IgG autoantibodies to type VII collagen and an exclusive IgG3 reactivity to the laminin α3 chain in a patient with an autoimmune subepidermal blistering disease

Journal of the American Academy of Dermatology

Volumn 53, Issue 3, 2005, Pages 516-521

  Baican, Adrian ^a   Hirako, Yoshiaki ^b   Lazarova, Zelmira ^c   Yancey, Kim B ^c   Zillikens, Detlef ^d   Sitaru, Cassian ^d  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b NAGOYA UNIVERSITY   (Japan)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AZATHIOPRINE; COLCHICINE; COLLAGEN TYPE 7; COMPLEMENT; DAPSONE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; KALININ; LAMININ; LAMININ ALPHA3; PREDNISONE; UNCLASSIFIED DRUG;

ADULT; ANAMNESIS; ARTICLE; AUTOIMMUNE DISEASE; BULLOUS SKIN DISEASE; CASE REPORT; CLINICAL FEATURE; CONTROLLED STUDY; DERMOEPIDERMAL JUNCTION; FROZEN SECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; LABORATORY TEST; LEUKOCYTE ACTIVATION; MALE; MAXIMUM PERMISSIBLE DOSE; PRIORITY JOURNAL; PRURITUS; SERUM;

EID: 23944434751     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2005.05.001     Document Type: Article

References (29)

1. D.T. Woodley, R.A. Briggaman, E.J. O'Keefe, A.O. Inman, L.L. Queen, and W.R. Gammon Identification of the skin basement-membrane autoantigen in epidermolysis bullosa acquisita N Engl J Med 310 1984 1007 1013
2. E. Mooney, and W.R. Gammon Heavy and light chain isotypes of immunoglobulin in epidermolysis bullosa acquisita J Invest Dermatol 95 1990 317 319
3. P. Bernard, C. Prost, P. Aucouturier, N. Durepaire, F. Denis, and J.M. Bonnetblanc The subclass distribution of IgG autoantibodies in cicatricial pemphigoid and epidermolysis bullosa acquisita J Invest Dermatol 97 1991 259 263
4. W.R. Gammon, A.O. Inman, and C.E. Wheeler Jr. Differences in complement-dependent chemotactic activity generated by bullous pemphigoid and epidermolysis bullosa acquisita immune complexes: demonstration by leukocytic attachment and organ culture methods J Invest Dermatol 83 1984 57 61
5. C. Sitaru, A. Kromminga, T. Hashimoto, E.B. Brocker, and D. Zillikens Autoantibodies to type VII collagen mediate Fc gamma-dependent granulocyte activation and induce dermal-epidermal separation in cryosections of human skin Am J Pathol 161 2002 301 311
6. R. Hsu, Z. Lazarova, C. Yee, and K.B. Yancey Noncomplement fixing, IgG4 autoantibodies predominate in patients with anti-epiligrin cicatricial pemphigoid J Invest Dermatol 109 1997 557 561
7. Z. Lazarova, R. Hsu, C. Yee, and K.B. Yancey Human anti-laminin 5 autoantibodies induce subepidermal blisters in an experimental human skin graft model J Invest Dermatol 114 2000 178 184
8. I. Shimanovich, S. Mihai, G.J. Oostingh, T.T. Ilenchuk, E.B. Brocker, and G. Opdenakker Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid J Pathol 204 2004 519 527
9. L.S. Chan, J.C. Lapiere, M. Chen, T. Traczyk, A.J. Mancini, and A.S. Paller Bullous systemic lupus erythematosus with autoantibodies recognizing multiple skin basement membrane components, bullous pemphigoid antigen 1, laminin-5, laminin-6, and type VII collagen Arch Dermatol 135 1999 569 573
10. M.F. Jonkman, J. Schuur, F. Dijk, K. Heeres, M.C. de Jong, and J.B. van der Meer Inflammatory variant of epidermolysis bullosa acquisita with IgG autoantibodies against type VII collagen and laminin alpha3 Arch Dermatol 136 2000 227 231
11. N. Umemoto, T. Demitsu, S. Toda, M. Ohsawa, T. Noguchi, and M. Kakurai A case of nonscarring subepidermal blistering disease associated with autoantibodies reactive with both type VII collagen and laminin 5 Dermatology 207 2003 61 64
12. M. Megahed, and K. Scharffetter-Kochanek Epidermolysis bullosa acquisita - successful treatment with colchicine Arch Dermatol Res 286 1994 35 46
13. B.B. Cunningham, T.T. Kirchmann, and D. Woodley Colchicine for epidermolysis bullosa acquisita J Am Acad Dermatol 34 1996 781 784
14. K. Naito, S. Morioka, S. Ikeda, and H. Ogawa Experimental bullous pemphigoid in guinea pigs: the role of pemphigoid antibodies, complement, and migrating cells J Invest Dermatol 82 1984 227 230
15. F.M. Tatnall, P.C. Whitehead, M.M. Black, F. Wojnarowska, and I.M. Leigh Identification of the epidermolysis bullosa acquisita antigen by LH 7.2 monoclonal antibody: use in diagnosis Br J Dermatol 120 1989 533 539
16. P. Boukamp, R.T. Petrussevska, D. Breitkreutz, J. Hornung, A. Markham, and N.E. Fusenig Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line J Cell Biol 106 1988 761 771
17. M. Leverkus, K. Bhol, Y. Hirako, H. Pas, C. Sitaru, and G. Baier Cicatricial pemphigoid with circulating autoantibodies to beta4 integrin, bullous pemphigoid 180 and bullous pemphigoid 230 Br J Dermatol 145 2001 998 1004
18. Z. Lazarova, R. Hsu, C. Yee, and K.B. Yancey Antiepiligrin cicatricial pemphigoid represents an autoimmune response to subunits present in laminin 5 (alpha3beta3gamma2) Br J Dermatol 139 1998 791 797
19. Y. Hirako, K. Yoshino, D. Zillikens, and K. Owaribe Extracellular cleavage of bullous pemphigoid antigen 180/type XVII collagen and its involvement in hemidesmosomal disassembly J Biochem 133 2003 197 206
20. W.R. Gammon, C.C. Merritt, D.M. Lewis, W.M. Sams Jr., J.R. Carlo, and C.E. Wheeler Jr. An in vitro model of immune complex-mediated basement membrane zone separation caused by pemphigoid antibodies, leukocytes, and complement J Invest Dermatol 78 1982 285 290
21. C. Sitaru, E. Schmidt, S. Petermann, L.S. Munteanu, E.B. Brocker, and D. Zillikens Autoantibodies to bullous pemphigoid antigen 180 induce dermal-epidermal separation in cryosections of human skin J Invest Dermatol 118 2002 664 671
22. H.M. Grey, and H.G. Kunkel H chain subgroups of myeloma proteins and normal 7s gammaglobulin J Exp Med 120 1964 253 266
23. C.A. Janeway P. Travers M. Walport M. Shlomchik Immunobiology 5th ed. 2001 Garland New York
24. C. Sitaru, J. Powell, I. Shimanovich, S. Jainta, G. Kirtschig, and F. Wojnarowska Pemphigoid gestationis: maternal sera recognise epitopes restricted to the N-terminal portion of the extracellular domain of BP180 not present on its shed ectodomain Br J Dermatol 149 2003 420 422
25. K. Gandhi, M. Chen, S. Aasi, J.C. Lapiere, D.T. Woodley, and L.S. Chan Autoantibodies to type VII collagen have heterogenous subclass and light chain compositions and their complement-activating capacitities do not correlate with the inflammatory clinical phenotype J Clin Immunol 20 2000 416 423
26. J.S. van der Zee, P. van Swieten, and R.C. Aalberse Inhibition of complement activation by IgG4 antibodies Clin Exp Immunol 64 1986 415 422
27. J.S. Murray, and J.C. Brown Hyperimmunization alters Fc gamma antigenicity. Linkage to glycosylation J Immunol 141 1988 2668 2673
28. J. Lund, N. Takahashi, J.D. Pound, M. Goodall, H. Nakagawa, and R. Jefferis Oligosaccharide-protein interactions in IgG can modulate recognition by Fc gamma receptors FASEB J 9 1995 115 119
29. B.M. Kumpel, J.G. van de Winkel, N.A. Westerdaal, A.G. Hadley, J.M. Dugoujon, and A. Blancher Antigen topography is critical for interaction of IgG2 anti-red-cell antibodies with Fc gamma receptors Br J Haematol 94 1996 175 183