Plasticity and reorganization of the uninjured brain

Topics in Stroke Rehabilitation

Volumn 12, Issue 3, 2005, Pages 1-10

  Bayona, Nestor A ^a   Bitensky, Jamie ^a,b   Teasell, Robert ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

Animal models; Cerebral cortex; Humans; Neuronal plasticity; Synapses

Indexed keywords

BODY MOVEMENT; BRAIN CORTEX; DENDRITE; EXPERIENCE; FORELIMB; HUMAN; LEARNING; MOTOR ACTIVITY; MUSCLE CONTRACTION; NERVE CELL; NERVE CELL PLASTICITY; NERVE FIBER GROWTH; NERVE STIMULATION; NEUROIMAGING; NONHUMAN; REVIEW; SENSORIMOTOR CORTEX; SENSORY NERVE CONDUCTION; SYNAPSE; SYNAPTIC TRANSMISSION;

ANIMALS; BRAIN INJURIES; CEREBRAL CORTEX; DENDRITIC CELLS; ENVIRONMENT; FORELIMB; HUMANS; LEARNING; MOTOR SKILLS; NEURONAL PLASTICITY;

EID: 24144467384     PISSN: 10749357     EISSN: None     Source Type: Journal    
DOI: 10.1310/A422-G91U-Q4HB-86XC     Document Type: Review

References (82)

1. Turkstra LS, Holland AL, Bays GA. The neuroscience of recovery and rehabilitation: What have we learned from animal research? Arch Phys Med Rehabil. 2003;84(4):604-612.
2. Rockel AJ, Hiorns RW, Powell TP. The basic uniformity in structure of the neocortex. Brain. 1980;103(2):221-244.
3. Kolb B. Brain Plasticity and Behavior. Mahwah, NJ: Lawrence Erlbaum; 1995.
4. Coleman PD, Buell SJ. Regulation of dendritic extent in developing and aging brain. In: Cotman CW, ed. Synoptic Plasticity. New York: Guilford Press; 1985:311-334.
5. Benavides-Piccione R, Ballesteros-Yanez I, DeFelipe J, Yuste R. Cortical area and species differences in dendritic spine morphology. J Neurocytol. 2002;31(3-5):337-346.
6. Valverde F. [Structure of the cerebral cortex. Intrinsic organization and comparative analysis of the neocortex]. Rev Neural. 2002;34(8):758-780.
7. Kovacs AD, Cebers G, Cebere A, Moreira T, Liljequist S. Cortical and striatal neuronal cultures of the same embryonic origin show intrinsic differences in glutamate receptor expression and vulnerability to excitotoxicity. Exp Neural 2001;168(1):47-62.
8. Gazzaniga MS. Neuroscience. Regional differences in cortical organization. Science. 2000;289(5486):1887-1888.
9. DeFelipe J, Elston GN, Fujita I, et al. Neocortical circuits: evolutionary aspects and specificity versus non-specificity of synaptic connections. Remarks, main conclusions and general comments and discussion. J Neurocytol. 2002;31(3-5):387-416.
10. Horner CH. Plasticity of the dendritic spine. Prog Neurobiol. 1993;41(3):281-321.
11. Kolb B, Gibb R. Environmental enrichment and cortical injury: behavioral and anatomical consequences of frontal cortex lesions. Cereb Cortex. 1991;1(2):189-198.
12. Kleim JA, Lussnig E, Schwarz ER, Comery TA, Greenough WT. Synaptogenesis and Fos expression in the motor cortex of the adult rat after motor skill learning. J Neurosci. 1996;16(14):4529-4535.
13. Ivanco TL, Racine RJ, Kolb B. Morphology of layer III pyramidal neurons is altered following induction of LTP in sensorimotor cortex of the freely moving rat. Synapse. 2000;37(1):16-22.
14. Toni N, Buchs PA, Nikonenko I, Bron CR, Muller D. LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite. Nature. 1999;402(6760):421-425.
15. Luscher C, Nicoll RA, Malenka RC, Muller D. Synaptic plasticity and dynamic modulation of the postsynaptic membrane. Nat Neurosci. 2000;3(6):545-550.
16. Muller CM. A role for glial cells in activity-dependent central nervous plasticity? Review and hypothesis. Int Rev Neurobiol. 1992;34:215-281.
17. Hebb DO. The Organization of Behavior: A Neuropsychologlcal Theory. New York: Wiley; 1949.
18. Diamond MC, Krech D, Rosenzweig MR. The effects of an enriched environment on the histology of the rat cerebral cortex. J Comp Neurol. 1964;123:111-120.
19. Greenough WT, Larson JR, Withers GS. Effects of unilateral and bilateral training in a reaching task on dendritic branching of neurons in the rat motorsensory forelimb cortex. Behav Neural Biol. 1985;44(2):301-314.
20. Rosenzweig MR, Bennett EL, Krech D. Cerebral effects of environmental complexity and training among adult rats. J Comp Physiol Psychol. 1964;57:438-439.
21. Diamond MC, Lindner B, Raymond A. Extensive cortical depth measurements and neuron size increases in the cortex of environmentally enriched rats. J Comp Neurol. 1967;131:357-364.
22. Rosenzweig MR, Krech D, Bennet EL, Diamond MC. Effects of environmental complexity and training on brain chemistry and anatomy: a replication and extension. J Comp Physiol Psychol. 1962;55:429-437.
23. Bennett EL, Diamond MC, Krech D, Rosenzweig MR. Chemical and anatomical plasticity brain. Science. 1964;146:610-619.
24. Globus A, Rosenzweig MR, Bennett EL, Diamond MC. Effects of differential experience on dendritic spine counts in rat cerebral cortex. J Comp Physiol Psychol. 1973;82(2):175-181.
25. Turner AM, Greenough WT. Differential rearing effects on rat visual cortex synapses. I. Synaptic and neuronal density and synapses per neuron. Brain Res. 1985;329(1-2):195-203.
26. Volkmar FR, Greenough WT. Rearing complexity affects branching of dendrites in the visual cortex of the rat. Science. 1972;176(42):1145-1147.
27. West RW, Greenough WT. Effect of environmental complexity on cortical synapses of rats: preliminary results. Behav Biol. 1972;7(2):279-284.
28. Rioult-Pedotti MS, Friedman D, Donoghue JP. Learning-induced LTP in neocortex. Science. 2000;290(5491):533-536.
29. Rioult MG, Kohen R, Barrett T. Learning induces widespread changes in gene expression in neocortex. Soc Neurosci Abstr. 2000;26:652-658.
30. Calverley RK, Jones DG. Contributions of dendritic spines and perforated synapses to synaptic plasticity. Brain Res Brain Res Rev. 1990;15(3):215-249.
31. Jones TA, Klintsova AY, Kilman VL, Sirevaag AM, Greenough WT. Induction of multiple synapses by experience in the visual cortex of adult rats. Neurobiol Learn Mem. 1997;68(1):13-20.
32. Withers GS, Greenough WT. Reach training selectively alters dendritic branching in subpopulations of layer II-III pyramids in rat motor-somatosensory forelimb cortex. Neuropsychologia. 1989;27(1):61-69.
33. Dobrossy MD, Dunnett SB. The influence of environment and experience on neural grafts. Nat Rev Neurosci. 2001;2(12):871-879.
34. Kami A, Meyer G, Rey-Hipolito C, et al. The acquisition of skilled motor performance: fast and slow experience-driven changes in primary motor cortex. Proc Natl Acad Sci USA. 1998;95(3):861-868.
35. Kleim JA, Barbay S, Nudo RJ. Functional reorganization of the rat motor cortex following motor skill learning. J Neurophysiol. 1998;80(6):3321-3325.
36. Nudo RJ, Wise BM, SiFuentes F, Milliken GW. Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct. Science. 1996;272(5269):1791-1794.
37. Pascual-Leone A, Nguyet D, Cohen LG, Brasil-Neto JP, Cammarota A, Hallett M. Modulation of muscle responses evoked by transcranial magnetic stimulation during the acquisition of new fine motor skills. J Neurophysiol. 1995;74(3):1037-1045.
38. Plautz EJ, Milliken GW, Nudo RJ. Effects of repetitive motor training on movement representations in adult squirrel monkeys: role of use versus learning. Neurobiol Learn Mem. 2000;74(1):27-55.
39. Castro-Alamancos MA, Borrel J. Functional recovery of forelimb response capacity after forelimb primary motor cortex damage in the rat is due to the reorganization of adjacent areas of cortex. Neuroscience. 1995;68(3):793-805.
40. Nudo RJ, Milliken GW, Jenkins WM, Merzenich MM. Use-dependent alterations of movement representations in primary motor cortex of adult squirrel monkeys. J Neurosci. 1996;16(2):785-807.
41. Nudo RJ, Plautz EJ, Frost SB. Role of adaptive plasticity in recovery of function after damage to motor cortex. Muscle Nerve. 2001;24(8):1000-1019.
42. Kolb B. Overview of cortical plasticity and recovery from brain injury. Phys Med Rehabil Clin N Am. 2003;14(1 suppl):S7-25, viii.
43. Penfield W Boldrey E. Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain. 1937;60:389-443.
44. Elbert T, Heim S, Rockstroh B. Neural plasticity and development. In: Nelson CA LM, ed. Handbook of Developmental Cognitive Neuroscience. Cambridge, MA: MIT Press; 2001:191-204.
45. Humphrey DR. Representation of movements and muscles within the primate precentral motor cortex: historical and current perspectives. Fed Proc. 1986;45(12):2687-2699.
46. Cohen LG, Gerloff C, Ikoma K, Hallett M. Plasticity of motor cortex elicited by training of synchronous movements of hand and shoulder. Soc Neurosci Abstr. 1995;21:517.
47. Cohen LG, Gerloff C, Faiz L, Uenishi N, Hallett M. Directional modulation of motor cortex plasticity induced by synchronicity of motor outputs in humans. Soc Neurosci Abstr. 1996;22:1452.
48. Crisostomo EA, Duncan PW, Propst M, Dawson DV, Davis JN. Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients. Ann Neurol. 1988;23(1):94-97.
49. Grafton ST, Mazziotta JC, Presty S, Friston KJ, Frackowiak RS, Phelps ME. Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET. J Neurosci. 1992;12(7):2542-2548.
50. Neumann-Haefelin T, Witte OW. Periinfarct and remote excitability changes after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab. 2000;20(1):45-52.
51. Hallett M. Plasticity of the human motor cortex and recovery from stroke. Brain Res Brain Res Rev. 2001;36(2-3):169-174.
52. Liepert J, Tegenthoff M, Malin JP. Changes of cortical motor area size during immobilization. Electroencephalogr Clin Neurophysiol. 1995;97(6):382-386.
53. Ottenbacher KJ, Jannell S. The results of clinical trials in stroke rehabilitation research. Arch Neurol. 1993;50(1):37-44.
54. Krech D, Rosenzweig MR, Bennett EL. Effects of environmental complexity and training on brain chemistry. J Comp Physiol Psychol. 1960;53:509-519.
55. Rosenzweig MR, Bennett EL. Psychobiology of plasticity: effects of training and experience on brain and behavior. Behav Brain Res. 1996;78(1):57-65.
56. Greenough WT, Volkmar FR. Pattern of dendritic branching in occipital cortex of rats reared in complex environments. Exp Neurol. 1973;40(2):491-504.
57. Mollgaard K, Diamond MC, Bennet EL, Rosenzweig MR, Lindner B. Quantitative synaptic changes with differential experience in rat brain. Int J Neurosci. 1971;2(3):113-127.
58. Greenough WT, Hwang HM, Gorman C. Evidence for active synapse formation or altered postsynaptic metabolism in visual cortex of rats reared in complex environments. Proc Natl Acad Sci USA. 1985;82(13):4549-4552.
59. Diamond MC, Ingham CA, Johnson RE, Bennett EL, Rosenzweig MR. Effects of environment on morphology of rat cerebral cortex and hippocampus. J Neurobiol. 1976;7(1):75-85.
60. Greenough WT, McDonald JW, Parnisari RM, Camel JE. Environmental conditions modulate degeneration and new dendrite growth in cerebellum of senescent rats. Brain Res. 1986;380(1):136-143.
61. Fuchs JL, Montemayor M, Greenough WT. Effect of environmental complexity on size of the superior colliculus. Behav Neural Biol. 1990;54(2):198-203.
62. Kolb B, Forgie M, Gibb R, Corny G, Rowntree S. Age, experience and the changing brain. Neurosci Biobehav Rev. 1998;22(2):143-159.
63. Schallen T, Leasure JL, Kolb B. Experience-associated structural events, subependymal cellular proliferative activity, and functional recovery after injury to the central nervous system. J Cereb Blood Flow Metab. 2000;20(11):1513-1528.
64. Diamond ME, Huang W, Ebner FF. Laminar comparison of somatosensory cortical plasticity. Science. 1994;265(5180):1885-1888.
65. Jones TA, Kleim JA, Greenough WT. Synaptogenesis and dendritic growth in the cortex opposite unilateral sensorimotor cortex damage in adult rats: a quantitative electron microscopic examination. Brain Res. 1996;733(1):142-148.
66. Kleim JA, Vij K, Ballard DH, Greenough WT. Learning-dependent synaptic modifications in the cerebellar cortex of the adult rat persist for at least four weeks. J Neurosci. 1997;17(2):717-721.
67. Klintsova AY, Greenough WT. Synaptic plasticity in cortical systems. Curr Opin Neurobiol. 1999;9(2):203-208.
68. Sirevaag AM, Greenough WT. Plasticity of GFAP-immunoreactive astrocyte size and number in visual cortex of rats reared in complex environments. Brain Res. 1991;540(1-2):273-278.
69. Jones TA, Greenough WT. Ultrastructural evidence for increased contact between astrocytes and synapses in rats reared in a complex environment. Neurobiol Learn Mem. 1996;65(1):48-56.
70. Donoghue JP, Sanes JN. Organization of adult motor cortex representation patterns following neonatal forelimb nerve injury in rats. J Neurosci. 1988;8(9):3221-3232.
71. Sanes JN, Suner S, Donoghue JP. Dynamic organization of primary motor cortex output to target muscles in adult rats. I. Long-term patterns of reorganization following motor or mixed peripheral nerve lesions. Exp Brain Res. 1990;79(3):479-491.
72. Jenkins WM, Merzenich MM, Ochs MT, Allard T, Guic-Robles E. Functional reorganization of primary somatosensory cortex in adult owl monkeys after behaviorally controlled tactile stimulation. J Neurophysiol. 1990;63(1):82-104.
73. Recanzone GH, Merzenich MM, Jenkins WM, Grajski KA, Dinse HR. Topographic reorganization of the hand representation in cortical area 3b owl monkeys trained in a frequency-discrimination task. J Neurophysiol. 1992;67(5):1031- 1056.
74. Ramachandran VS, Stewart M, Rogers-Ramachandran DC. Perceptual correlates of massive cortical reorganization. Neuroreport. 1992;3(7):583-586.
75. Aglioti S, Cortese F, Franchini C. Rapid sensory remapping in the adult human brain as inferred from phantom breast perception. Neuroreport. 1994;5(4):473-476.
76. Elbert T, Flor H, Birbaumer N, et al. Extensive reorganization of the somatosensory cortex in adult humans after nervous system injury. Neuroreport. 1994;5(18):2593-2597.
77. Halligan PW, Marshall JC, Wade DT. Sensory disorganization and perceptual plasticity after limb amputation: a follow-up study. Neuroreport. 1994;5(11):1341-1345.
78. Yang TT, Gallen CC, Ramachandran VS, Cobb S, Schwartz BJ, Bloom FE. Noninvasive detection of cerebral plasticity in adult human somatosensory cortex. Neuroreport. 1994;5(6):701-704.
79. Mogilner A, Grossman JA, Ribary U, et al. Somatosensory cortical plasticity in adult humans revealed by magnetoencephalography. Proc Natl Acad Sci USA. 1993;90(8):3593-3597.
80. Pascual-Leone A, Torres F. Plasticity of the sensorimotor cortex representation of the reading finger in Braille readers. Brain. 1993;116(pt 1):39-52.
81. Elbert T, Pantev C, Wienbruch C, Rockstroh B, Taub E. Increased cortical representation of the fingers of the left hand in string players. Science. 1995;270(5234):305-307.
82. Merzenich MM, Jenkins WM. Reorganization of cortical representations of the hand following alterations of skin inputs induced by nerve injury, skin island transfers, and experience. J Hand Ther. 1993;6(2):89-104.