Plasminogen activator/plasmin system suppresses cell-cell adhesion of oral squamous cell carcinoma cells via proteolysis of E-cadherin

International Journal of Oncology

Volumn 27, Issue 3, 2005, Pages 693-698

  Hayashido, Yasutaka ^a   Hamana, Tomoaki ^a   Yoshioka, Yukio ^a   Kitano, Hisataka ^a   Koizumi, Koh Ichi ^a   Okamoto, Tetsuji ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Cell cell adhesion; E cadherin; Motility; Plasminogen activator plasmin system; Squamous cell carcinoma

Indexed keywords

CADHERIN; CALCIUM; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR;

ARTICLE; CELL ADHESION; CELL MOTION; DOSE RESPONSE; DRUG EFFECT; HUMAN; METABOLISM; MOUTH TUMOR; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SQUAMOUS CELL CARCINOMA; TIME; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CADHERINS; CALCIUM; CARCINOMA, SQUAMOUS CELL; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MOUTH NEOPLASMS; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATORS; TIME FACTORS;

EID: 24344485538     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Takeichi M: Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251: 1451-1455, 1991.
2. Gumbiner BM: Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84: 345-357, 1996.
3. Shiozaki H, Tahara H, Oka H, Miyata M, Kobayashi K, Tamura S, lihara K, Doki Y, Hirano S and Takeichi M: Expression of immunoreactive E-cadherin adhesion molecules in human cancers. Am J Pathol 139: 17-23, 1991.
4. Furukawa F, Takigawa M, Matsuyoshi N, Shirahama S, Wakita H, Fujita M, Horiguchi Y and Imamura S: Cadherins in cutaneous biology. J Dermatol 21: 802-813, 1994.
5. Pignatelli M, Ansari TW, Gunter P, Liu D, Hirano S, Takeichi M, Kloppel G and Lemoine NR: Loss of membranous E-cadherin expression in pancreatic cancer: correlation with lymph node metastasis, high grade, and advanced stage. J Pathol 174: 243-248, 1994.
6. Vessey CJ, Wilding J, Folarin N, Hirano S, Takeichi M, Soutter P, Stamp GW and Pignatelli M: Altered expression and function of E-cadherin in cervical intraepithelial neoplasia and invasive squamous cell carcinoma. J Pathol 176: 151-159, 1995.
7. Berx G, Becker KF, Holler H and van Roy F: Mutations of the human E-cadherin (CDH1) gene. Hum Mutat 12: 226-237, 1998.
8. Hirohashi S: Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am J Pathol 153: 333-339, 1998.
9. Tryggvason K, Höyhtyä K and Salo T: Proteolytic degradation of extracellular matrix in tumor invasion. Biochim Biophys Acta 907: 191-217, 1987.
10. Mayer M: Biochemical and biological aspects of the plasminogen activation system. Clin Biochem 23: 197-211, 1990.
11. Baramova EN, Bajou K, Remade A, L'Hoir C, Krell HW, Weidle UH, Noel A and Foidart JM: Involvement of PA/plasmin system in the processing of pro-MMP-9 and in the second step of pro-MMP-2 activation. FEBS Lett 405: 157-162, 1997.
12. Hayashido Y, Shirasuna K and Matsuya T: Effect of epidermal growth factor on invasion of human squamous cell carcinoma cells into collagen gel. Cancer J 4: 257-261, 1991.
13. Hayashido Y, Shirasuna K, Sugiura T, Nakashima M and Matsuya T: Effect of dexamethasone on invasion of human squamous cell carcinoma cell into collagen gel. Cancer Letter 108:81-86, 1996.
14. Endo A, Nagai N, Urano T, lhara H, Takada Y, Hashimoto K and Takada A: Proteolysis of highly polysialylated NCAM by the tissue plasminogen activator-plasmin system in rats. Neurosci Lett 246: 37-40, 1998.
15. Nayeem N, Silletti S, Yang X, Lemmon VP, Reisfeld RA, Stallcup WB and Montgomery AM: A potential role for the plasmin(ogen) system in the post-translational cleavage of the neural cell adhesion molecule LI. J Cell Sci 112: 4739-4749, 1999.
16. Quinton TM, Kim S, Derian CK, Jin J and Kunapuli SP: Plasminmediated activation of platelets occurs by cleavage of proteaseactivated receptor 4. J Biol Chem 279: 18434-18439, 2004.
17. Paradies NE and Grunwald GB: Purification and characterization of NCAD90, a soluble endogenous form of N-cadherin, which is generated by proteolysis during retinal development and retains adhesive and neurite-promoting function. J Neurosci Res 36: 33-45, 1993.
18. Couet J, Sar S, Jolivet A, Hai MT, Milgrom E and Misrahi M: Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease. J Biol Chem 271: 4545-4552, 1996.
19. Herren B, Levkau B, Raines EW and Ross R: Cleavage of betacatenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases. Mol Biol Cell 9: 1589-1601, 1998.
20. Nath D, Williamson NJ, Jarvis R and Murphy G: Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase. J Cell Sci 114: 1213-1220, 2001.
21. Deryugina EI, Ratnikov BI, Postnova TI, Rozanov DV and Strongin AY: Processing of integrin alpha(v) subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase. J Biol Chem 277: 9749-9756, 2002.
22. Damsky CH, Richa J, Solter D, Knudsen K and Buck CA: Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissue. Cell 34: 455-466, 1983.
23. Katayama M, Hirai S, Kamihagi K, Nakagawa K, Yasumoto M and Kato I: Soluble E-cadherin fragments increased in circulation of cancerpatients. Br J Cancer 69: 580-585, 1994.
24. Griffiths TR, Brotherick I, Bishop RI, White MD, McKenna DM, Horne CH, Shenton BK, Neal DE and Mellon JK: Cell adhesion molecules in bladder cancer: soluble serum E-cadherin correlates with predictors of recurrence. Br J Cancer 74: 579-584, 1996.
25. Gofuku J, Shiozaki H, Doki Y, Inoue M, Hirao M, Fukuchi N and Monden M: Characterization of soluble E-cadherin as a disease marker in gastric cancer patients. Br J Cancer 78: 1095-1101,1998.
26. Lochter A, Galosy S, Muschler J, Freedman N, Werb Z and Bissell MJ: Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelialto- mesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J Cell Biol 139: 1861-1872, 1997.
27. Noe V, Fingleton B, Jacobs K, Crawford HC, Vermeulen S, Steelant W, Bruyneel E, Matrisian LM and Mareel M: Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1. J Cell Sci 114: 111-118, 2001.
28. Sugiura T, Shirasuna K, Hayashido Y, Sakai T and Matsuya M: Effects of human fibroblasts on invasiveness of oral cancer cells in vitro: isolation of a chemotactic factor from human fibroblasts. Int J Cancer 68: 774-781, 1996.
29. Hayashido Y, Lucas A, Rougeot C, Godyna S, Argraves WS and Rochefort H: Estradiol and fibulin-1 inhibit motility of human ovarian- and breast-cancer cells induced by fibronectin. Int J Cancer 75: 654-658, 1998.
30. Testa JE and Quigley JP: The role of urokinase-type plasminogen activator in aggressive tumor cell behavior. Cancer Metastasis Rev 9: 353-367, 1990.
31. Gröndahl HJ, Christensen IJ, Rosenquist C, Briinner N, Mouridsen HT, Dano K and Blichert TM: High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis. Cancer Res 53: 2513-2521, 1993.
32. Andreasen PA, Kjolier L, Christensen L and Duffy MJ: The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer 72: 1-22, 1997.
33. De Petro G, Tavian D, Copeta A, Portolani N, Giulini SM and Barlati S: Expression of urokinase-type plasminogen activator (u-PA), u-PA receptor, and tissue-type PA messenger RNAs in human hepatocellular carcinoma. Cancer Res 58: 2234-2239, 1998.
34. Ito K, Okamoto I, Araki N, Kawano Y, Nakao M, Fujiyama S, Tomita K, Mimori T and Saya H: Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts. Oncogene 18: 7080-7090, 1999.