Paneth type gastric cancer cells exhibit expression of human defensin-5 [6]

Histopathology

Volumn 47, Issue 3, 2005, Pages 330-331

  Inada, K I ^a   Mizoshita, T ^a   Tsukamoto, T ^a   Porter, E M ^b   Tatematsu, M ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; DEFENSIN; PROTEIN DEFENSIN 5; TRANSCRIPTION FACTOR CDX2; UNCLASSIFIED DRUG;

CANCER CELL; CELL DIFFERENTIATION; HISTOLOGY; HUMAN; INTESTINE METAPLASIA; LETTER; PANETH CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH CANCER;

ADENOCARCINOMA; CELL DIFFERENTIATION; DEFENSINS; HISTOCYTOCHEMISTRY; HOMEODOMAIN PROTEINS; HUMANS; PANETH CELLS; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 24144448023     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2005.02113.x     Document Type: Letter

References (6)

1. Porter EM, Liu L, Oren A, Anton PA, Ganz T. Localization of human intestinal defensin 5 in Paneth cell granules. Infect. Immun. 1997; 65; 2389-2395.
2. Inada K, Nakanishi H, Fujimitsu Y et al. Gastric and intestinal mixed and solely intestinal types of intestinal metaplasia in the human stomach. Pathol. Int. 1997; 47; 831-841.
3. Inada K, Tanaka H, Nakanishi H et al. Identification of Paneth cells in pyloric glands associated with gastric and intestinal mixed-type intestinal metaplasia of the human stomach. Virchows Arch. 2001; 439; 14-20.
4. Mizoshita T, Inada K, Tsukamoto T et al. Expression of the intestine-specific transcription factors, Cdx1 and Cdx2, correlates shift to an intestinal phenotype in gastric cancer cells. J. Cancer Res. Clin. Oncol. 2004; 130; 29-36.
5. Mizoshita T, Tsukamoto T, Nakanishi H et al. Expression of Cdx2 and the phenotype of advanced gastric cancers: relationship with prognosis. J. Cancer Res. Clin. Oncol. 2003; 129; 727-734.
6. Tatematsu M, Tsukamoto T, Inada K. Stem cells and gastric cancer-role of gastric and intestinal mixed intestinal metaplasia. Cancer Sci. 2003; 94; 135-141.