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Volumn 72, Issue 4, 2005, Pages 203-212

Gene expression analysis of human epidermal keratinocytes after N-acetyl L-cysteine treatment demonstrates cell cycle arrest and increased differentiation

Author keywords

Cell cycle; Gene expression; Keratinocytes; Microarray; N acetyl L cysteine; NHEK; Real time; RT PCR

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT;

EID: 24044509171     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000086790     Document Type: Article
Times cited : (18)

References (33)
  • 1
    • 0037068372 scopus 로고    scopus 로고
    • DNA methylation and chromatin - Unraveling the tangled web
    • Robertson KD: DNA methylation and chromatin - unraveling the tangled web. Oncogene 2002;21:5361-5379.
    • (2002) Oncogene , vol.21 , pp. 5361-5379
    • Robertson, K.D.1
  • 3
    • 1642512402 scopus 로고    scopus 로고
    • Tumour suppression: Putting on the brakes
    • Harris H: Tumour suppression: putting on the brakes. Nature 2004;427:201.
    • (2004) Nature , vol.427 , pp. 201
    • Harris, H.1
  • 6
    • 0035030407 scopus 로고    scopus 로고
    • cDNA microarray analysis of small plant tissue samples using a cDNA tag target amplification protocol
    • Hertzberg M, Sievertzon M, Aspeborg H, Nilsson P, Sandberg G, Lundeberg J: cDNA microarray analysis of small plant tissue samples using a cDNA tag target amplification protocol. Plant J 2001;25:585-591.
    • (2001) Plant J , vol.25 , pp. 585-591
    • Hertzberg, M.1    Sievertzon, M.2    Aspeborg, H.3    Nilsson, P.4    Sandberg, G.5    Lundeberg, J.6
  • 8
    • 0034869983 scopus 로고    scopus 로고
    • Normalization for cDNA microarray data
    • Bittner ML, Chen Y, Dorsel AN, Dougherty ER (eds): Bellingham, International Society for Optical Engineering
    • Yang Y, Dudoit S, Luu P, Speed T: Normalization for cDNA microarray data; in Bittner ML, Chen Y, Dorsel AN, Dougherty ER (eds): Microarrays: Optical Technologies and Informatics. Bellingham, International Society for Optical Engineering, 2001, pp 141-152.
    • (2001) Microarrays: Optical Technologies and Informatics , pp. 141-152
    • Yang, Y.1    Dudoit, S.2    Luu, P.3    Speed, T.4
  • 10
    • 0034929864 scopus 로고    scopus 로고
    • Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smoking-related end-points
    • De Flora S, Izzotti A, D'Agostini F, Balansky RM: Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smoking-related end-points. Carcinogenesis 2001;22:999-1013.
    • (2001) Carcinogenesis , vol.22 , pp. 999-1013
    • De Flora, S.1    Izzotti, A.2    D'Agostini, F.3    Balansky, R.M.4
  • 11
    • 1642462339 scopus 로고    scopus 로고
    • Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury
    • Hart AM, Terenghi G, Kellerth JO, Wiberg M: Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury. Neuroscience 2004;125:91-101.
    • (2004) Neuroscience , vol.125 , pp. 91-101
    • Hart, A.M.1    Terenghi, G.2    Kellerth, J.O.3    Wiberg, M.4
  • 13
    • 2942744826 scopus 로고    scopus 로고
    • N-acetylcysteine prevents lung inflammation after short-term inhalation exposure to concentrated ambient particles
    • Rhoden CR, Lawrence J, Godleski JJ, Gonzalez-Flecha B: N-acetylcysteine prevents lung inflammation after short-term inhalation exposure to concentrated ambient particles. Toxicol Sci 2004;79:296-303.
    • (2004) Toxicol Sci , vol.79 , pp. 296-303
    • Rhoden, C.R.1    Lawrence, J.2    Godleski, J.J.3    Gonzalez-Flecha, B.4
  • 14
    • 0032709575 scopus 로고    scopus 로고
    • N-acetylcysteine suppression of the proliferative index in the colon of patients with previous adenomatous colonic polyps
    • Estensen RD, Levy M, Klopp SJ, Galbraith AR, Mandel JS, Blomquist JA, Wattenberg LW: N-acetylcysteine suppression of the proliferative index in the colon of patients with previous adenomatous colonic polyps. Cancer Lett 1999;147:109-114.
    • (1999) Cancer Lett , vol.147 , pp. 109-114
    • Estensen, R.D.1    Levy, M.2    Klopp, S.J.3    Galbraith, A.R.4    Mandel, J.S.5    Blomquist, J.A.6    Wattenberg, L.W.7
  • 15
    • 0037453158 scopus 로고    scopus 로고
    • Gene expression profiling of Caco-2 BBe cells suggests a role for specific signaling pathways during intestinal differentiation
    • Fleet JC, Wang L, Vitek O, Craig BA, Edenberg HJ: Gene expression profiling of Caco-2 BBe cells suggests a role for specific signaling pathways during intestinal differentiation. Physiol Genomics 2003;13:57-68.
    • (2003) Physiol Genomics , vol.13 , pp. 57-68
    • Fleet, J.C.1    Wang, L.2    Vitek, O.3    Craig, B.A.4    Edenberg, H.J.5
  • 18
    • 0023986812 scopus 로고
    • A yeast gene required for the G1-to-S transition encodes a protein containing an A-kinase target site and GTPase domain
    • Kikuchi Y, Shimatake H, Kikuchi A: A yeast gene required for the G1-to-S transition encodes a protein containing an A-kinase target site and GTPase domain. EMBO J 1988;7:1175-1182.
    • (1988) EMBO J , vol.7 , pp. 1175-1182
    • Kikuchi, Y.1    Shimatake, H.2    Kikuchi, A.3
  • 19
    • 0024790320 scopus 로고
    • A human homologue of the yeast GST1 gene codes for a GTP-binding protein and is expressed in a proliferation-dependent manner in mammalian cells
    • Hoshino S, Miyazawa H, Enomoto T, Hanaoka F, Kikuchi Y, Kikuchi A, Ui M: A human homologue of the yeast GST1 gene codes for a GTP-binding protein and is expressed in a proliferation-dependent manner in mammalian cells. EMBO J 1989;8:3807-3814.
    • (1989) EMBO J , vol.8 , pp. 3807-3814
    • Hoshino, S.1    Miyazawa, H.2    Enomoto, T.3    Hanaoka, F.4    Kikuchi, Y.5    Kikuchi, A.6    Ui, M.7
  • 21
    • 0032521421 scopus 로고    scopus 로고
    • The Smad5 gene is involved in the intracellular signaling pathways that mediate the inhibitory effects of transforming growth factor-beta on human hematopoiesis
    • Bruno E, Horrigan SK, Van Den Berg D, Rozler E, Fitting PR, Moss ST, Westbrook C, Hoffman R: The Smad5 gene is involved in the intracellular signaling pathways that mediate the inhibitory effects of transforming growth factor-beta on human hematopoiesis. Blood 1998;91:1917-1923.
    • (1998) Blood , vol.91 , pp. 1917-1923
    • Bruno, E.1    Horrigan, S.K.2    Van Den Berg, D.3    Rozler, E.4    Fitting, P.R.5    Moss, S.T.6    Westbrook, C.7    Hoffman, R.8
  • 22
    • 4043147087 scopus 로고    scopus 로고
    • Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling
    • Rios I, Alvarez-Rodriguez R, Marti E, Pons S: Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling. Development 2004;131:3159-3168.
    • (2004) Development , vol.131 , pp. 3159-3168
    • Rios, I.1    Alvarez-Rodriguez, R.2    Marti, E.3    Pons, S.4
  • 23
    • 0037159280 scopus 로고    scopus 로고
    • Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells
    • Valdimarsdottir G, Goumans MJ, Rosendahl A, Brugman M, Itoh S, Lebrin F, Sideras P, ten Dijke P: Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells. Circulation 2002;106:2263-2270.
    • (2002) Circulation , vol.106 , pp. 2263-2270
    • Valdimarsdottir, G.1    Goumans, M.J.2    Rosendahl, A.3    Brugman, M.4    Itoh, S.5    Lebrin, F.6    Sideras, P.7    Ten Dijke, P.8
  • 24
    • 0035032914 scopus 로고    scopus 로고
    • Divergence and convergence of TGF-beta/BMP signaling
    • Miyazono K, Kusanagi K, Inoue H: Divergence and convergence of TGF-beta/BMP signaling. J Cell Physiol 2001;187:265-276.
    • (2001) J Cell Physiol , vol.187 , pp. 265-276
    • Miyazono, K.1    Kusanagi, K.2    Inoue, H.3
  • 25
    • 0038300810 scopus 로고    scopus 로고
    • Splice site and deletion mutations in keratin (KRT1 and KRT10) genes: Unusual phenotypic alterations in Scandinavian patients with epidermolytic hyperkeratosis
    • Virtanen M, Smith SK, Gedde-Dahl T Jr, Vahlquist A, Bowden PE: Splice site and deletion mutations in keratin (KRT1 and KRT10) genes: unusual phenotypic alterations in Scandinavian patients with epidermolytic hyperkeratosis. J Invest Dermatol 2003;121:1013-1020.
    • (2003) J Invest Dermatol , vol.121 , pp. 1013-1020
    • Virtanen, M.1    Smith, S.K.2    Gedde-Dahl Jr., T.3    Vahlquist, A.4    Bowden, P.E.5
  • 26
    • 0029932799 scopus 로고    scopus 로고
    • Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ('epidermal differentiation complex') on human chromosome 1q21
    • Mischke D, Korge BP, Marenholz I, Volz A, Ziegler A: Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ('epidermal differentiation complex') on human chromosome 1q21. J Invest Dermatol 1996;106:989-992.
    • (1996) J Invest Dermatol , vol.106 , pp. 989-992
    • Mischke, D.1    Korge, B.P.2    Marenholz, I.3    Volz, A.4    Ziegler, A.5
  • 29
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • Derynck R, Akhurst RJ, Balmain A: TGF-beta signaling in tumor suppression and cancer progression. Nat Genet 2001;29:117-129.
    • (2001) Nat Genet , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 30
    • 0034039438 scopus 로고    scopus 로고
    • Association of extracellular matrix proteins fibulin-1 and fibulin-2 with fibronectin in bone marrow stroma
    • Gu YC, Nilsson K, Eng H, Ekblom M: Association of extracellular matrix proteins fibulin-1 and fibulin-2 with fibronectin in bone marrow stroma. Br J Haematol 2000;109:305-313.
    • (2000) Br J Haematol , vol.109 , pp. 305-313
    • Gu, Y.C.1    Nilsson, K.2    Eng, H.3    Ekblom, M.4
  • 32
    • 0027361671 scopus 로고
    • Commitment to differentiation and expression of early differentiation markers in murine keratinocytes in vitro are regulated independently of extracellular calcium concentrations
    • Drozdoff V, Pledger WJ: Commitment to differentiation and expression of early differentiation markers in murine keratinocytes in vitro are regulated independently of extracellular calcium concentrations. J Cell Biol 1993;123:909-919.
    • (1993) J Cell Biol , vol.123 , pp. 909-919
    • Drozdoff, V.1    Pledger, W.J.2
  • 33
    • 0035968278 scopus 로고    scopus 로고
    • 2+ and BMP-6 signaling regulate E2F during epidermal keratinocyte differentiation
    • 2+ and BMP-6 signaling regulate E2F during epidermal keratinocyte differentiation. J Biol Chem 2001;276:23531-23538.
    • (2001) J Biol Chem , vol.276 , pp. 23531-23538
    • D'Souza, S.J.1    Pajak, A.2    Balazsi, K.3    Dagnino, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.