Alendronate decreases urine calcium and supersaturation in genetic hypercalciuric rats

Kidney International

Volumn 55, Issue 1, 1999, Pages 234-243

  Bushinsky, David A ^a   Neumann, Krystof J ^b   Asplin, John ^b   Krieger, Nancy S ^b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b NONE

Author keywords

Bisphosphate; Bone demineralization; Excretion of Ca; Hypercalciuria; Nephrolithiasis; Renal stones

Indexed keywords

ALENDRONIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BONE MINERALIZATION; CALCIUM EXCRETION; CALCIUM INTAKE; DRUG EFFECT; FEMALE; HYPERCALCIURIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STONE FORMATION;

EID: 0032953580     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.00247.x     Document Type: Article

References (55)

1. Coe FL, Bushinsky DA: Pathophysiology of hypercalciuria. Am J Physiol 247(Renal Fluid Electrol Physiol 16):F1-F13, 1984
2. Asplin JR, Favus MJ, Coe FL: Nephrolithiasis, in The Kidney, edited by Brenner BM, Philadelphia, W.B. Saunders Company, 1996, p 1893
3. Bushinsky DA: Renal lithiasis, in Kelly's Textbook of Medicine, edited by Kelly WF, New York, J.B. Lippincott, 1996, p 1024
4. Bushinsky DA, Krieger NS: Integration of calcium metabolism in the adult, in Disorders of Bone and Mineral Metabolism, edited by Coe FL, Favus MJ, New York, Raven Press, 1992, p 417
5. Monk RD, Bushinsky DA: Pathogenesis of idiopathic hypercalciuria, in Kidney Stones: Medical and Surgical Management, edited by Coe F, Favus M, Pak C, Parks J, Preminger G, New York, Raven Press, 1996, p 759
6. Favus MJ, Coe FL: Evidence for spontaneous hypercalciuria in the rat. Miner Electrolyte Metab 2:150-154, 1979
7. Asplin JR, Bushinsky DA, Singharetnam W, Riordon D, Parks JH, Coe FL: Relationship between supersaturation and crystal inhibition in hypercalciuric rats. Kidney Int 51:640-645, 1997
8. 3: A new characteristic of genetic hypercalciuric stone-forming rats. J Clin Invest 101:2223-2232, 1998
9. Tsuruoka S, Bushinsky DA, Schwartz GJ: Defective renal calcium reabsorption in genetic hypercalciuric rats. Kidney Int 51: 1540-1547, 1997
10. Bushinsky DA: Genetic hypercalciuric stone forming rats. Semin Nephrol 16:448-457, 1996
11. 3 in bone from genetic hypercalciuric rats. Am J Physiol 271(Cell Physiol 40):C130-C135, 1996
12. Bushinsky DA, Nilsson EL, Nakagawa Y, Coe FL, Grynpas M: Stone formation in genetic hypercalciuric rats. Kidney Int 48:1705-1713, 1995
13. Bushinsky DA, Kim M, Sessler NE, Nakagawa Y, Coe FL: Increased urinary saturation and kidney calcium content in genetic hypercalciuric rats. Kidney Int 45:58-65, 1994
14. Kim M, Sessler NE, Tembe V, Favus MJ, Bushinsky DA: Response of genetic hypercalciuric rats to a low calcium diet. Kidney Int 43:189-196, 1993
15. Li X-Q, Tembe V, Horwitz GM, Bushinsky DA, Favus MJ: Increased intestinal vitamin D receptor in genetic hypercalciuric rats: A cause of intestinal calcium hyperabsorption. J Clin Invest 91:661-667, 1993
16. Bushinsky DA, Favus MJ: Mechanism of hypercalciuria in genetic hypercalciuric rats: Inherited defect in intestinal calcium transport. J Clin Invest 82:1585-1591, 1988
17. Lau K, Thomas D, Langman C, Eby B: Pathophysiology of spontaneous hypercalciuria in laboratory rats: Role of deranged vitamin D metabolism. J Clin Invest 76:420-425, 1985
18. Lau YK, Eby BK: Tubular mechanism for the spontaneous hypercalciuria in laboratory rat. J Clin Invest 70:835-844, 1982
19. Bushinsky DA, Krieger NS: Role of the skeleton in calcium homeostasis, in The Kidney: Physiology and Pathophysiology, edited by Seldin DW, Giebisch G, New York, Raven Press, 1992, p 2395
20. Azuma Y, Chokki M, Ohta T, Kiyoki M: Effects of alendronate on plasma calcium levels, urinary calcium excretion and bone resorption markers in normal rats: Comparison with elcatonin, synthetic ecl calcitonin. Endocrinology 137:2586-2592, 1996
21. Muhlbauer, Bauss F, Schenk R, Janner M, Bosies E, Strein K, Fleisch H: BM 21.0955, a potent new bisphosphonate to inhibit bone resorption. J Bone Miner Res 6:1003-1011, 1991
22. Michalylova V, Ilkova P: Photometric determination of micro-amounts of calcium with arsenazo III. Anal Chim Acta 53:194-198, 1971
23. Heinegard D, Tiderstrom G: Determination of serum creatinine by a direct colorimetric method. Clin Chim Acta 43:305-310, 1973
24. Ichida T, Hine N: Improvement of Baginski's method for phosphorus determination. Clin Chim Acta 23:378-379, 1969
25. Fossati P, Prencipe L, Berti G: Use of 3,5-dichloro-2-hydroxybenzenesulfonic acid 4-aminophenazone chromogenic system in direct enzymic assay of uric acid in serum and urine. Clin Chem 26:227-231, 1980
26. Abernathy MH, Fowler RT: Micellar improvement of the calmagite compleximetric measurement of magnesium in plasma. Clin Chem 28:520-522, 1982
27. Ratliff CR, Hall FF: Ammonia in plasma enzymatic procedure. Selected Methods Clin Chem 9:85-90, 1982
28. Eisenman G, Rudin DO, Casby JU: Glass electrode for measuring sodium ion. Science 126:831-834, 1957
29. Stefanac Z, Simon W: Highly selective cation electrode systems based on in-vitro behavior of macrotetrolides in membranes. Chimica 20:436-440, 1966
30. Cotlove E: Chloride, in Standard Methods in Clinical Chemistry, edited by Seligson D, New York, Academic Press, 1961, p 81
31. Sugiura M, Yamamura H, Hirano K, Ito Y, Sasaki M, Morikawa M, Inoue M, Tsuboi M: Enzymatic determination of serum oxalate. Clin Chim Acta 105:393-399, 1980
32. Mollering H: Citrate, in Methods of Enzymatic Analysis (vol 2), edited by Bergmeyer HU, Weinhaim, Germany, Verlagsgellschaft, 1985, p 2
33. Ma RSW, Chan JCM: Endogenous sulphuric acid production: A method of measurement by extrapolation. Clin Biochem 6:82-87, 1973
34. Finlayson B: Calcium stones: Some physical and clinical aspects, in Calcium Metabolism in Renal Failure and Nephrolithiasis, edited by David DS, New York, Wiley, 1977, p 337
35. Werness PG, Brown CM, Smith LH, Finlayson B: Equil2: A basic computer program for the calculation of urinary saturation. J Urol 134:1242-1244, 1985
36. Brown CM, Ackermann DK, Purich DL: EQUIL93: A tool for experimental and clinical urolithiasis. Urol Res 22:119-126, 1994
37. Bushinsky DA, Lechleider RJ: Mechanism of proton-induced bone calcium release: Calcium carbonate dissolution. Am J Physiol 253(Renal Fluid Electrol Physiol 22):F998-F1005, 1987
38. Worcester EM, Nakagawa Y, Bushinsky DA, Coe FL: Evidence that serum calcium oxalate supersaturation is a consequence of oxalate retention in patients with chronic renal failure. J Clin Invest 77:1888-1896, 1986
39. 44Ca labeling of bone by scanning ion microprobe. Am J Physiol 259 (Endocrinol Metab 22):E586-E592, 1990
40. Widdowson EM, Dickerson JW: Chemical composition of the body, in Mineral Metabolism, edited by Comar CL, Bronner F, New York, Academic Press, 1964, p 1
41. Bushinsky DA: Disorders of calcium and phosphorus homeostasis, in Primer on Kidney Diseases, edited by Greenberg A, San Diego, Academic Press, 1997, p 106
42. Bushinsky DA: Bone disease in moderate renal failure: Cause, nature and prevention. Annu Rev Med 48:167-176, 1997
43. Coe FL, Parks JH, Moore ES: Familial idiopathic hypercalciuria. N Engl J Med 300:337-340, 1979
44. Pak CYC, McGuire J, Peterson R, Britton F, Harrod MJ: Familial absorptive hypercalciuria in a large kindred. J Urol 126:717-719, 1981
45. Aladjem M, Modan M, Lusky A, Georgi R, Orda S, Eshkol A, Lotan D, Boichis H: Idiopathic hypercalciuria: A familial generalized renal hyperexcretory state. Kidney Int 24:549-554, 1983
46. Mehes K, Szelid Z: Autosomal dominant inheritance of hypercalciuria. Eur J Pediatr 133:239-242, 1980
47. Birge SJ, Peck WA, Berman M, Whedon GD: Study of calcium absorption in man: A kinetic analysis and physiologic model. J Clin Invest 48:1705-1713, 1969
48. Pak CYC, East DA, Sanzenbacher LJ, Delea CS, Bartter FC: Gastrointestinal calcium absorption in nephrolithiasis. J Clin Endocrinol Metab 35:261-270, 1972
49. Pak CYC, Ohata M, Lawrence EC, Snyder W: The hypercalciurias: Causes, parathyroid functions, and diagnostic criteria. J Clin Invest 54:387-400, 1974
50. Zerwekh JE, Pak CYC: Selective effect of thiazide therapy on serum 1,25-dihydroxyvitamin D, and intestinal absorption in renal and absorptive hypercalciuria. Metabolism 29:13-17, 1980
51. Coe FL, Parks JH, Asplin JR: The pathogenesis and treatment of kidney stones. N Engl J Med 327:1141-1152, 1992
52. Barkin J, Wilson DR, Manuel MA, Bayley A, Murray T, Harrison J: Bone mineral content in idiopathic calcium nephrolithiasis. Miner Electrolyte Metab 11:19-24, 1985
53. Bataille P, Achard JM, Fournier A, Boudailliez B, Westell PF, Esper NE, Bergot C, Jans I, Lalau JD, Pettt J, Henon G, Jeantet MAL, Bouillon R, Sebert JL: Diet, vitamin D and vertebral mineral density in hypercalciuric calcium stone formers. Kidney Int 39:1193-1205, 1991
54. Borghi L, Meschi T, Guerra A, Maninettt L, Pedrazzoni M, Marcato A, Vescovi P, Novarini A: Vertebral mineral content in diet-dependent and diet-independent hypercalciuria. J Urol 146:1334-1338, 1991
55. Lawoyin S, Sismilich S, Browne R, Pak CY: Bone mineral content in patients with calcium urolithiasis. Metabolism 28:1250-1254, 1979