Involvement of protein kinase C activation in L-leucine-induced stimulation of protein synthesis in L6 myotubes

Cytotechnology

Volumn 43, Issue 1-3, 2003, Pages 97-103

  Yagasaki, Kazumi ^a   Morisaki, Naoko ^a   Kitahara, Yoshiro ^a   Miura, Atsuhito ^a   Funabiki, Ryuhei ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

L Leucine; L6 myotube; Protein kinase C inhibitor; Protein synthesis

Indexed keywords

2 OXOISOCAPROIC ACID; GLYCEROL DERIVATIVE; INDOMETACIN; LEUCINE; MEPACRINE; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; PROTEIN; PROTEIN KINASE C; TYROSINE;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; CELL FRACTIONATION; CONFERENCE PAPER; INHIBITION KINETICS; MYOTUBE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN SYNTHESIS; RAT; REGULATORY MECHANISM; STATISTICAL SIGNIFICANCE;

EID: 23944518003     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CYTO.0000039898.44839.90     Document Type: Conference Paper

References (23)

1. Ali A.R. and Evans P.J. 2001. Utilization of amino acids in growing kidney proximal tubule cell cultures. Cell. Biol. Int. 25: 451-465.
2. Anthony J.C., Yoshizawa F., Anthony T.G., Vary T.C., Jefferson L.S. and Kimball S.R. 2000. Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway. J. Nutr. 130: 2413-2419.
3. Antony J.C., Anthony T.G., Kimball S.R. and Jefferson L.S. 2001. Signaling pathways involved in translational control of protein synthesis in skeletal muscle by leucine. J. Nutr. 131: 856S-860S.
4. Braiman L., Alt A., Kuroki T., Ohba M., Bak A., Tennenbaum T. and Sampson S.R. 2001. Activation of protein kinase Cζ induces serine phosphorylation of VAMP2 in the GLUT4 compartment and increases glucose transport in skeletal muscle. Mol. Cell Biol. 21: 7852-7861.
5. Cooper D.R., Konda T.S., Standaert M.L., Davis J.S., Pollet R.J. and Farese R.V. 1987. Insulin increases membrane and cytosolic protein kinase C activity in BC3H-1 myocytes. J. Biol. Chem. 262: 3633-3639.
6. Fernandez L., Flores-Morales A., Lahuna O., Sliva D., Norstedt G., Haldosen L.A., Mode A. and Gustafsson J.Å. 1998. Desensitization of the growth hormone-include Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat 5)-signaling pathway requires protein synthesis and phospholipase C. Endocrinology 139: 1815-1824.
7. Ishizuka T., Kajita K., Miura A., Ishizawa M., Kanoh Y., Itaya S., Kimura M., Muto N., Mune T., Morita H. and Yasuda K. 1999. DHEA improves glucose uptake via activations of protein kinase C and phosphatidylinositol 3-kinase. Am. J. Physiol. 276: E196-E204.
8. Kimball S.R., Horetsky R.L. and Jefferson L.S. 1998. Implication of eIF2B rather than eIF4E in the regulation of global protein synthesis by amino acids in L6 myoblasts. J. Biol. Chem. 273: 30945-30953.
9. Koshihara Y., Neichi T., Murota S., Lao A., Fujimoto Y. and Tatsuno T. 1983. Selective inhibitor of 5-lipoxygenase by natural compounds isolated from Chinese plants, Artemisia rubripes Nakai. FEBS Lett. 158: 41-44.
10. Kramer I.M., van der Bend R.L., Tool A.T., van Blitterswijk W.J., Roos D. and Vehoeven A.L. 1989. 1-O-hexadecyl-2-O-methylglycerol, a novel inhibitor of protein kinase C, inhibits the respiratory burst in human neutrophils. J. Biol. Chem. 264: 5876-5884.
11. Lowry O.H., Rosebrough N.J., Farr A.L. and Randall R.J. 1951. Protein measurement with the Folin Phenol reagent. J. Biol. Chem. 193: 265-275.
12. Mortimore G.E., Pösö A.R., Kadowaki M. and Wert J.J. Jr. 1987. Multiphasic control of hepatic protein degradation by regulatory amino acids. J. Biol. Chem. 262: 16322-16327.
13. Patti M.-E., Brambilla E., Luzi L., Landaker E.J. and Kahn C.R. 1998. Bidirectional modulation of insulin action by amino acids. J. Clin. Invest. 101: 1519-1529.
14. Peyrollier K., Hajduch E., Blair A.S., Hyde R. and Hundal H.S. 2000. L-Leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of repamycin (mTOR) pathway in the L-Leucine-induced up-regulation of System A amino acid transport. Biochem. J. 350: 361-368.
15. Pösö A.R., Wert J.J. Jr. and Mortimore G.E. 1982. Multifunctional control by amino acids of deprivation-induced proteolysis in liver. J. Biol. Chem. 257: 12114-12120.
16. 2 are involved in the antiviral activity of human interferon-α. FEBS Lett. 249: 257-260.
17. 2α influence rates of protein turnover in skeletal and cardiac muscle. J. Biol. Chem. 257: 1632-1638.
18. Tischler M.E., Desautels M. and Goldberg A.L. 1982. Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle? J. Biol. Chem. 257: 1613-1621.
19. Yaffe D. 1968. Retention of differentiation potentialities during prolonged cultivation of myogenic cells. Proc. Natl. Acad. Sci. USA 61: 477-483.
20. Yagasaki K., Saito K., Yamaguchi M. and Funabiki R. 1991. Involvement of arachidonic acid metabolism in insulin-stimulated protein synthesis in cultured L6 myocytes. Agric. Biol. Chem. 55: 1449-1453.
21. Yagasaki K., Kida Y., Miura Y. and Funabiki R. 1994. Actions of branched chain amino acids on protein degradation in cultured muscle cells. In: Kobayashi T., Kitagawa Y. and Okumura K. (eds), Animal Cell Technology Basic & Applied Aspects, Vol. 6. Kluwer Academic Publishers, Dordrecht, pp. 279-285.
22. Yagasaki K., Morisaki-Tsuji N., Miura A. and Funabiki R. 2002a. Possible involvement of phospholipase C and protein kinase C in stimulatory actions of L-leucine and its keto acid, α-ketoisocaproic acid, on protein synthesis in RLC-16 hepatocytes. Cytotechnology 40: 151-154.
23. 2 and cyclooxygenase in stimulatory action of L-histidine on protein synthesis in L6 myotubes. Cytotechnology 40: 155-160.