A commercial mixture of the brominated flame retardant pentabrominated diphenyl ether (DE-71) induces respiratory burst in human neutrophil granulocytes in vitro

Toxicological Sciences

Volumn 87, Issue 1, 2005, Pages 57-65

  Reistad, Trine ^a   Mariussen, Espen ^b  

^a NORWEGIAN DEFENCE RESEARCH ESTABLISHMENT FFI   (Norway)

^b NORWEGIAN INSTITUTE FOR AIR RESEARCH   (Norway)

Author keywords

Brominated flame retardants (BFR); Calcium; Intracellular signaling pathways; Lucigenin; Pentabrominated diphenyl ethers (PeBDE); Reactive oxygen species (ROS)

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BDE 47; CALCIUM ION; CHELATING AGENT; DE 71; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FLAME RETARDANT; FORMYLMETHIONYLLEUCYLPHENYLALANINE; FURA 2; FURA 2 ACETOXYMETHYL ESTER; LUCIGENIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHOLIPASE C INHIBITOR; POLYBROMINATED DIPHENYL ETHER; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TYRPHOSTIN; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENZYME ACTIVATION; GRANULOCYTE; HUMAN; HUMAN CELL; NEUTROPHIL; RESPIRATORY BURST;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; CALCIUM; FLAME RETARDANTS; HUMANS; MALE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NADPH OXIDASE; NEUTROPHILS; PHENYL ETHERS; POLYBROMINATED BIPHENYLS; REACTIVE OXYGEN SPECIES; RESPIRATORY BURST; SIGNAL TRANSDUCTION;

EID: 24044448218     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi222     Document Type: Article

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