Characterization of a novel protein from Proatheris superciliaris venom: Proatherocytin, a 34-kDa platelet receptor PAR1 agonist

Toxicon

Volumn 46, Issue 5, 2005, Pages 490-499

  Laing, Gavin D ^a   Compton, Steven J ^b   Ramachandran, Rithwik ^b   Fuller, Gemma L J ^c   Wilkinson, Mark C ^d   Wagstaff, Simon C ^a   Watson, Stephen P ^c   Kamiguti, Aura S ^d   Theakston, R David G ^a   Senis, Yotis A ^c  

^a LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^b CASTLE HILL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Aggregation; PAR1 agonist; Platelet; Proatheris superciliaris; Thrombin; Venom

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; 4 AMINO 5 METHYLPHENYL 7 BUTYLPYRAZOLO 3,4 DIPYRIMIDINE; ENZYME PROATHEROCYTIN; FIBRINOGEN; G PROTEIN COUPLED RECEPTOR; METALLOPROTEINASE; PROTEIN TYROSINE KINASE INHIBITOR; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VENOM;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BLOOD CLOTTING; CELL SHAPE; CELL STIMULATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME SUBSTRATE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN INDUCTION; RAT; SEQUENCE HOMOLOGY; SNAKE; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

AMINO ACID SEQUENCE; ANIMALS; BLOOD COAGULATION; BLOOD PLATELETS; CALCIUM SIGNALING; COLORIMETRY; EPITHELIAL CELLS; HEMORRHAGE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PLATELET AGGREGATION; RATS; RECEPTOR, PAR-1; SERINE ENDOPEPTIDASES; SRC-FAMILY KINASES; VIPER VENOMS;

BOVINAE; PROATHERIS SUPERCILIARIS; VIPER; VIPERIDAE;

EID: 24344480512     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2005.06.011     Document Type: Article

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