An ionic model of stretch-activated and stretch-modulated currents in rabbit ventricular myocytes

Europace

Volumn 7, Issue SUPPL. 2, 2005, Pages

  Healy, Sarah N ^a   McCulloch, Andrew D ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Rabbit cardiomyocyte; Stretch activated channels; Transmural heterogeneity

Indexed keywords

CATION; ION CHANNEL; POTASSIUM ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENSITY; ENDOCARDIUM; EPICARDIUM; EXPERIMENTATION; HEART CONDUCTION; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEART VENTRICLE; MEMBRANE POTENTIAL; MODULATION; MOLECULAR MODEL; MUSCLE STRETCHING; NONHUMAN; OBSERVATION; POTASSIUM CURRENT; PREDICTION; PRIORITY JOURNAL; RABBIT; SENSITIVITY ANALYSIS;

ACTION POTENTIALS; ANIMALS; COMPUTER SIMULATION; HEART CONDUCTION SYSTEM; HEART VENTRICLES; ION CHANNELS; MYOCYTES, CARDIAC; RABBITS; STRESS, MECHANICAL;

EID: 24344438945     PISSN: 10995129     EISSN: 15322092     Source Type: Journal    
DOI: 10.1016/j.eupc.2005.03.019     Document Type: Article

References (26)

1. T.L. Riemer E.A. Sobie L. Tung Stretch-induced changes in arrhythmogenesis and excitability in experimentally based heart cell models Am J Physiol Heart Circ Physiol 275 2 1998 H431-H442
2. M.R. Franz R. Cima D. Wang D. Profitt R. Kurz Electrophysiological effects of myocardial stretch and mechanical determinants of stretch-activated arrhythmias Circulation 86 3 1992 968-978
3. c in ventricular myocytes Prog Biophys Mol Biol 82 1-3 2003 43-56
4. F. Guharay F. Sachs Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle J Physiol 352 1984 685-701
5. T. Zeng G.C.L. Bett F. Sachs Stretch-activated whole cell currents in adult rat cardiac myocytes Am J Physiol Heart Circ Physiol 278 2 2000 H548-H557
6. M. Zabel B.S. Koller F. Sachs M.R. Franz Stretch-induced voltage changes in the isolated beating heart: Importance of the timing of stretch and implications for stretch-activated ion channels Cardiovasc Res 32 1 1996 120-130
7. Y.H. Zhang J.B. Youm H.K. Sung S.H. Lee S.Y. Ryu S.-H. Lee et al. Stretch-activated and background non-selective cation channels in rat atrial myocytes J Physiol (Lond) 523 3 2000 607-619
8. B.B. Lerman E.D. Engelstein D. Burkhoff Mechanoelectrical feedback: Role of beta-adrenergic receptor activation in mediating load-dependent shortening of ventricular action potential and refractoriness Circulation 104 4 2001 486-490
9. H. Hu F. Sachs Stretch-activated ion channels in the heart J Mol Cell Cardiol 29 6 1997 1511-1523
10. D.M. Browe C.M. Baumgarten Stretch of beta1 integrin activates an outwardly rectifying chloride current via FAK and Src in rabbit ventricular myocytes J Gen Physiol 122 6 2003 689-702
11. J.H.C. Tan W. Liu D.A. Saint Differential expression of the mechanosensitive potassium channel TREK-1 in epicardial and endocardial myocytes in rat ventricle Exp Physiol 89 3 2004 237-242
12. C.-H. Luo Y. Rudy A dynamic model of the cardiac ventricular action potential I. Simulations of ionic currents and concentration changes Circ Res 74 1994 1071-1096
13. J.L. Puglisi D.M. Bers LabHEART: An interactive computer model of rabbit ventricular myocyte ion channels and Ca transport Am J Physiol Cell Physiol 281 6 2001 C2049-C2060
14. J.L. Puglisi F. Wang D.M. Bers Modeling the isolated cardiac myocyte Prog Biophys Mol Biol 85 2-3 2004 163-178
15. J.J. Saucerman S.N. Healy M.E. Belik J.L. Puglisi A.D. McCulloch Proarrhythmic consequences of a KCNQ1 AKAP-binding domain mutation: computational models of whole cells and heterogeneous tissue Circ Res 95 12 2004 1216-1224
16. D. Sung R.W. Mills J. Schettler S.M. Narayan J.H. Omens A.D. McCulloch Ventricular filling slows epicardial conduction and increases action potential duration in an optical mapping study of the isolated rabbit heart J Cardiovasc Electrophysiol 14 7 2003 739-749
17. J. Lekven K. Chatterjee J. Tyberg W. Parmley Reduction in ventricular endocardial and epicardial potentials during acute increments in left ventricular dimensions Am Heart J 98 2 1979 200-206
18. Y. Wu M.E. Anderson Reduced repolarization reserve in ventricular myocytes from female mice Cardiovasc Res 53 3 2002 763-769
19. F.G. Akar G.-X. Yan C. Antzelevitch D.S. Rosenbaum Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome Circulation 105 10 2002 1247-1253
20. W.S. Redfern L. Carlsson A.S. Davis W.G. Lynch I. MacKenzie S. Palethorpe et al. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: Evidence for a provisional safety margin in drug development Cardiovasc Res 58 1 2003 32-45
21. I. Libbus D.S. Rosenbaum Transmural action potential changes underlying ventricular electrical remodeling J Cardiovasc Electrophysiol 14 4 2003 394-405
22. S. Sicouri C. Antzelevitch A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle. The M cell Circ Res 68 6 1991 1729-1741
23. F.J. Vetter A.D. McCulloch Mechanoelectric feedback in a model of the passively inflated left ventricle Ann Biomed Eng 29 5 2001 414-426
24. K.J. Sampson C.S. Henriquez Simulation and prediction of functional block in the presence of structural and ionic heterogeneity Am J Physiol Heart Circ Physiol 281 6 2001 H2597-H2603
25. E.M. Cherry F.H. Fenton Suppression of alternans and conduction blocks despite steep APD restitution: Electrotonic, memory, and conduction velocity restitution effects Am J Physiol Heart Circ Physiol 286 6 2004 H2332-H2341
26. D. Kondratev M.F. Gallitelli Increments in the concentrations of sodium and calcium in cell compartments of stretched mouse ventricular myocytes Cell Calcium 34 2 2003 193-203