Antigen topography is critical for interaction of IgG2 anti-red-cell antibodies with Fcγ receptors

British Journal of Haematology

Volumn 94, Issue 1, 1996, Pages 175-183

  Kumpel, Belinda M ^a   Van De Winkel, Jan G J ^b   Westerdaal, Nomdo A C ^b   Hadley, Andrew G ^a   Dugoujon, J Michel ^c   Blancher, Antoine ^c  

^a NHS BLOOD AND TRANSPLANT   (United Kingdom)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c CHU PURPAN   (France)

Author keywords

Anti A; Anti D; Fc receptor; Functional activity; IgG2

Indexed keywords

BLOOD GROUP A ANTIBODY; FC RECEPTOR; IMMUNOGLOBULIN G2; RHESUS D ANTIBODY; RHESUS D ANTIGEN;

ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; ERYTHROCYTE; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0030037802     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.d01-1764.x     Document Type: Article

References (48)

1. Abramson, N. & Schur, P.H. (1972) The IyG, subclasses of red cell antibodies and relationship to monocyte binding. Blood, 40, 500-508.
2. Anderson, C.L., Ryan, D.H., Looney, R.J. & Leary, P.C. (1987) Structural polymorphism of the human monocyte 40 kilodalton Fc receptor for IgG. Journal of Immunology, 138, 2254-2256.
3. Anstee, D.J (1990) Blood-group-active surface molecules of the human red blood cell. Vox Sanguinis, 58, 1-20.
4. Anstee, D.J. (1995) Blood group antigens defined by the amino acid sequences of red cell surface proteins. Transfusion Medicine, 5, 1-13.
5. Arnaout, M.A., Todd, R.F., III, Dana, N., Melamed, J., Schlossman, S.F. & Colten, H.R. (1983) Inhibition of phagocytosis of complement C3- or immunoglobulin G-coated particles and of C3bi binding by monoclonal antibodies to a monocyte-granulocytc membrane glycoprotein (Mo1). Journal of Clinical Investigation, 72, 171-179.
6. Avent, N.D., Ridgwell, K., Tanner, M.J.A. & Anstee, D.J. (1990) cDNA cloning of a 30kDa erythrocyte membrane protein associated with Rh (Rhesus)-blood-group-antigen expression. Biochemical Journal, 271, 821-825.
7. Bredius, R.G.M., de Vries, C.E.E., Troelstra, A., van Alphen, L., Weening, R.S., van de Winkel, J.G.J. & Out T.A. (1993) Phagocytosis of Staphylococcus aureus and Haemophilus influenzae type B opsonised with polyelonal human IgG1 and IgG2 Antibodies. Journal of Immunology, 151, 1463-1472.
8. Brouwers, H.A.A., Overbeeke, M.A.M., Gemke, R.J.B.J., Maas, C.J., van Leeuwen, E.F. & Engelfriet, C.P. (1987) Sensitive methods for determining subclasses of IgG anti-A and anti-B in sera of blood-group-O women with a blood-group-A or -B child. British Journal of Haematology, 66, 267-270.
9. Brouwers, H.A.A., Overbeeke, M.A.M., Ouwehand, W.H., Keuning, K., van Ertbrugen, I., van Leeuwen, E.F., Stoop, J.W. & Hngelfriet, C.P. (1988) Maternal antibodies against fetal blood group antigens A or B: lytic activity of IgG subclasses in monocyte-driven cytotoxicity and correlation with ABO haemolytic disease of the newborn. British Journal of Haematology, 70, 465-469.
10. Burich, M.A., Anderson, H.J. & AuBuchon, J.P. (1986) Antibody elution using citric acid. Transfusion, 26, 116-117.
11. Devey, M.E. & Voak, D (1974) A critical study of the IgG subclasses of Rh anti-D antibodies formed in pregnancy and in immunized volunteers. Immunology, 27, 1075-1079.
12. Dugoujon, J.M., de Lange. G.G., Blancher, A., Alie-Daram, S. & Marty, Y. (1989) Characterization of an IgG2, G2m(23) anti-Rh-D antibody. Vox Sanguinis, 57, 133-136.
13. Fukuda, M. & Fukuda, M.N. (1981) Changes in cell surface glycoproteins and carbohydrate structures during the development and differentiation of human erythroid cells, Journal of Supramolecular Structure, 17, 313-324.
14. Gahmberg, C.G. (1983) Molecular characterization of the human red cell Rho(D) antigen. EMBO Journal, 2, 223-227.
15. Gergely, J., Sarmay, G., Rozsnyay, Z., Stanworth, D.R. & Klein, E. (1986) Binding characteristics and isotype specificity of Fc receptors on K cells. Molecular Immunology, 23, 1203-1209.
16. Hadley, A.G., Zupanska, B., Kumpel, B.M. & Leader, K.A. (1992) The functional activity of FcγRII and FcγRIII on subsets of human lymphocytes. Immunology, 76, 446-451.
17. Hadley, A.G., Kumpel, B.M. & Merry, A.H. (1988) The chemiluminescent response of human monocytes to red cells sensitized with monoclonal anti-Rh (D) antibodies. Clinical and Laboratory Haematology, 10, 377-384.
18. Hamilton, R.G. (1987) Human IgG subclass measurements in the clinical laboratory. Clinical Chemistry, 33, 1707-1725.
19. Hammarstrom, L. & Smith, C.I.E. (1986) IgG subclasses in bacterial infections. Monographs in Allergy, 19, 122-133.
20. Hughes-Jones, N.C., Gardner, B. & Lincoln, P. (1971) Observations on the number of available c, D and E antigen sites on red cells. Vox Sanguinis, 21, 210-216.
21. Jefferis, R. & Kumararatne, D.S. (1990) Selective IgG subclass deficiency: quantification and clinical relevance. Clinical and Experimental Immunology, 81, 357-367.
22. Jefferis, R., Reimer, C.B., Skvaril, F., de Lange, G., Ling, N.R., Lowe, J., Walker, M.R., Phillips, D.J., Aloisio, C.H., Wells, T.W., Vaerman, J.P., Magnusson, C.G., Kubagawa, H., Cooper, M., Vartdal, F., Vandvik, B., Haaijman, J.J., Makela, O., Sarnesto, A., Lando, Z., Gergely, J., Rajnavölgyi, E., Lásió, G., Radl, J. & Molinaro, G.A. (1985) Evaluation of monoclonal antibodies having specificity for human IgG subclasses: results of an IUIS/WHO collaborative study. Immunology Letters, 10, 233-252.
23. Jentoft, N. (1990) Why are proteins O-glycosylated? Trends in Biochemical Science, 15, 291-294.
24. Kumpel, B.M. (1990) A simple non-isotopic method for quantitation of red cell-bound immunoglobulin. Vox Sanguinis, 59, 34-38.
25. - volunteers. Blood, 86, 1701-1709.
26. Kumpel, B.M. & Hadley, A.G. (1990) Functional interactions of red cells sensitized by IgG1 and IgG3 human monoclonal anti-D with enzyme-modified human monocytes and FcR-bearing cell lines. Molecular Immunology, 27, 247-256.
27. Kumpel, B.M., Leader, K.A., Merry, A.M., Hadley, A.G., Poole, G.D., Blancher, A., Goossens, D., Hughes-Jones, N.C. & Bradley, B.A. (1989a) Heterogeneity in the ability of IgG1 monoclonal anti-D to promote lymphocyte-mediated red cell lysis. European Journal of Immunology, 19, 2283-2288.
28. Kumpel, B.M., Poole, G.D. & Bradley, B.A. (1989b) Human monoclonal anti-D antibodies. I. Their production, serology, quantitation and potential use as blood grouping reagents. British Journal of Haematology, 71, 125-129.
29. Lund, J., Winter, G., Jones, P.T., Pound, J.D., Tanaka, T., Walker, M.W., Artymiuk, P.J., Arata, Y., Burton, D.R., Jefferis, R. & Woof, J.M. (1991) Human FcγRI and FcγRII interact with distinct but overlapping sites on human IgG. Journal of Immunology, 147, 2657-2662.
30. Mattila, P.S., Seppala, I.J.T., Eklund, J. & Makela, O. (1985) Quantitation of immunoglobulin classes and subclasses in anti-Rh(D) antibodies. Vox Sanguinis, 48, 350-356.
31. Mollison, P.L., Engelfriet, C.P. & Contreras, M. (1993) Blood Transfusion in Clinical Medicine, 9th edn, p. 583. Blackwell Scientific Publications, Oxford.
32. Osborne, J.M., Chacko, G.W., Brandt, J.T. & Anderson, C.L. (1994) Ethnic variation in frequency of an allelic polymorphism of human FcγRIIA determined with allele specific oligonucleotide probes. Journal of Immunological Methods, 173, 207-217.
33. Parren, P.W.H.I., Warmerdam, P.A.M., Boeije, L.C.M., Arts, J., Westerdaal, N.A.C., Vlug, A., Capel, P.J.A., Aarden, L.A. & van de Winkel, J.G.J. (1992) On the interaction of IgG subclasses with the low affinity FcγRIIa (CD32) on human monocytes. neutrophils and platelets. Journal of Clinical Investigation, 90, 1537-1546.
34. Pumphrey, R. (1986) Computer models of the human immunoglobulins. Immunology Today, 7, 174-178.
35. Salmon, J.E., Edberg, J.C., Brogle, N.L. & Kimberley, R.P. (1992) Allelic polymorphisms of human Fcγ receptor IIA and Fcγ receptor IIB: independent mechanisms for differences in human phagocyte function. Journal of Clinical Investigation, 89, 1274-1281.
36. Sanders, L.A.M., Feldman, R.G., Voorhorst-Ogink, M.M., de Haas, M., Rijkers, G.T., Capel, P.J.A., Zegers, B.J.M. & van de Winkel, J.G.J. (1995) Human immunoglobulin G (IgG) Fc receptor IIA (CD52) polymorphism and IgG2-mediated bacterial phagocytosis by neutrophils. Infection and Immununity, 63, 73-81.
37. Sarmay, G., Jefferis, R., Klein, E., Benczur, M. & Gergely, J. (1985) Mapping the functional topography of Fc5 with monoclonal antibodies: localization of epitopes interacting with the binding sites of Fc receptor on human K cells. European Journal of Immunology, 15, 1037-1042.
38. Scott, M.L., Guest, A.R., King, M.J., Chambers, K.M., Davis, M.E. & Brazier, D.M. (1987) Characterisation of anti-A monoclonals by liquid-phase and solid-phase serology and radioimmune assay. Blood Transfusion and Immunohaematology, 30, 443-450.
39. Shakib, F. (1989) Structure-function relationships for IgG subclasses. Advances in Biosciences, 74, 113-122.
40. Thomson, A., Contreras, M., Gorick, B., Kumpel, B., Chapman, G.E., Lane, R.S., Teesdale, P., Hughs-Jones. N.C. & Mollison, P.I., (1990) Clearance of Rh D-positive red cells with monoclonal anti-D. Lancet, 336, 1147-1150.
41. van de Winkel, J.G.J. & Anderson, C.L. (1991) Biology of human immunoglobulin G Fc receptors. Journal of Leukocyte Biology, 49, 511-524.
42. van de Winkel, J.G.J. & Anderson, C.L. (1995) Cluster report: CD32. In: Leucocyte Typing V. (ed. by S. Schlossman, L. Boumsell, W. Gilks, J. M. Harian, T. Kishimoto, C. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. E. Tedder and R. F. Todd). Oxford University Press.
43. van de Winkel, J.G.J., Boonen, G.J.J.C., Janssen, P.L.W., Vlug, A., Hogg, N. & Tax, W.J.M. (1989) Activity of two types of Fc receptors. FcγRI and FcγRII, in human monocyte cytotoxicity to sensitized erythrocytes. Scandinavian Journal of Immunology, 29, 23-31.
44. van de Winkel, J.G.J. & Capel, P.J.A. (1993) Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications. Immunology Today, 14, 215-221.
45. van de Winkel, J.G.J., Tax, W.J.M., van Bruggen, M.C.J., van Roozendaal, C.E.P., Willems, H.W., Vlug, A., Capel, P.J.A. & Koene, A.P. (1987) Characterization of two Fc receptors for mouse immunoglobulins on human monocytes and cell lines. Scandinavian Journal of Immunology, 26, 663-672.
46. Warmerdam, P.A.M., van de Winkel, J.G.J., Vlug, A., Westerdaal, N.A.C. & Capel, P.J.A. (1991) A single amino acid in the second Ig-Iike domain of the human Fc receptor II is critical for human IgG2 binding. Journal of Immunology, 147, 1338-1343.
47. Wiener, E., Jolliffe, V.M., Scott, H.C.F., Kumpel, B.M., Thompson, K.M., Melamed. M.D. & Hughes-Jones, N.C. (1988) Differences between the activities of human monoclonal IgG1 and IgG3 anti-D antibodies of the Rh blood group system in their abilities to mediate effector functions of monocytes. Immunology, 65, 159-163.
48. Woof, J.M., Partridge, L.J., Jefferis, R. & Burton, D.R. (1986) Localisation of the monocyte-binding region on human immunoglobulin G. Molecular Immunology, 23, 319-330.