Physiology of a microgravity environment selected contribution: Redistribution of pulmonary perfusion during weightlessness and increased gravity

Journal of Applied Physiology

Volumn 89, Issue 3, 2000, Pages 1239-1248

  Glenny, Robb W ^a,d   Lamm, Wayne J E ^a   Bernard, Susan L ^a   An, Dowon ^a   Chornuk, Myron ^a   Pool, Sam L ^b   Wagner Jr , Wiltz W ^c   Hlastala, Michael P ^a   Robertson, H Thomas ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b NASA JOHNSON SPACE CENTER   (United States)

^c INDIANA UNIVERSITY   (United States)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Blood flow; Fluorescent microspheres; Microgravity; Prone; Supine

Indexed keywords

MICROSPHERE; FLUORESCENT DYE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD GAS ANALYSIS; BODY POSTURE; CENTRAL VENOUS PRESSURE; CONTROLLED STUDY; GRAVITY; HEART RATE; LUNG ARTERY PRESSURE; LUNG BLOOD FLOW; LUNG PERFUSION; MICROGRAVITY; NONHUMAN; PRIORITY JOURNAL; SPACE FLIGHT; SWINE; WEIGHTLESSNESS; ANIMAL; BIOLOGICAL MODEL; BLOOD VESSEL; FLIGHT EXPERIMENT; HISTOLOGY; LUNG CIRCULATION; LUNG GAS EXCHANGE; MANNED; NASA DISCIPLINE CARDIOPULMONARY; NON-NASA CENTER; PARABOLIC FLIGHT; PHYSIOLOGY; SHORT DURATION; STATISTICAL MODEL;

NASA DISCIPLINE CARDIOPULMONARY; NON-NASA CENTER;

FLIGHT EXPERIMENT; MANNED; PARABOLIC FLIGHT; SHORT DURATION;

ANIMALS; BLOOD VESSELS; FLUORESCENT DYES; GRAVITATION; HYPERGRAVITY; LINEAR MODELS; MICROSPHERES; MODELS, CARDIOVASCULAR; POSTURE; PULMONARY CIRCULATION; PULMONARY GAS EXCHANGE; SWINE; WEIGHTLESSNESS;

EID: 0034495288     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2000.89.3.1239     Document Type: Article

References (28)

1. Turnabout may be more than fair play
2. Ventilation: Total, alveolar, and dead space
3. Changes in lower limb volume in humans during parabolic flight
4. Differences in regional vascular conductances in isolated dog lungs
5. Transit time dispersion in the pulmonary arterial tree
6. Blood volume determination by the carbon monoxide method using a new delivery system: Accuracy in critically ill humans and precision in an animal model
7. Pulmonary circulation
8. Spatial correlation of regional pulmonary perfusion
9. Validation of fluorescent-labeled microspheres for measurement of regional organ perfusion
10. Hemodynamic effects of 15-μm diameter microspheres on the rat pulmonary circulation
11. Spatial pattern of pulmonary blood flow distribution is stable over days
12. Regional differences in the lung: A changing perspective on blood flow distribution
13. Spatial distribution of pulmonary blood flow in dogs in left decubitus position
14. Effect of lung volume on the distribution of pulmonary blood flow in man
15. Measuring the response time of pulmonary capillary recruitment to sudden flow changes
16. Both gravity and non-gravity dependent factors determine regional blood flow within the goat lung
17. Distribution of pulmonary ventilation and perfusion during short periods of weightlessness
18. No gravity-independent gradient of blood flow in the lung
19. Pulmonary gas exchange and its determinants during sustained microgravity on Spacelabs SLS-1 and SLS-2
20. Inhomogeneity of pulmonary perfusion during sustained microgravity on SLS-1
21. Effect of body position on vertical distribution of pulmonary blood flow
22. Effect of posture on pulmonary deadspace in man
23. The circulation of the fetus in utero. Methods for studying distribution of blood flow, cardiac output and organ blood flow
24. Regional differences in the lung
25. Distribution of blood flow and ventilation-perfusion in the lung, measured with radioactive C02
26. Distribution of blood flow in isolated lung: Relation to vascular and alveolar pressures