Uracils as potent antagonists of the human gonadotropin-releasing hormone receptor without atropisomers

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 10, 2005, Pages 2519-2522

  Guo, Zhiqiang ^a   Chen, Yongsheng ^a   Huang, Charles Q ^a   Gross, Timothy D ^a   Pontillo, Joseph ^a   Rowbottom, Martin W ^a   Saunders, John ^a   Struthers, Scott ^a   Tucci, Fabio C ^a   Xie, Qiu ^a   Wade, Warren ^a   Zhu, Yun Fei ^a   Wu, Dongpei ^a   Chen, Chen ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

antagonist; Atropisomer; GnRH; Uracil

Indexed keywords

GONADORELIN RECEPTOR; RECEPTOR BLOCKING AGENT; URACIL;

ARTICLE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMER; STRUCTURE ACTIVITY RELATION;

EID: 20944443758     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.057     Document Type: Article

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