Enhanced c-Fos in periaqueductal grey GABAergic neurons during opioid withdrawal

NeuroReport

Volumn 16, Issue 12, 2005, Pages 1279-1283

  Chieng, Billy C H ^a   Hallberg, Catharina ^b   Nyberg, Fred J ^b   Christie, MacDonald J ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Aminobutyric acid; c Fos; Green fluorescent protein; Opioid withdrawal; Periaqueductal grey

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; GLUTAMATE DECARBOXYLASE; GREEN FLUORESCENT PROTEIN; MORPHINE; NALOXONE; OPIATE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG OVERDOSE; DRUG WITHDRAWAL; EXPERIMENTAL MODEL; GABAERGIC TRANSMISSION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOUSE; NONHUMAN; ONCOGENE C FOS; OPIATE ADDICTION; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ANIMALS; CELL COUNT; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION; GLUTAMATE DECARBOXYLASE; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MALE; MICE; MICE, TRANSGENIC; NARCOTICS; NEURONS; PERIAQUEDUCTAL GRAY; PROTO-ONCOGENE PROTEINS C-FOS; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 24044457030     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.wnr.0000175246.35837.5c     Document Type: Article

References (24)

1. Williams JT, Christie MJ, Manzoni O. Cellular and synaptic adaptations mediating opioid dependence. Physiol Rev 2001; 81:299-343.
2. Blasig J, Herz A, Reinhold K, Zieglgansberger S. Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats. Psychopharmacology 1973; 33:19-38.
3. Maldonado R, Stinus L, Gold LH, Koob GF. Role of different brain structures in the expression of the physical morphine withdrawal syndrome. J Pharmacol Exp Ther 1992; 261:669-677.
4. Bozarth MA. Physical dependence produced by central morphine infusions: an anatomical mapping study. Neurosci Biobehav Rev 1994; 18:373-383.
5. Chieng B, Keay KA, Christie MJ. Increased fos-like immunoreactivity in the periaqueductal gray of anaesthetised rats during opiate withdrawal. Neurosci Lett 1995; 183:79-82.
6. Bellchambers CE, Chieng B, Keay KA, Christie MJ. Swim-stress but not opioid withdrawal increases expression of c-fos immunoreactivity in rat periaqueductal gray neurons which project to the rostral ventromedial medulla. Neuroscience 1998; 83:517-524.
7. Chieng B, Christie MJ. Local opioid withdrawal in rat single periaqueductal gray neurons in vitro. J Neurosci 1996; 16:7128-7136.
8. Bagley EE, Gerke MB, Vaughan CW, Hack SP, Christie MJ. GABA transporter currents activated by protein kinase A excite midbrain neurons during opioid withdrawal. Neuron 2005; 45:433-445.
9. Reichling DB, Basbaum AI. Contribution of brainstem GABAergic circuitry to descending antinociceptive controls: I. GABA-immunoreactive projection neurons in the periaqueductal gray and nucleus raphe magnus. J Comp Neurol 1990; 302:370-377.
10. Kalyuzhny AE, Wessendorf MW. Relationship of mu- and delta-opioid receptors to GABAergic neurons in the central nervous system, including antinociceptive brainstem circuits. J Comp Neurol 1998; 392:528-547.
11. Sandner G, Dessort D, Schmitt P, Karli P. Distribution of GABA in the periaqueductal gray matter. Effects of medial hypothalamic lesions. Brain Res 1981; 224:279-290.
12. Ingram SL, Vaughan CW, Bagley EE, Connor M, Christie MJ. Enhanced opioid efficacy in opioid dependence is caused by an altered signal transduction pathway. J Neurosci 1998; 18:10269-10276.
13. Hack SP, Vaughan CW, Christie MJ. Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro. Neuropharmacology 2003; 45:575-584.
14. Oliva AA Jr, Jiang M, Lam T, Smith KL, Swann JW. Novel hippocampal interneuronal subtypes identified using transgenic mice that express green fluorescent protein in GABAergic interneurons. J Neurosci 2000; 20:3354-3368.
15. Franklin KB, Paxinos G. The mouse brain in stereotaxic coordinates. San Diego: Academic Press; 1997.
16. Yaksh TL, Yeung JC, Rudy TA. Systematic examination in the rat of brain sites sensitive to the direct application of morphine: observation of differential effects within the periaqueductal gray. Brain Res 1976; 114:83-103.
17. Barbaresi P, Gazzanelli G, Malatesta M. Gamma-aminobutyric acid transporters in the cat periaqueductal gray: a light and electron microscopic immunocytochemical study. J Comp Neurol 2001; 429:337-354.
18. Basbaum AI, Fields HL. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Ann Rev Neurosci 1984; 7:309-338.
19. Osborne PB, Vaughan CW, Wilson HI, Christie MJ. Opioid inhibition of rat periaqueductal grey neurones with identified projections to rostral ventromedial medulla in vitro. J Physiol 1996; 490:383-389.
20. Wang QP, Guan JL, Nakai Y. Immunoelectron microscopy of enkephalinergic innervation of GABAergic neurons in the periaqueductal gray. Brain Res 1994; 665:39-46.
21. Chieng B, Christie MJ. Inhibition by opioids acting on mu-receptors of GABAergic and glutamatergic postsynaptic potentials in single rat periaqueductal gray neurones in vitro. Br J Pharmacol 1994; 113:303-309.
22. Vaughan CW, Ingram SL, Connor MA, Christie MJ. How opioids inhibit GABA-mediated neurotransmission. Nature 1997; 390:611-614.
23. Swanson LW. Cerebral hemisphere regulation of motivated behavior. Brain Res 2000; 886:113-164.
24. Bandler R, Shipley MT. Columnar organization in the midbrain periaqueductal gray: modules for emotional expression? [Published erratum appears in Trends Neurosci 1994; 17:445] [see comments]. Trends Neurosci 1994; 17:379-389.