Marked differences between prone and supine sheep in effect of PEEP on perfusion distribution in zone II lung

Journal of Applied Physiology

Volumn 99, Issue 3, 2005, Pages 909-914

  Walther, Sten M ^a   Johansson, Mats J ^b   Flatebø, Torun ^c   Nicolaysen, Anne ^c   Nicolaysen, Gunnar ^c  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b LINKÖPING UNIVERSITY   (Sweden)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Gravity; Microspheres; Perfusion heterogeneity; Positive end expiratory pressure; Pulmonary circulation; Regional blood flow

Indexed keywords

MICROSPHERE;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; BODY POSTURE; COMPARATIVE STUDY; GRAVITY; ISOTOPE LABELING; LUNG ALVEOLUS; LUNG ARTERY PRESSURE; LUNG BLOOD FLOW; LUNG CAPACITY; LUNG PERFUSION; LUNG VASCULAR RESISTANCE; LUNG VOLUME; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RADIOACTIVITY; SHEEP; SUPINE POSITION; THORAX WALL; VENOUS PRESSURE;

EID: 24044456978     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.01388.2004     Document Type: Article

References (31)

1. Chornuk MA, Bernard SL, Burns JW, Glenny RW, Sheriff DD, Sinclair SE, Polissar NL, and Hlastala MP. Effects of inertial load and countermeasures on the distribution of pulmonary blood flow. J Appl Physiol 89: 445-457, 2000.
2. Glenny RW, Lamm WJ, Albert RK, and Robertson HT. Gravity is a minor determinant of pulmonary blood flow distribution. J Appl Physiol 71: 620-629, 1991.
3. Glenny RW, Lamm WJ, Bernard SL, An D, Chornuk M, Pool SL, Wagner WW, Hlastala MP, and Robertson HT. Selected contribution: Redistribution of pulmonary perfusion during weightlessness and increased gravity. J Appl Physiol 89: 1239-1248, 2000.
4. Glenny RW, Polissar L, and Robertson HT. Relative contribution of gravity to pulmonary perfusion heterogeneity. J Appl Physiol 71: 2449-2452, 1991.
5. Hakim TS, Lisbona R, and Dean GW. Gravity-independent inequality in pulmonary blood flow in humans. J Appl Physiol 63: 1114-1121, 1987.
6. Hakim TS, Lisbona R, and Dean GW. Gravity-nondependent distribution of pulmonary blood flow. J Appl Physiol 66: 1014-1015, 1989.
7. Hedenstierna G. Causes of gas exchange impairment during general anaesthesia. Eur J Anaesthesiol 5: 221-231, 1988.
8. Hedenstierna G, White FC, Mazzone R, and Wagner PD. Redistribution of pulmonary blood flow in the dog with PEEP ventilation. J Appl Physiol 46: 278-287, 1979.
9. Hedenstierna G, White FC, and Wagner PD. Spatial distribution of pulmonary blood flow in the dog with PEEP ventilation. J Appl Physiol 47: 938-946, 1979.
10. Hoffman EA. Effect of body orientation on regional lung expansion: a computed tomographic approach. J Appl Physiol 59: 468-480, 1985.
11. Howell JB, Permutt S, Proctor DF, and Riley RL. Effect of inflation of the lung on different parts of pulmonary vascular bed. J Appl Physiol 16: 71-76, 1961.
12. Hughes JM, Glazier JB, Maloney JE, and West JB. Effect of lung volume on the distribution of pulmonary blood flow in man. Respir Physiol 4: 58-72, 1968.
13. Iversen PO, Standa M, and Nicolaysen G. Marked regional heterogeneity in blood flow within a single skeletal muscle at rest and during exercise hyperaemia in the rabbit. Acta Physiol Scand 136: 17-28, 1989.
14. Kallas HJ, Domino KB, Glenny RW, Anderson EA, and Hlastala MP. Pulmonary blood flow redistribution with low levels of positive end-expiratory pressure. Anesthesiology 88: 1291-1299, 1998.
15. Koyama S, Lamm WJ, Hildebrandt J, and Albert RK. Flow characteristics of open vessels in zone 1 rabbit lungs. J Appl Physiol 66: 1817-1823, 1989.
16. Martynowicz MA, Walters BJ, and Hubmayr RD. Mechanisms of recruitment in oleic acid-injured lungs. J Appl Physiol 90: 1744-1753, 2001.
17. Melsom MN, Flatebo T, Kramer-Johansen J, Aulie A, Sjaastad OV, Iversen PO, and Nicolaysen G. Both gravity and non-gravity dependent factors determine regional blood flow within the goat lung. Acta Physiol Scand 153: 343-353, 1995.
18. Melsom MN, Kramer-Johansen J, Flatebo T, Muller C, and Nicolaysen G. Distribution of pulmonary ventilation and perfusion measured simultaneously in awake goats Acta Physiol Scand 159: 199-208, 1997.
19. [Corrigenda. Acta Physiol Scand 160: July 1997. p. 297.]
20. Musch G, Layfield JD, Harris RS, Melo MF, Winkler T, Callahan RJ, Fischman AJ, and Venegas JG. Topographical distribution of pulmonary perfusion and ventilation, assessed by PET in supine and prone humans. J Appl Physiol 93: 1841-1851, 2002.
21. Nicolaysen G, Shepard J, Onizuka M, Tanita T, Hattner RS, and Staub NC. No gravity-independent gradient of blood flow distribution in dog lung. J Appl Physiol 63: 540-545, 1987.
22. Nyren S, Mure M, Jacobsson H, Larsson SA, and Lindahl SG. Pulmonary perfusion is more uniform in the prone than in the supine position: scintigraphy in healthy humans. J Appl Physiol 86: 1135-1141, 1999.
23. Parker JC, Ardell JL, Hamm CR, Barman SA, and Coker PJ. Regional pulmonary blood flow during rest, tilt, and exercise in unanesthetized dogs. J Appl Physiol 78: 838-846, 1995.
24. Reed JH Jr and Wood EH. Effect of body position on vertical distribution of pulmonary blood flow. J Appl Physiol 28: 303-311, 1970.
25. Rehder K, Knopp TJ, and Sessler AD. Regional intrapulmonary gas distribution in awake and anesthetized-paralyzed prone man. J Appl Physiol 45: 528-535, 1978.
26. Richard JC, Decailliot F, Janier M, Annat G, and Guerin C. Effects of positive end-expiratory pressure and body position on pulmonary blood flow redistribution in mechanically ventilated normal pigs. Chest 122: 998-1005, 2002.
27. Rosenzweig DY, Hughes JM, and Glazier JB. Effects of transpulmonary and vascular pressures on pulmonary blood volume in isolated lung. J Appl Physiol 28: 553-560, 1970.
28. Walther SM, Domino KB, Glenny RW, and Hlastala MP. Positive end-expiratory pressure redistributes perfusion to dependent lung regions in supine but not in prone lambs. Crit Care Med 27: 37-45, 1999.
29. Walther SM, Domino KB, Glenny RW, and Hlastala MP. Pulmonary blood flow distribution in sheep: effects of anesthesia, mechanical ventilation, and change in posture. Anesthesiology 87: 335-342, 1997.
30. Walther SM, Domino KB, Glenny RW, Polissar NL, and Hlastala MP. Pulmonary blood flow distribution has a hilar-to-peripheral gradient in awake, prone sheep. J Appl Physiol 82: 678-685, 1997.
31. 2. J Appl Physiol 15: 405-410, 1960.