Synthesis of aryl-1,2,4-triazine-3,5-diones as antagonists of the gonadotropin-releasing hormone receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 19, 2005, Pages 4363-4366

  Pontillo, Joseph ^a   Guo, Zhiqiang ^a   Wu, Dongpei ^a   Struthers, R Scott ^a   Chen, Chen ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

Antagonist; Azauracil; GnRH; Synthesis; Triazinedione

Indexed keywords

1,2,4 TRIAZINE DERIVATIVE; GONADORELIN ANTAGONIST;

ARTICLE; COMPREHENSION; DRUG EFFICACY; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

HUMANS; KETONES; PROTEIN BINDING; RECEPTORS, LHRH; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZINES;

EID: 23944498620     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.06.057     Document Type: Article

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