A simple spiroepoxide as methionine aminopeptidase-2 inhibitor: Synthetic problems and solutions

Tetrahedron Letters

Volumn 46, Issue 39, 2005, Pages 6691-6695

  Rodeschini, Vincent ^a   Van De Weghe, Pierre ^a   Tarnus, Céline ^a   Eustache, Jacques ^a  

^a UNIVERSITÉ DE HAUTE ALSACE   (France)

Author keywords

Fumagillin; Inhibition; MetAP 2; RCM

Indexed keywords

ENZYME INHIBITOR; EPOXIDE; HEPTANE; METHIONINE AMINOPEPTIDASE 2 INHIBITOR; METHIONINE DERIVATIVE; SPIRO COMPOUND; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL MODIFICATION; DRUG SYNTHESIS; EPOXIDATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION; RING CLOSING METATHESIS; STRUCTURE ACTIVITY RELATION;

EID: 24044449662     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.07.136     Document Type: Article

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