메뉴 건너뛰기




Volumn 60, Issue 8, 2005, Pages 675-683

Influence of synthesis and processing conditions on the release behavior and stability of sol-gel derived silica xerogels embedded with bioactive compounds

Author keywords

Inorganic polymers; Polymer structure; Processing parameters; Silica gel; Sol gel; Sustained release; Synthesis

Indexed keywords

METHYLTRIETHOXYSILANE; POLYMER; SILANE DERIVATIVE; SILICON DIOXIDE; TETRAETHOXYSILANE; UNCLASSIFIED DRUG;

EID: 23944512831     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2005.05.007     Document Type: Article
Times cited : (14)

References (27)
  • 3
    • 0033991019 scopus 로고    scopus 로고
    • Silica xerogel as an implantable carrier for controlled drug delivery - Evaluation of drug distribution and tissue effects after implantation
    • P. Kortesuo, M. Ahola, S. Karlsson, I. Kangasniemi, A. Yli-Urpo, and J. Kiesvaara Silica xerogel as an implantable carrier for controlled drug delivery - evaluation of drug distribution and tissue effects after implantation Biomaterials 21 2000 193 198
    • (2000) Biomaterials , vol.21 , pp. 193-198
    • Kortesuo, P.1    Ahola, M.2    Karlsson, S.3    Kangasniemi, I.4    Yli-Urpo, A.5    Kiesvaara, J.6
  • 4
    • 0032475402 scopus 로고    scopus 로고
    • Encapsulation of biologicals within silicate, siloxane, and hybrid sol-gel polymers: An efficient and generic approach
    • I. Gill, and A. Ballesteros Encapsulation of biologicals within silicate, siloxane, and hybrid sol-gel polymers: an efficient and generic approach J. Am. Chem. Soc. 120 1998 8587 8598
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 8587-8598
    • Gill, I.1    Ballesteros, A.2
  • 5
    • 0034237721 scopus 로고    scopus 로고
    • Bioencapsulation within synthetic polymers (part 1): Sol-gel encapsulated biologicals
    • I. Gill, and A. Ballesteros Bioencapsulation within synthetic polymers (part 1): sol-gel encapsulated biologicals Trends Biotechnol. 18 2000 282 296
    • (2000) Trends Biotechnol. , vol.18 , pp. 282-296
    • Gill, I.1    Ballesteros, A.2
  • 6
    • 0034773128 scopus 로고    scopus 로고
    • Bio-doped nanocomposite polymers: Sol-gel bioencapsulates
    • I. Gill Bio-doped nanocomposite polymers: sol-gel bioencapsulates Chem. Mater. 13 2001 3404 3421
    • (2001) Chem. Mater. , vol.13 , pp. 3404-3421
    • Gill, I.1
  • 8
    • 0037067114 scopus 로고    scopus 로고
    • Properties and applications of proteins encapsulated within sol-gel derived materials
    • W. Jin, and J. Brennan properties and applications of proteins encapsulated within sol-gel derived materials Anal. Chim. Acta 461 2002 1 36
    • (2002) Anal. Chim. Acta , vol.461 , pp. 1-36
    • Jin, W.1    Brennan, J.2
  • 9
    • 0020658082 scopus 로고
    • The use of porous and surface modified silicas as drug delivery and stabilizing agents
    • K. Unger, H. Rupprecht, B. Valentin, and W. Kircher The use of porous and surface modified silicas as drug delivery and stabilizing agents Drug Dev. Ind. Pharm. 9 1983 69 91
    • (1983) Drug Dev. Ind. Pharm. , vol.9 , pp. 69-91
    • Unger, K.1    Rupprecht, H.2    Valentin, B.3    Kircher, W.4
  • 12
    • 0034630866 scopus 로고    scopus 로고
    • In vitro evaluation of sol-gel processed spray dried silica gel microspheres as carrier in controlled drug delivery
    • P. Kortesuo, M. Ahola, M. Kangas, I. Kangasniemi, A. Yli-Urpo, and J. Kiesvaara In vitro evaluation of sol-gel processed spray dried silica gel microspheres as carrier in controlled drug delivery Int. J. Pharm. 200 2000 223 229
    • (2000) Int. J. Pharm. , vol.200 , pp. 223-229
    • Kortesuo, P.1    Ahola, M.2    Kangas, M.3    Kangasniemi, I.4    Yli-Urpo, A.5    Kiesvaara, J.6
  • 14
    • 0035912877 scopus 로고    scopus 로고
    • In vitro release of dexmedetomidine from silica xerogel monoliths: Effect of sol-gel synthesis parameters
    • P. Kortesuo, M. Ahola, M. Kangas, A. Yli-Urpo, J. Kiesvaara, and M. Marvola In vitro release of dexmedetomidine from silica xerogel monoliths: effect of sol-gel synthesis parameters Int. J. Pharm. 221 2001 107 114
    • (2001) Int. J. Pharm. , vol.221 , pp. 107-114
    • Kortesuo, P.1    Ahola, M.2    Kangas, M.3    Yli-Urpo, A.4    Kiesvaara, J.5    Marvola, M.6
  • 15
    • 0034774615 scopus 로고    scopus 로고
    • Silica sol-gel for the controlled release of antibiotics. I. Synthesis, characterization, and in vitro release
    • S. Radin, P. Ducheyne, T. Kamplain, and B.H. Tan Silica sol-gel for the controlled release of antibiotics. I. Synthesis, characterization, and in vitro release J. Biomed. Mater. Res. 57 2001 313 320
    • (2001) J. Biomed. Mater. Res. , vol.57 , pp. 313-320
    • Radin, S.1    Ducheyne, P.2    Kamplain, T.3    Tan, B.H.4
  • 16
    • 0035814246 scopus 로고    scopus 로고
    • Silica sol-gel for the controlled release of antibiotics. II. the effect of synthesis parameters on the in vitro release kinetics of vanomycin
    • W. Aughenbaugh, S. Radin, and P. Ducheyne Silica sol-gel for the controlled release of antibiotics. II. The effect of synthesis parameters on the in vitro release kinetics of vanomycin J. Biomed. Mater. Res. 57 2001 321 326
    • (2001) J. Biomed. Mater. Res. , vol.57 , pp. 321-326
    • Aughenbaugh, W.1    Radin, S.2    Ducheyne, P.3
  • 19
    • 0032314032 scopus 로고    scopus 로고
    • Sol-gel carrier systems for controlled drug delivery
    • H. Bottcher, P. Slowik, and W. Suss Sol-gel carrier systems for controlled drug delivery J. Sol-Gel Sci. Technol. 13 1998 277 281
    • (1998) J. Sol-Gel Sci. Technol. , vol.13 , pp. 277-281
    • Bottcher, H.1    Slowik, P.2    Suss, W.3
  • 20
    • 0003409382 scopus 로고
    • K. Grasshoff K. Kremling M. Ehrhardt Wiley-VCH Weinheim
    • F. Koroleff K. Grasshoff K. Kremling M. Ehrhardt Methods of Seawater Analysis 1983 Wiley-VCH Weinheim 174 183
    • (1983) Methods of Seawater Analysis , pp. 174-183
    • Koroleff, F.1
  • 21
    • 0344893332 scopus 로고
    • Mechanism of sustained-action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
    • T. Higuchi Mechanism of sustained-action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices J. Pharm. Sci. 52 1963 1145 1149
    • (1963) J. Pharm. Sci. , vol.52 , pp. 1145-1149
    • Higuchi, T.1
  • 23
    • 12444272525 scopus 로고
    • Adsorption of gases in multimolecular layers
    • S. Brunauer, P.H. Emmet, and E. Teller Adsorption of gases in multimolecular layers J. Am. Chem. Soc. 60 1938 309 319
    • (1938) J. Am. Chem. Soc. , vol.60 , pp. 309-319
    • Brunauer, S.1    Emmet, P.H.2    Teller, E.3
  • 26
    • 0032668320 scopus 로고    scopus 로고
    • Influence of sol-gel synthesis parameters on the microstructure of particulate silica xerogels
    • D.L. Meixner, and P.N. Dyer Influence of sol-gel synthesis parameters on the microstructure of particulate silica xerogels J. Sol-Gel Sci. Technol. 14 1999 223 232
    • (1999) J. Sol-Gel Sci. Technol. , vol.14 , pp. 223-232
    • Meixner, D.L.1    Dyer, P.N.2
  • 27
    • 3543100660 scopus 로고
    • Effects of dimethyldiethoxysilane addition on tetraetylorthosilicate sol-gel process
    • S.K. Mah, and I.J. Chung Effects of dimethyldiethoxysilane addition on tetraetylorthosilicate sol-gel process J. Non-Cryst. Solids 183 1995 252 259
    • (1995) J. Non-Cryst. Solids , vol.183 , pp. 252-259
    • Mah, S.K.1    Chung, I.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.