The myocardial and vascular effects of bupivacaine, levobupivacaine, and ropivacaine using pressure volume loops

Anesthesia and Analgesia

Volumn 101, Issue 3, 2005, Pages 679-687

  Royse, Colin F ^a,b   Royse, Alistair G ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b Development and Advocacy   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; LEVOBUPIVACAINE; ROPIVACAINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL TONE; CARDIOTOXICITY; CARDIOVASCULAR EFFECT; CAVA VEIN OBSTRUCTION; CONTROLLED STUDY; DOSE RESPONSE; HEART EJECTION FRACTION; HEART INDEX; HEART LEFT VENTRICLE PRESSURE; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; HEART RIGHT ATRIUM PRESSURE; HEART STROKE VOLUME; LOCAL ANESTHESIA; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; RABBIT; VASCULAR RESISTANCE;

EID: 23944456558     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000157123.69327.6A     Document Type: Article

References (21)

1. Albright GA. Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. Anesthesiology 1979;51:285-7.
2. Graf BM, Abraham I, Eberbach N, et al. Differences in cardiotoxicity of bupivacaine and ropivacaine are the result of physicochemical and stereoselective properties. Anesthesiology 2002;96:1427-34.
3. Chang DH, Ladd LA, Copeland S, et al. Direct cardiac effects of intracoronary bupivacaine, levobupivacaine and ropivacaine in the sheep. Br J Pharmacol 2001;132:649-58.
4. D'Angelo R. Are the new local anesthetics worth their cost? Acta Anaesthesiol Scand 2000;44:639-41.
5. Auroy Y, Narchi P, Messiah A, et al. Serious complications related to regional anesthesia: results of a prospective survey in France. Anesthesiology 1997;87:479-86.
6. Baan J, van der Velde ET, Steendijk P. Ventricular pressure-volume relations in vivo. Eur Heart J 1992;13(Suppl E):2-6.
7. Kass DA. Clinical evaluation of left heart function by conductance catheter technique. Eur Heart J 1992;13(Suppl E):57-64.
8. Steendijk P, Baan J. Comparison of intravenous and pulmonary artery injections of hypertonic saline for the assessment of conductance catheter parallel conductance. Cardiovasc Res 2000;46: 82-9.
9. Steendijk P, Staal E, Jukema JW, Baan J. Hypertonic saline method accurately determines parallel conductance for dual-field conductance catheter. Am J Physiol Heart Circ Physiol 2001;281:H755-63.
10. Feldman HS, Arthur GR, Covino BG. Comparative systemic toxicity of convulsant and supraconvulsant doses of intravenous ropivacaine, bupivacaine, and lidocaine in the conscious dog. Anesth Analg 1989;69:794-801.
11. Groban L, Deal DD, Vernon JC, et al. Ventricular arrhythmias with or without programmed electrical stimulation after incremental overdosage with lidocaine, bupivacaine, levobupivacaine, and ropivacaine. Anesth Analg 2000;91:1103-11.
12. Ludbrook J. Repeated measurements and multiple comparisons in cardiovascular research. Cardiovasc Res 1994;28:303-11.
13. Murphy AM, Kogler H, Georgakopoulos D, et al. Transgenic mouse model of stunned myocardium. Science 2000;287:488-91.
14. Pinsky MR, Rico P. Cardiac contractility is not depressed in early canine endotoxic shock. Am J Respir Crit Care Med 2000; 161:1087-93.
15. Kuhlencordt PJ, Gyurko R, Han F, et al. Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice. Circulation 2001;104:448-54.
16. Scorsin M, Hagege AA, Dolizy I, et al. Can cellular transplantation improve function in doxorubicin-induced heart failure? Circulation 1998;98:II151-5; discussion II155-6.
17. Stewart J, Kellett N, Castro D. The central nervous system and cardiovascular effects of levobupivacaine and ropivacaine in healthy volunteers. Anesth Analg 2003;97:412-6.
18. Groban L, Deal DD, Vernon JC, et al. Does local anesthetic stereoselectivity or structure predict myocardial depression in anesthetized canines? Reg Anesth Pain Med 2002:460-8.
19. Scott DB, Lee A, Fagan D, et al. Acute toxicity of ropivacaine compared with that of bupivacaine. Anesth Analg 1989;69: 563-9.
20. Groban L, Deal DD, Vernon JC, et al. Cardiac resuscitation after incremental overdosage with lidocaine, bupivacaine, levobupivacaine, and ropivacaine in anesthetized dogs. Anesth Analg 2001;92:37-43.
21. Knudsen K, Beckman Suurkula M, Blomberg S, et al. Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers. Br J Anaesth 1997;78:507-14.