J.M.1    Westphal, L.M.2    White, P.F.3
  • 22
    • 0025284664 scopus 로고
    • Plasma catecholamine concentration during sedation in ventilated patients requiring intensive therapy
    • Kong KL, Wilatts SM, Prys-Roberts C, et al. Plasma catecholamine concentration during sedation in ventilated patients requiring intensive therapy. Intensive Care Med 1990; 16:171-174.
    • (1990) Intensive Care Med , vol.16 , pp. 171-174
    • Kong, K.L.1    Wilatts, S.M.2    Prys-Roberts, C.3
  • 23
    • 0033995087 scopus 로고    scopus 로고
    • Cardiovascular response and stress reaction to flumazenil injection in patients under infusion with midazolam
    • Kamijo Y, Masuda T, Nishikawa T, et al. Cardiovascular response and stress reaction to flumazenil injection in patients under infusion with midazolam. Crit Care Med 2000; 28:318-323.
    • (2000) Crit Care Med , vol.28 , pp. 318-323
    • Kamijo, Y.1    Masuda, T.2    Nishikawa, T.3
  • 24
    • 0034026779 scopus 로고    scopus 로고
    • Sedation in the intensive care unit
    • Young C, Knudsen N, Hilton A, et al. Sedation in the intensive care unit. Crit Care Med 2000; 28:854-866.
    • (2000) Crit Care Med , vol.28 , pp. 854-866
    • Young, C.1    Knudsen, N.2    Hilton, A.3
  • 25
    • 0028879080 scopus 로고
    • Polyethylene glycol nephrotoxicity secondary to prolonged high-dose intravenous lorazepam
    • Laine GA, Hossain SM, Sous RT, et al. Polyethylene glycol nephrotoxicity secondary to prolonged high-dose intravenous lorazepam. Ann Pharmacother 1995; 29:1110-1114.
    • (1995) Ann Pharmacother , vol.29 , pp. 1110-1114
    • Laine, G.A.1    Hossain, S.M.2    Sous, R.T.3
  • 26
    • 0031919534 scopus 로고    scopus 로고
    • Acute withdrawal syndrome related to the administration of analgesics and sedative medications in adult intensive care unit patients
    • Cammarano WB, Pittet JF, Weitz S, et al. Acute withdrawal syndrome related to the administration of analgesics and sedative medications in adult intensive care unit patients. Crit Care Med 1998; 26:676-684.
    • (1998) Crit Care Med , vol.26 , pp. 676-684
    • Cammarano, W.B.1    Pittet, J.F.2    Weitz, S.3
  • 27
    • 0031898657 scopus 로고    scopus 로고
    • Complications of sedation with midazolam in the intensive care unit and a comparison with other sedative regimens
    • Shafer A. Complications of sedation with midazolam in the intensive care unit and a comparison with other sedative regimens. Crit Care Med 1998; 26:947-956.
    • (1998) Crit Care Med , vol.26 , pp. 947-956
    • Shafer, A.1
  • 28
    • 0022551865 scopus 로고
    • Withdrawal reaction after long-term therapeutic use of benzodiazepines
    • Busto U, Sellers EM, Naranjo CA, et al. Withdrawal reaction after long-term therapeutic use of benzodiazepines. N Engl J Med 1986; 315:854-859.
    • (1986) N Engl J Med , vol.315 , pp. 854-859
    • Busto, U.1    Sellers, E.M.2    Naranjo, C.A.3
  • 29
    • 0023808026 scopus 로고
    • Prolonged sedation with propofol in ICU patients: Recovery and blood concentration changes during periodic interruptions in infusion
    • Beller JP, Pottecher T, Lugnier A, et al. Prolonged sedation with propofol in ICU patients: recovery and blood concentration changes during periodic interruptions in infusion. Br J Anaesth 1988; 61:583-588.
    • (1988) Br J Anaesth , vol.61 , pp. 583-588
    • Beller, J.P.1    Pottecher, T.2    Lugnier, A.3
  • 30
    • 0035076456 scopus 로고    scopus 로고
    • A lack of evidence of superiority of propofol versus midazolam for sedation in mechanically ventilated critically ill patients: A qualitative and quantitative systematic review
    • Walder B, Elia N, Henzi I, et al. A lack of evidence of superiority of propofol versus midazolam for sedation in mechanically ventilated critically ill patients: a qualitative and quantitative systematic review. Anesth Analg 2001; 92:975-983.
    • (2001) Anesth Analg , vol.92 , pp. 975-983
    • Walder, B.1    Elia, N.2    Henzi, I.3
  • 31
    • 0036884231 scopus 로고    scopus 로고
    • Sedation during mechanical ventilation: A systematic review
    • Izurieta R, Rabatin JT. Sedation during mechanical ventilation: a systematic review. Crit Care Med 2002; 30:2644-2648.
    • (2002) Crit Care Med , vol.30 , pp. 2644-2648
    • Izurieta, R.1    Rabatin, J.T.2
  • 32
    • 0024442964 scopus 로고
    • Comparison of propofol and midazolam for sedation in critically ill patients
    • Aitkenhead AR, Pepperman ML, Willatts SM, et al. Comparison of propofol and midazolam for sedation in critically ill patients. Lancet 1989; 2:704-709.
    • (1989) Lancet , vol.2 , pp. 704-709
    • Aitkenhead, A.R.1    Pepperman, M.L.2    Willatts, S.M.3
  • 33
    • 0037241146 scopus 로고    scopus 로고
    • Propofol: A review of its use in intensive care sedation of adults
    • McCage K, Perry C. Propofol: a review of its use in intensive care sedation of adults. CNS Drugs 2003; 17:235-272.
    • (2003) CNS Drugs , vol.17 , pp. 235-272
    • McCage, K.1    Perry, C.2
  • 34
    • 0033383616 scopus 로고    scopus 로고
    • Propofol for sedation in the intensive care unit: Comparative evaluation of 1% and 2% formulations
    • Montanini S, Pratico C, Tufano R, et al. Propofol for sedation in the intensive care unit: comparative evaluation of 1% and 2% formulations. Br J Intensive Care 1999; 9:110-114.
    • (1999) Br J Intensive Care , vol.9 , pp. 110-114
    • Montanini, S.1    Pratico, C.2    Tufano, R.3
  • 35
    • 0035110147 scopus 로고    scopus 로고
    • Pharmacoeconomic assessment of propofol 2% used for prolonged sedation
    • Barrientos-Vega R, Sanchez-Soria M, Morales-Garcia C, et al. Pharmacoeconomic assessment of propofol 2% used for prolonged sedation. Crit Care Med 2001; 29:317-322.
    • (2001) Crit Care Med , vol.29 , pp. 317-322
    • Barrientos-Vega, R.1    Sanchez-Soria, M.2    Morales-Garcia, C.3
  • 36
    • 0035195635 scopus 로고    scopus 로고
    • Metabolic acidosis, rhabdomyolysis, and cardiovascular collapse after prolonged propofol infusion
    • Cannon ML, Glazier SS, Bauman LA. Metabolic acidosis, rhabdomyolysis, and cardiovascular collapse after prolonged propofol infusion. J Neurosurg 2001; 95:1053-1056.
    • (2001) J Neurosurg , vol.95 , pp. 1053-1056
    • Cannon, M.L.1    Glazier, S.S.2    Bauman, L.A.3
  • 37
    • 0141789591 scopus 로고    scopus 로고
    • The pathophysiology of propofol infusion syndrome: A simple name for a complex syndrome
    • Vasile B, Rasulo F, Candiani A, et al. The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. Intensive Care Med 2003; 29:1417-1425.
    • (2003) Intensive Care Med , vol.29 , pp. 1417-1425
    • Vasile, B.1    Rasulo, F.2    Candiani, A.3
  • 38
    • 0035941743 scopus 로고    scopus 로고
    • Impaired fatty acid oxidation in propofol infusion syndrome
    • Wolf A, Weir P, Segar P, et al. Impaired fatty acid oxidation in propofol infusion syndrome. Lancet 2001; 357:606-607.
    • (2001) Lancet , vol.357 , pp. 606-607
    • Wolf, A.1    Weir, P.2    Segar, P.3
  • 39
    • 0035852482 scopus 로고    scopus 로고
    • Long-term propofol infusion and cardiac failure in adult head-injured patients
    • Cremer OL, Moons KGM, Bouman EAC, et al. Long-term propofol infusion and cardiac failure in adult head-injured patients. Lancet 2001; 357:117-118.
    • (2001) Lancet , vol.357 , pp. 117-118
    • Cremer, O.L.1    Moons, K.G.M.2    Bouman, E.A.C.3
  • 40
    • 0035203606 scopus 로고    scopus 로고
    • Propofol infusion syndrome
    • Kelly DF. Propofol infusion syndrome. J Neurosurg 2001;925-926.
    • (2001) J Neurosurg , pp. 925-926
    • Kelly, D.F.1
  • 41
    • 0035030213 scopus 로고    scopus 로고
    • Effects of dexmedetomidine on adrenocortical function, ad the cardiovascular, endocrine and inflammatory responses in post-operative patients needing sedation in intensive care unit
    • Venn RM, Bryant A, Hall GM, et al. Effects of dexmedetomidine on adrenocortical function, ad the cardiovascular, endocrine and inflammatory responses in post-operative patients needing sedation in intensive care unit. Br J Anaesth 2001; 86:650-656.
    • (2001) Br J Anaesth , vol.86 , pp. 650-656
    • Venn, R.M.1    Bryant, A.2    Hall, G.M.3
  • 42
    • 0023502606 scopus 로고
    • Reduced narcotic requirement by clonidine with improved hemodynamic and adrenergic stability in patients undergoing coronary bypass surgery
    • Flacke JW, Bloor BC, Flacke WE, et al. Reduced narcotic requirement by clonidine with improved hemodynamic and adrenergic stability in patients undergoing coronary bypass surgery. Anesthesiology 1987; 67:11-19.
    • (1987) Anesthesiology , vol.67 , pp. 11-19
    • Flacke, J.W.1    Bloor, B.C.2    Flacke, W.E.3
  • 43
    • 0345269259 scopus 로고    scopus 로고
    • Clonidine premedication improves metabolic control in type 2 diabetic patients during ophthalmic surgery
    • Belhoula M, Ciebiera JP, De La Chapelle A, et al. Clonidine premedication improves metabolic control in type 2 diabetic patients during ophthalmic surgery. Br J Anaesth 2003; 90:434-439.
    • (2003) Br J Anaesth , vol.90 , pp. 434-439
    • Belhoula, M.1    Ciebiera, J.P.2    De La Chapelle, A.3
  • 44
    • 0021604882 scopus 로고
    • Mortality amongst multiple trauma patients admitted to an intensive therapy unit
    • Watt I, Ledingham IM. Mortality amongst multiple trauma patients admitted to an intensive therapy unit. Anaesthesia 1984; 39:973-981.
    • (1984) Anaesthesia , vol.39 , pp. 973-981
    • Watt, I.1    Ledingham, I.M.2
  • 45
    • 0032884057 scopus 로고    scopus 로고
    • Adrenocortical function in critically ill patients 24h after a single dose of etomidate
    • Absalom A, Pledger D, Kong A. Adrenocortical function in critically ill patients 24h after a single dose of etomidate. Anaesthesia 1999; 54:861-867.
    • (1999) Anaesthesia , vol.54 , pp. 861-867
    • Absalom, A.1    Pledger, D.2    Kong, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.