ACTH, α-MSH, and control of cortisol release: Cloning, sequencing, and functional expression of the melanocortin-2 and melanocortin-5 receptor in Cyprinus carpio

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 289, Issue 3 58-3, 2005, Pages

  Metz, Juriaan R ^a   Geven, Edwin J W ^a   Van Den Burg, Erwin H ^a   Flik, Gert ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Receptor; Stress

Indexed keywords

ALPHA INTERMEDIN; COMPLEMENTARY DNA; HYDROCORTISONE; MELANOCORTIN 2 RECEPTOR; MELANOCORTIN 5 RECEPTOR; MESSENGER RNA; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARP; ENZYME PHOSPHORYLATION; FISH; HORMONE BLOOD LEVEL; HORMONE RELEASE; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHYLOGENY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; REAL TIME POLYMERASE CHAIN REACTION; STRESS; UNINDEXED SEQUENCE;

ADRENOCORTICOTROPIC HORMONE; ALPHA-MSH; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARPS; CLONING, MOLECULAR; HYDROCORTISONE; KIDNEY; MOLECULAR SEQUENCE DATA; PHYLOGENY; RECEPTOR, MELANOCORTIN, TYPE 2; RECEPTORS, CORTICOTROPIN; RESTRAINT, PHYSICAL; STRESS; TISSUE DISTRIBUTION;

EID: 23944493797     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00826.2004     Document Type: Article

References (70)

1. Arenas RJ, Mancera JM, Munoz JL, Wendelaar Bonga SE, and Flik G. The stress response of the gilthead sea bream (Sparus aurata L.) to air exposure and confinement. J Endocrinol 163: 149-157, 1999.
2. Arends RJ, Van der Gaag R, Martens GJM, Wendelaar Bonga SE, and Flik G. Differential expression of two pro-opiomelanocortin mRNAs during temperature stress in the common carp (Cyprinus carpio L.). J Endocrinol 159: 85-91, 1998.
3. Arends RJ, Vermeer H, Martens GJM, Leunissen JAM, Wendelaar Bonga SE, and Flik G. Cloning and expression of two proopiomelanocortin mRNAs in the common carp (Cyprinus carpio L.). Mol Cell Endocrinol 143: 23-31, 1998.
4. Balm PHM, Hovens ML, and Wendelaar Bonga SE. Endorphin and MSH in concert form the corticotropic principle released by tilapia (Oreochromis mossambicus; Teleoslei) melan otropes. Peptides 16: 463-469, 1995.
5. Balm PHM and Pottinger TG. Corticotrope and melanotrope POMC-derived peptides in relation to interrenal function during stress in rainbow trout (Oncorhynchus mykiss). Gen Comp Endocrinol 98: 279-288, 1995.
6. Banks WA and Kastin AJ. Permeability of the blood-brain barrier to melanocortins. Peptides 16: 1157-1161, 1995.
7. Bongers ABJ, Ben-Ayed MZ, Zandieh Doulabi B, Komen J, and Richter CJJ. Origin of variation in isogenic, gynogenetic, and androgenetic strains of common carp, Cyprinus carpio. J Exp Zool 277: 72-79, 1997.
8. Brennan MB, Costa JL, Forbes S, Reed P, Bui S, and Hochgeschwender U. Alpha-melanocyte-stimulating hormone is a peripheral, integrative regulator of glucose and fat metabolism. Ann NY Acad Sci 994: 282-287, 2003.
9. Cerda-Reverter JM, Ling MK, Schiöth HB, and Peter RE. Molecular cloning, characterization and brain mapping of the melanocortin 5 receptor in the goldfish. J Neurochem 87: 1354-1367, 2003.
10. Cerda-Reverter JM and Peter RE. Endogenous melanocortin antagonist in fish: structure, brain mapping, and regulation by fasting of the goldfish agouti-related protein gene. Endocrinology 144: 4552-4561, 2003.
11. Cerda-Reverter JM, Ringholm A, Schioth HB, and Peter RE. Molecular cloning, pharmacological characterization, and brain mapping of the melanocortin 4 receptor in the goldfish: involvement in the control of food intake. Endocrinology 144: 2336-2349, 2003.
12. Cerda-Reverter JM, Schioth HB, and Peter RE. The central melanocortin system regulates food intake in goldfish. Regul Pept 115: 101-113, 2003.
13. Chen W, Kelly MA, Opitz-Araya X, Thomas RE, Low MJ, and Cone RD. Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides. Cell 91: 789-798, 1997.
14. Chester Jones I and Mosley W. The interrenal gland in fishes. Part I. Structure. In: General, Comparative and Clinical Endocrinology of the Adrenal Cortex, edited by Chester Jones I, and Henderson IW. San Diego, CA: Academic, p. 395-472, 1980.
15. Chhajlani V. Distribution of cDNA for melanocortin receptor subtypes in human tissues. Biochem Mol Biol Int 38: 73-80, 1996.
16. Chhajlani V, Muceniece R, and Wikberg JES. Molecular cloning of a novel human melanocortin receptor. Biochem Biophys Res Commun 195: 866-873, 1993.
17. Chhajlani V and Wikberg JES. Molecular cloning of the human melanocyte-stimulating hormone receptor cDNA. FEBS Lett 309: 417-420, 1992.
18. Colombe L, Fostier A, Bury N, Pakdel F, and Guiguen Y. A mineralocorticoid-like receptor in the rainbow trout, Oncorhynchus mykiss: cloning and characterization of its steroid binding domain. Steroids 65: 319-328, 2000.
19. Cone RD, Lu D, Koppula S, Vage DI, Klungland H, Boston B, Chen W, Orth DN, Pouton C, and Kesterson RA. The melanocortin receptors: agonists, antagonists and the hormonal control of pigmentation. Recent Prog Horm Res 51: 287-317, 1996.
20. Dohlman HG, Thorner J, Caron MG, and Lefkowitz RJ. Model systems for the study of seven-transmembrane-segmem receptors. Annu Rev Biochem 60: 653-688, 1991.
21. Ducouret B, Tujague M, Ashraf J, Mouchel N, Servel N, Valotaire Y, and Thompson EB. Cloning of a teleost fish glucoconicoid receptor shows that it contains a deoxyribonucleic acid-binding domain different from that of mammals. Endocrinology 136: 3774-3783, 1995.
22. Gallo VP and Civinini A. Survey of the adrenal homolog in teleosts. Int Rev Cytol 230: 89-187, 2003.
23. Gantz I and Fong TM. The melanocortin system. Am J Physiol Endocrinol Metab 284: E468-E474, 2003.
24. Gantz I, Konda Y, Tashiro T, Shimoto Y, Miwa H, Munzert G, Watson S, Delvalle J, and Yamada T. Molecular cloning of a novel melanocortin receptor. J Biol Chem 268: 8246-8250, 1993.
25. Gilmour KM. Mineralocorticoid receptors and hormones: fishing for answers. Endocrinology 146: 44-46, 2005.
26. Griffon N, Mignon V, Facchinetti P, Diaz J, Schwartz JC, and Sokoloff P. Molecular cloning and characterization of the rat fifth melanocortin receptor. Biochem Biophys Res Commun 200: 1007-1014, 1994.
27. Haitina T, Klovins J, Andersson J, Fredriksson R, Lagerstrom MC, Larhammar D, Larson ET, and Schiöth HB. Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes. Biochem J 380: 475-486, 2004.
28. Huising MO, Metz JR, van Schooten C, Taverne-Thiele AJ, Hermsen T, Verburg-van Kemenade BML, and Flik G. Structural characterization of a cyprinid (Cyprinus carpio L.) CRH, CRH-BP and CRH-R1, and the role of these proteins in the acute stress response. J Mol Endocrinol 32: 627-648, 2004.
29. Kalra SP, Dube MG, Pu S, Xu B, Horvarth TL, and Kalra PS. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20: 68-100, 1999.
30. Kapas S, Orford CD, Barker S, Vinson GP, and Hinson JP. Studies on the intracellular mechanism of action of alpha-melanocyte-stimulating hormone on rat adrenal zona glomerulosa. J Mol Endocrinol 9: 47-54, 1992.
31. Kitahara N, Nishizawa T, Iida K, Okazaka H, Andoh T, and Soma GI. Absence of a γ-melanocyte-stimulating hormone sequence in proopiomelanocortin mRNA of chum salmon Oncorhynchus keta. Comp Biochem Physiol 91B: 365-370, 1988.
32. Klovins J, Haitina T, Fridmanis D, Kilianova Z, Kapa I, Fredriksson R, Gallo-Payet N, and Schiöth HB. The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs. Mol Biol Evol 21: 563-579, 2004.
33. Kumar S, Tamura K, Jakobsen IB, and Nei M. MEGA2: molecular evolutionary genetics analysis software. Bioinformatics 17: 1244-1245, 2001.
34. Labbé O, Desarnaud F, Eggerickx D, Vassart G, and Parmentier M. Molecular cloning of a mouse melanocortin-5 receptor gene widely expressed in peripheral tissues. Biochemistry 33: 4543-4549, 1994.
35. Lamers AE, Flik G, Atsma W, and Wendelaar Bonga SE. A role for di-acetyl alpha-melanocyte-stimulating hormone in the control of cortisol release in the teleost Oreochromis mossambicus. J Endocrinol 135: 285-292, 1992.
36. Lamers AE, Flik G, and Wendelaar Bonga SE. A specific role for TRH in release of diacetyl alpha-MSH in tilapia stressed by acid water. Am J Physiol Regul Integr Comp Physiol 267: R1302-R1308, 1994.
37. Larhammar D and Risinger C. Molecular genetic aspects of tetraploidy in the common carp Cyprinus carpio. Mol Phylogenet Evol 3: 59-68, 1994.
38. Liakos P, Chambaz EM, Feige JJ, and Defaye G. Expression and regulation of melanocortin receptor-5 (MC5-R) in the bovine adrenal cortex. Mol Cell Endocrinol 159: 99-107, 2000.
39. Lipton JM, Ceriani G, Macaluso A, McCoy D, Carnes K, Biltz J, and Catania A. Antiinflammatory effects of the neuropeptide alpha-MSH in acute, chronic, and systemic inflammation. Ann NY Acad Sci 741: 137-148, 1994.
40. Logan DW, Bryson-Richardson RJ, Pagan KE, Taylor MS, Currie PD, and Jackson IJ. The structure and evolution of the melanocortin and MCH receptors in fish. Genomics 81: 184-191, 2003.
41. Lu XY, Barsh GS, Akil H, and Watson SJ. Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses. J Neurosci 23: 7863-7872, 2003.
42. Luger TA, Scholzen TE, Brzoska T, and Bohm M. New insights into the functions of α-MSH and related peptides in the immune system. Ann NY Acad Sci 994: 133-140, 2003.
43. Marshall RD. Glycoproteins. Annu Rev Biochem 41: 673-702, 1972.
44. McEwen BS and Wingfield JC. The concept of allostasis in biology and biomedicine. Horm Behav 43: 2-15, 2003.
45. Metz JR, Huising MO, Taverne-Thiele AJ, Wendelaar Bonga SE, and Flik G. Localization, expression, and control of adrenocorticotropic hormone in the brain and pituitary gland of the common carp (Cyprinus carpio L.). J Endocrinol 182: 23-31, 2004.
46. Mosconi G, Gallinelli A, Polzonetti-Magni AM, and Facchinetti F. Acetyl salmon endorphin-like and interrenal stress response in male gilthead sea bream, Sparus aurata. Neuroendocrinology 68: 129-134, 1998.
47. Mountjoy KG, Mortud MT, Low MJ, Simerly RB, and Cone RD. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Mol Endocrinol 8: 1298-1308, 1994.
48. Mountjoy KG, Robbins LS, Mortud MT, and Cone RD. The cloning of a family of genes that encode the melanocortin receptors. Science 257: 1248-1251, 1992.
49. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45, 2001.
50. Pignatelli D, Maia M, Castro AR, da Conceicao Magalhaes M, Vivier J, and Defaye G. Chronic stress effects on the rat adrenal cortex. Endocr Res 26: 537-544, 2000.
51. Ringholm A, Fredriksson R, Poliakova N, Van YL, Postlethwait JH, Larhammar D, and Schiöth HB. One melanocortin-4 and two melanocortin-5 receptors from zebrafish show remarkable conservation in structure and pharmacology. J Neurochem 82: 6-18, 2002.
52. Rotllant J, Balm PHM, Perez-Sanchez J, Wendelaar Bonga SE, and Tort L. Pituitary and interrenal function in gilthead sea bream (Sparus aurata L., Teleostei) after handling and confinement stress. Gen Comp Endocrinol 121: 333-342, 2001.
53. Saitou N and Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4: 406-425, 1987.
54. Salbert G, Chauveau I, Bonnec G, Valotaire Y, and Jego P. One of the two trout proopiomelanocortin messenger RNAs potentially encodes new peptides. Mol Endocrinol 6: 1605-1613, 1992.
55. Sanger F, Nicklen S, and Coulsen AR. DNA sequencing with chain termination inhibitors. Proc Natl Acad Sci USA 74: 5463-5467, 1977.
56. Schiöth HB, Chhajlani V, Muceniece R, Klusa V, and Wikberg JES. Major pharmacological distinction of the ACTH receptor from other melanocortin receptors. Life Sci 59: 797-801, 1996.
57. Schiöth HB, Muceniece R, Larsson M, and Wikberg JE. Characterization of melanocortin receptor subtypes by radioligand binding analysis. Eur J Pharmacol 288: 311-317, 1995.
58. Schiöth HB and Watanobe H. Melanocortins and reproduction. Brain Res Rev 38: 340-350, 2002.
59. Sloman KA, Desforges PR, and Gilmour KM. Evidence for a mineralocorticoid-like receptor linked to branchial chloride cell proliferation in freshwater rainbow trout. J Exp Biol 204: 3953-3961, 2001.
60. Strand FL. New vistas for melanocortins. Finally, an explanation for their pleiotropic functions. Ann NY Acad Sci 897: 1-16, 1999.
61. Sumpter JP, Dye HM, and Benfey TJ. The effects of stress on plasma ACTH, alpha-MSH, and cortisol levels in salmonid fishes. Gen Comp Endocrinol 62: 377-385, 1986.
62. Tran TN, Fryer JN, Bennett HP, Tonon MC, and Vaudry H. TRH stimulates the release of POMC-derived peptides from goldfish melanotropes. Peptides 10: 835-841, 1989.
63. Uyeno T and Smith GR. Tetraploid origin of the karyotype of catostomid fishes. Science 175: 644-646, 1972.
64. Van den Burg EH, Metz JR, Arends RJ, Devreese B, Vandenberghe I, Van Beeumen J, Wendelaar Bonga SE, and Flik G. Identification of β-endorphins in the pituitary gland and blood plasma of the common carp (Cyprinus carpio L.). J Endocrinol 169: 271-280, 2001.
65. Van den Burg EH, Metz JR, Ross HA, Darras VM, Wendelaar Bonga SE, and Flik G. Temperature-induced changes in thyrotropin-releasing hormone sensitivity in carp melanotropes. Neuroendocrinology 77: 15-23, 2003.
66. Van den Burg EH, Metz JR, Spanings FAT, Wendelaar Bonga SE, and Flik G. Plasma α-MSH and acetylated β-endorphin levels following stress vary according to CRH sensitivity of the pituitary melanotropes in common carp, Cyprinus carpio. Gen Comp Endocrinol 140: 210-221, 2005.
67. Van der Kraan M, Adan RAH, Entwistle ML, Gispen WH, Burbach JPH, and Tatro JB. Expression of melanocortin-5 receptor in secretory epithelia supports a functional role in exocrine and endocrine glands. Endocrinology 139: 2348-2355, 1998.
68. Vinson G, Whitehouse B, and Hinson J. The Adrenal Cortex. Englewood Cliffs, NJ: Prentice Hall, 1992.
69. Wendelaar Bonga SE. The stress response in fish. Physiol Rev 77: 591-625, 1997.
70. Woodget JR, Gould KL, and Hunter T. Substrate specificity of protein kinase C. Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements. Eur J Biochem 161: 177-184, 1986.