Preferential π-π complexation between tamoxifen and borage oil/γ linolenic acid: Transcutaneous delivery and NMR spectral modulation

International Journal of Pharmaceutics

Volumn 302, Issue 1-2, 2005, Pages 47-55

  Heard, Charles M ^a   Gallagher, Simon J ^a   Congiatu, Costantino ^a   Harwood, John ^a   Thomas, Christopher P ^a   McGuigan, Christopher ^a   Němcová, Marta ^a   Nouskova, Tereza ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Linolenic acid; interactions; Borage oil; Complexation; GLA; NMR; Skin; Tamoxifen; Transcutaneous delivery; Vehicle

Indexed keywords

BORAGE OIL; GAMMA LINOLENIC ACID; LINOLEIC ACID; LIQUID PARAFFIN; MACROGOL 4000; MINERAL OIL; TAMOXIFEN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VEGETABLE OIL;

ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; GEL; IN VITRO STUDY; MOLECULAR INTERACTION; MOLECULAR PROBE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SKIN PERMEABILITY;

ADMINISTRATION, CUTANEOUS; ANIMALS; EAR, EXTERNAL; GAMMA-LINOLENIC ACID; GELS; MAGNETIC RESONANCE SPECTROSCOPY; PLANT OILS; SKIN; SKIN ABSORPTION; SWINE; TAMOXIFEN;

EID: 24144474257     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2005.06.013     Document Type: Article

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