Synthesis of fluorescent phosphatidylinositols using a novel inositol H- phosphonate

Tetrahedron Letters

Volumn 39, Issue 19, 1998, Pages 2921-2924

  Leung, Lawrence W ^a   Vilchèze, Catherine ^a   Bittman, Robert ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INOSITOL PHOSPHATE; PHOSPHATIDYLINOSITOL;

ARTICLE; CELL MEMBRANE PERMEABILITY; COLUMN CHROMATOGRAPHY; DRUG SYNTHESIS; ENZYME ASSAY; ENZYME STABILITY; HAZARDOUS WASTE; NONHUMAN; PHOSPHOLIPID METABOLISM;

EID: 0032492945     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00418-3     Document Type: Article

References (17)

1. 1. (a) For a review, see: Bittman, R. in Phospholipids Handbook; Cevc, G., Ed.; Marcel Dekker: New York, 1993; pp 141-233.
2. (b) Filthuth, F.; Eibl, H. Chem. Phys. Lipids 1992, 60, 253-261.
3. 2. Stawinski, J.; Strömberg, R. Trends Org. Chem. 1993, 4, 31-67.
4. 3. (a) Vilchèze, C.; Bittman, R. J. Lipid Res. 1994, 35, 734-738.
5. (b) Byun, H-S.; Kumar, E. R.; Bittman, R. J. Org. Chem. 1994, 59, 2630-2633.
6. 4. Leung, L.W.; Bittman, R. Carbohydr. Res. 1997, 305, 179-187.
7. 5. Lindh, I.; Stawinski, J. J. Org. Chem. 1989, 54, 1338-1342;
8. (b) Garigapati, V. R.; Roberts, M. F. Tetrahedron Lett. 1993, 34, 769-772.
9. 6. Comfurius, P.; Zwaal, R. F. A. Biochim. Biophys. Acta 1977, 488, 36-42.
10. 8 to produce a phosphorothioate) into this molecule without altering the inositol 4-and 5-phosphate groups.
11. (b) Garegg, P.; Regberg, T.; Stawinski, J.; Strömberg, R. Nucleosides Nucleotides 1987, 6, 429-432.
12. 2/C in t-BuOH can be used: Kosikowski, A. P.; Tückmantel, W.; Powis, G. Angew. Chem. Intl. Ed., Engl. 1992, 31, 1379-1381.
13. 2/C in t-BuOH can be used: Kosikowski, A. P.; Tückmantel, W.; Powis, G. Angew. Chem. Intl. Ed., Engl. 1992, 31, 1379-1381.
14. 2/C in t-BuOH can be used: Kosikowski, A. P.; Tückmantel, W.; Powis, G. Angew. Chem. Intl. Ed., Engl. 1992, 31, 1379-1381.
15. 3Na: 929.3231. Found: 929.3198.
16. t 22 min; detection 280 nm.
17. 11. Low, M. G. In Methods in Inositide Research; Irvine, R. F., Ed.; Raven Press: New York, 1990, p 145-158.