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Volumn 54, Issue 10, 2005, Pages 944-952

CTLA-4 blockade augments human T lymphocyte-mediated suppression of lung tumor xenografts in SCID mice

Author keywords

Human CTLA 4; Lymphocytes; SCID Mice; Xenografts

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; HYBRID PROTEIN; IMMUNOGLOBULIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 10A8; MONOCLONAL ANTIBODY P2; UNCLASSIFIED DRUG;

EID: 23944490393     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-005-0668-3     Document Type: Article
Times cited : (20)

References (35)
  • 1
    • 0029924107 scopus 로고    scopus 로고
    • Human tumor antigens recognized by T lymphocytes
    • Boon T, van der Bruggen P (1996) Human tumor antigens recognized by T lymphocytes. J Exp Med 183:725-729
    • (1996) J Exp Med , vol.183 , pp. 725-729
    • Boon, T.1    Van Der Bruggen, P.2
  • 2
    • 0033103021 scopus 로고    scopus 로고
    • A new era for cancer immunotherapy based on the genes that encode cancer antigens
    • Rosenberg SA (1999) A new era for cancer immunotherapy based on the genes that encode cancer antigens. Immunity 10:281-287
    • (1999) Immunity , vol.10 , pp. 281-287
    • Rosenberg, S.A.1
  • 3
    • 0034027829 scopus 로고    scopus 로고
    • CD4+ T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection
    • Cohen PA, Peng L, Plautz GE, et al. (2000) CD4+ T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection. Critical Reviews in Immunology 20:17-56
    • (2000) Critical Reviews in Immunology , vol.20 , pp. 17-56
    • Cohen, P.A.1    Peng, L.2    Plautz, G.E.3
  • 4
    • 0033991158 scopus 로고    scopus 로고
    • Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
    • Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S (2000) Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv Immunol 74:181-273
    • (2000) Adv Immunol , vol.74 , pp. 181-273
    • Marincola, F.M.1    Jaffee, E.M.2    Hicklin, D.J.3    Ferrone, S.4
  • 5
    • 0042470540 scopus 로고    scopus 로고
    • Does the immune system see tumors as foreign or self?
    • Pardoll D (2003) Does the immune system see tumors as foreign or self? Annu Rev Immunol 21:807-839
    • (2003) Annu Rev Immunol , vol.21 , pp. 807-839
    • Pardoll, D.1
  • 6
    • 0036136256 scopus 로고    scopus 로고
    • Intensity of the vaccine-elicited immune response determines tumor clearance
    • Perez-Diaz A, Spiess PJ, Restifo NP, et al. (2002) Intensity of the vaccine-elicited immune response determines tumor clearance. J Immunol 168:338-347
    • (2002) J Immunol , vol.168 , pp. 338-347
    • Perez-Diaz, A.1    Spiess, P.J.2    Restifo, N.P.3
  • 8
    • 0024327899 scopus 로고
    • Clonal expansion versus functional clonal inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy
    • Mueller DL, Jenkins MK, Schwartz RH (1989) Clonal expansion versus functional clonal inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. Annu Rev Immunol 7:445-480
    • (1989) Annu Rev Immunol , vol.7 , pp. 445-480
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 10
    • 0023270567 scopus 로고
    • A new member of the immunoglobulin superfamily- CTLA-4
    • Brunet JF, Denizot F, Luciani MF, et al (1987) A new member of the immunoglobulin superfamily- CTLA-4. Nature 328:267-270
    • (1987) Nature , vol.328 , pp. 267-270
    • Brunet, J.F.1    Denizot, F.2    Luciani, M.F.3
  • 11
    • 0025830902 scopus 로고
    • CTLA-4 is a second receptor for the B-cell activation antigen B7
    • Linsley PS, Brady W, Urnes M, et al. (1991) CTLA-4 is a second receptor for the B-cell activation antigen B7. J Exp Med 174:561-569
    • (1991) J Exp Med , vol.174 , pp. 561-569
    • Linsley, P.S.1    Brady, W.2    Urnes, M.3
  • 12
    • 0028675006 scopus 로고
    • Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
    • Linsley PS, Greene JL, Brady W, et al (1994) Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors. Immunity 1:793-801
    • (1994) Immunity , vol.1 , pp. 793-801
    • Linsley, P.S.1    Greene, J.L.2    Brady, W.3
  • 13
    • 0031054242 scopus 로고    scopus 로고
    • CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics
    • van der Merwe PA, Bodian DL, Daenke S, et al. (1997) CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics. J Exp Med 185:393-403
    • (1997) J Exp Med , vol.185 , pp. 393-403
    • Van Der Merwe, P.A.1    Bodian, D.L.2    Daenke, S.3
  • 14
    • 0028484545 scopus 로고
    • CLTA-4 can function as a negative regulator of T cell activation
    • Walunas TL, Lenschow DJ, Bakker CY, et al. (1994) CLTA-4 can function as a negative regulator of T cell activation. Immunity 1:405-413
    • (1994) Immunity , vol.1 , pp. 405-413
    • Walunas, T.L.1    Lenschow, D.J.2    Bakker, C.Y.3
  • 15
    • 0029120245 scopus 로고
    • CD28 and CTLA-4 have opposing effects on the response of T-cells to stimulation
    • Krummel MF, Allison JP (1995) CD28 and CTLA-4 have opposing effects on the response of T-cells to stimulation. J Exp Med 182:459-465
    • (1995) J Exp Med , vol.182 , pp. 459-465
    • Krummel, M.F.1    Allison, J.P.2
  • 16
    • 0028791059 scopus 로고
    • CTLA-4 deficiency causes lymphoproliferative disorder with early lethality
    • 1995
    • Waterhouse P, Penninger JM, Timms E, et al. (1995) CTLA-4 deficiency causes lymphoproliferative disorder with early lethality. Science 1995; 270:985-988
    • (1995) Science , vol.270 , pp. 985-988
    • Waterhouse, P.1    Penninger, J.M.2    Timms, E.3
  • 17
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role for CLTA-4
    • Tivol EA, Borriello F, Schweitzer AN, et al. (1995) Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role for CLTA-4. Immunity 3:541-547
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3
  • 18
    • 0036301503 scopus 로고    scopus 로고
    • CLTA-4: New insights into its biological function and use in tumor immunotherapy
    • Egen JG, Kuhns MS, Allison JP. (2002) CLTA-4: new insights into its biological function and use in tumor immunotherapy. Nat Immunol 3:611-618
    • (2002) Nat Immunol , vol.3 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 19
    • 0037154747 scopus 로고    scopus 로고
    • T cell receptor signaling precedes immunological synapse formation
    • Lee KH, Holdorf AD, Dustin ML, et al. (2002) T cell receptor signaling precedes immunological synapse formation. Science 295:1539-1542
    • (2002) Science , vol.295 , pp. 1539-1542
    • Lee, K.H.1    Holdorf, A.D.2    Dustin, M.L.3
  • 20
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by CTLA-4 blockade
    • Leach DR, Krummel MF, Allison JP (1996) Enhancement of antitumor immunity by CTLA-4 blockade. Science 271:1734-1736
    • (1996) Science , vol.271 , pp. 1734-1736
    • Leach, D.R.1    Krummel, M.F.2    Allison, J.P.3
  • 21
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-CTLA-4 and GM-CSF producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • van Elsas A, Hurwitz AA, Allison JP (1999) Combination immunotherapy of B16 melanoma using anti-CTLA-4 and GM-CSF producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 190:355-366
    • (1999) J Exp Med , vol.190 , pp. 355-366
    • Van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 22
    • 33645381024 scopus 로고    scopus 로고
    • Human/SCID chimeric models for preclinical evaluation of anti-cancer therapies: Applications, limitations and future directions
    • Bankert RB, Egilmez NK, Hess SD (2001) Human/SCID chimeric models for preclinical evaluation of anti-cancer therapies: Applications, limitations and future directions. Trends Immunol 22:368-393
    • (2001) Trends Immunol , vol.22 , pp. 368-393
    • Bankert, R.B.1    Egilmez, N.K.2    Hess, S.D.3
  • 23
    • 0036569592 scopus 로고    scopus 로고
    • CD4+ effector T-cells mediate an indirect IL-12 and IFN-gamma-dependent suppression of autologous lung tumor xenografts in SCID mice
    • Egilmez NK, Hess SD, Chen FA, et al. (2002) CD4+ effector T-cells mediate an indirect IL-12 and IFN-gamma-dependent suppression of autologous lung tumor xenografts in SCID mice. Cancer Res 62:2611-2617
    • (2002) Cancer Res , vol.62 , pp. 2611-2617
    • Egilmez, N.K.1    Hess, S.D.2    Chen, F.A.3
  • 24
    • 0030740303 scopus 로고    scopus 로고
    • Antitumor immune response of human peripheral blood lymphocytes co-engrafted with tumor nito severe immunodeficient mice
    • Iwanuma Y, Chen FA, Egilmez NK, et al (1997) Antitumor immune response of human peripheral blood lymphocytes co-engrafted with tumor nito severe immunodeficient mice. Cancer Research 57:2937-2942
    • (1997) Cancer Research , vol.57 , pp. 2937-2942
    • Iwanuma, Y.1    Chen, F.A.2    Egilmez, N.K.3
  • 25
    • 0026486220 scopus 로고
    • Co-expression and functional cooperation of CTLA-4 and CD28 on activated T-lymphocytes
    • Linsley PS, Greene JL, Tan P, et al. (1992) Co-expression and functional cooperation of CTLA-4 and CD28 on activated T-lymphocytes. J Exp Med 176:1595-1604
    • (1992) J Exp Med , vol.176 , pp. 1595-1604
    • Linsley, P.S.1    Greene, J.L.2    Tan, P.3
  • 26
    • 0030603986 scopus 로고    scopus 로고
    • Improved methods for the generation of dendritic cells from non-proliferating progenitors in human blood
    • Bender A, Sapp M, Schuler G, et al. (1996) Improved methods for the generation of dendritic cells from non-proliferating progenitors in human blood. J Immunol Methods 196:121-135
    • (1996) J Immunol Methods , vol.196 , pp. 121-135
    • Bender, A.1    Sapp, M.2    Schuler, G.3
  • 27
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T (1993) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
    • (1993) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 28
    • 0345368071 scopus 로고    scopus 로고
    • Is CTLA-4 a negative regulator for T-cell activation?
    • Liu Y (1997) Is CTLA-4 a negative regulator for T-cell activation? Immunol Today 18:569-72
    • (1997) Immunol Today , vol.18 , pp. 569-572
    • Liu, Y.1
  • 29
    • 0030694234 scopus 로고    scopus 로고
    • The emerging role of CTLA-4 as an immune attenuator
    • Thompson CB, Allison JP (1997) The emerging role of CTLA-4 as an immune attenuator. Immunity 7:445-450
    • (1997) Immunity , vol.7 , pp. 445-450
    • Thompson, C.B.1    Allison, J.P.2
  • 30
    • 0030853610 scopus 로고    scopus 로고
    • Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte associated molecule-4 blockade: The effect is manfiested only at the restricted tumor-bearing stages
    • Yang Y (1997) Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte associated molecule-4 blockade: The effect is manfiested only at the restricted tumor-bearing stages. Cancer Res 57:4036-4041
    • (1997) Cancer Res , vol.57 , pp. 4036-4041
    • Yang, Y.1
  • 31
    • 0032544067 scopus 로고    scopus 로고
    • CLTA-4 blockade synergizes with tumor-derived GM-CSF for treatment of an experimental mammary carcinoma
    • Hurwitz AA, Yu TF, Leach DR, Allison JP (1998) CLTA-4 blockade synergizes with tumor-derived GM-CSF for treatment of an experimental mammary carcinoma. Proc Natl Acad Sci USA (10067-10071)
    • (1998) Proc Natl Acad Sci USA , pp. 10067-10071
    • Hurwitz, A.A.1    Yu, T.F.2    Leach, D.R.3    Allison, J.P.4
  • 32
    • 0034194329 scopus 로고    scopus 로고
    • Combination immunotherapy of primary prostate cancer ina transgenic mouse model using CTLA-4 blockade
    • Hurwitz AA, Foster BA, Kwon ED, et al (2000) Combination immunotherapy of primary prostate cancer ina transgenic mouse model using CTLA-4 blockade. Cancer Res 60:2444-2448
    • (2000) Cancer Res , vol.60 , pp. 2444-2448
    • Hurwitz, A.A.1    Foster, B.A.2    Kwon, E.D.3
  • 33
    • 0032404099 scopus 로고    scopus 로고
    • Realization of the therapeutic potential of CTLA-4 blockade in low-dose chemotherapy-treated tumor-bearing mice
    • Mokyr MB, Kalinchenko T, Gorelik L, Bluestone JA (1998) Realization of the therapeutic potential of CTLA-4 blockade in low-dose chemotherapy-treated tumor-bearing mice. Cancer Research 58:5301-5304
    • (1998) Cancer Research , vol.58 , pp. 5301-5304
    • Mokyr, M.B.1    Kalinchenko, T.2    Gorelik, L.3    Bluestone, J.A.4
  • 34
    • 0038153907 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity induced by cytotoxic T lymphocyte associated antigen 4 blockade in patients with metastatic melanoma
    • Phan GQ, Yang JC, Sherry RM, et al (2003) Cancer regression and autoimmunity induced by cytotoxic T lymphocyte associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci USA 100:8372-8377
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8372-8377
    • Phan, G.Q.1    Yang, J.C.2    Sherry, R.M.3
  • 35
    • 0344341626 scopus 로고    scopus 로고
    • Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
    • Hodi FS, Mihm MC, Soiffer RJ, et al (2003) Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc Natl Acad Sci USA 100:4712-4717
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4712-4717
    • Hodi, F.S.1    Mihm, M.C.2    Soiffer, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.